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OGXI

OncoGenex

$0.45

0.015 (3.46%)

07:31
10/13/16
10/13
07:31
10/13/16
07:31

OncoGenex says Phase 3 ENSPIRIT trial did not meet primary endpoint

OncoGenex Pharmaceuticals announced results from the final analysis of the Phase 3 ENSPIRIT trial of custirsen in patients whose non-small cell lung cancer has progressed following initial treatments. The trial did not meet the primary endpoint of demonstrating a statistically significant improvement in overall survival for patients treated with custirsen in combination with docetaxel compared to docetaxel alone. The median overall survival for the custirsen arm was 9.0 months versus 7.9 months for the control arm with a hazard ratio of 0.915 (one-sided p=0.178). Safety results were consistent with those observed in previous trials of custirsen in combination with chemotherapy. "Following the negative results of previous custirsen trials, an early final analysis of the ENSPIRIT trial was conducted in an effort to conserve capital and extend our cash runway," said Scott Cormack, President and CEO of OncoGenex. "We will continue to take appropriate steps to realize the most value for our shareholders once we receive the results of our apatorsen Phase 2 Borealis-2 bladder cancer trial which are expected by the end of October."

OGXI OncoGenex
$0.45

0.015 (3.46%)

12/02/15
STFL
12/02/15
DOWNGRADE
STFL
Hold
OncoGenex downgraded to Hold from Buy at Stifel
12/02/15
STFL
12/02/15
DOWNGRADE
STFL
Hold
OncoGenex downgraded on data miss at Stifel
As noted earlier, Stifel downgraded OncoGenex to Hold from Buy. The firm downgraded the stock after the company's AFFINITY drug combination failed to achieve a statistical threshold for overall survival in a subpopulation of metastatic castrate-resistant prostate cancer patients with poor-prognostic risk factors. The firm thinks that the drug combination's visibility is currently minimal.
12/02/15
12/02/15
DOWNGRADE

On The Fly: Analyst Downgrade Summary
Today's noteworthy downgrades include: ARM Holdings (ARMH) downgraded on royalty outlook at JMP Securities... ArcBest (ARCB) downgraded to Underperform from Neutral at BofA/Merrill... ArcelorMittal (MT) downgraded to Neutral from Buy at Citi... Banco Bilbao (BBVA) downgraded to Underperform from Neutral at BofA/Merrill... Bayer (BAYRY) downgraded to Neutral from Buy at Citi... Belgacom (BGAOY) downgraded to Sell from Neutral at Citi... C.H. Robinson (CHRW) downgraded to Underperform from Neutral at BofA/Merrill... Cepheid (CPHD) downgraded to Market Perform from Outperform at Wells Fargo... Eagle Bancorp (EGBN) downgraded to Market Perform from Outperform at Keefe Bruyette... Franklin Street (FSP) downgraded to Underweight from Equalweight at Capital One... Golar LNG (GLNG) downgraded to Neutral from Buy at BofA/Merrill... Grifols (GRFS) downgraded to Hold from Buy at HSBC... ITC Holdings (ITC) downgraded to Hold from Buy at Argus... Johnson Controls (JCI) downgraded to Market Perform from Outperform at William Blair... Knight Transportation (KNX) downgraded to Neutral from Buy at BofA/Merrill... Liberty Property (LPT) downgraded to Equalweight from Overweight at Capital One... Mattson (MTSN) downgraded to Hold from Buy at Needham... Nike (NKE) downgraded to Buy from Conviction Buy at Goldman... Old Dominion (ODFL) downgraded to Neutral from Buy at BofA/Merrill... OncoGenex (OGXI) downgraded on data miss at Stifel... STAG Industrial (STAG) downgraded to Equalweight from Overweight at Capital One... SunCoke Energy (SXC) downgraded to Neutral from Buy at Clarksons Platou... Swift Energy (SFY) downgraded to Underperform from Market Perform at Wells Fargo... Swift Transport (SWFT) downgraded to Neutral from Buy at BofA/Merrill... TerraForm Global (GLBL) downgraded to Sell from Neutral at Goldman... Thor Industries (THO) downgraded to Hold from Buy at Gabelli... Werner (WERN) downgraded to Underperform from Neutral at BofA/Merrill.

