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IONS

Ionis Pharmaceuticals

$36.38

0.72 (2.02%)

, ALNY

Alnylam

$70.30

1.73 (2.52%)

07:45
10/06/16
10/06
07:45
10/06/16
07:45

Ionis has no read through from negative Alnylam data, says Wells Fargo

After Ionis (IONS) competitor Alnylam Pharmaceuticals (ALNY) announced that it was terminating the development of its revusiran RNAi drug due to poor outcomes in clinical trials, Wells Fargo thinks that the news is "a significant positive" for Ionis because it eliminates a competitor. The firm says that Ionis' drug is significantly different than Alnylam's product, and it believes that Ionis' treatment appears to be superior. The firm keeps an Outperform rating on Ionis.

IONS

Ionis Pharmaceuticals

$36.38

0.72 (2.02%)

ALNY

Alnylam

$70.30

1.73 (2.52%)

  • 07

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    Nov

IONS Ionis Pharmaceuticals
$36.38

0.72 (2.02%)

10/04/16
RBCM
10/04/16
NO CHANGE
Target $375
RBCM
Outperform
Biogen could rise $20 or more per share on SMA success, says RBC Capital
RBC Capital analyst Michael Yee expects the first presentation of data from Biogen's (BIIB) Phase III ENDEAR trial studying nusinersen, an investigational treatment for spinal muscular atrophy, or SMA, this week, potentially during the late breaker session at the WMS Congress on October 8. Biogen and partner Ionis Pharmaceuticals (IONS) already announced in August that the study in Type I infants hit the interim analysis and stopped early for positive data. The much larger opportunity in older children has data expected to read out in Spring 2017, noted Yee, who thinks Biogen can have upside from $10 to over $20 per share based on its SMA opportunity. Yee keeps an Outperform rating and $375 price target on Biogen shares.
10/06/16
BMOC
10/06/16
UPGRADE
BMOC
Outperform
Ionis Pharmaceuticals upgraded to Outperform from Market Perform at BMO Capital
10/06/16
PIPR
10/06/16
NO CHANGE
Target $46
PIPR
Overweight
Piper thinks Alnylam failure is positive for Ionis
Piper Jaffay analyst Joshua Schimmer thinks Alnylam Pharmaceuticals' (ALNY) "abrupt halt" of revusiran for TTR cardiomyopathy is likely a positive for Ionis Pharmaceuticals' (IONS) transthyretin program. The move "knocks out a competitive drug" while Ionis and GlaxoSmithKline (GSK) remain on their previously indicated timeline, Schimmer tells investors in a research note. The analyst at this point believes Alnylam's setback will be limited to revusiran and not read-through to other Gal-Nac programs or other TTR cardiomyopathy or polyneuropathy programs. He keeps an Overweight rating on Ionis with a $46 price target,
10/06/16
RBCM
10/06/16
NO CHANGE
RBCM
Alnylam news not a negative read through on other RNAi drugs, says RBC Capital
After Alnylam (ALNY) announced that it was discontinuing one of its Phase III RNAi drugs due to poor clinical outcomes, RBC Capital analyst Michael Yee does not thinks that the news indicates problems with all RNAi drugs. Rather, he thinks that RNAi was not the proper treatment for the disease that Alnylam was targeting. Other companies with RNAi treatments include The Medicines Company (MDCO0, Ionis Pharmaceuticals (IONS), Arrowhead (ARWR), and Arbutus Biopharma (ABUS).
ALNY Alnylam
$70.30

1.73 (2.52%)

10/06/16
JEFF
10/06/16
NO CHANGE
Target $43
JEFF
Buy
Alnylam setback has no read-through to Medicines Co., says Jefferies
Jefferies analyst Biren Amin believes Alnylam Pharmaceuticals' (ALNY) decision to stop revusiran due to lack of a treatment benefit has no read-through to The Medicines Co.'s (MDCO) PCSK9 program. Amin keeps a Buy rating on Medicines Co. with a $43 price target.
10/06/16
JEFF
10/06/16
NO CHANGE
Target $58
JEFF
Buy
Alnylam price target lowered to $58 from $86 at Jefferies
Jefferies analyst Gena Wang lowered her price target for Alnylam Pharmaceuticals to $58 from $86 following the termination of revusiran Phase 3 due to mortality imbalance. The analyst believes the setback, while "major," is likely to be program specific and not impact the company's other trials. She keeps a Buy rating on Alnylam.

