Breaking News Instant updates and real-time market news.

NVS

Novartis

$78.29

-0.16 (-0.20%)

14:44
10/09/16
10/09
14:44
10/09/16
14:44

Novartis reports Phase 3 data on LEE011 in breast cancer

Novartis announced that results from the pivotal Phase III MONALEESA-2 study show LEE011, or ribociclib, plus letrozole significantly extended progression-free survival compared to a standard of care, letrozole, as a first-line treatment in postmenopausal women with hormone receptor positive, human epidermal growth factor receptor-2 negative advanced or metastatic breast cancer. The results demonstrate that LEE011 plus letrozole reduced the risk of death or progression by 44% over letrozole alone. The combination significantly improved PFS across all patient subgroups, regardless of disease characteristics or demographics. More than half of women with measurable disease taking LEE011 plus letrozole saw their tumor size shrink by at least 30% -- overall response rate in patients with measurable disease was 53% vs 37%. Most adverse events in the MONALEESA-2 trial were mild to moderate in severity, identified early through routine monitoring, and generally managed through dose interruption and reduction. The discontinuation rate due to adverse events in the MONALEESA-2 trial was 7.5% for LEE011 plus letrozole and 2.1% for letrozole alone. The most common grade 3/4 adverse events were as follows for LEE011 plus letrozole compared to letrozole alone: neutropenia 60% vs 1%, leukopenia 21% vs 1%, elevated alanine aminotransferase 9% vs 1%, lymphopenia 7% vs 1%, and elevated aspartate aminotransferase 6% vs 1%. Due to the significant extension of PFS and clinical benefit seen with LEE011, analysis of the primary endpoint in MONALEESA-2 was stopped early in May as recommended by the Independent Data Monitoring Committee. Follow up to measure overall survival is ongoing.

NVS Novartis
$78.29

-0.16 (-0.20%)

08/31/16
LEER
08/31/16
NO CHANGE
Target $61
LEER
Outperform
Teva price target lowered to $61 from $66 at Leerink
Leerink analyst Jason Gerberry lowered his price target for Teva (TEVA) to $61 from $66 on loss of Copaxone patent challenge as an upside catalyst. The analyst believes Teva's share price implies a generic entrant sometime in the second half of 2017 after losing an Inter Partes Review decision on two Copaxone 40mg anchor patents. In order to mitigate EPS downside in 2017-2018 and eliminate business uncertainty, Gerberry thinks the company should settle its Copaxone patent dispute with Novartis (NVS) and Momenta (MNTA), which he sees as "the most credible" generic threat. The analyst reiterates an Outperform rating on Teva's shares.
08/31/16
PIPR
08/31/16
NO CHANGE
PIPR
Piper's Schimmer unsure of impact from Novartis CAR-T shakeup
Piper Jaffray analyst Joshua Schimmer said he's struggling with the implications of the news that Novartis (NVS) is reportedly eliminating its Cell and Gene Therapy unit as a stand-alone entity, which is primarily focused on development of CAR-T and adoptive immunotherapies. On the one hand, removing a leading competitor is a positive for the rest of the field, Schimmer tells investors in a research note. On the other hand, the move by Novartis could signal "significant challenges" in the field, the analyst adds. Schimmer continues to prefer companies "with unique and differentiated approaches," namely Bellicum Pharmaceuticals (BLCM), Cellectis (CLLS), Lion Biotechnologies (LBIO), Amgen (AMGN), Celgene (CELG) and bluebird bio (BLUE). Juno Therapeutics (JUNO) and Kite Pharma (KITE) are down 6% and 5%, respectively, in midday trading.
09/02/16
LEER
09/02/16
NO CHANGE
LEER
Outperform
Teva third Copaxone patent invalidated as expected, says Leerink
Leerink analyst Jason Gerberry says Teva (TEVA) suffered a largely expected loss in its Copaxone 40mg patent battle, with the Patent Trial and Appeal Board, or PTAB, ruling a third patent invalid. The analyst believes the company will likely appeal the loss, along with PTAB rulings rendered last week that other Copaxone patents were invalid. Gerberry sees the bull case scenario of Teva securing patent exclusivity of the Copaxone 40mg as unlikely and says a settlement with Momenta (MNTA) and Novartis (NVS) is the most logical course of action to mitigate 2017-2018E EPS risk. He reiterates an Outperform rating on Teva's shares.
09/20/16
CHDN
09/20/16
INITIATION
Target $95
CHDN
Buy
Novartis initiated with a Buy at Chardan
Chardan initiated Novartis with a Buy and a $95 price target.

