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ENTA

Enanta

$26.61

0.91 (3.54%)

, ABBV

AbbVie

$63.07

0.25 (0.40%)

08:32
10/03/16
10/03
08:32
10/03/16
08:32

Enanta to present new pre-clinical data on FXR agonist for NASH treatment

Enanta Pharmaceuticals (ENTA) announced that six poster presentations from Enanta's wholly-owned development programs in non-alcoholic steatohepatitis, or NASH, and hepatitis C virus have been accepted for presentation at the Liver Meeting(R), the Annual Meeting of the American Association for the Study of Liver Diseases taking place November 11-15. New data investigating Enanta's Farnesoid X Receptor EDP-305, currently in Phase 1 development, will be presented demonstrating its potency, selectivity and effects on fibrosis progression and lipid metabolism in pre-clinical models. A new FXR preclinical lead compound with enhanced potency, EP-024297, will also be characterized. Also being presented will be single- and multiple-ascending dose data in healthy volunteers, as well as preliminary viral kinetic data in genotype 1 and genotype 3 HCV patients treated with EDP-494, Enanta's novel host-targeted cyclophilin inhibitor. In addition, several presentations will report late-stage clinical data in genotypes 1-6 from AbbVie's (ABBV) chronic HCV clinical development program of regimens containing glecaprevir, Enanta's second HCV protease inhibitor, in combination with pibrentasvir, AbbVie's NS5A inhibitor.

ENTA

Enanta

$26.61

0.91 (3.54%)

ABBV

AbbVie

$63.07

0.25 (0.40%)

  • 04

    Oct

  • 06

    Nov

ENTA Enanta
$26.61

0.91 (3.54%)

10/23/15
JEFF
10/23/15
NO CHANGE
Target $85
JEFF
Buy
Jefferies 'strongly' advises buying AbbVie on the weakness
Jefferies analyst Jeffrey Holford "strongly' advises investors use yesterday's selloff in shares of AbbVie as a buying opportunity. The FDA warning letter applies to a very limited population within the hepatitis C market, which means it will have a limited impact on AbbVie's HCV franchise, Holford tells investors in a research note. Competitor Gilead (GILD) has also seen excess events in the Child-Pugh B population, the analyst points out. He keeps a Buy rating on AbbVie with an $85 price target. The stock closed yesterday down $5.57 to $48.26. Its partner Enanta Pharmaceuticals (ENTA) dropped $16.35 to $23.90.
10/23/15
10/23/15
UPGRADE

On The Fly: Analyst Upgrade Summary
Today's noteworthy upgrades include: Apple (AAPL) upgraded to Buy from Hold at Maxim... Cabela's (CAB) upgraded to Neutral from Sell at Goldman... EQT Corporation (EQT) upgraded to Buy from Accumulate at KLR Group... East West Bancorp (EWBC) upgraded to Outperform from Market Perform at Wells Fargo... Enanta (ENTA) upgraded to Outperform from Market Perform at JMP Securities... Equifax (EFX) upgraded on valuation, Veda deal, growth outlook at Stifel... KLA-Tencor (KLAC) upgraded to Neutral from Sell at Citi... Kimberly-Clark (KMB) upgraded to Buy from Hold at Societe Generale... Man Group (MNGPY) upgraded to Buy from Hold at Jefferies... McDonald's (MCD) upgraded to Overweight from Neutral at Piper Jaffray... Microsoft (MSFT) upgraded to Buy from Neutral at BofA/Merrill... Netgear (NTGR) upgraded to Outperform from Underperform at Raymond James... Pacific Biosciences (PACB) upgraded to Overweight from Neutral at Piper Jaffray... Progenics (PGNX) assumed with a Buy from Hold at Jefferies... Stanley Black & Decker (SWK) upgraded to Buy from Outperform at CLSA... Teck Resources (TCK) upgraded to Buy from Hold at BB&T... ZS Pharma (ZSPH) upgraded to Overweight from Equal Weight at Morgan Stanley... athenahealth (ATHN) upgraded to Outperform from Market Perform at Raymond James.
10/23/15
10/23/15
DOWNGRADE

