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IONS

Ionis Pharmaceuticals

$36.38

0.72 (2.02%)

, ALNY

Alnylam

$70.30

1.73 (2.52%)

07:45
10/06/16
10/06
07:45
10/06/16
07:45

Ionis has no read through from negative Alnylam data, says Wells Fargo

After Ionis (IONS) competitor Alnylam Pharmaceuticals (ALNY) announced that it was terminating the development of its revusiran RNAi drug due to poor outcomes in clinical trials, Wells Fargo thinks that the news is "a significant positive" for Ionis because it eliminates a competitor. The firm says that Ionis' drug is significantly different than Alnylam's product, and it believes that Ionis' treatment appears to be superior. The firm keeps an Outperform rating on Ionis.

IONS

Ionis Pharmaceuticals

$36.38

0.72 (2.02%)

ALNY

Alnylam

$70.30

1.73 (2.52%)

  • 07

    Oct

  • 14

    Oct

  • 06

    Nov

IONS Ionis Pharmaceuticals
$36.38

0.72 (2.02%)

10/04/16
RBCM
10/04/16
NO CHANGE
Target $375
RBCM
Outperform
Biogen could rise $20 or more per share on SMA success, says RBC Capital
RBC Capital analyst Michael Yee expects the first presentation of data from Biogen's (BIIB) Phase III ENDEAR trial studying nusinersen, an investigational treatment for spinal muscular atrophy, or SMA, this week, potentially during the late breaker session at the WMS Congress on October 8. Biogen and partner Ionis Pharmaceuticals (IONS) already announced in August that the study in Type I infants hit the interim analysis and stopped early for positive data. The much larger opportunity in older children has data expected to read out in Spring 2017, noted Yee, who thinks Biogen can have upside from $10 to over $20 per share based on its SMA opportunity. Yee keeps an Outperform rating and $375 price target on Biogen shares.
10/06/16
BMOC
10/06/16
UPGRADE
BMOC
Outperform
Ionis Pharmaceuticals upgraded to Outperform from Market Perform at BMO Capital
10/06/16
PIPR
10/06/16
NO CHANGE
Target $46
PIPR
Overweight
Piper thinks Alnylam failure is positive for Ionis
Piper Jaffay analyst Joshua Schimmer thinks Alnylam Pharmaceuticals' (ALNY) "abrupt halt" of revusiran for TTR cardiomyopathy is likely a positive for Ionis Pharmaceuticals' (IONS) transthyretin program. The move "knocks out a competitive drug" while Ionis and GlaxoSmithKline (GSK) remain on their previously indicated timeline, Schimmer tells investors in a research note. The analyst at this point believes Alnylam's setback will be limited to revusiran and not read-through to other Gal-Nac programs or other TTR cardiomyopathy or polyneuropathy programs. He keeps an Overweight rating on Ionis with a $46 price target,
10/06/16
RBCM
10/06/16
NO CHANGE
RBCM
Alnylam news not a negative read through on other RNAi drugs, says RBC Capital
After Alnylam (ALNY) announced that it was discontinuing one of its Phase III RNAi drugs due to poor clinical outcomes, RBC Capital analyst Michael Yee does not thinks that the news indicates problems with all RNAi drugs. Rather, he thinks that RNAi was not the proper treatment for the disease that Alnylam was targeting. Other companies with RNAi treatments include The Medicines Company (MDCO0, Ionis Pharmaceuticals (IONS), Arrowhead (ARWR), and Arbutus Biopharma (ABUS).
ALNY Alnylam
$70.30

1.73 (2.52%)

10/06/16
JEFF
10/06/16
NO CHANGE
Target $43
JEFF
Buy
Alnylam setback has no read-through to Medicines Co., says Jefferies
Jefferies analyst Biren Amin believes Alnylam Pharmaceuticals' (ALNY) decision to stop revusiran due to lack of a treatment benefit has no read-through to The Medicines Co.'s (MDCO) PCSK9 program. Amin keeps a Buy rating on Medicines Co. with a $43 price target.
10/06/16
JEFF
10/06/16
NO CHANGE
Target $58
JEFF
Buy
Alnylam price target lowered to $58 from $86 at Jefferies
Jefferies analyst Gena Wang lowered her price target for Alnylam Pharmaceuticals to $58 from $86 following the termination of revusiran Phase 3 due to mortality imbalance. The analyst believes the setback, while "major," is likely to be program specific and not impact the company's other trials. She keeps a Buy rating on Alnylam.

