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BMY

Bristol-Myers

$55.43

0.38 (0.69%)

16:12
10/09/16
10/09
16:12
10/09/16
16:12

Bristol-Myers reports final primary analysis of CheckMate-026 lung cancer study

Bristol-Myers Squibb announced the final primary analysis of CheckMate -026, a trial investigating the use of Opdivo monotherapy as first-line therapy in patients with advanced non-small cell lung cancer whose tumors expressed PD-L1 greater or equal to 1%. The study was powered to assess progression-free survival for patients with greater or equal to 5% PD-L1 expression. The topline results from the study were previously disclosed and showed CheckMate -026 did not meet the primary endpoint of superior PFS compared to chemotherapy. In patients with greater than/equal to 5% PD-L1 expression, the median PFS was 4.2 months with Opdivo and 5.9 months with platinum-based doublet chemotherapy. Overall survival was 14.4 months for Opdivo versus 13.2 months for chemotherapy, and 60% of patients on the chemotherapy arm received subsequent Opdivo use after progression either through crossover or commercial access. The safety of Opdivo was consistent with the known safety profile of the drug in previous studies. Among all-treated patients, treatment-related adverse events of any grade and Grade 3/4 occurred in 71% and 18% of Opdivo-treated patients and 92% and 51% of chemotherapy-treated patients, respectively.

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BMY Bristol-Myers
$55.43

0.38 (0.69%)

09/12/16
JEFF
09/12/16
NO CHANGE
Target $57
JEFF
Hold
Jefferies cuts Bristol-Myers price target, upgrades AstraZeneca
Jefferies analyst Jeffrey Holford lowered his price target for Bristol-Myers Squibb (BMY) to $57 from $69 saying the stock is positioned for a "rough mid term ride." The analyst sees a "difficult catalyst" set for Bristol shares with "numerous" upcoming competitor read-outs in non-small cell lung cancer. The market could see worse than expected data from Bristol's CM-026 and CM-568 studies as well as better than expected data from AstraZeneca's (AZN) MYSTIC study and Roche's (RHHBY) Chemo-IO studies in the first half of 2017, Holford tells investors in a research note. He keeps a Hold rating on Bristol and upgraded this morning AstraZeneca to Buy from Hold. Holford prefers Astra for its immunology exposure.
09/20/16
SBSH
09/20/16
NO CHANGE
Target $70
SBSH
Buy
Bristol-Myers price target lowered to $70 from $75 at Citi
In a research note titled "Brace Yourself. Attractive Valuation but No Near-Term Respite.," Citi analyst Andrew Baum lowered his price target for shares of Bristol-Myers Squibb to $70 from $75. The analyst lowered his earnings forecasts by up to 8% to reflect the "limited supportive data" in the non-small cell lung cancer indication. Baum keeps a Buy rating on the shares as he views the valuation as attractive. He points out, however, the near-term news-flow is likely to be negative.
09/27/16
PIPR
09/27/16
NO CHANGE
Target $62
PIPR
Neutral
Bristol-Myers price target lowered to $62 from $65 at Piper Jaffray
Piper Jaffray analyst Richard Purkiss lowered his price target for Bristol-Myers Squibb (BMY) to $62 saying he sees the company ceding Opdivo's early-mover advantage in lung cancer to competitors. The analyst expects to see details from Roche's (RHHBY) positive OAK trial of Tecentriq vs. docetaxel in non-small cell lung cancer at the upcoming ESMO meeting. Purkiss also expects to see details from Merck's (MRK) positive KEYNOTE-024 trial of Keytruda. The analyst lowered his post-2016 Opdivo forecasts and reiterates a Neutral rating on Bristol shares.
09/28/16
ROTH
09/28/16
NO CHANGE
Target $23
ROTH
Buy
Nektar price target raised to $23 from $19 at Roth Capital
Roth Capital analyst Michael Higgins raised his price target for Nektar (NKTR) to $23 from $19 after the company and Bristol-Myers (BMY) announced a clinical collaboration to evaluate the combination of the latter's anti-PD-1 antibody, Opdivo, with NKTR-214. The analyst reiterates a Buy rating on Nektar's shares.