TODAY'S FREE FLY STORIES

PGNX

Progenics

$10.62

0.08 (0.76%)

, CLMS

Calamos

$8.24

-0.03 (-0.36%)

05:55
02/20/17
02/20
05:55
02/20/17
05:55
Hot Stocks
Progenics to replace Calamos in S&P 600 as of 2/20 close »

Calamos Asset Management…

PGNX

Progenics

$10.62

0.08 (0.76%)

CLMS

Calamos

$8.24

-0.03 (-0.36%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 21

    Feb

  • 22

    Feb

  • 23

    Feb

  • 01

    Mar

SFLY

Shutterfly

$48.06

0.66 (1.39%)

, VASC

Vascular Solutions

05:55
02/20/17
02/20
05:55
02/20/17
05:55
Hot Stocks
Shutterfly to replace Vascular Solutions in S&P 600 as of 2/20 close »

S&P MidCap 400…

SFLY

Shutterfly

$48.06

0.66 (1.39%)

VASC

Vascular Solutions

TFX

Teleflex

$179.91

1.86 (1.04%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 23

    Feb

AXP

American Express

$79.71

0.2 (0.25%)

, MAT

Mattel

$26.10

0.43 (1.68%)

04:55
02/20/17
02/20
04:55
02/20/17
04:55
Conference/Events
Toy Industry Association to hold fair »

International Toy Fair…

AXP

American Express

$79.71

0.2 (0.25%)

MAT

Mattel

$26.10

0.43 (1.68%)

HAS

Hasbro

$98.50

0.86 (0.88%)

COST

Costco

$175.86

0.11 (0.06%)

AMZN

Amazon.com

$845.07

0.93 (0.11%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 21

    Feb

  • 21

    Feb

  • 21

    Feb

  • 22

    Feb

  • 22

    Feb

  • 28

    Feb

  • 14

    Mar

  • 19

    Mar

  • 28

    Mar

NICE

NICE Systems

$69.04

-1.27 (-1.81%)

04:55
02/20/17
02/20
04:55
02/20/17
04:55
Conference/Events
NICE Systems management to meet with Oppenheimer »

Meeting to be held in the…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 20

    Feb

  • 27

    Feb

KHC

Kraft Heinz

$96.65

9.37 (10.74%)

, UN

Unilever; also tag UL

$48.79

6.47 (15.29%)

19:22
02/19/17
02/19
19:22
02/19/17
19:22
Hot Stocks
Kraft Heinz withdraws proposal to acquire Unilever »

Unilever (UN, UL) and…

KHC

Kraft Heinz

$96.65

9.37 (10.74%)

UN

Unilever; also tag UL

$48.79

6.47 (15.29%)

UL

Unilever; also tag UN

$48.53

5.96 (14.00%)

BRK.A

Berkshire Hathaway

$252,838.00

1338 (0.53%)

BRK.B

Berkshire Hathaway

$168.57

0.83 (0.49%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 20

    Feb

  • 19

    Mar

MNTA

Momenta

13:43
02/19/17
02/19
13:43
02/19/17
13:43
Conference/Events
Momenta to hold a conference call »

Management provides an…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 21

    Feb

RSPP

RSP Permian

$42.28

-0.54 (-1.26%)

12:48
02/19/17
02/19
12:48
02/19/17
12:48
Conference/Events
RSP Permian to hold a special shareholder meeting »

Special Shareholder…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 24

    Feb

  • 28

    Feb

  • 20

    Mar

AXP

American Express

$79.71

0.2 (0.25%)

, MAT

Mattel

$26.10

0.43 (1.68%)

04:55
02/19/17
02/19
04:55
02/19/17
04:55
Conference/Events
Toy Industry Association to hold fair »

International Toy Fair…

AXP

American Express

$79.71

0.2 (0.25%)

MAT

Mattel

$26.10

0.43 (1.68%)

HAS

Hasbro

$98.50

0.86 (0.88%)

COST

Costco

$175.86

0.11 (0.06%)

AMZN

Amazon.com

$845.07

0.93 (0.11%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 21

    Feb

  • 21

    Feb

  • 21

    Feb

  • 22

    Feb

  • 22

    Feb

  • 28

    Feb

  • 14

    Mar

  • 19

    Mar

  • 28

    Mar

QUNR

Qunar

$30.88

-0.14 (-0.45%)

15:28
02/18/17
02/18
15:28
02/18/17
15:28
Conference/Events
Qunar to host special shareholder meeting »

Special Shareholder…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 23

    Feb

REG

Regency Centers

$69.75

0.23 (0.33%)

, EQY

Equity One

$31.29

0.16 (0.51%)

