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BMY

Bristol-Myers

$55.43

0.38 (0.69%)

17:33
10/09/16
10/09
17:33
10/09/16
17:33

Bristol-Myers reports data from CheckMate-016 kidney cancer study

Bristol-Myers Squibb announced updated results from the Phase 1 CheckMate -016 trial, which evaluated the safety and tolerability of Opdivo at different doses as part of a regimen with Yervoy, sunitinib or pazopanib in previously treated and treatment-naive patients with metastatic renal cell carcinoma. These updated results include findings for the Opdivo and Yervoy combinations with approximately two years of follow-up, which showed the overall response rate was 40.4% in both arms. Of the 38 responders in both treatment arms, 39.5% had an ongoing response, with a median duration of response of 20.4 months in the Opdivo 3 mg/kg plus Yervoy 1 mg/kg arm and 19.7 months in the Opdivo 1 mg/kg plus Yervoy 3 mg/kg arm. The overall survival rate at 12 months was 81% and 85% for Opdivo 3 mg/kg plus Yervoy 1 mg/kg arm and Opdivo 1 mg/kg plus Yervoy 3 mg/kg arm, respectively, and at 24 months was 67% and 70%, respectively. There were fewer Grade 3/4 treatment-related adverse events reported in the Opdivo 3 mg/kg plus Yervoy 1 mg/kg arm -- 38.3% -- than with Opdivo 1 mg/kg plus Yervoy 3 mg/kg arm -- 61.7%. Discontinuations due to treatment-related AEs included five and 13 patients in the Opdivo 3 mg/kg and Yervoy 1 mg/kg and Opdivo 1 mg/kg and Yervoy 3 mg/kg arms, respectively. Based on these results, further development of the Opdivo 1 mg/kg and Yervoy 3 mg/kg regimen was not pursued.

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    Nov

BMY Bristol-Myers
$55.43

0.38 (0.69%)

09/12/16
JEFF
09/12/16
NO CHANGE
Target $57
JEFF
Hold
Jefferies cuts Bristol-Myers price target, upgrades AstraZeneca
Jefferies analyst Jeffrey Holford lowered his price target for Bristol-Myers Squibb (BMY) to $57 from $69 saying the stock is positioned for a "rough mid term ride." The analyst sees a "difficult catalyst" set for Bristol shares with "numerous" upcoming competitor read-outs in non-small cell lung cancer. The market could see worse than expected data from Bristol's CM-026 and CM-568 studies as well as better than expected data from AstraZeneca's (AZN) MYSTIC study and Roche's (RHHBY) Chemo-IO studies in the first half of 2017, Holford tells investors in a research note. He keeps a Hold rating on Bristol and upgraded this morning AstraZeneca to Buy from Hold. Holford prefers Astra for its immunology exposure.
09/20/16
SBSH
09/20/16
NO CHANGE
Target $70
SBSH
Buy
Bristol-Myers price target lowered to $70 from $75 at Citi
In a research note titled "Brace Yourself. Attractive Valuation but No Near-Term Respite.," Citi analyst Andrew Baum lowered his price target for shares of Bristol-Myers Squibb to $70 from $75. The analyst lowered his earnings forecasts by up to 8% to reflect the "limited supportive data" in the non-small cell lung cancer indication. Baum keeps a Buy rating on the shares as he views the valuation as attractive. He points out, however, the near-term news-flow is likely to be negative.
09/27/16
PIPR
09/27/16
NO CHANGE
Target $62
PIPR
Neutral
Bristol-Myers price target lowered to $62 from $65 at Piper Jaffray
Piper Jaffray analyst Richard Purkiss lowered his price target for Bristol-Myers Squibb (BMY) to $62 saying he sees the company ceding Opdivo's early-mover advantage in lung cancer to competitors. The analyst expects to see details from Roche's (RHHBY) positive OAK trial of Tecentriq vs. docetaxel in non-small cell lung cancer at the upcoming ESMO meeting. Purkiss also expects to see details from Merck's (MRK) positive KEYNOTE-024 trial of Keytruda. The analyst lowered his post-2016 Opdivo forecasts and reiterates a Neutral rating on Bristol shares.
09/28/16
ROTH
09/28/16
NO CHANGE
Target $23
ROTH
Buy
Nektar price target raised to $23 from $19 at Roth Capital
Roth Capital analyst Michael Higgins raised his price target for Nektar (NKTR) to $23 from $19 after the company and Bristol-Myers (BMY) announced a clinical collaboration to evaluate the combination of the latter's anti-PD-1 antibody, Opdivo, with NKTR-214. The analyst reiterates a Buy rating on Nektar's shares.