TODAY'S FREE FLY STORIES

NVS

Novartis

$74.61

1.21 (1.65%)

, KO

Coca-Cola

$43.28

0.21 (0.49%)

20:25
04/24/17
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Earnings
Notable companies reporting before tomorrow's open »

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NVS

Novartis

$74.61

1.21 (1.65%)

KO

Coca-Cola

$43.28

0.21 (0.49%)

MMM

3M

$194.23

2.73 (1.43%)

MCD

McDonald's

$134.23

0.82 (0.61%)

LMT

Lockheed Martin

$276.21

3.12 (1.14%)

DD

DuPont

$79.37

0.72 (0.92%)

BIIB

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$276.86

3.92 (1.44%)

CAT

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2.49 (2.64%)

VLO

Valero

$66.82

1.59 (2.44%)

GLW

Corning

$27.52

0.5 (1.85%)

BHI

Baker Hughes

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PCAR

PACCAR

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1.97 (3.00%)

NTRS

Northern Trust

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2.02 (2.31%)

FITB

Fifth Third

$25.33

0.71 (2.88%)

FCX

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NLSN

Nielsen

$41.59

0.59 (1.44%)

CNC

Centene

$71.99

1.35 (1.91%)

PHM

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$23.08

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JBLU

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$21.75

0.22 (1.02%)

XRX

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$7.06

0.14 (2.02%)

PII

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$83.14

1.28 (1.56%)

AN

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$44.06

1.25 (2.92%)

GPK

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RAD

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TUP

Tupperware Brands

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1.47 (2.29%)

EAT

Brinker

$45.46

0.8 (1.79%)

AKS

AK Steel

$7.12

0.4 (5.95%)

SVU

Supervalu

$3.85

0.01 (0.26%)

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WBS

Webster Financial

$51.26

1 (1.99%)

19:50
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19:42
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Periodicals
Trump seeks 15% corporate tax rate, WSJ says »

President Donald Trump…

RYN

Rayonier

$28.81

-0.03 (-0.10%)

, LL

Lumber Liquidators

$22.66

-0.39 (-1.69%)

19:34
04/24/17
04/24
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19:34
Periodicals
White House to impose tariffs on Canadian lumber, FT says »

The Trump administration…

RYN

Rayonier

$28.81

-0.03 (-0.10%)

LL

Lumber Liquidators

$22.66

-0.39 (-1.69%)

DEL

Deltic Timber

$76.76

0.44 (0.58%)

WY

Weyerhaeuser

$34.89

0.33 (0.95%)

OSB

Norbord

$29.90

0.02 (0.07%)

PCH

Potlatch

$47.05

0.25 (0.53%)

UFPI

Universal Forest

$96.21

0.89 (0.93%)

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AAPL

Apple

$143.64

1.37 (0.96%)

, DLB

Dolby

$52.58

1.01 (1.96%)

19:20
04/24/17
04/24
19:20
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19:20
Periodicals
Apple taps NASA AR specialist to help run own AR efforts, Bloomberg says »

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AAPL

Apple

$143.64

1.37 (0.96%)

DLB

Dolby

$52.58

1.01 (1.96%)

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AMZN

Amazon.com

$907.41

8.88 (0.99%)

, AAPL

Apple

$143.64

1.37 (0.96%)

19:18
04/24/17
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19:18
Periodicals
Spotify job listings hint at hardware effort, Business Insider reports »

Music streaming service…

AMZN

Amazon.com

$907.41

8.88 (0.99%)

AAPL

Apple

$143.64

1.37 (0.96%)

SNAP

Snap

$21.20

0.27 (1.29%)

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ORCL

Oracle

$44.84

0.41 (0.92%)

19:09
04/24/17
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Oracle creating internal 'startup' to work on new tech, Bloomberg reports »

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MET

MetLife

$52.02

0.75 (1.46%)

18:57
04/24/17
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18:57
Periodicals
MetLife seeks delay of SIFI case after Trump orders review, Bloomberg says »

MetLife has asked a court…

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NGL

NGL Energy Partners

$21.70

0.1 (0.46%)

18:38
04/24/17
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NGL

NGL Energy Partners

$21.70

0.1 (0.46%)

18:37
04/24/17
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18:37
Earnings
NGL Energy Partners sees FY17 adjusted EBITDA $380M »

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KMB

Kimberly-Clark

$130.40

0.44 (0.34%)

18:20
04/24/17
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Kimberly-Clark priced for perfection, Barron's reports »

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DKL

Delek Logistics

18:16
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Delek Logistics raises quarterly cash distribution 1.5% to 69c per share »

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APU

AmeriGas

$45.83

0.04 (0.09%)

