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IONS

Ionis Pharmaceuticals

$30.10

-0.55 (-1.79%)

12:15
10/14/16
10/14
12:15
10/14/16
12:15

Ionis Pharmaceuticals put volume heavy and directionally bearish

Bearish flow noted in Ionis Pharmaceuticals with 1,900 puts trading, or 7x expected. Most active are Oct-16 31 puts and Oct-16 25 puts, with total volume in those strikes near 1,200 contracts. The Put/Call Ratio is 3.17, while ATM IV is up over 5 points on the day. Earnings are expected on November 9th.

  • 29

    Nov

  • 14

    Dec

IONS Ionis Pharmaceuticals
$30.10

-0.55 (-1.79%)

10/06/16
RBCM
10/06/16
NO CHANGE
RBCM
Alnylam news not a negative read through on other RNAi drugs, says RBC Capital
After Alnylam (ALNY) announced that it was discontinuing one of its Phase III RNAi drugs due to poor clinical outcomes, RBC Capital analyst Michael Yee does not thinks that the news indicates problems with all RNAi drugs. Rather, he thinks that RNAi was not the proper treatment for the disease that Alnylam was targeting. Other companies with RNAi treatments include The Medicines Company (MDCO0, Ionis Pharmaceuticals (IONS), Arrowhead (ARWR), and Arbutus Biopharma (ABUS).
10/06/16
WELS
10/06/16
NO CHANGE
WELS
Ionis has no read through from negative Alnylam data, says Wells Fargo
After Ionis (IONS) competitor Alnylam Pharmaceuticals (ALNY) announced that it was terminating the development of its revusiran RNAi drug due to poor outcomes in clinical trials, Wells Fargo thinks that the news is "a significant positive" for Ionis because it eliminates a competitor. The firm says that Ionis' drug is significantly different than Alnylam's product, and it believes that Ionis' treatment appears to be superior. The firm keeps an Outperform rating on Ionis.
10/06/16
BMOC
10/06/16
UPGRADE
BMOC
Outperform
Ionis Pharmaceuticals upgraded on reduced competition, valuation at BMO Capital
As noted earlier, BMO Capital upgraded Ionis (IONS) to Outperform from Market Perform. After Alnylam (ALNY) announced that it was discontinuing one of its Phase III RNAi drugs due to poor clinical outcomes, BMO Capital analyst Do Kim expects Ionis to benefit from the reduced competition. Kim recommends buying Ionis' stock on weakness today. Target to $48 from $42.
10/10/16
WELS
10/10/16
NO CHANGE
WELS
Ionis drug likely to be approved rapidly, says Wells Fargo
After Ionis Pharmaceuticals (IONS) and partner Biogen (BIIB) reported detailed data for their RNA Therapeutic nusinersen, in patients with both symptomatic and pre-symptomatic type 1 Spinal Muscular Atrophy, as well as data for patients with type 2/3 Spinal Muscular Atrophy, or SMA, Wells Fargo says it expects the drug to be rapidly approved. The firm thinks that the FDA will approve "a broad label" covering pre-symptomatic and symptomatic type I SMA, as well as type 2/3 SMA. The firm says that the companies should have "a very large commercial opportunity," and it keeps an Outperform rating on Ionis.

TODAY'S FREE FLY STORIES

RHHBY

Roche

$27.20

-0.1 (-0.37%)

15:21
12/04/16
12/04
15:21
12/04/16
15:21
Conference/Events
Roche to hold an analyst meeting »

Analyst Meeting to…

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  • 05

    Dec

JUNO

Juno Therapeutics

$20.43

0.53 (2.66%)

15:17
12/04/16
12/04
15:17
12/04/16
15:17
Hot Stocks
Juno Therapeutics reports Phase 1 data on JCAR014 »

Juno Therapeutics…

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JUNO

Juno Therapeutics

$20.43

0.53 (2.66%)

15:09
12/04/16
12/04
15:09
12/04/16
15:09
Conference/Events
Juno Therapeutics to host analyst and investor meeting »

Analyst and Investor…

03/08/13
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ATRA

Atara Biotherapeutics

$18.90

-0.3 (-1.56%)

15:04
12/04/16
12/04
15:04
12/04/16
15:04
Hot Stocks
Atara Biotherapeutics reports presentation of Phase 2 CMV-CTL data »

Atara Biotherapeutics…

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JCI

Johnson Controls

$45.32

-0.41 (-0.90%)

15:03
12/04/16
12/04
15:03
12/04/16
15:03
Conference/Events
Johnson Controls to hold a meeting »

Strategic Review &…

03/08/13
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BIIB

Biogen

$297.19

1.41 (0.48%)

14:59
12/04/16
12/04
14:59
12/04/16
14:59
Hot Stocks
Biogen reports data presentations on hemophilia treatments Eloctate, Alprolix »