15:21
02/18/17
02/18
15:21
02/18/17
15:21
Conference/Events
Equity One to host special shareholder meeting »

Special Shareholder…

REG

Regency Centers

$69.75

0.23 (0.33%)

EQY

Equity One

$31.29

0.16 (0.51%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 24

    Feb

EQY

Equity One

$31.29

0.16 (0.51%)

, REG

Regency Centers

$69.75

0.23 (0.33%)

15:18
02/18/17
02/18
15:18
02/18/17
15:18
Conference/Events
Regency Centers to host special shareholder meeting »

Special Shareholder…

EQY

Equity One

$31.29

0.16 (0.51%)

REG

Regency Centers

$69.75

0.23 (0.33%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

WIN

Windstream

$7.05

0.03 (0.43%)

, ELNK

EarthLink

$5.63

-0.01 (-0.18%)

15:12
02/18/17
02/18
15:12
02/18/17
15:12
Conference/Events
EarthLink to host special shareholder meeting »

Special Shareholder…

WIN

Windstream

$7.05

0.03 (0.43%)

ELNK

EarthLink

$5.63

-0.01 (-0.18%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 24

    Feb

  • 01

    Mar

  • 06

    Mar

ELNK

EarthLink

$5.63

-0.01 (-0.18%)

, WIN

Windstream

$7.05

0.03 (0.43%)

15:09
02/18/17
02/18
15:09
02/18/17
15:09
Conference/Events
Windstream to host special shareholder meeting »

Virtual Special…

ELNK

EarthLink

$5.63

-0.01 (-0.18%)

WIN

Windstream

$7.05

0.03 (0.43%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 01

    Mar

  • 06

    Mar

HNR

Harvest Natural

14:50
02/18/17
02/18
14:50
02/18/17
14:50
Conference/Events
Harvest Natural to host special shareholder meeting »

Special Shareholder…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

PH

Parker-Hannifin

$153.89

-0.52 (-0.34%)

, CLC

Clarcor

14:30
02/18/17
02/18
14:30
02/18/17
14:30
Conference/Events
Clarcor to host special shareholder meeting »

Special Shareholder…

PH

Parker-Hannifin

$153.89

-0.52 (-0.34%)

CLC

Clarcor

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 23

    Feb

AZN

AstraZeneca

$29.16

0.4 (1.39%)

, BAYRY

Bayer

$113.29

0.05 (0.04%)

04:55
02/18/17
02/18
04:55
02/18/17
04:55
Conference/Events
American Society of Clinical Oncology to hold a symposium »

2017 Genitourinary…

AZN

AstraZeneca

$29.16

0.4 (1.39%)

BAYRY

Bayer

$113.29

0.05 (0.04%)

BMY

Bristol-Myers

$54.59

0.31 (0.57%)

ESALY

Eisai

$54.40

0.205 (0.38%)

EXEL

Exelixis

$23.12

0.47 (2.08%)

GHDX

Genomic Health

$29.11

0.61 (2.14%)

MRK

Merck

$65.39

0.13 (0.20%)

MYGN

Myriad Genetics

$18.62

1.35 (7.82%)

NVS

Novartis

$77.20

0.47 (0.61%)

OPK

OPKO Health

$8.81

0.06 (0.69%)

PFE

Pfizer

PGNX

Progenics

$10.62

0.08 (0.76%)

SNY

Sanofi

$43.16

-0.38 (-0.87%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 19

    Feb

  • 21

    Feb

  • 21

    Feb

  • 21

    Feb

  • 22

    Feb

  • 23

    Feb

  • 27

    Feb

  • 01

    Mar

  • 02

    Mar

  • 08

    Mar

  • 09

    Mar

  • 15

    Mar

  • 17

    Mar

  • 23

    Mar

  • 29

    Mar

  • 01

    Apr

  • 10

    May

  • 27

    May

  • 14

    Jun

  • 26

    Jun

MDT

Medtronic

$78.88

0.89 (1.14%)

, NVO

Novo Nordisk

$35.46

0.02 (0.06%)

04:55
02/18/17
02/18
04:55
02/18/17
04:55
Conference/Events
Kenes International Organizers to hold a conference »

10th International…

MDT

Medtronic

$78.88

0.89 (1.14%)

NVO

Novo Nordisk

$35.46

0.02 (0.06%)

RHHBY

Roche

$30.53

0.02 (0.07%)

ABT

Abbott

$44.69

0.49 (1.11%)

SNY

Sanofi

$43.16

-0.38 (-0.87%)

LLY

Eli Lilly

$80.39

0.35 (0.44%)

