Breaking News Instant updates and real-time market news.

BMRN

BioMarin

$86.87

-1.08 (-1.23%)

16:02
10/13/16
10/13
16:02
10/13/16
16:02

BioMarin BMN 270 study enrollment approved by MHRA

BioMarin Pharmaceuticals announced that the Medicines and Healthcare Products Regulatory Agency in the United Kingdom approved continued enrollment into the open-label Phase 1/2 study of BMN 270, an investigational gene therapy treatment for severe hemophilia A. BioMarin had previously announced that after enrolling the first 9 patients in the study, that dosing of patients had been suspended due to observed increases in alanine aminotransferase levels that exceeded a pre specified threshold set by the company. Following study suspension, the company reviewed safety and efficacy data on the 9 patients with the MHRA, and based on its review, the MHRA approved resumption of the study. The agency also approved the company's proposed amendments to the study, which included eliminating the requirement for prophylactic corticosteroids and increasing potential additional enrollment from up to three additional patients to up to six additional patients. BioMarin intends to resume enrollment in the Phase I/2 study before the end of 2016. Based on protocol amendments, three patients will be enrolled at a dose of 4 x 1013 vg/kg, and an additional three may be enrolled at this dose or the previously tested high dose of 6 x 1013 vg/kg. In the up to six additional patients, the requirement for prophylactic corticosteroids has been removed and the threshold for starting therapeutic corticosteroids has been increased. Safety and efficacy data from these patients will inform the Phase 2b study planned to begin in the second half of 2017. "We are pleased that MHRA has approved the resumption of enrollment of the BMN 270 study, as well as the study amendments. We believe that the amendments will allow us to optimize the design of a robust Phase 2b clinical trial, which potentially could support an accelerated approval by health authorities," said Hank Fuchs, M.D., Chief Medical Officer at BioMarin. "We are grateful to the patients who are participating in this current study, and are encouraged by the results so far for this Phase 1/2 trial."

  • 27

    Oct

  • 06

    Nov

  • 29

    Nov

  • 14

    Dec

  • 28

    Jan

  • 27

    Apr

BMRN BioMarin
$86.87

-1.08 (-1.23%)

09/19/16
RAJA
09/19/16
NO CHANGE
RAJA
Outperform
Sarepta approval opens up revenue stream for BioMarin, says Raymond James
Raymond James analyst Christopher Raymond noted that the FDA approval of Sarepta's (SRPT) eteplirsen for the treatment of exon 51 skipping amenable Duchenne's muscular dystrophy opens up an "unexpected potential revenue stream" for BioMarin (BMRN), which he said currently holds a "dominant patent position" on Exon 51 skipping therapies. The analyst, who thinks BioMarin may stand to benefit from Sarepta's news, keeps an Outperform rating on BioMarin shares.
09/21/16
09/21/16
NO CHANGE

RBC identifies top biotech takeover candidates
RBC Capital identified the following names as its top potential takeover candidates in the biotech space: ARIAD (ARIA), Spark Therapeutics (ONCE), BioMarin (BMRN), Aerie Pharmaceuticals (AERI), Intra-Cellular (ITCI), TESARO (TSRO), Incyte (INCY), Sarepta (SRPT), and Puma Biotechnology (PBYI). The firm thinks that investors are underestimating the positive impact that M&A will have on biotech stock prices.
09/21/16
LEER
09/21/16
NO CHANGE
LEER
Market Perform
Previous PTAB ruling remains overhang on Sarepta eteplirsen, says Leerink
Leerink analyst Joseph Schwartz notes that Sarepta (SRPT) has announced favorable Patent Trial and Appeal Board of the U.S. Patent and Trademark Office decisions in favor of its exon 51 and 53 composition of matter patent interference cases against BioMarin (BMRN). However, he points out that these rulings are subject to appeal and a previous ruling from the U.S. Patent Trial and Appeal Board, or PTAB, in favor of BioMarin's method of use patent remains an overhang on the commercialization of Sarepta's eteplirsen. The analyst reiterates a Market Perform rating on Sarepta's shares.
10/07/16
GSCO
10/07/16
NO CHANGE
GSCO
Smid-cap Biotech sector upgraded to Attractive from Neutral at Goldman
Goldman analyst Salveen Richter upgraded the Smid-cap biotechnology to Attractive and said he favors and companies with near-term pipeline data or regulatory events where he has conviction.Names he recommends are Buy rated BioMarin (BMRN), bluebird bio (BLUE), GW Pharma (GWPH), Incyte (INCY), Kite (KITE), and Sage (SAGE).

