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EXEL

Exelixis

$12.95

-0.23 (-1.75%)

, PFE

Pfizer

$33.68

0.12 (0.36%)

14:42
10/10/16
10/10
14:42
10/10/16
14:42

Exelixis briefly crashes, recovers after cancer expert doubts latests data

Exelixis (EXEL) dipped Monday after the official Twitter account of the European Society for Medical Oncology, which is holding a closely-watched medical conference, tweeted a statement by a cancer research expert that a Phase 3 trial is needed to confirm the company's Phase 2 data on cabozantinib, which were presented this morning. CABO RESULTS: Early this morning, Exelixis reported detailed results of its Phase 2 "CABOSUN" trial of cabozantinib in renal cell carcinoma, a type of kidney cancer. The drug demonstrated a median delay in disease progression of 8.2 months as compared to 5.6 months for Pfizer's (PFE) sunitinib, the competing treatment in the study. Forty-six percent of cabozantinib patients experienced tumor shrinkage versus 18% of sunitinib patients, and the drug achieved a median patient survival time of 30.3 months relative to sunitinib's 21.8 months. ESCUDIER SAYS CONFIRMATION NEEDED: The Twitter account of the European Society for Medical Oncology, which is relaying comments made by researchers and opinion leaders at the ongoing ESMO 2016 conference, tweeted a statement from Bernard Escudier that "a Phase 3 trial is warranted to confirm the CABOSUN results." Escudier is a well-placed member of the Gustave Roussy cancer research institute in France and has served as lead researcher in previous studies of cabozantinib. PRICE ACTION: Shares of Exelixis briefly crashed roughly 11% to $11.53 shortly after ESMO's tweet, but have since recovered and are trading near $12.91 per share. Reference Link

EXEL

Exelixis

$12.95

-0.23 (-1.75%)

PFE

Pfizer

$33.68

0.12 (0.36%)

  • 10

    Oct

  • 10

    Oct

  • 01

    Nov

EXEL Exelixis
$12.95

-0.23 (-1.75%)

10/10/16
LEER
10/10/16
NO CHANGE
LEER
Outperform
Leerink says ESMO raises confidence in potential label expansions at Exelixis
Following several oral and poster presentations this weekend at the ESMO cancer meeting, Leerink analyst Michael Schmidt said he has greater confidence regarding several potential label expansion opportunities for Exelixis' two products, Cabometyx and Cotellic. Cabometyx is "very well positioned" to capture significant market share and consensus expectations for Cotellic are only modest, believes Schmidt, who keeps an Outperform rating on Exelixis shares.
10/10/16
PIPR
10/10/16
UPGRADE
PIPR
Overweight
Exelixis upgraded to Overweight from Neutral at Piper Jaffray
10/10/16
PIPR
10/10/16
UPGRADE
Target $21
PIPR
Overweight
Exelixis upgraded to Overweight after trial success at Piper Jaffray
Piper Jaffray analyst Edward Tenthoff upgraded Exelixis to Overweight from Neutral after the company reported Phase II CABOSUN data in 157 front-line metastatic Renal Cell Carcinoma patients. The data are "good enough" to file a supplemental new drug application and could drive off-label front-line RCC use, Tenthoff tells investors in a research note. The analyst raised his price target for the shares to $21 from $8.
10/10/16
10/10/16
UPGRADE

On The Fly: Top five analyst upgrades
Catch up on today's top five analyst upgrades with this list compiled by The Fly: 1. Mylan (MYL) upgraded to Strong Buy from Market Perform at Raymond James with Elliot WIlbur saying the Department of Justice settlement over EpiPen rebates eliminates a significant overhang on shares enabling the focus to be back on fundamentals. 2. Under Armour (UA) upgraded to Outperform from Market Perform at Wells Fargo with analyst Tom Nikic saying "noise" from the Sports Authority's bankruptcy is fading while distribution expansion could lead to sales re-acceleration over the next 12-18 months. 3. Deere (DE) and AGCO (AGCO) were upgraded to Outperform from Market Perform at Wells Fargo. 4. Dow Chemical (DOW) upgraded to Buy from Neutral at UBS with analyst John Roberts saying the merger with DuPont (DD) could gain regulatory approval and that the stock is "now too cheap to ignore." 5. Exelixis (EXEL) upgraded to Overweight from Neutral at Piper Jaffray with analyst Edward Tenthoff saying the data are "good enough" to file a supplemental new drug application and could drive off-label front-line RCC use. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
PFE Pfizer
$33.68