Biogen and Swedish Orphan…

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GNMSF

Genmab

14:58
12/04/16
12/04
14:58
12/04/16
14:58
Conference/Events
Genmab to hold data review meeting »

Management discusses data…

03/08/13
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03/06/13
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GOOGL

Alphabet Class A

$764.46

0.13 (0.02%)

, GOOG

Alphabet

$750.50

2.58 (0.34%)

14:53
12/04/16
12/04
14:53
12/04/16
14:53
Hot Stocks
Alphabet subsidiary Verily launches utensil product »

Alphabet subsidiary…

GOOGL

Alphabet Class A

$764.46

0.13 (0.02%)

GOOG

Alphabet

$750.50

2.58 (0.34%)

03/08/13
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  • 15

    Jan

KYN

Kayne Anderson

$19.52

0.07 (0.36%)

14:48
12/04/16
12/04
14:48
12/04/16
14:48
Hot Stocks
Kayne Anderson reports net assets $2.2B as of November 30 »

Reports net asset value…

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KED

Kayne Anderson

$19.29

0.03 (0.16%)

14:47
12/04/16
12/04
14:47
12/04/16
14:47
Hot Stocks
Kayne Anderson reports net assets $205M as of November 30 »

Reports net asset value…

03/08/13
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COH

Coach

$36.23

-0.05 (-0.14%)

, BURBY

Burberry

$18.08

0.265 (1.49%)

14:37
12/04/16
12/04
14:37
12/04/16
14:37
Periodicals
Burberry rejected multiple approaches from Coach, FT says »

Burberry (BURBY) rejected…

COH

Coach

$36.23

-0.05 (-0.14%)

BURBY

Burberry

$18.08

0.265 (1.49%)

03/08/13
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03/08/13
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03/06/13
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03/06/13
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UNCFF

UniCredit

$2.22

0.03 (1.37%)

, AMP

Ameriprise

$113.47

-1.57 (-1.36%)

14:31
12/04/16
12/04
14:31
12/04/16
14:31
Periodicals
UniCredit to sell asset manager to Amundi for over EUR 3B, FT says »

UniCredit (UNCFF) is set…

UNCFF

UniCredit

$2.22

0.03 (1.37%)

AMP

Ameriprise

$113.47

-1.57 (-1.36%)

FIG

Fortress

$5.10

-0.1 (-1.92%)

03/08/13
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03/06/13
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03/06/13
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  • 06

    Dec

RXN

Rexnord

$20.27

-0.72 (-3.43%)

14:09
12/04/16
12/04
14:09
12/04/16
14:09
Hot Stocks
Trump targets Rexnord over Mexico relocation plans, says 'no more' »

President-elect Donald…

03/08/13
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T

AT&T

$38.61

-0.27 (-0.69%)

, TWX

Time Warner

$93.80

-0.34 (-0.36%)

13:57
12/04/16
12/04
13:57
12/04/16
13:57
Periodicals
DirecTV NOW unlikely to make money, Barron's says »

AT&T's (T)…

T

AT&T

$38.61

-0.27 (-0.69%)

TWX

Time Warner

$93.80

-0.34 (-0.36%)

03/08/13
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03/08/13
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03/06/13
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03/06/13
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  • 05

    Dec

  • 07

    Dec

  • 07

    Dec

ARCH

Arch Coal

$79.32

1.6 (2.06%)

13:27
12/04/16
12/04
13:27
12/04/16
13:27
Periodicals
Arch Coal could gain 75%, Barron's says »

Arch Coal, which emerged…

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DE

Deere

$101.50

-1.2 (-1.17%)

13:12
12/04/16
12/04
13:12
12/04/16
13:12
Periodicals
Deere could keep climbing, Barron's says »

Deere stock recently…

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JCP

J.C. Penney

$9.81

0.28 (2.94%)

, GME

GameStop

$24.27

-0.37 (-1.50%)

12:57
12/04/16
12/04
12:57
12/04/16
12:57
Periodicals
Corporate tax cut can't save all retailers, Barron's says »

Though President-elect…

JCP

J.C. Penney

$9.81

0.28 (2.94%)

GME

GameStop

$24.27

-0.37 (-1.50%)

AEO

American Eagle

$16.17

-0.57 (-3.41%)

TJX

TJX

$77.10

-0.57 (-0.73%)

FL

Foot Locker

$74.23

0.55 (0.75%)

03/08/13
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  • 05

    Dec

  • 09

    Jan

ELY

Callaway Golf

$11.68

-0.3 (-2.50%)

12:40
12/04/16
12/04
12:40
12/04/16
12:40
Periodicals
Callaway Golf investors should take profits, Barron's says »