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AmeriGas raises dividend 1c to 95c »

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FSNUY

Fresenius SE

$20.56

0.89 (4.52%)

, MKGAY

Merck KGaA

$37.91

1.2299 (3.35%)

18:08
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FSNUY

Fresenius SE

$20.56

0.89 (4.52%)

MKGAY

Merck KGaA

$37.91

1.2299 (3.35%)

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NCOM

National Commerce

$37.90

0.15 (0.40%)

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National Commerce, Patriot bank sign merger agreement »

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NCOM

National Commerce

$37.90

0.15 (0.40%)

18:02
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Earnings
National Commerce reports Q1 EPS 45c, consensus 35c »

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NFLX

Netflix

$143.83

0.96 (0.67%)

, FB

Facebook

$145.47

1.79 (1.25%)

17:58
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FCC chairman expected to reveal net neutrality plans Wednesday, WSJ says »

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NFLX

Netflix

$143.83

0.96 (0.67%)

FB

Facebook

$145.47

1.79 (1.25%)

AMZN

Amazon.com

$907.41

8.88 (0.99%)

GOOG

Alphabet

$862.76

19.57 (2.32%)

GOOGL

Alphabet Class A

$878.93

19.98 (2.33%)

CMCSA

Comcast

$38.01

-0.15 (-0.39%)

CMCSK

Comcast

VZ

Verizon

$47.05

-0.2 (-0.42%)

T

AT&T

$40.02

0.09 (0.23%)

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MSFT

Microsoft

$67.53

1.13 (1.70%)

, GOOG

Alphabet

$862.76

19.57 (2.32%)

17:48
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Microsoft possibly eyes education push, 'CloudBook' system, Windows Central says »

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MSFT

Microsoft

$67.53

1.13 (1.70%)

GOOG

Alphabet

$862.76

19.57 (2.32%)

GOOGL

Alphabet Class A

$878.93

19.98 (2.33%)

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KMG

KMG Chemicals

$45.09

0.49 (1.10%)

17:47
04/24/17
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KMG Chemicals to acquire Flowchem for $495M in cash »

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KMG

KMG Chemicals

$45.09

0.49 (1.10%)

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Breaking Hot Stocks news story on KMG Chemicals »

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UIS

Unisys

$11.15

0.2 (1.83%)

, LLNW

Limelight Networks

$2.75

0.1 (3.77%)

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On The Fly: After Hours Movers »

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UIS

Unisys

$11.15

0.2 (1.83%)

LLNW

Limelight Networks

$2.75

0.1 (3.77%)

LXU

LSB Industries

$7.35

0.18 (2.51%)

SLCA

U.S. Silica

$41.55

1.04 (2.57%)

RRC

Range Resources

$27.23

-0.24 (-0.87%)

SANM

Sanmina

$39.95

1.35 (3.50%)

AA

Alcoa

$33.31

1.61 (5.08%)

IDRA

Idera Pharmaceuticals

$2.25

-0.07 (-3.02%)

HUM

Humana

$213.76

0.09 (0.04%)

ICHR

Ichor Holdings

$18.93

0.57 (3.10%)

CVS

CVS Health

$80.05

0.77 (0.97%)

ESRX

Express Scripts

$67.25

0.79 (1.19%)

ANTM

Anthem

$168.41

0.61 (0.36%)

CDNS

Cadence Design

$33.48

0.6 (1.82%)

ABX

Barrick Gold

$19.04

-0.19 (-0.99%)

ZION

Zions Bancorp

$41.96

1.11 (2.72%)

CNI

Canadian National

$75.66

0.94 (1.26%)

WHR

Whirlpool

$174.80

3.29 (1.92%)

CTRV

ContraVir Pharmaceuticals

$1.18

-0.23 (-16.31%)

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NWN

Northwest Natural Gas

$60.45

0.45 (0.75%)

17:43
04/24/17
04/24
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17:43
Hot Stocks
Northwest Natural Gas appoints Frank Burkhartsmeyeras CFO »

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RTN

Raytheon

$156.03

1.99 (1.29%)

17:41
04/24/17
04/24
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17:41
Hot Stocks
Raytheon awarded $111.3M government contract »

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GABC

German American Bancorp

$33.49

-15.7 (-31.92%)

17:39
04/24/17
04/24
17:39
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17:39
Hot Stocks
German American Bancorp raises quarterly dividend to 13c per share »

The company announced an…

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FRBA

First Bank

$13.35

-0.15 (-1.11%)

17:39
04/24/17
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17:39
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First Bank reports Q1 book value per share $7.95 »

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