Breaking News Instant updates and real-time market news.

ONCE

Spark Therapeutics

$56.91

0.07 (0.12%)

13:17
10/14/16
10/14
13:17
10/14/16
13:17

Spark Therapeutics presents data reinforcing efficacy of voretigene neparvovec

Spark Therapeutics announced that Principal Investigator Albert M. Maguire, M.D., professor of ophthalmology at the Perelman School of Medicine of the University of Pennsylvania, presented one-year efficacy data from the crossover group and two-year durability data from the original intervention group for the Phase 3 trial of voretigene neparvovec -- formerly SPK-RPE65 -- during Retina Subspecialty Day at the American Academy of Ophthalmology 2016 Annual Meeting in Chicago. Voretigene neparvovec, an investigational gene therapy for Inherited Retinal Disease caused by mutations in the RPE65 gene, has received both breakthrough therapy and orphan product designations from the U.S. FDA, as well as orphan product designations from the EMA. The crossover group consists of nine subjects who, after one year of undergoing the same retinal and visual function testing as the original intervention group, elected to cross over and receive voretigene neparvovec in both eyes. One year after administration, the mean improvement among all nine subjects, as measured by the primary endpoint, a multi-luminance mobility test, was 2.1 lux levels. Dr. Maguire also presented data that showed that the original intervention group subjects who received voretigene neparvovec maintained improvement demonstrated at year one, as measured in MLMT and full-field light sensitivity threshold testing, for at least two years. The mean MLMT improvement of 1.9 lux levels was sustained after two years. The more than 100-fold average improvement in FST testing observed in the original intervention group at one year similarly was maintained through at least two years.

  • 06

    Nov

ONCE Spark Therapeutics
$56.91

0.07 (0.12%)

09/02/16
STFL
09/02/16
INITIATION
STFL
Buy
Spark Therapeutics initiated with a Buy at Stifel
Target $73.
09/02/16
09/02/16
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. AbbVie (ABBV) initiated with an Outperform at Raymond James. 2. Spark Therapeutics (ONCE) initiated with a Buy at Stifel. 3. Cornerstone OnDemand (CSOD) initiated with an Overweight at Piper Jaffray. 4. UR-Energy (URG) initiated with an Outperform at FBR Capital. 5. Energy Transfer Equity (ETE) reinstated with an Overweight at JPMorgan. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
09/21/16
09/21/16
NO CHANGE

RBC identifies top biotech takeover candidates
RBC Capital identified the following names as its top potential takeover candidates in the biotech space: ARIAD (ARIA), Spark Therapeutics (ONCE), BioMarin (BMRN), Aerie Pharmaceuticals (AERI), Intra-Cellular (ITCI), TESARO (TSRO), Incyte (INCY), Sarepta (SRPT), and Puma Biotechnology (PBYI). The firm thinks that investors are underestimating the positive impact that M&A will have on biotech stock prices.
10/07/16
GSCO
10/07/16
NO CHANGE
GSCO
Smid-cap Biotech sector upgraded to Attractive from Neutral at Goldman
Goldman analyst Salveen Richter upgraded the Smid-cap biotechnology to Attractive and said he favors and companies with near-term pipeline data or regulatory events where he has conviction.Names he recommends are Buy rated BioMarin (BMRN), bluebird bio (BLUE), GW Pharma (GWPH), Incyte (INCY), Kite (KITE), and Sage (SAGE).

TODAY'S FREE FLY STORIES

NKE

Nike

$53.24

0.01 (0.02%)

, AMZN

Amazon.com

$939.79

-15.31 (-1.60%)

10:45
09/26/17
09/26
10:45
09/26/17
10:45
Earnings
On The Fly: What to watch in Nike's earnings report »

Nike (NKE) is scheduled…

NKE

Nike

$53.24

0.01 (0.02%)

AMZN

Amazon.com

$939.79

-15.31 (-1.60%)

UA

Under Armour

$15.43

0.04 (0.26%)

UAA

Under Armour

$16.68

-0.06 (-0.36%)

ADDYY

adidas

$113.80

-1.22 (-1.06%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 26

    Sep

  • 03

    Oct

  • 03

    Oct

  • 04

    Oct

  • 22

    Oct

ADDYY

adidas

$113.80

-1.22 (-1.06%)

10:45
09/26/17
09/26
10:45
09/26/17
10:45
Hot Stocks
Adidas says will 'fully cooperate with authorities' after arrest of employee »

Adidas issued the…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

10:45
09/26/17
09/26
10:45
09/26/17
10:45
General news
FX Action: The dollar »

FX Action: The dollar…

GOOG

Alphabet

$920.97

-7.56 (-0.81%)

, GOOGL

Alphabet Class A

$934.28

-8.98 (-0.95%)

10:43
09/26/17
09/26
10:43
09/26/17
10:43
Periodicals
Google to split off shopping service to comply with EU demands, Bloomberg says »