TODAY'S FREE FLY STORIES

FOX

21st Century Fox

$29.86

-0.07 (-0.23%)

, FOXA

21st Century Fox

$30.54

-0.02 (-0.07%)

20:36
04/30/17
04/30
20:36
04/30/17
20:36
Hot Stocks
On The Fly: Top five weekend stock stories »

Catch up on the…

FOX

21st Century Fox

$29.86

-0.07 (-0.23%)

FOXA

21st Century Fox

$30.54

-0.02 (-0.07%)

BX

Blackstone

$30.84

-0.13 (-0.42%)

TRCO

Tribune Media

$36.56

-0.28 (-0.76%)

SBGI

Sinclair Broadcast

$39.45

-0.9 (-2.23%)

TSLA

Tesla

$314.07

5.44 (1.76%)

TWTR

Twitter

$16.48

-0.13 (-0.78%)

CMCSA

Comcast

$39.19

-0.4 (-1.01%)

CMCSK

Comcast

DIS

Disney

$115.60

-0.24 (-0.21%)

CAT

Caterpillar

$102.26

-0.42 (-0.41%)

NEE

NextEra Energy

$133.56

0.04 (0.03%)

EPC

Edgewell Personal Care

$71.49

-0.14 (-0.20%)

COH

Coach

$39.39

-0.43 (-1.08%)

LITE

Lumentum

$42.75

-1.05 (-2.40%)

OCLR

Oclaro

$8.01

0.08 (1.01%)

ESRX

Express Scripts

$61.34

-0.06 (-0.10%)

CMG

Chipotle

$474.47

-7.53 (-1.56%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 02

    May

  • 02

    May

  • 02

    May

  • 03

    May

  • 03

    May

  • 04

    May

  • 08

    May

  • 09

    May

  • 10

    May

  • 18

    May

  • 30

    May

  • 06

    Jun

  • 14

    Jun

  • 15

    Jun

AWI

Armstrong World

$46.75

-0.75 (-1.58%)

, L

Loews

$46.62

-0.71 (-1.50%)

20:25
04/30/17
04/30
20:25
04/30/17
20:25
Earnings
Notable companies reporting before Monday's open »

Notable companies…

AWI

Armstrong World

$46.75

-0.75 (-1.58%)

L

Loews

$46.62

-0.71 (-1.50%)

ENSG

Ensign Group

$17.95

-1.17 (-6.12%)

DO

Diamond Offshore

$14.42

-0.07 (-0.48%)

DISH

Dish

$64.44

-0.56 (-0.86%)

BSFT

BroadSoft

$38.40

-0.05 (-0.13%)

CNA

CNA Financial

$45.26

-0.57 (-1.24%)

CMS

CMS Energy

$45.40

-0.09 (-0.20%)

BWP

Boardwalk Pipeline

$18.14

-0.02 (-0.11%)

CAH

Cardinal Health

$72.59

-0.55 (-0.75%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 01

    May

  • 01

    May

  • 01

    May

  • 01

    May

  • 01

    May

  • 01

    May

  • 01

    May

  • 01

    May

  • 01

    May

  • 09

    May

  • 16

    May

  • 17

    May

  • 21

    May

  • 31

    May

19:56
04/30/17
04/30
19:56
04/30/17
19:56
Periodicals
Trump signs two orders on trade, CNN reports »

President Donald Trump on…

TOSBF

Toshiba, also use TOSYY

$2.03

0.06 (3.05%)

, TOSYY

Toshiba, also use TOSBF

$12.14

0.25 (2.10%)

19:45
04/30/17
04/30
19:45
04/30/17
19:45
Periodicals
Innovation Network Corp to lead joint bid for Toshiba chip unit, Nikkei says »

State-backed fund…

TOSBF

Toshiba, also use TOSYY

$2.03

0.06 (3.05%)

TOSYY

Toshiba, also use TOSBF

$12.14

0.25 (2.10%)

WDC

Western Digital

$89.07

3.36 (3.92%)

KKR

KKR

$18.98

0.25 (1.33%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

TRCO

Tribune Media

$36.56

-0.28 (-0.76%)

, FOX

21st Century Fox

$29.86

-0.07 (-0.23%)

19:42
04/30/17
04/30
19:42
04/30/17
19:42
Periodicals
Fox, Blackstone in talks to launch offer for Tribune, FT reports »

Twenty-First Century Fox…

TRCO

Tribune Media

$36.56

-0.28 (-0.76%)

FOX

21st Century Fox

$29.86

-0.07 (-0.23%)

FOXA

21st Century Fox

$30.54

-0.02 (-0.07%)

BX

Blackstone

$30.84

-0.13 (-0.42%)

SBGI

Sinclair Broadcast

$39.45

-0.9 (-2.23%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 03

    May

  • 08

    May

  • 10

    May

  • 15

    Jun

HESM

Hess Midstream Partners

$25.58

0.08 (0.31%)

