Breaking News Instant updates and real-time market news.

ADAP

Adaptimmune

$6.56

-0.09 (-1.35%)

09:29
10/12/16
10/12
09:29
10/12/16
09:29

Adaptimmune provides update in NY-ESO SPEAR clinical study

Adaptimmune Therapeutics announced that its amended protocol using its NY-ESO SPEAR, or Specific Peptide Enhanced Affinity Receptor, T-cell therapy in ovarian cancer patients with treatment resistant or refractory metastatic ovarian cancer is now actively recruiting. To date, no objective clinical responses have been reported in the ovarian cancer patients who received NY-ESO SPEAR T-cell therapy in the initial iteration of this trial. Of note, these initial patients received a preconditioning regimen which consisted of cyclophosphamide alone, rather than including fludarabine. Data from Adaptimmune's studies of its NY-ESO SPEAR T-cell therapy in synovial sarcoma patients have indicated the importance of including fludarabine in the preconditioning regimen. The use of fludarabine appears to be required for expansion, response and persistence of transduced cells. As a result, this trial will enroll patients under a revised protocol including a pre-conditioning regimen that includes fludarabine in combination with cyclophosphamide.

ADAP Adaptimmune
$6.56

-0.09 (-1.35%)

02/25/16
02/25/16
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Boston Scientific (BSX) initiated with a Buy at SunTrust by analyst Bruce Nudell, who expects an organic growth accelerating through 2018 driven by structural heart sales and core market stabilization. 2. Kite Pharma (KITE) initiated with a Buy, with analyst Robyn Karnauskas saying that Kite's technology could be the first to market and its data in the largest blood cancer market look similar to competition. The analyst also started Juno Therapeutics (JUNO) and Adaptimmune (ADAP) with Buy ratings. 3. Insulet (PODD) initiated with a Sell at Empire by analyst Cathy Reese, who said the company has several issues with its OmniPod System that will not be remedied with planned upgrades. 4. Biogen (BIIB) initiated with a Buy at Citi. 5. Crown Castle (CCI) initiated with a Buy at SunTrust. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
08/04/16
LEER
08/04/16
NO CHANGE
LEER
Outperform
Adaptimmune partial clinical hold on planned trial 'surprising,' says Leerink
Leerink analyst Michael Schmidt sees the announced partial clinical hold on Adaptimmune's liposarcoma study as "surprising" and notes that it introduces some additional risk. However, the analyst says the news does not "fundamentally" change his investment thesis on Adaptimmune as he expects a rapid resolution. Schmidt reiterates an Outperform rating on the shares.
08/26/16
SBSH
08/26/16
NO CHANGE
SBSH
Buy
Adaptimmune partial clinical hold may be lifted within weeks, says Citi
Citi analyst Robyn Karnauskas said that after traveling with several members of Adaptimmune's management team, including its CEO and CFO, she came away feeling that their TCR platform remains in the lead despite delays. The FDA's partial clinical hold in myxoid round cell liposarcoma, or MRCLS, was not related to safety or efficacy of the product and Karnauskas sees the potential for the FDA to possibly reverse the partial clinical hold within a few weeks, she tells investors. Citi keeps a Buy rating on Adaptimmune shares.
09/30/16
RAJA
09/30/16
INITIATION
Target $16
RAJA
Outperform
Adaptimmune initiated with an Outperform at Raymond James
Raymond James analyst Reni Benjamin initiated Adaptimmune with a Buy and a $16 price target saying it is a leading player in the engineered T cell receptor therapy space, with a growing product portfolio concentrating primarily in the solid tumor market.

TODAY'S FREE FLY STORIES

WDC

Western Digital

$90.25

-0.78 (-0.86%)

11:25
06/23/17
06/23
11:25
06/23/17
11:25
Options
Western Digital call volume above normal and directionally bullish »

Bullish option flow…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

VLKAY

Volkswagen

$30.88

0.6 (1.98%)

11:22
06/23/17
06/23
11:22
06/23/17
11:22
Periodicals
VW reducing workforce at core unit more quickly than planned, Reuters says »

Volkswagen is cutting…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

PTLA

Portola Pharmaceuticals

$38.25

-1.24 (-3.14%)

11:18
06/23/17
06/23
11:18
06/23/17
11:18
Hot Stocks
Breaking Hot Stocks news story on Portola Pharmaceuticals »

Portola Pharmaceuticals…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 23

    Jun

  • 24

    Jun

$NSD

NASDAQ Market Internals

11:17
06/23/17
06/23
11:17
06/23/17
11:17
Technical Analysis
NASDAQ market internals summary »

Volume is average for…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

$NYE

NYSE Market Internals

11:16
06/23/17
06/23
11:16
06/23/17
11:16
Technical Analysis
NYSE market internals summary »

Volume is below average…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

VALE

Vale

$8.22

0.12 (1.48%)

11:10
06/23/17
06/23
11:10
06/23/17
11:10
Options
10K VALE Jan 10 calls trade at 40c on ISE »

10K VALE Jan 10 calls…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

NURO

NeuroMetrix

$2.89

0.056 (1.98%)

11:08
06/23/17
06/23
11:08
06/23/17
11:08
Hot Stocks
NeuroMetrix provides update on Quell wearable pain relief clinical program »

