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AVXS

AveXis

$47.51

2.35 (5.20%)

15:38
10/09/16
10/09
15:38
10/09/16
15:38

AveXis reports interim Phase 1 data on AVXS-101 in spinal muscular atrophy

AveXis provided an update on interim data from the ongoing Phase 1 trial of AVXS-101 in spinal muscular atrophy Type 1 as of September 15. The data were presented at the 21st International Annual Congress of the World Muscle Society. "For the first time, interim data from the trial were presented that highlighted patient achievement of key motor development milestones as of September 15. Two-thirds of patients in Cohort 2 - the proposed therapeutic dose - had achieved the ability to sit unassisted, including one patient whose achievement of this milestone was confirmed after September 15. In Cohort 2, 11 of 12 patients achieved head control, 7 of 12 patients could roll over completely and 11 of 12 patients could sit with support. Two patients are now walking independently, including one whose achievement of this milestone was confirmed after September 15. These two patients each achieved earlier and important developmental milestones such as crawling, standing with support, standing alone and walking with support," the company said. Data as of September 15 showed AVXS-101 continued to demonstrate a favorable safety profile and was generally well tolerated, with no new treatment-related safety or tolerability concerns identified.

  • 06

    Nov

AVXS AveXis
$47.51

2.35 (5.20%)

09/26/16
PIPR
09/26/16
NO CHANGE
Target $46
PIPR
Overweight
Ionis nusinersen program advancing faster than expected, says Piper Jaffray
After Biogen (BIIB) and Ionis (IONS) announced that Biogen has completed the rolling submission of a New Drug Application to the U.S. FDA for the approval of nusinersen, an investigational treatment for spinal muscular atrophy, Piper Jaffray analyst Joshua Schimmer said that the nusinersen program is advancing faster than many have expected. Nusinersen may launch before AveXis (AVXS) starts its next Phase 3 trial, added Schimmer, who believes nusinersen will emerge as a multi-billion dollar product. The analyst keeps an Overweight rating and $46 price target on Ionis shares.
09/28/16
JEFF
09/28/16
NO CHANGE
Target $50
JEFF
Buy
Jefferies parent survey shows interest in AveXis pivotal trial
Jefferies analyst Biren Amin conducted a survey of parents of spinal muscular atrophy patients amid investor questions surrounding AveXis' (AVXS) ability to enroll a pivotal trial with AVXS-101 given the open access program with nusinersen, the investigational drug being developed by Ionis Pharmaceuticals (IONS) and Biogen (BIIB). Parents value the option of nusinersen treatment but are also willing to enroll in clinical trials of AVXS-101, Amin tells investors in a research note, citing his survey of seven parents. A single arm trial of AVXS-101 was the most preferred clinical trial design for the upcoming Phase 3 of AVXS-101, he added. The analyst believes his parent responses suggest excitement over nusinersen but also a willingness to enroll into the AVXS-101 trials, especially if it is a single-arm trial. Parents were also attracted to AVXS-101 intravenous delivery, which could be a "meaningful advantage," Amin contends. The analyst keeps a Buy rating on AveXis with a $50 price target. The stock closed yesterday up 88c to $41.00. Amin caused a rally in AveXis shares on September 19 when writing about finding a video online of a spinal muscular atrophy baby walking that he believed to be a patient in the company's trial of AVXS-101.
10/06/16
GSCO
10/06/16
NO CHANGE
Target $71
GSCO
Buy
AveXis attractive acquisition target, price target to $71 at Goldman
Goldman analyst Salveen Richter said AveXis has two approaching catalysts coming up, the AVXS-101 update in SMA Type 1 at the World Muscle Society, or WMS, on October 8, and clarity on the AVXS-101 pivotal trial design in late October/early November. The analyst expects positive WMS data and raaised his probability of success to 60% from 45%. He expects compelling motor milestone data and pivotal trial visibility to make AveXis an attractive acquisition target and raised his price target to $71 from $46 on shares and reiterated his Buy rating.
10/07/16
GSCO
10/07/16
NO CHANGE
GSCO
Smid-cap Biotech sector upgraded to Attractive from Neutral at Goldman
Goldman analyst Salveen Richter upgraded the Smid-cap biotechnology to Attractive and said he favors and companies with near-term pipeline data or regulatory events where he has conviction.Names he recommends are Buy rated BioMarin (BMRN), bluebird bio (BLUE), GW Pharma (GWPH), Incyte (INCY), Kite (KITE), and Sage (SAGE).