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CSCO

Cisco

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BMY

Bristol-Myers

$63.36

0.03 (0.05%)

18:12
09/22/17
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18:12
Hot Stocks
Bristol-Myers announces FDA approval of Opdivo »

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INSE

Inspired Entertainment

$13.60

0.3 (2.26%)

17:38
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Inspired Entertainment COO Wilson leaving by reason of redundancy »

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MNOV

MediciNova

$6.18

0.3 (5.10%)

17:30
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Breaking Syndicate news story on MediciNova »

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ISRG

Intuitive Surgical

$1,031.52

1.31 (0.13%)

17:25
09/22/17
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17:25
Conference/Events
Intuitive Surgical to host special shareholder meeting »

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GD

General Dynamics

$205.41

-0.31 (-0.15%)

17:21
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General Dynamics Electric Boat awarded $341.2M government contract modification »

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CHRS

Coherus Biosciences

$12.85

0.3 (2.39%)

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Breaking Syndicate news story on Coherus Biosciences »

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FIBK

First Interstate

$36.90

0.3 (0.82%)

17:18
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17:18
Syndicate
First Interstate files to sell $250M of Class A common stock »

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NRCIA

National Research, also tag NRCIB

$37.45

0.55 (1.49%)

, NRCIB

National Research, also tag NRCIA

$54.30

0.31 (0.57%)

17:08
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National Research launches metric to measure healthcare consumer loyalty »

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NRCIA

National Research, also tag NRCIB

$37.45

0.55 (1.49%)

NRCIB

National Research, also tag NRCIA

$54.30

0.31 (0.57%)

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CC

Chemours

$51.79

-0.16 (-0.31%)

, HON

Honeywell

$141.75

0.89 (0.63%)

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Chemours files appeal concerning SNAP 20 rule to regulate HFCs »

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CC

Chemours

$51.79

-0.16 (-0.31%)

HON

Honeywell

$141.75

0.89 (0.63%)

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AGN

Allergan

$204.65

1.99 (0.98%)

16:57
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HON

Honeywell

$141.75

0.89 (0.63%)

, CC

Chemours

$51.79

-0.16 (-0.31%)

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Honeywell, Chemours seek rehearing of D.C Court decision regarding SNAP program »

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HON

Honeywell

$141.75

0.89 (0.63%)

CC

Chemours

$51.79

-0.16 (-0.31%)

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JOE

Saint Joe Co.

$18.60

0.45 (2.48%)

16:46
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Breaking Hot Stocks news story on Saint Joe Co. »

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16:40
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General news
Moody's downgrades UK's rating to Aa2, changes outlook to stable »

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A

Agilent

$65.78

-0.14 (-0.21%)

, MRK

Merck

$65.13

-0.47 (-0.72%)

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Agilent

$65.78

-0.14 (-0.21%)

MRK

Merck

$65.13

-0.47 (-0.72%)

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TYHT

Shineco

$3.23

-0.45 (-12.23%)

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ARCI

Appliance Recycling

$1.16

0.03 (2.65%)

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RNVA

Rennova Health

$0.22

0.0086 (4.07%)

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ARCI

Appliance Recycling

$1.16

0.03 (2.65%)

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Breaking Hot Stocks news story on Appliance Recycling »

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16:30
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Options
Preliminary option volume of 13.9M today »

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EKSO

Ekso Bionics

$1.28

0.14 (12.28%)

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UNH

UnitedHealth

$193.03

-2.18 (-1.12%)

, AET

Aetna

$153.57

0.18 (0.12%)

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AET

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ANTM

Anthem

$182.86

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CI

Cigna

$182.74

0.61 (0.33%)

AAPL

Apple

$151.89

-1.5 (-0.98%)

FSLR

First Solar

$51.41

2.65 (5.43%)

FINL

Finish Line

$9.73

0.51 (5.53%)

ASND

Ascendis Pharma

$34.24

6.5 (23.43%)

VSAR

Versartis

$2.68

-18.925 (-87.62%)

ICPT

Intercept

$61.59

-12.11 (-16.43%)

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DLR

Digital Realty

$114.51

-1.72 (-1.48%)

16:19
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Breaking Syndicate news story on Digital Realty »

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$NSD

NASDAQ Market Internals

16:17
09/22/17
09/22
16:17
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16:17
Technical Analysis
NASDAQ market internals summary »

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TSS

TSYS

$69.09

0.28 (0.41%)

16:16
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TSYS announces resignation of COO Pamela Joseph »

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