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CLDX

Celldex

$4.14

-0.06 (-1.43%)

17:27
10/09/16
10/09
17:27
10/09/16
17:27

Celldex reports Phase 2 data on glembatumumab vedotin in melanoma

Celldex Therapeutics presented results from the company's Phase 2 study of glembatumumab vedotin in patients with stage III/IV checkpoint inhibitor-refractory, and, if applicable, BRAF/MEK inhibitor-refractory metastatic melanoma. The primary endpoint of the study -- 6 or more objective responses in the first 52 patients enrolled -- was exceeded. Seven of 62 patients experienced a confirmed response, and an additional 3 patients also experienced single timepoint responses. Median duration of response in this heavily pre-treated patient population was 6.0 months. 53% of patients experienced stable disease, with a minimum duration of six weeks. A 52% disease control rate was demonstrated. 52% of patients experienced tumor shrinkage. Median progression-free survival for all patients was 4.4 months. Patients who experienced rash in Cycle 1 experienced a 20% confirmed response rate and a more prolonged PFS of 5.5 months.

  • 09

    Oct

CLDX Celldex
$4.14

-0.06 (-1.43%)

03/08/16
JEFF
03/08/16
DOWNGRADE
Target $4
JEFF
Hold
Celldex downgraded to Hold with $4 target at Jefferies
Jefferies analyst Biren Amin last night downgraded Celldex Therapeutics to Hold from Buy and cut his price target for the shares to $4 from $31 following yesterday's Phase 3 trial failure of Rintega.
03/08/16
BMUR
03/08/16
NO CHANGE
Target $24
BMUR
Buy
Celldex valuation inexpensive ahead of catalysts, says Brean Capital
Brean Capital noted they removed Rintega from their Celldex model before the company announced they would discontinue their Phase 3 trial. The firm sees several upcoming catalysts in the second half of the year and believes shares can be valued substantially higher than the present value. Brean Capital reiterated its Buy rating and $24 price target on Celldex shares.
03/08/16
COWN
03/08/16
NO CHANGE
Target $12
COWN
Outperform
Celldex shares oversold, says Cowen
Cowen said it was extremely disappointing that the ACT lV pivotal study for Rintega would be stopped, driven by significant performance of the control arm. The firm believes Celldex shares are oversold and the remaining pipeline is undervalued. Cowen lowered its price target to $12 from $28 on Celldex shares and maintained its Outperform rating on the stock.
10/04/16
BMUR
10/04/16
INITIATION
Target $16
BMUR
Buy
Celldex assumed with a Buy at Brean Capital
Brean Capital analyst Jason Wittes assumed coverage of Celldex Therapeutics with a Buy rating and $16 price target.

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HUM

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SAP

SAP

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FCAU

Fiat Chrysler

$10.54

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Baker Hughes

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SYBT

S.Y. Bancorp

$42.30

0.85 (2.05%)

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CBOE

CBOE Holdings

$84.16

0.32 (0.38%)

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FCAU

Fiat Chrysler

$10.54

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TSS

TSYS

$54.31

0.5 (0.93%)

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ERJ

Embraer

$19.45

-0.3083 (-1.56%)

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Periodicals
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SLGN

Silgan Holdings

$60.10

0.24 (0.40%)

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SAH

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SLGN

Silgan Holdings

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IMAX

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AEL

American Equity

$24.63

0.53 (2.20%)

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EADSY

Airbus

$20.22

0.2 (1.00%)

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SLGN

Silgan Holdings

$60.10

0.24 (0.40%)

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Earnings
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TROW

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