TODAY'S FREE FLY STORIES

JUNO

Juno Therapeutics

$20.42

-0.01 (-0.05%)

23:25
12/05/16
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Conference/Events
Juno Therapeutics to host analyst and investor meeting »

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  • 05

    Dec

SGEN

Seattle Genetics

$66.26

-0.44 (-0.66%)

22:55
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22:55
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Conference/Events
Seattle Genetics to hold an investor reception »

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  • 05

    Dec

GNMSF

Genmab

$171.98

3.9767 (2.37%)

22:30
12/05/16
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22:30
Conference/Events
Genmab to hold data review meeting »

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  • 05

    Dec

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    Dec

TGTX

TG Therapeutics

$5.70

0.2 (3.64%)

22:25
12/05/16
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22:25
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22:25
Conference/Events
TG Therapeutics to hold an investor and analyst reception »

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  • 05

    Dec

RHHBY

Roche

$27.67

0.47 (1.73%)

20:25
12/05/16
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20:25
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20:25
Conference/Events
Roche to hold an analyst meeting »

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  • 05

    Dec

AZO

AutoZone

$776.42

-7.32 (-0.93%)

, HDS

HD Supply

$39.75

0.67 (1.71%)

20:25
12/05/16
12/05
20:25
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20:25
Earnings
Notable companies reporting before tomorrow's open »

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AZO

AutoZone

$776.42

-7.32 (-0.93%)

HDS

HD Supply

$39.75

0.67 (1.71%)

MIK

Michaels

$24.31

0.34 (1.42%)

TOL

Toll Brothers

$30.47

1.15 (3.92%)

BOBE

Bob Evans

$46.77

1.05 (2.30%)

CONN

Conn's

$11.20

0.4 (3.70%)

03/08/13
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  • 05

    Dec

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    Dec

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    Dec

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    Dec

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    Dec

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    Dec

  • 14

    Dec

  • 09

    Jan

GDDY

GoDaddy

$34.74

1.45 (4.36%)

20:14
12/05/16
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20:14
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Hot Stocks
GoDaddy acquires WP Curve »

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BDC

Belden

$74.99

0.9 (1.21%)

20:10
12/05/16
12/05
20:10
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20:10
Earnings
Belden sees FY17 adjusted EPS $5.00-$5.25, consensus $5.23 »

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  • 05

    Dec

SGMO

Sangamo

19:39
12/05/16
12/05
19:39
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19:39
Hot Stocks
Sangamo reports preclinical, manufacturing data on SB-525, says IND on track »

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  • 05

    Dec

SGEN

Seattle Genetics

$66.26

-0.44 (-0.66%)

, BMY

Bristol-Myers

$55.55

-0.41 (-0.73%)

19:38
12/05/16
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19:38
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19:38
Hot Stocks
Seattle Genetics, Bristol-Myers: Data supports ADCETRIS, Opdivo combo »

Seattle Genetics (SGEN)…

SGEN

Seattle Genetics

$66.26

-0.44 (-0.66%)

BMY

Bristol-Myers

$55.55

-0.41 (-0.73%)

03/08/13
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  • 05

    Dec

  • 07

    Dec

LGIH

LGI Homes

$32.34

0.45 (1.41%)

19:36
12/05/16
12/05
19:36
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19:36
Hot Stocks
LGI Homes reports November home closings up 28.9% y/y »