NeuroMetrix provided an…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

CAT

Caterpillar

$103.76

-0.08 (-0.08%)

11:08
06/23/17
06/23
11:08
06/23/17
11:08
Hot Stocks
As bar gets raised Deutsche Bank gets less bullish on Caterpillar »

Deutsche Bank downgraded…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

HZNP

Horizon Pharma

$11.87

0.44 (3.85%)

11:04
06/23/17
06/23
11:04
06/23/17
11:04
Earnings
Horizon Pharma now sees FY17 net sales $985M-$1.02B, consensus $990.53M »

In May, Horizon lowered…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

HZNP

Horizon Pharma

$11.87

0.44 (3.85%)

11:02
06/23/17
06/23
11:02
06/23/17
11:02
Hot Stocks
Horizon Pharma completes sale of European marketing rights for Procysbi »

Horizon Pharma announced…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

UUP

PowerShares DB US Dollar Index Up

$25.14

-0.09 (-0.36%)

11:00
06/23/17
06/23
11:00
06/23/17
11:00
Options
Large spread in UPS as shares deliver gains »

Large spread in UPS as…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

11:00
06/23/17
06/23
11:00
06/23/17
11:00
General news
Breaking General news story  »

St. Louis Federal Reserve…

10:55
06/23/17
06/23
10:55
06/23/17
10:55
General news
Euro$ interest rate futures are marginally lower »

Euro$ interest rate…

NVO

Novo Nordisk

$44.13

0.46 (1.05%)

10:52
06/23/17
06/23
10:52
06/23/17
10:52
Hot Stocks
Novo Nordisk reports up to 13.8% weight loss in people receiving semaglutide »

Novo Nordisk announced…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

UPS

UPS

$110.54

1.469 (1.35%)

10:45
06/23/17
06/23
10:45
06/23/17
10:45
Options
UPS call volume above normal and directionally bullish »

Bullish option flow…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 07

    Jul

WMGI

Wright Medical

$26.99

0.11 (0.41%)

10:45
06/23/17
06/23
10:45
06/23/17
10:45
Conference/Events
Wright Medical has a conference call hosted by JPMorgan »

JPMorgan Analyst Hanover…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 23

    Jun

  • 26

    Jun

  • 28

    Jun

  • 03

    Jul

WDC

Western Digital

$90.25

-0.78 (-0.86%)

10:40
06/23/17
06/23
10:40
06/23/17
10:40
Technical Analysis
Technical View: Western Digital trades higher as Toshiba indicates open to talks »

The stock was last up…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

SNCR

Synchronoss

$12.18

1.53 (14.37%)

10:31
06/23/17
06/23
10:31
06/23/17
10:31
Hot Stocks
Synchronoss confirms receipt of Siris Capital indication of interest »

Synchronoss Technologies…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

TGT

Target

$50.81

0.175 (0.35%)

10:31
06/23/17
06/23
10:31
06/23/17
10:31
Periodicals
Target starts removing all Hampton Creek products from stores, Bloomberg reports »

Target is voluntarily…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

10:30
06/23/17
06/23
10:30
06/23/17
10:30
General news
The 2.9% May U.S. new home sales rise »

The 2.9% May U.S. new…

YY

YY

$58.32

-0.66 (-1.12%)

10:28
06/23/17
06/23
10:28
06/23/17
10:28
Conference/Events
YY management to meet with Jefferies »

Meeting to be held in New…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Jun

SYY

Sysco

$50.78

-1.9958 (-3.78%)

, USFD

US Foods

$26.33

-1.275 (-4.62%)

10:27
06/23/17
06/23
10:27
06/23/17
10:27
Hot Stocks
JPMorgan sees food distributors facing competition from Amazon »

Noting that Amazon's…

SYY

Sysco

$50.78

-1.9958 (-3.78%)

USFD

US Foods

$26.33

-1.275 (-4.62%)

PFGC

Performance Food Group

$26.00

-1.25 (-4.59%)

AMZN

Amazon.com

$1,001.30

-0.93 (-0.09%)

WFM

Whole Foods

$43.20

-0.06 (-0.14%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 28

    Jun

ALGN

Align Technology

$149.69

0.27 (0.18%)

10:25
06/23/17
06/23
10:25
06/23/17
10:25
Conference/Events
Stifel medical technology analysts hold an analyst/industry conference call »

Research Team discusses…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 23

    Jun

  • 26

    Jun

TM

Toyota

$105.10

-0.39 (-0.37%)

10:24
06/23/17
06/23
10:24
06/23/17
10:24
Conference/Events
Toyota management to meet with Needham »

Meeting to be held in San…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Jun

AVEO

AVEO Oncology

$0.73

0.0281 (4.02%)

10:23
06/23/17
06/23
10:23
06/23/17
10:23
Recommendations
AVEO Oncology analyst commentary  »

Piper ups AVEO Oncology…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Get Full Fly Access

Breaking market intelligence sent straight to you
Our team of experts analyze every news story and filter out the noise to deliver real-time market moving news.
Up-to-date information on important industry events
Get real-time updates on events that are moving the market—from conferences and calls to syndicate announcements.
News focused on the companies in your portfolio
Create up to 12 portfolios with 150 stocks each, and see how active they are in market news.