TODAY'S FREE FLY STORIES

PGNX

Progenics

$10.62

0.08 (0.76%)

, CLMS

Calamos

$8.24

-0.03 (-0.36%)

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$8.24

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SFLY

Shutterfly

$48.06

0.66 (1.39%)

, VASC

Vascular Solutions

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Shutterfly to replace Vascular Solutions in S&P 600 as of 2/20 close »

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AXP

American Express

$79.71

0.2 (0.25%)

, MAT

Mattel

$26.10

0.43 (1.68%)

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Toy Industry Association to hold fair »

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MAT

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NICE

NICE Systems

$69.04

-1.27 (-1.81%)

04:55
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Conference/Events
NICE Systems management to meet with Oppenheimer »

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KHC

Kraft Heinz

$96.65

9.37 (10.74%)

, UN

Unilever; also tag UL

$48.79

6.47 (15.29%)

19:22
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02/19
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Hot Stocks
Kraft Heinz withdraws proposal to acquire Unilever »

Unilever (UN, UL) and…

KHC

Kraft Heinz

$96.65

9.37 (10.74%)

UN

Unilever; also tag UL

$48.79

6.47 (15.29%)

UL

Unilever; also tag UN

$48.53

5.96 (14.00%)

BRK.A

Berkshire Hathaway

$252,838.00

1338 (0.53%)

BRK.B

Berkshire Hathaway

$168.57

0.83 (0.49%)

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MNTA

Momenta

13:43
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Momenta to hold a conference call »

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RSPP

RSP Permian

$42.28

-0.54 (-1.26%)

12:48
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AXP

American Express

$79.71

0.2 (0.25%)

, MAT

Mattel

$26.10

0.43 (1.68%)

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AXP

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$79.71

0.2 (0.25%)

MAT

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$26.10

0.43 (1.68%)

HAS

Hasbro

$98.50

0.86 (0.88%)

COST

Costco

$175.86

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AMZN

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QUNR

Qunar

$30.88

-0.14 (-0.45%)

15:28
02/18/17
02/18
15:28
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Conference/Events
Qunar to host special shareholder meeting »

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REG

Regency Centers

$69.75

0.23 (0.33%)

, EQY

Equity One

$31.29

0.16 (0.51%)

15:21
02/18/17
02/18
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Equity One to host special shareholder meeting »

Special Shareholder…

REG

Regency Centers

$69.75

0.23 (0.33%)

EQY

Equity One

$31.29

0.16 (0.51%)

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EQY

Equity One

$31.29

0.16 (0.51%)

, REG

Regency Centers

$69.75

0.23 (0.33%)

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EQY

Equity One

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0.16 (0.51%)

REG

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$69.75

0.23 (0.33%)

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WIN

Windstream

$7.05

0.03 (0.43%)

, ELNK

EarthLink

$5.63

-0.01 (-0.18%)

15:12
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WIN

Windstream

$7.05

0.03 (0.43%)

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$5.63

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ELNK

EarthLink

$5.63

-0.01 (-0.18%)

, WIN

Windstream

$7.05

0.03 (0.43%)

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Windstream to host special shareholder meeting »

Virtual Special…

ELNK

EarthLink

$5.63

-0.01 (-0.18%)

WIN

Windstream

$7.05

0.03 (0.43%)

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HNR

Harvest Natural

14:50
02/18/17
02/18
14:50
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Harvest Natural to host special shareholder meeting »

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PH

Parker-Hannifin

$153.89

-0.52 (-0.34%)

, CLC

Clarcor

14:30
02/18/17
02/18
14:30
02/18/17
14:30
Conference/Events
Clarcor to host special shareholder meeting »

Special Shareholder…

PH

Parker-Hannifin

$153.89

-0.52 (-0.34%)

CLC

Clarcor

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  • 23

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AZN

AstraZeneca

$29.16

0.4 (1.39%)

, BAYRY

Bayer

$113.29

0.05 (0.04%)

04:55
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American Society of Clinical Oncology to hold a symposium »

2017 Genitourinary…

AZN

AstraZeneca

$29.16

0.4 (1.39%)

BAYRY

Bayer

$113.29

0.05 (0.04%)

BMY

Bristol-Myers

$54.59

0.31 (0.57%)

ESALY

Eisai

$54.40

0.205 (0.38%)

EXEL

Exelixis

$23.12

0.47 (2.08%)

GHDX

Genomic Health

$29.11

0.61 (2.14%)