Google is planning to…

GOOG

Alphabet

$920.97

-7.56 (-0.81%)

GOOGL

Alphabet Class A

$934.28

-8.98 (-0.95%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 03

    Oct

  • 22

    Oct

  • 29

    Nov

JPM

JPMorgan

$93.78

-0.34 (-0.36%)

, PNC

PNC Financial

$132.92

-0.6 (-0.45%)

10:40
09/26/17
09/26
10:40
09/26/17
10:40
Hot Stocks
Deutsche moves to the sidelines on JPMorgan, PNC »

Shares of JPMorgan (JPM)…

JPM

JPMorgan

$93.78

-0.34 (-0.36%)

PNC

PNC Financial

$132.92

-0.6 (-0.45%)

GS

Goldman Sachs

$230.47

0.21 (0.09%)

WFC

Wells Fargo

$54.07

0.04 (0.07%)

MS

Morgan Stanley

$47.55

-0.19 (-0.40%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 02

    Oct

  • 03

    Oct

  • 12

    Oct

  • 13

    Oct

  • 13

    Oct

  • 17

    Oct

  • 22

    Oct

  • 29

    Nov

  • 15

    Jan

  • 27

    Feb

  • 13

    Apr

  • 14

    Jul

  • 12

    Oct

RGEN

Repligen

$43.22

-0.54 (-1.23%)

, GE

General Electric

$25.12

0.01 (0.04%)

10:40
09/26/17
09/26
10:40
09/26/17
10:40
Recommendations
Repligen, General Electric analyst commentary  »

Stephens sees GE resin as…

RGEN

Repligen

$43.22

-0.54 (-1.23%)

GE

General Electric

$25.12

0.01 (0.04%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 29

    Sep

  • 02

    Oct

  • 30

    Nov

WEN

Wendy's

$14.91

-0.13 (-0.86%)

10:40
09/26/17
09/26
10:40
09/26/17
10:40
Options
Bullish flow in Wendy's as call buyers gobble up new positions »

Bullish flow in…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 26

    Sep

  • 22

    Oct

10:40
09/26/17
09/26
10:40
09/26/17
10:40
General news
Fed governor Brainard steered clear of policy »

Fed governor Brainard…

10:35
09/26/17
09/26
10:35
09/26/17
10:35
General news
U.S. consumer confidence slipped to 119.8 »

U.S. consumer confidence…

CATM

Cardtronics

$26.10

-3.17 (-10.83%)

10:34
09/26/17
09/26
10:34
09/26/17
10:34
Downgrade
Cardtronics rating change  »

Cardtronics downgraded to…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

PFE

Pfizer

$35.48

-0.03 (-0.08%)

10:30
09/26/17
09/26
10:30
09/26/17
10:30
Options
Bullish option flow in Pfizer »

Bullish option flow in…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 26

    Sep

  • 27

    Sep

  • 27

    Sep

  • 18

    Oct

  • 31

    Oct

  • 08

    Nov

10:30
09/26/17
09/26
10:30
09/26/17
10:30
General news
U.S. Richmond Fed's manufacturing index rose to 19 in September »

U.S. Richmond Fed's…

NSRGY

Nestle

$83.75

0.88 (1.06%)

, VZ

Verizon

$49.83

-0.075 (-0.15%)

10:29
09/26/17
09/26
10:29
09/26/17
10:29
Hot Stocks
Nestle sets new profit targets, though stance on L'Oreal stake unchanged »

Shares of Nestle (NSRGY)…

NSRGY

Nestle

$83.75

0.88 (1.06%)

VZ

Verizon

$49.83

-0.075 (-0.15%)

LRLCY

L'Oreal

$43.13

-0.19 (-0.44%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 26

    Sep

  • 19

    Oct

RGEN

Repligen

$43.22

-0.54 (-1.23%)

, GE

General Electric

$25.09

-0.025 (-0.10%)

10:28
09/26/17
09/26
10:28
09/26/17
10:28
Recommendations
Repligen, General Electric analyst commentary  »

GE launch to weight on…

RGEN

Repligen

$43.22

-0.54 (-1.23%)

GE

General Electric

$25.09

-0.025 (-0.10%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 29

    Sep

  • 02

    Oct

  • 30

    Nov

ADDYY

adidas

$113.80

-1.22 (-1.06%)

, NKE

Nike

$53.21

-0.025 (-0.05%)

10:28
09/26/17
09/26
10:28
09/26/17
10:28
Periodicals
Adidas, Nike employees reportedly named in FBI corruption probe »

The head of sports…

ADDYY

adidas

$113.80

-1.22 (-1.06%)

NKE

Nike

$53.21

-0.025 (-0.05%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 26

    Sep

  • 03

    Oct

  • 04

    Oct

CCL

Carnival

$65.80

2.3 (3.62%)