On The Fly: Analyst Downgrade Summary
Today's noteworthy downgrades include: A. Schulman (SHLM) downgraded to Accumulate from Buy at Seaport Global... American Electric (AEP) downgraded to Neutral from Outperform at Credit Suisse... Applied Materials (AMAT) downgraded to Neutral from Buy at Citi... ArcelorMittal (MT) downgraded to Neutral from Outperform at Credit Suisse... BE Aerospace (BEAV) downgraded to Sector Perform from Outperform at RBC Capital... Banner Corp. (BANR) downgraded to Market Perform from Outperform at Keefe Bruyette... CEMEX (CX) downgraded to Equal Weight from Overweight at Barclays... Cabela's (CAB) downgraded to Market Perform from Outperform at Barrington... Cameron (CAM) downgraded to Market Perform from Outperform at Raymond James... Community Financial (TCFC) downgraded to Market Perform at Keefe Bruyette... Cypress Semiconductor (CY) downgraded to Buy from Strong Buy at Needham... Diana Shipping (DSX) downgraded to Hold from Buy at Jefferies... Dunkin' Brands (DNKN) downgraded to Neutral from Overweight at Piper Jaffray... Emerge Energy (EMES) downgraded to Neutral from Buy at Seaport Global... Enanta (ENTA) downgraded to Underweight from Equal Weight at Barclays... FireEye (FEYE) downgraded to Neutral from Outperform at Wedbush... Freescale (FSL) downgraded ahead of deal closing at Bernstein... GNC Holdings (GNC) downgraded to Neutral from Buy at Sterne Agee CRT... Heritage Financial (HFWA) downgraded to Market Perform at Keefe Bruyette... Huron (HURN) downgraded to Underperform from Outperform at Avondale... Independent Bank (IBTX) downgraded to Hold from Buy at Sandler O'Neill... KLX Inc. (KLXI) downgraded at RBC Capital... LaSalle Hotel (LHO) downgraded to Neutral from Outperform at Credit Suisse... LifePoint (LPNT) downgraded to Buy from Conviction Buy at Goldman... Mead Johnson (MJN) downgraded to Neutral from Outperform at Credit Suisse... Mindray Medical (MR) downgraded to Hold from Buy at Deutsche Bank... NASDAQ (NDAQ) downgraded to Market Perform from Outperform at Wells Fargo... Ocular Therapeutix (OCUL) downgraded to Equal Weight from Overweight at Morgan Stanley... Pandora (P) downgraded to Neutral from Buy at BofA/Merrill... Pebblebrook Hotel (PEB) downgraded to Neutral from Outperform at Credit Suisse... Plexus (PLXS) downgraded to Neutral from Buy at Goldman... Quidel (QDEL) downgraded to Hold from Buy at Craig-Hallum... Quotient Technology (QUOT) downgraded to Hold from Buy at Craig-Hallum... Raytheon (RTN) downgraded to Peer Perform from Outperform at Wolfe Research... Safe Bulkers (SB) downgraded to Hold from Buy at Jefferies... Sanmina (SANM) downgraded to Sell from Neutral at Citi... Skechers (SKX) downgraded to Neutral from Buy at Buckingham... Stericycle (SRCL) downgraded to Neutral from Outperform at Baird... Teck Resources (TCK) downgraded to Sell from Hold at Deutsche Bank... Trinity Biotech (TRIB) downgraded to Hold from Buy at Craig-Hallum... USG (USG) downgraded to Hold from Buy at Jefferies... Ultra Clean (UCTT) downgraded to Hold from Buy at Craig-Hallum... Under Armour (UA) downgraded to Hold from Buy at BB&T... Union Pacific (UNP) downgraded to Underperform at Avondale... Vishay (VSH) downgraded to Sell from Neutral at Citi... WABCO (WBC) downgraded to Buy from Conviction Buy at Goldman.
04/28/16
JMPS
04/28/16
DOWNGRADE
JMPS
Market Perform
Enanta downgraded to Market Perform from Outperform at JMP Securities
ABBV AbbVie
$63.07

0.25 (0.40%)

09/01/16
RAJA
09/01/16
INITIATION
Target $82
RAJA
Outperform
AbbVie initiated with an Outperform at Raymond James
Target $82.
09/02/16
09/02/16
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. AbbVie (ABBV) initiated with an Outperform at Raymond James. 2. Spark Therapeutics (ONCE) initiated with a Buy at Stifel. 3. Cornerstone OnDemand (CSOD) initiated with an Overweight at Piper Jaffray. 4. UR-Energy (URG) initiated with an Outperform at FBR Capital. 5. Energy Transfer Equity (ETE) reinstated with an Overweight at JPMorgan. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
09/08/16
JPMS
09/08/16
DOWNGRADE
Target $73
JPMS
Neutral
AbbVie downgraded to Neutral from Overweight at JPMorgan
JPMorgan analyst Chris Schott downgraded AbbVie (ABBV) to Neutral citing the stock's 10% rally year-to-date and limited near-term catalysts. AbbVie's profile is now better reflected at current valuation levels, Schott tells investors in a research note. He lowered his price target for the shares to $73 from $75. The analyst coupled the downgrade with an upgrade this morning of Eli Lilly (LLY) to Overweight.
10/03/16
LEER
10/03/16
NO CHANGE
LEER
Market Perform
AASLD abstracts hint at potential competitive threat to Gilead HCV, says Leerink
Leerink analyst Geoffrey Porges says abstracts for the American Association for the Study of Liver Diseases, or AASLD, meeting revealed very limited efficacy information about the new Hepatitis C regimens for Gilead (GILD), Merck (MRK) and AbbVie (ABBV). Nonetheless, the analyst believes the abstracts hint at the potential competitive threat to Gilead's HCV dominance. While the new 12-week HCV regimens may compete on price, the forthcoming 8-week regimens put the most pressure on Gilead's market share, Porges argues. He reiterates a Market Perform rating on Gilead's shares.