MRK

Merck

$65.39

0.13 (0.20%)

MYGN

Myriad Genetics

$18.62

1.35 (7.82%)

NVS

Novartis

$77.20

0.47 (0.61%)

OPK

OPKO Health

$8.81

0.06 (0.69%)

PFE

Pfizer

PGNX

Progenics

$10.62

0.08 (0.76%)

SNY

Sanofi

$43.16

-0.38 (-0.87%)

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MDT

Medtronic

$78.88

0.89 (1.14%)

, NVO

Novo Nordisk

$35.46

0.02 (0.06%)

04:55
02/18/17
02/18
04:55
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04:55
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Kenes International Organizers to hold a conference »

10th International…

MDT

Medtronic

$78.88

0.89 (1.14%)

NVO

Novo Nordisk

$35.46

0.02 (0.06%)

RHHBY

Roche

$30.53

0.02 (0.07%)

ABT

Abbott

$44.69

0.49 (1.11%)

SNY

Sanofi

$43.16

-0.38 (-0.87%)

LLY

Eli Lilly

$80.39

0.35 (0.44%)

DXCM

Dexcom

$81.89

0.5 (0.61%)

JNJ

Johnson & Johnson

$118.86

0.78 (0.66%)

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AXP

American Express

$79.71

0.2 (0.25%)

, MAT

Mattel

$26.10

0.43 (1.68%)

04:55
02/18/17
02/18
04:55
02/18/17
04:55
Conference/Events
Toy Industry Association to hold fair »

International Toy Fair…

AXP

American Express

$79.71

0.2 (0.25%)

MAT

Mattel

$26.10

0.43 (1.68%)

HAS

Hasbro

$98.50

0.86 (0.88%)

COST

Costco

$175.86

0.11 (0.06%)

AMZN

Amazon.com

$845.07

0.93 (0.11%)

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PKY

Parkway

$21.58

0.08 (0.37%)

18:20
02/17/17
02/17
18:20
02/17/17
18:20
Hot Stocks
Parkway to sell 49% interest in Houston Greenway portfolio for $512.1M »

Parkway announced that it…

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  • 24

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VIA

Viacom

$47.00

-0.2 (-0.42%)

, VIAB

Viacom

$43.99

-0.17 (-0.38%)

18:15
02/17/17
02/17
18:15
02/17/17
18:15
Periodicals
Paramount CEO Brad Grey to leave studio as early as next week, Reuters says »

Brad Grey, chairman and…

VIA

Viacom

$47.00

-0.2 (-0.42%)

VIAB

Viacom

$43.99

-0.17 (-0.38%)

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  • 06

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MNTA

Momenta

, PFE

Pfizer

18:03
02/17/17
02/17
18:03
02/17/17
18:03
Hot Stocks
Momenta: Sandoz partner Pfizer receives FDA warning letter »

Momenta Pharmaceuticals…

MNTA

Momenta

PFE

Pfizer

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CI

Cigna

$143.56

-1.77 (-1.22%)

, ANTM

Anthem

$160.25

-3.52 (-2.15%)

17:53
02/17/17
02/17
17:53
02/17/17
17:53
Periodicals
Cigna claims Anthem attempted to harm its business, Bloomberg says »

Cigna (CI) has accused…

CI

Cigna

$143.56

-1.77 (-1.22%)

ANTM

Anthem

$160.25

-3.52 (-2.15%)

03/08/13
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03/06/13
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SCMP

Sucampo

$11.80

0.05 (0.43%)

, NILE

Blue Nile

17:50
02/17/17
02/17
17:50
02/17/17
17:50
Hot Stocks
Sucampo to replace Blue Nile in the S&P 600 as of February 23 open »

Sucampo Pharmaceuticals…

SCMP

Sucampo

$11.80

0.05 (0.43%)

NILE

Blue Nile

03/08/13
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  • 21

    Mar

VRML

Vermillion

$1.75

0.08 (4.79%)

17:39
02/17/17
02/17
17:39
02/17/17
17:39
Hot Stocks
Jack Schuler raises stake in Vermillion to 19.6% »

As of the date hereof,…

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SITO

SITO Mobile

$2.29

0.08 (3.62%)

17:34
02/17/17
02/17
17:34
02/17/17
17:34
Hot Stocks
SITO Mobile announces Jerry Hug resigned as CEO, names O'Connell interim »

Effective February 1,…

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