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MKGAY

Merck KGaA

$36.20

0.32 (0.89%)

, PFE

Pfizer

$33.23

-0.38 (-1.13%)

12:02
10/11/16
10/11
12:02
10/11/16
12:02

Transgene collaborates with Merck KGaA, Darmstadt, Pfizer on HPV study

Transgene announced it has entered a collaboration agreement with the science and technology company Merck KGaA (MKGAY), Darmstadt, Germany, and Pfizer (PFE) under which Transgene will sponsor a Phase 1/2 study evaluating the potential of the therapeutic vaccine candidate TG4001 in combination with avelumab, an investigational fully human anti-PD-L1 IgG1 monoclonal antibody, for the treatment of human papilloma virus-positive head and neck squamous cell carcinoma, after failure of standard therapy. Philippe Archinard, Chairman and CEO of Transgene, commented: "We are pleased to enter this collaboration with Merck KGaA, Darmstadt, Germany, and Pfizer to evaluate our therapeutic vaccine TG4001 in association with avelumab. In previous clinical trials, TG4001 has demonstrated promising activity in terms of HPV viral clearance and was well tolerated. TG4001 is one of the few drugs targeting HPV-associated cancers that can be combined with an immune checkpoint blocker such as avelumab. The preclinical and clinical data that have been generated with both TG4001 and avelumab individually suggest this combination could potentially demonstrate a synergistic effect, delivering a step up in therapy for HPV-positive HNSCC patients." The combination of TG4001 and avelumab aims to target two distinct steps in the immune response to target cancer cells. This is an exclusive agreement between the parties to study the combination of these two classes of investigational agents in HPV-positive HNSCC.

MKGAY

Merck KGaA

$36.20

0.32 (0.89%)

PFE

Pfizer

$33.23

-0.38 (-1.13%)

  • 01

    Nov

MKGAY Merck KGaA
$36.20

0.32 (0.89%)

08/12/16
BREN
08/12/16
DOWNGRADE
BREN
Hold
Merck KGaA downgraded to Hold from Buy at Berenberg
PFE Pfizer
$33.23

-0.38 (-1.13%)

10/07/16
ROTH
10/07/16
NO CHANGE
Target $160
ROTH
Buy
ICU Medical price target raised to $160 from $132 at Roth Capital
Roth Capital analyst Chris Lewis raised his price target for ICU Medical (ICUI) to $160 from $132 after the company announced an agreement to acquire Hospira Infusion Systems from Pfizer (PFE) for $1B. The analyst is overall positive on the deal as it removes the long-standing customer concentration overhang and grows ICU Medical into a legitimate pure-play infusion therapy company with a complete product portfolio. The company also preannounced Q3 preliminary results above expectations, he notes. Lewis reiterates a Buy rating on ICU Medical's shares.
09/14/16
BMOC
09/14/16
NO CHANGE
BMOC
Pfizer should exceed fiscal 2016 guidance, says BMO Capital
BMO Capital analyst Alex Arfaei says that Pfizer should exceed its fiscal 2016 guidance. The analyst says that Medivation, which Pfizer agreed to acquire, gives Pfizer another growth driver. Additionally, Pfizer has a number of other "high margin specialty drugs," according to the analyst. He says that the stock's dividend yield is "attractive," and he keeps a $40 price target and Outperform rating on the shares.
08/23/16
RHCO
08/23/16
DOWNGRADE
RHCO
Neutral
Medivation downgraded to Neutral from Buy at SunTrust
Medivation (MDVN) has agreed to be acquired by Pfizer (PFE) for $81.50 per share.
08/23/16
PIPR
08/23/16
NO CHANGE
PIPR
Pfizer acquisition 'a good fit strategically,' says Piper Jaffray
After Pfizer (PFE) agreed to buy Medivation (MDVN), Piper Jaffray analyst Richard Purkiss says that Pfizer has obtained Xtandi, "a blockbuster prostate cancer treatment," and "a close-to-market and late-stage pipeline." The analyst thinks that Xtandi's expansion to use in adjuvant prostate cancer could increase its sales by 65%-70%. He keeps a $54 price target and Overweight rating on Pfizer.

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ANET

Arista Networks

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-1.35 (-1.41%)

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TKTDY

Takata Corporation

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0.05 (0.47%)

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DV

DeVry

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CSOD

Cornerstone OnDemand

$39.10

-0.11 (-0.28%)

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CVM

CEL-SCI

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-0.0014 (-1.17%)

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XOM

Exxon Mobil

$89.00

0.68 (0.77%)

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Exxon CEO Tillerson emerges as top candidate for secretary of state, WSJ says »

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FUL

H.B. Fuller

$50.36

0.05 (0.10%)

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H.B. Fuller announces restructuring, to eliminate, relocate 220 positions »

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BIIB

Biogen

$287.77

-1.77 (-0.61%)

17:53
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SNY

Sanofi

$40.40

0.63 (1.58%)

17:42
12/09/16
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Sanofi to lay off 20% of U.S. diabetes, cardiovascular staff, Bloomberg says »

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CSOD

Cornerstone OnDemand

$39.10

-0.11 (-0.28%)

17:38
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Periodicals
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TACO

Del Taco

$14.75

-0.39 (-2.58%)

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UNVR

Univar

$26.36

0.54 (2.09%)

, BXLT

Baxalta

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UNVR

Univar

$26.36

0.54 (2.09%)

BXLT

Baxalta

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PARN

Parnell

$1.42

-0.0031 (-0.22%)

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BSX

Boston Scientific

$20.81

0.2 (0.97%)

, NVRO

Nevro

$76.38

-1.88 (-2.40%)

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BSX

Boston Scientific

$20.81

0.2 (0.97%)

NVRO

Nevro

$76.38

-1.88 (-2.40%)

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  • 12

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RTN

Raytheon

$146.30

0.14 (0.10%)

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CX

CEMEX

$8.77

-0.16 (-1.79%)

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PDEX

PRO-DEX

$4.48

0.034 (0.76%)

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PFBX

Peoples Financial

$14.50

-0.5 (-3.33%)

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QUIK

QuickLogic

$0.94

-0.0163 (-1.71%)

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STRZA

Starz

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BEL

Belmond

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Breaking Syndicate news story on Belmond »

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PARN

Parnell

$1.42

-0.0031 (-0.22%)

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MS

Morgan Stanley

$43.73

0.15 (0.34%)

, SHAK

Shake Shack

$38.08

0.82 (2.20%)

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Morgan Stanley

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Shake Shack

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MS

Morgan Stanley

$43.73

0.15 (0.34%)

, LXFT

Luxoft

$54.40

-1.8 (-3.20%)

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MS

Morgan Stanley

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LXFT

Luxoft

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FUL

H.B. Fuller

$50.36

0.05 (0.10%)

16:44
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