19:39
04/30/17
04/30
19:39
04/30/17
19:39
Initiation
Hess Midstream Partners initiated at Goldman Sachs »

Hess Midstream Partners…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

SFTBF

SoftBank

$75.98

0.38 (0.50%)

19:28
04/30/17
04/30
19:28
04/30/17
19:28
Periodicals
SoftBank poised to invest more than $1.5B in Paytm, WSJ says »

SoftBank is set to invest…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

NVO

Novo Nordisk

$38.68

-0.1 (-0.26%)

19:12
04/30/17
04/30
19:12
04/30/17
19:12
Periodicals
Novo Nordisk settles probe of drug marketing practices, Bloomberg says »

Novo Nordisk agreed to…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 03

    May

  • 07

    May

  • 06

    Jun

BDRBF

Bombardier

$1.56

-0.0722 (-4.42%)

, BA

Boeing

$184.83

1.61 (0.88%)

19:08
04/30/17
04/30
19:08
04/30/17
19:08
Periodicals
Bombardier says Boeing allegations 'absurd,' Bloomberg reports »

Bombardier (BDRBF) has…

BDRBF

Bombardier

$1.56

-0.0722 (-4.42%)

BA

Boeing

$184.83

1.61 (0.88%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 31

    May

AMZN

Amazon.com

$924.99

6.61 (0.72%)

19:04
04/30/17
04/30
19:04
04/30/17
19:04
Hot Stocks
Amazon to phase out free app program »

Amazon announced in a…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 16

    May

  • 16

    May

  • 23

    May

TSLA

Tesla

$314.07

5.44 (1.76%)

18:28
04/30/17
04/30
18:28
04/30/17
18:28
Periodicals
SolarCity to curtail door-to-door sales tactic, Reuters says »

Tesla's SolarCity is…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 03

    May

  • 30

    May

DIS

Disney

$115.60

-0.24 (-0.21%)

, CMCSA

Comcast

$39.19

-0.4 (-1.01%)

18:16
04/30/17
04/30
18:16
04/30/17
18:16
Periodicals
Hulu likely to unveil cable bundle at end of May, NY Post says »

Hulu will likely unveil…

DIS

Disney

$115.60

-0.24 (-0.21%)

CMCSA

Comcast

$39.19

-0.4 (-1.01%)

CMCSK

Comcast

FOX

21st Century Fox

$29.86

-0.07 (-0.23%)

FOXA

21st Century Fox

$30.54

-0.02 (-0.07%)

TWX

Time Warner

$99.27

-0.63 (-0.63%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 03

    May

  • 08

    May

  • 10

    May

  • 15

    Jun

TCEHY

Tencent

$31.35

-0.11 (-0.35%)

, FB

Facebook

$150.25

2.55 (1.73%)

17:52
04/30/17
04/30
17:52
04/30/17
17:52
Periodicals
Tencent plans to launch VR headset later this year, FT says »

Tencent (TCEHY) is…

TCEHY

Tencent

$31.35

-0.11 (-0.35%)

FB

Facebook

$150.25

2.55 (1.73%)

SSNLF

Samsung

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 03

    May

  • 08

    May

  • 16

    May

CYH

Community Health

$8.61

0.18 (2.14%)

, HCA

HCA Holdings

$84.21

0.77 (0.92%)

17:49
04/30/17
04/30
17:49
04/30/17
17:49
Hot Stocks
Pence: 'Hope' to replace Obamacare before year end »

Speaking in an NBC…

CYH

Community Health

$8.61

0.18 (2.14%)

HCA

HCA Holdings

$84.21

0.77 (0.92%)

LPNT

LifePoint

$62.15

1.4 (2.30%)

THC

Tenet

$15.67

0.2 (1.29%)

UHS

Universal Health

$120.76

2.55 (2.16%)

UNH

UnitedHealth

$174.88

0.25 (0.14%)

KND

Kindred Healthcare

$9.60

0.25 (2.67%)

VTR

Ventas

$64.01

-0.11 (-0.17%)

AET

Aetna

$135.07

1.09 (0.81%)

ANTM

Anthem

$177.89

-0.41 (-0.23%)

CI

Cigna

$156.37

0.16 (0.10%)

HUM

Humana

$221.98

3.31 (1.51%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 02

    May

  • 02

    May

  • 02

    May

  • 02

    May

  • 03

    May

  • 03

    May

  • 04

    May

  • 05

    May

  • 16

    May

  • 18

    May

  • 18

    May

  • 24

    May

  • 31

    May

  • 06

    Jun

  • 13

    Jun

DAL

Delta Air Lines

$45.44

-0.3 (-0.66%)

