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AMGN

Amgen

$167.34

0.53 (0.32%)

08:54
10/04/16
10/04
08:54
10/04/16
08:54

Amgen, Nuevolution announce strategic collaboration in oncology, neuroscience

Nuevolution AB announced that Amgen and Nuevolution have entered into a multiple target research collaboration to develop and commercialize novel therapeutics in the areas of oncology and neuroscience. Nuevolution will apply its Chemetics drug discovery platform to discover and advance potential therapeutics of interest to Amgen. The research collaboration brings together Nuevolution's proprietary drug discovery platform with Amgen's disease expertise and drug development capabilities. Under the terms of the agreement, Amgen has an exclusive option to obtain all rights to successfully developed programs. Nuevolution is eligible to receive a license fee payment upon option exercise and milestone payments upon achievement of specified research, development and commercial milestones, amounting up to $410M per target. Nuevolution would also be entitled to receive royalties on future sales. Additional financial details are not being disclosed. Nuevolution will be responsible for the early research phase and Amgen will work collaboratively with Nuevolution during late-stage research. Amgen will be fully responsible for preclinical development, clinical development and commercialization worldwide.

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    Nov

  • 19

    Jul

AMGN Amgen
$167.34

0.53 (0.32%)

09/01/16
09/01/16
NO CHANGE

Amgen's sBLA for Blincyto approved by FDA
Amgen's supplemental Biologics License Application for Blincyto has been approved by the FDA to include new data supporting the treatment of pediatric patients with Philadelphia chromosome-negative relapsed or refractory B-cell precursor acute lymphoblastic leukemia. This indication is approved under accelerated approval, and continued approval may be contingent upon verification of clinical benefit in subsequent trials. The approval is based on results from the Phase 1/2 '205, an open-label, multicenter, single-arm trial, which evaluated the efficacy and safety of BLINCYTO in pediatric patients with relapsed or refractory B-cell precursor ALL. Blincyto was granted breakthrough therapy, priority review and orphan drug designations by FDA, and is now approved in the U.S. for the treatment of Ph- relapsed or refractory B-cell precursor ALL. In November 2015, BLINCYTO was granted conditional marketing authorization in the European Union for the treatment of adults with Ph- relapsed or refractory B-cell precursor ALL.
09/27/16
GSCO
09/27/16
NO CHANGE
Target $206
GSCO
Conviction Buy
Goldman surprised by Amgen's Kyprolis outcome in first-line multiple myeloma
Last night, Amgen announced Phase 3 Kypolis CLARION study did not meet the primary endpoint in first-line multiple myeloma. Goldman analyst Terence Flynn was surprised by this outcome given the prior positive superiority data for Kyprolis versus Velcade in the Phase III ENDEAVOR trial. Flynn sees risk to his Kyprolis $1B sales estimate in a first-line setting, but awaits for additional details from the call and further information regarding another ongoing Phase III trial. He expects Amgen shares to be weak on the news but said the company has additional drivers beyond Kyprolis including Repatha for high cholesterol and Erenumab for migraine with additional data expected in 2H 2016 and Q1 2017. Flynn remains Conviction Buy rated on Amgen and maintains his $206 price target.
09/27/16
PIPR
09/27/16
NO CHANGE
PIPR
Overweight
Amgen's Kyprolis in good shape despite trial miss, says Piper Jaffray
Piper Jaffray analyst Joshua Schimmer says Amgen's Kyprolis is still likely to be viewed as a "potent backbone, with the right drugs" after a Phase 3 study in front-line myeloma failed to reach its primary endpoint. The analyst believes the impact of the failed trial on Kyprolis use will be limited and he reiterates an Overweight rating on Amgen.
09/29/16
PIPR
09/29/16
NO CHANGE
Target $10
PIPR
Overweight
Arrowhead price target raised to $10 from $8 at Piper Jaffray
Piper Jaffray analyst Edward Tenthoff raised his price target for Arrowhead Pharmaceuticals (ARWR) to $10 after the company licensed two preclinical cardiovascular RNAi drugs with Amgen (AMGN). Amgen is the "ideal partner" and Arrowhead's balance sheet is now "meaningfully" strengthened, Tenthoff tells investors in a research note. He reiterates an Overweight rating on Arrowhead.

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GNCA

Genocea

$5.33

0.04 (0.76%)

20:43
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Genocea rating change at Stifel »

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CQH

Cheniere Energy Partners LP

$24.66

0.27 (1.11%)

20:27
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Cheniere Energy Partners LP initiated at BMO Capital »

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DAL

Delta Air Lines

$48.32

-0.15 (-0.31%)

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HA

Hawaiian Holdings

$37.45

-0.25 (-0.66%)

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ALK

Alaska Air

$74.79

0.04 (0.05%)

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LUV

Southwest

$55.12

0.19 (0.35%)

20:25
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DRI

Darden

$83.14

0.26 (0.31%)

, FDS

FactSet

$170.81

2.2 (1.30%)

20:25
09/25/17
09/25
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20:25
Earnings
Notable companies reporting before tomorrow's open »

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Darden

$83.14

0.26 (0.31%)

FDS

FactSet

$170.81

2.2 (1.30%)

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SAVE

Spirit Airlines

$34.15

0.44 (1.31%)

20:22
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20:22
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Spirit Airlines initiated at Macquarie »

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  • 27

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JBLU

JetBlue

$18.87

0.25 (1.34%)

