| 2016-10-13 07:06:48|
OCUL, REGN 07:06 10/13 10/13/16
Ocular Therapeutix outlines strategy for sustained release intravitreal depots
Ocular Therapeutix (OCUL) provided an update on the company's development strategy for its sustained release intravitreal depot technology for the treatment of serious retinal diseases. The company is currently developing proprietary sustained-release hydrogel-based drug delivery depots for intravitreal injection that can be formulated with both small and large molecule pharmaceuticals, such as tyrosine kinase inhibitors and protein-based anti-vascular endothelial growth factors respectively, with the goal of delivering sustained and therapeutic levels of drugs to targeted ocular tissues. The goal of the company's intravitreal depot dual development program is to reduce the frequency of injections that are currently the standard of care for the treatment of wet AMD, DME and other retinal diseases. Accordingly, Ocular Therapeutix also announced today that it has entered into a strategic collaboration, option and license agreement with Regeneron Pharmaceuticals (REGN) for the development of a sustained release formulation of Regeneron's VEGF trap, aflibercept, for the treatment of wet age-related macular degeneration and other serious retinal diseases. Regeneron's aflibercept is currently approved by the U.S. FDA for certain indications under the brand name EYLEA. Per the agreement, Ocular Therapeutix retains all rights to develop its sustained-release hydrogel-based drug delivery platform with all other non-VEGF targeting compounds as well as with small molecule pharmaceuticals, including TKIs, for other retinal diseases.