0.12 (0.36%)

08/23/16
PIPR
08/23/16
NO CHANGE
PIPR
Pfizer acquisition 'a good fit strategically,' says Piper Jaffray
After Pfizer (PFE) agreed to buy Medivation (MDVN), Piper Jaffray analyst Richard Purkiss says that Pfizer has obtained Xtandi, "a blockbuster prostate cancer treatment," and "a close-to-market and late-stage pipeline." The analyst thinks that Xtandi's expansion to use in adjuvant prostate cancer could increase its sales by 65%-70%. He keeps a $54 price target and Overweight rating on Pfizer.
08/23/16
RHCO
08/23/16
DOWNGRADE
RHCO
Neutral
Medivation downgraded to Neutral from Buy at SunTrust
Medivation (MDVN) has agreed to be acquired by Pfizer (PFE) for $81.50 per share.
09/14/16
BMOC
09/14/16
NO CHANGE
BMOC
Pfizer should exceed fiscal 2016 guidance, says BMO Capital
BMO Capital analyst Alex Arfaei says that Pfizer should exceed its fiscal 2016 guidance. The analyst says that Medivation, which Pfizer agreed to acquire, gives Pfizer another growth driver. Additionally, Pfizer has a number of other "high margin specialty drugs," according to the analyst. He says that the stock's dividend yield is "attractive," and he keeps a $40 price target and Outperform rating on the shares.
10/07/16
ROTH
10/07/16
NO CHANGE
Target $160
ROTH
Buy
ICU Medical price target raised to $160 from $132 at Roth Capital
Roth Capital analyst Chris Lewis raised his price target for ICU Medical (ICUI) to $160 from $132 after the company announced an agreement to acquire Hospira Infusion Systems from Pfizer (PFE) for $1B. The analyst is overall positive on the deal as it removes the long-standing customer concentration overhang and grows ICU Medical into a legitimate pure-play infusion therapy company with a complete product portfolio. The company also preannounced Q3 preliminary results above expectations, he notes. Lewis reiterates a Buy rating on ICU Medical's shares.

TODAY'S FREE FLY STORIES

AVA

Avista

$51.40

0.1 (0.19%)

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BMWYY

BMW

$34.00

0.083 (0.24%)

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Periodicals
BMW to build new 8 series in Dingolfing from 2018, Reuters reports »

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CSCO

Cisco

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0.67 (2.05%)

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BMY

Bristol-Myers

$63.36

0.03 (0.05%)

18:12
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INSE

Inspired Entertainment

$13.60

0.3 (2.26%)

17:38
09/22/17
09/22
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17:38
Hot Stocks
Inspired Entertainment COO Wilson leaving by reason of redundancy »

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MNOV

MediciNova

$6.18

0.3 (5.10%)

17:30
09/22/17
09/22
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17:30
Syndicate
Breaking Syndicate news story on MediciNova »

MediciNova files $200M…

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ISRG

Intuitive Surgical

$1,031.52

1.31 (0.13%)

17:25
09/22/17
09/22
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17:25
Conference/Events
Intuitive Surgical to host special shareholder meeting »

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GD

General Dynamics

$205.41

-0.31 (-0.15%)

17:21
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General Dynamics Electric Boat awarded $341.2M government contract modification »

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CHRS

Coherus Biosciences

$12.85

0.3 (2.39%)

17:19
09/22/17
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17:19
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17:19
Syndicate
Breaking Syndicate news story on Coherus Biosciences »

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FIBK

First Interstate

$36.90

0.3 (0.82%)