10:27
09/26/17
09/26
10:27
09/26/17
10:27
Hot Stocks
Carnival says booking volumes for 2018 ahead of prior year »

Says Booking volumes for…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 26

    Sep

10:25
09/26/17
09/26
10:25
09/26/17
10:25
General news
The 3.4% August U.S. new home sales drop »

The 3.4% August U.S. new…

X

U.S. Steel

$24.36

0.305 (1.27%)

10:21
09/26/17
09/26
10:21
09/26/17
10:21
Periodicals
U.S. Steel spokesperson tells Bloomberg company has not sold Slovak unit »

Bloomberg cites U.S.…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

X

U.S. Steel

$24.36

0.305 (1.27%)

10:20
09/26/17
09/26
10:20
09/26/17
10:20
Periodicals
Chinese company nearing acquisition of U.S. Steel's Kosice, Spectator reports »

The sale of U. S.…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

DWDP

DowDuPont

$70.44

0.1 (0.14%)

, LLEX

Lilis Energy

$4.44

0.09 (2.07%)

10:20
09/26/17
09/26
10:20
09/26/17
10:20
Initiation
On The Fly: Top five analyst initiations »

Catch up on today's…click here.

DWDP

DowDuPont

$70.44

0.1 (0.14%)

LLEX

Lilis Energy

$4.44

0.09 (2.07%)

ALDR

Alder Biopharmaceuticals

$11.15

0.3 (2.77%)

CORI

Corium

$10.88

0.03 (0.28%)

TGNA

Tegna

$12.92

0.06 (0.47%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 26

    Sep

  • 26

    Sep

  • 27

    Sep

JPM

JPMorgan

$93.84

-0.28 (-0.30%)

, PNC

PNC Financial

$132.62

-0.905 (-0.68%)

10:20
09/26/17
09/26
10:20
09/26/17
10:20
Downgrade
On The Fly: Top five analyst downgrades »

Catch up on today's…click here.

JPM

JPMorgan

$93.84

-0.28 (-0.30%)

PNC

PNC Financial

$132.62

-0.905 (-0.68%)

AFL

Aflac

$83.23

-1.03 (-1.22%)

CATM

Cardtronics

$26.10

-3.17 (-10.83%)

CAKE

Cheesecake Factory

$41.60

0.08 (0.19%)

SHAK

Shake Shack

$31.60

-2.015 (-6.00%)

HABT

Habit Restaurants

GNCA

Genocea

$5.33

0.04 (0.76%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 26

    Sep

  • 28

    Sep

  • 02

    Oct

  • 12

    Oct

  • 13

    Oct

  • 22

    Oct

  • 27

    Feb

  • 13

    Apr

  • 14

    Jul

  • 12

    Oct

DISCA

Discovery

$21.35

-0.06 (-0.28%)

, MO

Altria Group

$64.87

1.08 (1.69%)

10:20
09/26/17
09/26
10:20
09/26/17
10:20
Upgrade
On The Fly: Top five analyst upgrades »

Catch up on today's…click here.

DISCA

Discovery

$21.35

-0.06 (-0.28%)

MO

Altria Group

$64.87

1.08 (1.69%)

LB

L Brands

$42.77

1.87 (4.57%)

SAM

Boston Beer

$159.25

6.25 (4.09%)

BTI

British American Tobacco

$62.01

0.02 (0.03%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 02

    Nov

NKE

Nike

$53.28

0.05 (0.09%)

10:20
09/26/17
09/26
10:20
09/26/17
10:20
Options
Nike option volume heavy pre-earnings with shares flat near $53.16 »

Nike option volume heavy…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 26

    Sep

  • 03

    Oct

  • 04

    Oct

10:20
09/26/17
09/26
10:20
09/26/17
10:20
General news
U.S. consumer confidence dipped 0.6 points to 119.8 in September »

U.S. consumer confidence…

CCL

Carnival

$65.92

2.4185 (3.81%)

, AAPL

Apple

$150.55

-1.34 (-0.88%)

10:18
09/26/17
09/26
10:18
09/26/17
10:18
Hot Stocks
Carnival to launch digital streaming channel Ocean View »

Continues to project cash…

CCL

Carnival

$65.92

2.4185 (3.81%)

AAPL

Apple

$150.55

-1.34 (-0.88%)

AMZN

Amazon.com

$939.79

-15.31 (-1.60%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 26

    Sep

  • 03

    Oct

  • 22

    Oct

Get Full Fly Access

Breaking market intelligence sent straight to you
Our team of experts analyze every news story and filter out the noise to deliver real-time market moving news.
Up-to-date information on important industry events
Get real-time updates on events that are moving the market—from conferences and calls to syndicate announcements.
News focused on the companies in your portfolio
Create up to 12 portfolios with 150 stocks each, and see how active they are in market news.