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CELG

Celgene

$116.56

-1.07 (-0.91%)

19:36
12/05/16
12/05
19:36
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19:36
Hot Stocks
Celgene reports analysis of three CC-486 studies »

Celgene announced results…

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  • 06

    Dec

BLUE

bluebird bio

$72.15

2.4 (3.44%)

19:35
12/05/16
12/05
19:35
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19:35
Hot Stocks
bluebird bio provides updates on HSC gene therapy programs »

bluebird bio provided…

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AGIO

Agios Pharmaceuticals

$49.88

-7.09 (-12.45%)

19:33
12/05/16
12/05
19:33
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19:33
Hot Stocks
Agios 'encouraged' by durable clinical activity of AG-120 »

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MRK

Merck

$60.25

-0.88 (-1.44%)

19:31
12/05/16
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19:31
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19:31
Hot Stocks
Merck: KEYNOTE-087 trial data shows oORR of 69%, CRR of 22.4% »

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  • 06

    Dec

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    Mar

TWX

Time Warner

$93.34

-0.46 (-0.49%)

, T

AT&T

$38.63

0.02 (0.05%)

19:29
12/05/16
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19:29
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19:29
Periodicals
Time Warner 'struggling to expand' HBO Now, NY Post says »

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TWX

Time Warner

$93.34

-0.46 (-0.49%)

T

AT&T

$38.63

0.02 (0.05%)

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  • 05

    Dec

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    Dec

BP

BP

, REPYY

Repsol

$13.88

0.25 (1.83%)

19:18
12/05/16
12/05
19:18
12/05/16
19:18
Periodicals
BP acquires Repsol stake in Indonesia LNG plant, Reuters says »

BP (BP) has purchased…

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BP

REPYY

Repsol

$13.88

0.25 (1.83%)

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FOSUF

Fosun

19:12
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19:12
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19:12
Hot Stocks
Liberty Mutual to acquire Fosun subsidiary Ironshore for roughly $3B »

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VZ

Verizon

$49.75

-0.06 (-0.12%)

, YHOO

Yahoo

$40.20

0.13 (0.32%)

18:54
12/05/16
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18:54
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18:54
Periodicals
AOL CEO 'cautiously optimistic' Verizon-Yahoo deal will go through, WSJ says »

AOL CEO Tim Armstrong…

VZ

Verizon

$49.75

-0.06 (-0.12%)

YHOO

Yahoo

$40.20

0.13 (0.32%)

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  • 05

    Dec

  • 24

    Jan

TUWOY

Tullow Oil

$2.06

0.109 (5.58%)

18:46
12/05/16
12/05
18:46
12/05/16
18:46
Downgrade
Tullow Oil rating change  »

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GBNK

Guaranty Bancorp

$22.15

0.75 (3.50%)

18:43
12/05/16
12/05
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18:43
Hot Stocks
Breaking Hot Stocks news story on Guaranty Bancorp »

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ATKR

Atkore

$20.48

-0.18 (-0.87%)

18:41
12/05/16
12/05
18:41
12/05/16
18:41
Syndicate
Atkore files to sell 8M shares of common stock for holders »

The offering is being…

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UTX

United Technologies

$107.42

-0.8 (-0.74%)

18:38
12/05/16
12/05
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18:38
Hot Stocks
United Technologies CEO: No quid pro quo on taxes in Carrier deal with Trump »

Says Carrier agreement…

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IPDN

Professional Diversity Network

$9.75

-0.01 (-0.10%)

18:37
12/05/16
12/05
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18:37
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Breaking Hot Stocks news story on Professional Diversity Network »

North Star cuts passive…

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DHXM

DHX Media

$5.05

-0.36 (-6.65%)

18:33
12/05/16
12/05
18:33
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18:33
Hot Stocks
Breaking Hot Stocks news story on DHX Media »

Luxor Capital cuts…

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