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VNCE

Vince Holding

$4.55

0.35 (8.33%)

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NWBO

Northwest Biotherapeutics

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0.0227 (4.33%)

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AAPL

Apple

$111.03

1.08 (0.98%)

, MSFT

Microsoft

$61.37

1.42 (2.37%)

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$111.03

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MSFT

Microsoft

$61.37

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ATKR

Atkore

$19.71

-0.11 (-0.55%)

19:59
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Syndicate
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  • 08

    Dec

BPMC

Blueprint Medicines

$26.20

-2.23 (-7.84%)

19:58
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19:58
Syndicate
Blueprint Medicines 5M share Secondary priced at $25.00 »

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  • 08

    Dec

LULU

lululemon

$59.84

2.6 (4.54%)

19:50
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lululemon CFO says early Q4 trends strengthened into December »

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LULU

lululemon

$59.84

2.6 (4.54%)

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lululemon CEO highlights Q3 gross margin, reports 11% comp growth in pants »

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CVX

Chevron

$114.44

1.68 (1.49%)

19:20
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Chevron announces $19.8B capital, exploratory budget for 2017 »

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  • 13

    Dec

X

U.S. Steel

$37.49

1.54 (4.28%)

18:49
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18:49
Periodicals
U.S. Steel CEO: Company may bring back 10,000 U.S. jobs, CNBC says »

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VNDA

Vanda

$15.40

-0.6 (-3.75%)

18:47
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Vanda settles Fanapt patent litigation with Apotex »

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AE

Adams Resources

$42.31

-0.68 (-1.58%)

, SWN

Southwestern Energy

$12.37

-0.08 (-0.64%)

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Hot Stocks
Adams Resources appoints Josh Anders as CFO »

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AE

Adams Resources

$42.31

-0.68 (-1.58%)

SWN

Southwestern Energy

$12.37

-0.08 (-0.64%)

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EZPW

EZCORP

$11.80

0.05 (0.43%)

18:42
12/07/16
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Earnings
EZCORP reports Q4 EPS with items (31c), may not compare to consensus 6c »

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  • 08

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RICE

Rice Energy

$24.59

-0.16 (-0.65%)

18:33
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Initiation
Rice Energy initiated  »

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AMZN

Amazon.com

$770.42

5.7 (0.75%)

18:30
12/07/16
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Periodicals
Amazon spokesperson denies 2,000 grocery stores report, CNET says »

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ICON

Iconix Brand

$9.26

0.14 (1.54%)

18:23
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Iconix Brand reports employment termination of Chief Strategy Officer Blumberg »

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PBYI

Puma Biotechnology

$39.80

-2 (-4.78%)

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Puma Biotechnology 'pleased' to complete biomarker analysis of neratinib »

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FTK

Flotek

$11.10

-2.01 (-15.33%)

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Flotek: Reviewing FourWorld Capital short report, remain confident in product »

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PBYI

Puma Biotechnology

$39.80

-2 (-4.78%)

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Puma Biotechnology 'pleased' with preliminary neratinib activity »

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PNM

PNM Resources

$32.05

0.45 (1.42%)

18:09
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PNM Resources requests an electric rate increase of $99M in New Mexico »

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  • 14

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BK

BNY Mellon

$48.55

0.56 (1.17%)

18:03
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TLRD

Tailored Brands

$18.93

0.62 (3.39%)

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  • 08

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FLXS

Flexsteel Industries

$59.12

2.92 (5.20%)

, UNH

UnitedHealth

$159.40

2.08 (1.32%)

17:50
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FLXS

Flexsteel Industries

$59.12

2.92 (5.20%)

UNH

UnitedHealth

$159.40

2.08 (1.32%)

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NKE

Nike

$52.10

1.53 (3.03%)

, UA

Under Armour

$27.03

1.62 (6.38%)

17:49
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Periodicals
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NKE

Nike

$52.10

1.53 (3.03%)

UA

Under Armour

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ADDYY

adidas

$76.96

1.225 (1.62%)

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  • 20

    Dec

T

AT&T

$40.45

1.1 (2.80%)

17:45
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17:45
Conference/Events
AT&T management to meet with Jefferies »

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