17:18
09/22/17
09/22
17:18
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17:18
Syndicate
First Interstate files to sell $250M of Class A common stock »

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NRCIA

National Research, also tag NRCIB

$37.45

0.55 (1.49%)

, NRCIB

National Research, also tag NRCIA

$54.30

0.31 (0.57%)

17:08
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17:08
Hot Stocks
National Research launches metric to measure healthcare consumer loyalty »

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NRCIA

National Research, also tag NRCIB

$37.45

0.55 (1.49%)

NRCIB

National Research, also tag NRCIA

$54.30

0.31 (0.57%)

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CC

Chemours

$51.79

-0.16 (-0.31%)

, HON

Honeywell

$141.75

0.89 (0.63%)

16:58
09/22/17
09/22
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16:58
Hot Stocks
Chemours files appeal concerning SNAP 20 rule to regulate HFCs »

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CC

Chemours

$51.79

-0.16 (-0.31%)

HON

Honeywell

$141.75

0.89 (0.63%)

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AGN

Allergan

$204.65

1.99 (0.98%)

16:57
09/22/17
09/22
16:57
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16:57
Hot Stocks
Allergan receives refusal to file letter from FDA for Vraylar »

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HON

Honeywell

$141.75

0.89 (0.63%)

, CC

Chemours

$51.79

-0.16 (-0.31%)

16:51
09/22/17
09/22
16:51
09/22/17
16:51
Hot Stocks
Honeywell, Chemours seek rehearing of D.C Court decision regarding SNAP program »

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HON

Honeywell

$141.75

0.89 (0.63%)

CC

Chemours

$51.79

-0.16 (-0.31%)

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JOE

Saint Joe Co.

$18.60

0.45 (2.48%)

16:46
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Breaking Hot Stocks news story on Saint Joe Co. »

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16:40
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16:40
General news
Moody's downgrades UK's rating to Aa2, changes outlook to stable »

Moody's Investors…

A

Agilent

$65.78

-0.14 (-0.21%)

, MRK

Merck

$65.13

-0.47 (-0.72%)

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A

Agilent

$65.78

-0.14 (-0.21%)

MRK

Merck

$65.13

-0.47 (-0.72%)

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TYHT

Shineco

$3.23

-0.45 (-12.23%)

16:35
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ARCI

Appliance Recycling

$1.16

0.03 (2.65%)

16:34
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Appliance Recycling gets written notice of default »

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RNVA

Rennova Health

$0.22

0.0086 (4.07%)

16:31
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Hot Stocks
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ARCI

Appliance Recycling

$1.16

0.03 (2.65%)

16:31
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Hot Stocks
Breaking Hot Stocks news story on Appliance Recycling »

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16:30
09/22/17
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16:30
Options
Preliminary option volume of 13.9M today »

Preliminary option volume…

EKSO

Ekso Bionics

$1.28

0.14 (12.28%)

16:23
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Hot Stocks
Ekso Bionics awarded government contract »

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UNH

UnitedHealth

$193.03

-2.18 (-1.12%)

, AET

Aetna

$153.57

0.18 (0.12%)

16:22
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General news
On The Fly: Top stock stories for Friday »

The major averages…

UNH

UnitedHealth

$193.03

-2.18 (-1.12%)

AET

Aetna

$153.57

0.18 (0.12%)

ANTM

Anthem

$182.86

-0.64 (-0.35%)

CI

Cigna

$182.74

0.61 (0.33%)

AAPL

Apple

$151.89

-1.5 (-0.98%)

FSLR

First Solar

$51.41

2.65 (5.43%)

FINL

Finish Line

$9.73

0.51 (5.53%)

ASND

Ascendis Pharma

$34.24

6.5 (23.43%)

VSAR

Versartis

$2.68

-18.925 (-87.62%)

ICPT

Intercept

$61.59

-12.11 (-16.43%)

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DLR

Digital Realty

$114.51

-1.72 (-1.48%)

16:19
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Syndicate
Breaking Syndicate news story on Digital Realty »

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