17:25
04/30/17
04/30
17:25
04/30/17
17:25
Periodicals
Delta pilot returns to duty after possibly striking brawling woman, NYT says »

A Delta pilot who stepped…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 26

    Jun

  • 30

    Jun

TSLA

Tesla

$314.07

5.44 (1.76%)

17:13
04/30/17
04/30
17:13
04/30/17
17:13
Hot Stocks
Tesla CEO hints at plans for additional Gigafactories »

The TED organization has…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 03

    May

  • 30

    May

TSLA

Tesla

$314.07

5.44 (1.76%)

17:03
04/30/17
04/30
17:03
04/30/17
17:03
Periodicals
Tesla CEO releases teaser image of semi truck, Fortune says »

During a "TED"…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 03

    May

  • 30

    May

CMCSA

Comcast

$39.19

-0.4 (-1.01%)

, CMCSK

Comcast

16:47
04/30/17
04/30
16:47
04/30/17
16:47
Hot Stocks
Box Office Battle: 'Furious' crosses $1B as 'Guardians Of Galaxy' preps launch »

Comcast's (CMCSA)…

CMCSA

Comcast

$39.19

-0.4 (-1.01%)

CMCSK

Comcast

LGF.A

Lionsgate

$26.17

-0.11 (-0.42%)

LGF.B

Lionsgate

$23.85

-0.15 (-0.63%)

FOX

21st Century Fox

$29.86

-0.07 (-0.23%)

FOXA

21st Century Fox

$30.54

-0.02 (-0.07%)

DIS

Disney

$115.60

-0.24 (-0.21%)

SNE

Sony

$34.52

0.8 (2.37%)

TWX

Time Warner

$99.27

-0.63 (-0.63%)

VIA

Viacom

$44.60

-0.8 (-1.76%)

VIAB

Viacom

$42.56

-0.75 (-1.73%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 03

    May

  • 04

    May

  • 08

    May

  • 10

    May

  • 24

    May

  • 25

    May

  • 15

    Jun

ELLO

Ellomay Capital

$8.05

0.0019 (0.02%)

14:33
04/30/17
04/30
14:33
04/30/17
14:33
Hot Stocks
Ellomay Capital enters agreement to acquire Talasol Solar »

Ellomay Capital announced…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

GLPG

Galapagos NV

$86.86

0.87 (1.01%)

14:23
04/30/17
04/30
14:23
04/30/17
14:23
Hot Stocks
Galapagos presents preclinical data on osteoarthritis candidate GLPG1972 »

Galapagos announced…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 03

    May

  • 06

    Jun

SO

Southern Company

$49.80

-0.27 (-0.54%)

, TOSBF

Toshiba, also use TOSYY

$2.03

0.06 (3.05%)

14:16
04/30/17
04/30
14:16
04/30/17
14:16
Hot Stocks
Southern Co subsidiary extends interim agreement for Vogtle nuclear expansion »

Georgia Power and…

SO

Southern Company

$49.80

-0.27 (-0.54%)

TOSBF

Toshiba, also use TOSYY

$2.03

0.06 (3.05%)

TOSYY

Toshiba, also use TOSBF

$12.14

0.25 (2.10%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 03

    May

  • 24

    May

CG

Carlyle Group

$17.70

0.2 (1.14%)

14:10
04/30/17
04/30
14:10
04/30/17
14:10
Hot Stocks
Sequa completes recapitalization with participation from Carlyle Group »

Sequa Corp announced…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

IBM

IBM

$160.29

-0.03 (-0.02%)

14:07
04/30/17
04/30
14:07
04/30/17
14:07
Hot Stocks
IBM says granted patent for drone package transfer »

IBM announced Friday that…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

GRAM

Grana y Montero

$3.37

0.07 (2.12%)

14:05
04/30/17
04/30
14:05
04/30/17
14:05
Hot Stocks
Grana y Montero completes sale of PRINSUR stake for $25M »

Grana y Montero announced…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

KO

Coca-Cola

$43.15

0.14 (0.33%)

13:49
04/30/17
04/30
13:49
04/30/17
13:49
Hot Stocks
Coca-Cola Bottling UNITED says closes Georgia transaction with Coca-Cola »

Coca-Cola Bottling…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 09

    May

Get Full Fly Access

Breaking market intelligence sent straight to you
Our team of experts analyze every news story and filter out the noise to deliver real-time market moving news.
Up-to-date information on important industry events
Get real-time updates on events that are moving the market—from conferences and calls to syndicate announcements.
News focused on the companies in your portfolio
Create up to 12 portfolios with 150 stocks each, and see how active they are in market news.