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GSK

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BHVN

Biohaven Pharmaceutical

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ESALY

Eisai

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PTNR

Partner Communications

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RARX

RA Pharmaceuticals

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VSTM

Verastem

$2.32

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BMY

Bristol-Myers

$56.64

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AGIO

Agios Pharmaceuticals

$59.18

1.76 (3.07%)

, CELG

Celgene

$134.31

0.63 (0.47%)

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AGIO

Agios Pharmaceuticals

$59.18

1.76 (3.07%)

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SNOW

Intrawest Resorts

$23.65

0.04 (0.17%)

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CI

Cigna

$169.61

-1.07 (-0.63%)

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FL

Foot Locker

$48.03

0.53 (1.12%)

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Nike

$52.85

0.45 (0.86%)

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$48.03

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$52.85

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AMZN

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$1,003.74

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RHT

Red Hat

$99.42

0.54 (0.55%)

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ALXN

Alexion

$126.07

-0.16 (-0.13%)

, UTHR

United Therapeutics

$131.59

-0.11 (-0.08%)

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ALXN

Alexion

$126.07

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UTHR

United Therapeutics

$131.59

-0.11 (-0.08%)

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AIZ

Assurant

$101.25

0.99 (0.99%)

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NCR

NCR Corp.

$38.64

0.09 (0.23%)

12:27
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ARQL

ArQule

$1.17

0.03 (2.63%)

, NLNK

NewLink Genetics

$7.36

-0.04 (-0.54%)

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$1.17

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NLNK

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$7.36

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$13.39

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CRSP

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Agios Pharmaceuticals

$59.18

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CELG

Celgene

$134.31

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STML

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$9.10

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CTIX

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$23.01

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TGTX

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HIMX

Himax

$8.17

-0.02 (-0.24%)

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AAPL

Apple

$146.28

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, AMZN

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IBM

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Oracle

$50.95

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VMW

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INTC

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$34.19

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AKAM

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$51.30

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THC

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$152.10

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WCG

WellCare

$183.28

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CI

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$169.61

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HUM

Humana

$238.42

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ANTM

Anthem

$190.17

-3.19 (-1.65%)

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$84.15

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$71.33

0.02 (0.03%)

UNH

UnitedHealth

$185.25

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REGN

Regeneron

$517.33

-9.2 (-1.75%)

CELG

Celgene

$134.31

0.63 (0.47%)

VRTX

Vertex

$133.50

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ALXN

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$126.07

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BIIB

Biogen

$280.32

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AMGN

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$22.25

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AKS

AK Steel

$6.65

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HIMX

Himax

$8.17

-0.02 (-0.24%)

04:55
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Himax management to meet with Roth Captial »

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ARQL

ArQule

$1.17

0.03 (2.63%)

, NLNK

NewLink Genetics

$7.36

-0.04 (-0.54%)

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European Hematology Association to hold a conference »

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ARQL

ArQule

$1.17

0.03 (2.63%)

NLNK

NewLink Genetics

$7.36

-0.04 (-0.54%)

BLUE

bluebird bio

$112.00

-6.5 (-5.49%)

XLRN

Acceleron

$34.10

0.15 (0.44%)

BLCM

Bellicum Pharmaceuticals

$13.39

-0.59 (-4.22%)

CRSP

CRISPR Therapeutics

$16.44

0.3 (1.86%)

AGIO

Agios Pharmaceuticals

$59.18

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CELG

Celgene

$134.31

0.63 (0.47%)

STML

Stemline

$9.10

0.6 (7.06%)

CTIX

Cellceutix

KPTI

Karyopharm

$9.97

0.01 (0.10%)

RARX

RA Pharmaceuticals

$23.01

0.01 (0.04%)

CDTX

Cidara Therapeutics

$6.70

-0.2 (-2.90%)

GBT

Global Blood Therapeutics

$29.85

0.6 (2.05%)

PTLA

Portola Pharmaceuticals

$56.06

17.81 (46.56%)

TGTX

TG Therapeutics

$11.95

-0.05 (-0.42%)

VSTM

Verastem

$2.32

-0.06 (-2.52%)

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ANTM

Anthem

$190.17

-3.19 (-1.65%)

18:58
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Anthem to pay $115M to settle data breach lawsuits, Reuters reports »

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SVU

Supervalu

$2.94

-0.04 (-1.34%)

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GILD

Gilead

$70.52

0.04 (0.06%)

18:14
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Gilead no longer a 'value trap,' Barron's reports »

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