DXCM

Dexcom

$81.89

0.5 (0.61%)

JNJ

Johnson & Johnson

$118.86

0.78 (0.66%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 20

    Feb

  • 21

    Feb

  • 21

    Feb

  • 21

    Feb

  • 22

    Feb

  • 23

    Feb

  • 24

    Feb

  • 24

    Feb

  • 27

    Feb

  • 27

    Feb

  • 28

    Feb

  • 06

    Mar

  • 07

    Mar

  • 09

    Mar

  • 17

    Mar

  • 21

    Mar

  • 27

    Mar

  • 29

    Mar

  • 19

    Apr

  • 26

    Jun

AXP

American Express

$79.71

0.2 (0.25%)

, MAT

Mattel

$26.10

0.43 (1.68%)

04:55
02/18/17
02/18
04:55
02/18/17
04:55
Conference/Events
Toy Industry Association to hold fair »

International Toy Fair…

AXP

American Express

$79.71

0.2 (0.25%)

MAT

Mattel

$26.10

0.43 (1.68%)

HAS

Hasbro

$98.50

0.86 (0.88%)

COST

Costco

$175.86

0.11 (0.06%)

AMZN

Amazon.com

$845.07

0.93 (0.11%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 21

    Feb

  • 21

    Feb

  • 21

    Feb

  • 22

    Feb

  • 22

    Feb

  • 28

    Feb

  • 14

    Mar

  • 19

    Mar

  • 28

    Mar

PKY

Parkway

$21.58

0.08 (0.37%)

18:20
02/17/17
02/17
18:20
02/17/17
18:20
Hot Stocks
Parkway to sell 49% interest in Houston Greenway portfolio for $512.1M »

Parkway announced that it…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 24

    Feb

  • 01

    Mar

VIA

Viacom

$47.00

-0.2 (-0.42%)

, VIAB

Viacom

$43.99

-0.17 (-0.38%)

18:15
02/17/17
02/17
18:15
02/17/17
18:15
Periodicals
Paramount CEO Brad Grey to leave studio as early as next week, Reuters says »

Brad Grey, chairman and…

VIA

Viacom

$47.00

-0.2 (-0.42%)

VIAB

Viacom

$43.99

-0.17 (-0.38%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 06

    Mar

MNTA

Momenta

, PFE

Pfizer

18:03
02/17/17
02/17
18:03
02/17/17
18:03
Hot Stocks
Momenta: Sandoz partner Pfizer receives FDA warning letter »

Momenta Pharmaceuticals…

MNTA

Momenta

PFE

Pfizer

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 17

    Feb

  • 21

    Feb

  • 21

    Feb

  • 21

    Feb

  • 02

    Mar

  • 09

    Mar

  • 17

    Mar

  • 23

    Mar

  • 01

    Apr

CI

Cigna

$143.56

-1.77 (-1.22%)

, ANTM

Anthem

$160.25

-3.52 (-2.15%)

17:53
02/17/17
02/17
17:53
02/17/17
17:53
Periodicals
Cigna claims Anthem attempted to harm its business, Bloomberg says »

Cigna (CI) has accused…

CI

Cigna

$143.56

-1.77 (-1.22%)

ANTM

Anthem

$160.25

-3.52 (-2.15%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

SCMP

Sucampo

$11.80

0.05 (0.43%)

, NILE

Blue Nile

17:50
02/17/17
02/17
17:50
02/17/17
17:50
Hot Stocks
Sucampo to replace Blue Nile in the S&P 600 as of February 23 open »

Sucampo Pharmaceuticals…

SCMP

Sucampo

$11.80

0.05 (0.43%)

NILE

Blue Nile

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 21

    Mar

VRML

Vermillion

$1.75

0.08 (4.79%)

17:39
02/17/17
02/17
17:39
02/17/17
17:39
Hot Stocks
Jack Schuler raises stake in Vermillion to 19.6% »

As of the date hereof,…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

SITO

SITO Mobile

$2.29

0.08 (3.62%)

17:34
02/17/17
02/17
17:34
02/17/17
17:34
Hot Stocks
SITO Mobile announces Jerry Hug resigned as CEO, names O'Connell interim »

Effective February 1,…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 01

    Mar

  • 29

    Mar

Get Full Fly Access

Breaking market intelligence sent straight to you
Our team of experts analyze every news story and filter out the noise to deliver real-time market moving news.
Up-to-date information on important industry events
Get real-time updates on events that are moving the market—from conferences and calls to syndicate announcements.
News focused on the companies in your portfolio
Create up to 12 portfolios with 150 stocks each, and see how active they are in market news.