It "looks like a…

03/08/13
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EVC

Entravision

12:36
12/04/16
12/04
12:36
12/04/16
12:36
Periodicals
Entravision shares could reach $9, Barron's says »

Hispanic-focused…

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  • 05

    Dec

GOOG

Alphabet

$750.50

2.58 (0.34%)

, GOOGL

Alphabet Class A

$764.46

0.13 (0.02%)

12:26
12/04/16
12/04
12:26
12/04/16
12:26
Periodicals
Barron's picks top ten stocks for 2017 »

Selecting its ten…

GOOG

Alphabet

$750.50

2.58 (0.34%)

GOOGL

Alphabet Class A

$764.46

0.13 (0.02%)

AAPL

Apple

$109.90

0.41 (0.37%)

C

Citi

$56.02

-1.25 (-2.18%)

DAL

Delta Air Lines

$48.31

0.54 (1.13%)

DTEGY

Deutsche Telekom

$15.65

0.14 (0.90%)

MRK

Merck

$61.13

0.37 (0.61%)

NVS

Novartis

$68.17

0.42 (0.62%)

TOL

Toll Brothers

$29.32

0.18 (0.62%)

UL

Unilever; also tag UN

$39.67

0.5 (1.28%)

UN

Unilever; also tag UL

$39.47

0.35 (0.89%)

DIS

Disney

$98.50

-0.44 (-0.44%)

03/08/13
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  • 05

    Dec

  • 06

    Dec

  • 06

    Dec

  • 06

    Dec

  • 12

    Dec

  • 15

    Jan

  • 26

    Jan

  • 08

    Mar

  • 13

    Mar

GMED

Globus Medical

$21.89

0.12 (0.55%)

, TLN

Talen Energy

10:55
12/04/16
12/04
10:55
12/04/16
10:55
Hot Stocks
S&P announces changes to S&P MidCap 400, S&P SmallCap 600 indices »

S&P Dow Jones Indices…

GMED

Globus Medical

$21.89

0.12 (0.55%)

TLN

Talen Energy

UMBF

UMB Financial

$77.00

-0.43 (-0.56%)

IM

Ingram Micro

$38.88

1.31 (3.49%)

HMST

HomeStreet

$29.35

-0.2 (-0.68%)

03/08/13
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03/08/13
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03/06/13
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03/06/13
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FANG

Diamondback Energy

$108.14

-1.86 (-1.69%)

10:55
12/04/16
12/04
10:55
12/04/16
10:55
Syndicate
Breaking Syndicate news story on Diamondback Energy »

Diamondback Energy files…

03/08/13
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03/06/13
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BMRN

BioMarin

$82.21

-1.12 (-1.34%)

, ESALY

Eisai

$57.91

0.59 (1.03%)

04:55
12/04/16
12/04
04:55
12/04/16
04:55
Conference/Events
American Epilepsy Society to hold annual meeting »

70th Annual Meeting of…

BMRN

BioMarin

$82.21

-1.12 (-1.34%)

ESALY

Eisai

$57.91

0.59 (1.03%)

GWPH

GW Pharmaceuticals

$112.32

3.04 (2.78%)

IART

Integra LifeSciences

$75.78

-1.07 (-1.39%)

MDT

Medtronic

$72.01

0.13 (0.18%)

MNK

Mallinckrodt

$53.61

0.51 (0.96%)

NVTA

Invitae

$6.95

0.16 (2.36%)

SAGE

SAGE Therapeutics

$49.02

-0.23 (-0.47%)

WTKWY

Wolters Kluwer

$34.08

-0.39 (-1.13%)

ZGNX

Zogenix

$13.05

0.35 (2.76%)

ZYNE

Zynerba

$13.64

0.83 (6.48%)

03/08/13
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03/06/13
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03/06/13
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  • 05

    Dec

  • 06

    Dec

  • 07

    Dec

  • 12

    Dec

  • 14

    Dec

  • 28

    Jan

  • 27

    Apr

CELG

Celgene

$117.63

-1.24 (-1.04%)

04:55
12/04/16
12/04
04:55
12/04/16
04:55
Conference/Events
Celgene to hold an analyst and investor event »

Management holds an…

03/08/13
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  • 04

    Dec

  • 06

    Dec

INCY

Incyte

$102.02

2.09 (2.09%)

, PFE

Pfizer

$31.63

0.17 (0.54%)

04:55
12/04/16
12/04
04:55
12/04/16
04:55
Conference/Events
Canaccord biotech analyst to hold a dinner meeting »

In conjunction with the…

INCY

Incyte

$102.02

2.09 (2.09%)

PFE

Pfizer

$31.63

0.17 (0.54%)

LLY

Eli Lilly

$67.71

1.74 (2.64%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
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03/06/13
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  • 04

    Dec

  • 06

    Dec

  • 15

    Dec

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