20:22
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ALGT

Allegiant Travel

$133.95

3.85 (2.96%)

20:22
09/25/17
09/25
20:22
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20:22
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Allegiant Travel initiated at Macquarie »

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  • 26

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AAL

American Airlines

$47.70

0.64 (1.36%)

20:22
09/25/17
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American Airlines initiated at Macquarie »

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  • 02

    Oct

UAL

United Continental

$59.44

0.64 (1.09%)

20:21
09/25/17
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20:21
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20:21
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United Continental initiated at Macquarie »

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LUV

Southwest

$55.12

0.19 (0.35%)

20:10
09/25/17
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Southwest initiated at Macquarie »

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AMPH

Amphastar

$16.27

0.17 (1.06%)

, AVDL

Avadel Pharmaceuticals

$9.45

-0.16 (-1.66%)

18:59
09/25/17
09/25
18:59
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18:59
Hot Stocks
Amphastar announces FDA approval of Neostigmine Methylsulfate Injection, USP »

Amphastar (AMPH)…

AMPH

Amphastar

$16.27

0.17 (1.06%)

AVDL

Avadel Pharmaceuticals

$9.45

-0.16 (-1.66%)

03/08/13
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ACN

Accenture

$138.16

0.26 (0.19%)

18:58
09/25/17
09/25
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18:58
Hot Stocks
Accenture chief marketing & communications officer Taylor to retire Aug 31, 2018 »

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SPR

Spirit AeroSystems

$78.07

-0.38 (-0.48%)

, BA

Boeing

$254.32

-2.13 (-0.83%)

18:31
09/25/17
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18:31
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18:31
Hot Stocks
Spirit AeroSystems finalizes agreement with Boeing »

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SPR

Spirit AeroSystems

$78.07

-0.38 (-0.48%)

BA

Boeing

$254.32

-2.13 (-0.83%)

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MOH

Molina Healthcare

$64.54

-0.78 (-1.19%)

, UNH

UnitedHealth

$191.75

-1.28 (-0.66%)

18:17
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Senator Collins opposes Graham-Cassidy ACA repeal bill »

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MOH

Molina Healthcare

$64.54

-0.78 (-1.19%)

UNH

UnitedHealth

$191.75

-1.28 (-0.66%)

CNC

Centene

$90.33

-1.89 (-2.05%)

WCG

WellCare

$164.15

-3.01 (-1.80%)

CI

Cigna

$181.44

-1.3 (-0.71%)

ANTM

Anthem

$181.50

-1.36 (-0.74%)

HNT

Health Net

HUM

Humana

$237.21

-1.88 (-0.79%)

AET

Aetna

$151.98

-1.59 (-1.04%)

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18:15
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General news
Breaking General news story  »

Minneapolis Federal…

CATM

Cardtronics

$26.10

-3.17 (-10.83%)

18:13
09/25/17
09/25
18:13
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18:13
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Cardtronics rating change at William Blair »

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IVTY

Invuity

$7.80

-0.5 (-6.02%)

18:10
09/25/17
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18:10
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18:10
Recommendations
Invuity analyst commentary at Piper Jaffray »

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MOH

Molina Healthcare

$64.54

-0.78 (-1.19%)

, UNH

UnitedHealth

$191.75

-1.28 (-0.66%)

18:05
09/25/17
09/25
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18:05
Hot Stocks
CBO: Graham-Cassidy ACA repeal bill to reduce number of insured by 'millions' »

The Congressional Budget…

MOH

Molina Healthcare

$64.54

-0.78 (-1.19%)

UNH

UnitedHealth

$191.75

-1.28 (-0.66%)

CNC

Centene

$90.33

-1.89 (-2.05%)

WCG

WellCare

$164.15

-3.01 (-1.80%)

CI

Cigna

$181.44

-1.3 (-0.71%)

ANTM

Anthem

$181.50

-1.36 (-0.74%)

HNT

Health Net

HUM

Humana

$237.21

-1.88 (-0.79%)

AET

Aetna

$151.98

-1.59 (-1.04%)

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GPC

Genuine Parts

$93.22

5.24 (5.96%)

18:04
09/25/17
09/25
18:04
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18:04
Recommendations
Genuine Parts analyst commentary at RBC Capital »

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AA

Alcoa

$45.29

-0.09 (-0.20%)

, FCX

Freeport McMoRan

$13.89

-0.17 (-1.21%)

17:55
09/25/17
09/25
17:55
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17:55
Recommendations
Alcoa, Freeport McMoRan, Teck Resources, Newmont Mining, Warrior Met Coal, Cleveland-Cliffs analyst commentary at Morgan Stanley »

Morgan Stanley raising…

AA

Alcoa

$45.29

-0.09 (-0.20%)

FCX

Freeport McMoRan

$13.89

-0.17 (-1.21%)

TECK

Teck Resources

$21.24

-0.72 (-3.28%)

NEM

Newmont Mining

$38.63

0.74 (1.95%)

HCC

Warrior Met Coal

$24.11

0.76 (3.25%)

CLF

Cleveland-Cliffs

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17:55
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09/25
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17:55
Conference/Events
Federal Reserve Bank of Minneapolis President participates in a discussion »

Minneapolis Federal…

FTK

Flotek

$5.40

0.04 (0.75%)

17:49
09/25/17
09/25
17:49
09/25/17
17:49
Earnings
Flotek cuts Q3 revenue view by $5M, consensus $90.9M »

Flotek announced impacts…

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