TODAY'S FREE FLY STORIES

LIOX

Lionbridge

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CMCSA

Comcast

$37.89

0.24 (0.64%)

, CMCSK

Comcast

16:54
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CMCSA

Comcast

$37.89

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CMCSK

Comcast

TWX

Time Warner

$97.28

0.6225 (0.64%)

LGF.A

Lionsgate

$27.18

-0.08 (-0.29%)

LGF.B

Lionsgate

$25.16

-0.19 (-0.75%)

DIS

Disney

$110.32

0.59 (0.54%)

FOX

21st Century Fox

$30.23

0.23 (0.77%)

FOXA

21st Century Fox

$30.61

0.27 (0.89%)

VIA

Viacom

VIAB

Viacom

$43.89

0.03 (0.07%)

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WAT

Waters

$156.40

1.51 (0.97%)

16:38
02/26/17
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  • 02

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CR

Crane

$73.21

1.18 (1.64%)

16:36
02/26/17
02/26
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  • 02

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DBOEY

Deutsche Boerse

$8.60

-0.045 (-0.52%)

16:34
02/26/17
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BCO

Brink's

$52.00

0.7 (1.36%)

16:33
02/26/17
02/26
16:33
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Conference/Events
Brink's to host investor day »

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  • 02

    Mar

XOM

Exxon Mobil

$81.08

-0.7 (-0.86%)

16:28
02/26/17
02/26
16:28
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16:28
Conference/Events
Exxon Mobil to host analyst meeting with a conference call hook-up »

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TXMD

TherapeuticsMD

$5.84

0.2 (3.55%)

16:22
02/26/17
02/26
16:22
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16:22
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TherapeuticsMD to host investor day »

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  • 01

    Mar

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  • 07

    May

MYL

Mylan

$42.16

-0.17 (-0.40%)

16:19
02/26/17
02/26
16:19
02/26/17
16:19
Conference/Events
Mylan to host investor day with a conference call hook-up »

CEO Bresch holds an…

03/08/13
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  • 01

    Mar

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    Mar

  • 28

    Mar

  • 03

    Sep

  • 09

    Oct

MCD

McDonald's

$128.65

0.38 (0.30%)

16:16
02/26/17
02/26
16:16
02/26/17
16:16
Conference/Events
McDonald's to host investor meeting »

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HSY

Hershey

$108.90

0.25 (0.23%)

16:13
02/26/17
02/26
16:13
02/26/17
16:13
Conference/Events
Hershey to hold a webcast »

Incoming CEO Michelle…

03/08/13
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03/08/13
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03/06/13
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  • 01

    Mar

SSNLF

Samsung

, FB

Facebook

$135.44

0.08 (0.06%)

16:10
02/26/17
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16:10
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16:10
Hot Stocks
Samsung introduces Gear VR with controller »

Samsung (SSNLF) announced…

SSNLF

Samsung

FB

Facebook

$135.44

0.08 (0.06%)

03/08/13
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03/06/13
Citigroup
03/06/13
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  • 27

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  • 06

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SSNLF

Samsung

16:08
02/26/17
02/26
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Hot Stocks
Samsung announces Galaxy Tab S3, Galaxy Book tablets »

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  • 19

    Mar

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SSNLF

Samsung

, HAR

Harman

$111.44

0.34 (0.31%)

16:06
02/26/17
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Samsung, Harman announce audio collaboration for Galaxy devices »

Samsung (SSNLF) and…

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HAR

Harman

$111.44

0.34 (0.31%)

03/08/13
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  • 19

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EFX

Equifax

$129.38

0.16 (0.12%)

16:06
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Equifax management to meet with investors »

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  • 28

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  • 01

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MRK

Merck

$66.16

0.31 (0.47%)

16:03
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  • 02

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EFX

Equifax

$129.38

0.16 (0.12%)

16:03
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Equifax management to meet with investors »

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  • 28

    Feb

NOK

Nokia

$5.14

-0.01 (-0.19%)

15:58
02/26/17
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  • 27

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TGT

Target

$66.51

1.53 (2.35%)

15:45
02/26/17
02/26
15:45
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15:45
Conference/Events
Target to hold a financial community meeting »

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  • 27

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  • 19

    Mar

GPRO

GoPro

$9.43

-0.14 (-1.46%)

15:42
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  • 28

    Feb

LGND

Ligand

$100.38

-2.46 (-2.39%)

15:40
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  • 28

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  • 02

    Mar

HURN

Huron

$44.30

-0.8 (-1.77%)

15:39
02/26/17
02/26
15:39
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15:39
Conference/Events
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  • 28

    Feb

ENS

EnerSys

$75.98

-0.77 (-1.00%)

15:36
02/26/17
02/26
15:36
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15:36
Conference/Events
EnerSys to host investor day »

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  • 28

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  • 17

    Mar

ERIC

Ericsson

$6.45

-0.08 (-1.23%)

15:36
02/26/17
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Ericsson says selected by Batelco for mobile network enhancement »

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  • 27

    Feb

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    Mar

QCOM

Qualcomm

$57.22

0.08 (0.14%)

15:33
02/26/17
02/26
15:33
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15:33
Conference/Events
Qualcomm to hold an investor session at Mobile World Congress 2017 »

Management holds an…

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  • 27

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