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CELG

Celgene

$98.50

-2.13 (-2.12%)

19:19
10/16/16
10/16
19:19
10/16/16
19:19

Celgene reports Phase 1b data on GED-0301 in Crohn's disease

Celgene announced that data from a phase 1b study evaluating the effects of investigational oral GED-0301, or mongersen, on both endoscopic response and clinical remission in patients with active Crohn's disease will be presented at the United European Gastroenterology Week. A total of 63 patients were enrolled in the study. The population was more diverse than prior GED-0301 studies and included patients with endoscopically confirmed mucosal damage at entry and those who had previous surgeries. Results showed that clinical improvement was seen by week 2, and clinical response and remission rates were highest in the 12-week treatment group at 67 and 48 percent respectively, at week 12. The mean CDAI reduction from baseline at week 12 in the 12-week treatment group was 133 points. Of the patients with evaluable endoscopies at week 12, 37 percent had an endoscopic response, with no meaningful difference across treatment groups. In addition, of those patients with greater endoscopic disease activity at baseline, 63 percent exhibited a reduction greater than or equal to 25 percent in SES-CD score and 31 percent had a reduction of greater than or equal to 50 percent. The rates of adverse events and serious adverse events were low and similar across treatment groups. There were no new safety signals for oral GED-0301 160 mg daily reported in this study.

  • 27

    Oct

  • 06

    Nov

CELG Celgene
$98.50

-2.13 (-2.12%)

09/16/16
RBCM
09/16/16
NO CHANGE
RBCM
Celgene shares can advance, says RBC Capital
RBC Capital analyst Michael Yee says that Celgene's stock "can grind higher" as investors eventually understand that the company's GED-0301 drug could potentially generate $1B in revenue. Yee says endoscopy data the company is expected to present next month on GED-0301 "isn't likely to be impressive." However, he thinks the data will "suggest that the drug is working," and he says that investor expectations are low, while the recent pullback in the shares has created an attractive entry point.
09/29/16
SBSH
09/29/16
NO CHANGE
Target $127
SBSH
Buy
Citi ups Celgene target to $127 on luspatercept opportunity
Citi analyst Robyn Karnauskas raised her price target for Celgene (CELG) to $127 from $124 citing greater confidence in the company's myelodysplastic syndrome and beta thalassemia opportunities. After initiating coverage of Celgene partner Acceleron (XLRN) with a Neutral rating, Karnauskas now sees adjusted peak sales for these indications of $1.7B versus $825M previously. Investors are missing the "not-so-distant catalyst" as Phase 3 luspatercept data in these indications could come in late 2017/early 2018, the analyst tells investors in a research note. She keeps a Buy rating on shares of Celgene.
09/30/16
PIPR
09/30/16
NO CHANGE
Target $25
PIPR
Overweight
Piper's Schimmer found Nektar validation at Celgene event
Piper Jaffray analyst Joshua Schimmer says Celgene's (CELG) analyst event provided "another indirect validation" of Nektar Therapeutics' (NKTR) oncology approach. Celgene surprisingly implicated IL-2 as one of the primary mechanisms of Revlimid, Schimmer tells investors in a research note. He views the development as supporting his "enthusiastic outlook" for NKTR-214, the company's long-acting IL-2 targeting Teffector cells. The analyst reiterates an Overweight rating on Nektar with a $25 price target.
10/14/16
ADAM
10/14/16
NO CHANGE
Target $156
ADAM
Buy
Celgene pipeline broader and stronger than ever, says Canaccord
Canaccord analyst John Newman said Celgene's pipeline is broader and stronger than at any point in its history.He reiterated his Buy rating based on his confidence in the commercial potential for GED-0301 for Crohn's disease, ozanimod in both ulcerative colitis and multiple sclerosis, and continued growth for Otezla. Newman reiterated his $156 price target on Celgene shares.

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GOOG

Alphabet

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SRPT

Sarepta

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SRPT

Sarepta

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SRPT

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BSAC

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$23.59

-0.36 (-1.50%)

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BA

Boeing

$183.22

1.51 (0.83%)

, BDRBF

Bombardier

$1.63

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BA

Boeing

$183.22

1.51 (0.83%)

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Bombardier

$1.63

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Bombardier

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SWN

Southwestern Energy

$7.67

-0.16 (-2.04%)

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CRMD

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FET

Forum Energy

$18.10

-1.05 (-5.48%)

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WDC

Western Digital

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FET

Forum Energy

$18.10

-1.05 (-5.48%)

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SJR

Shaw Communications

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MTRX

Matrix Service

$16.88

-0.575 (-3.30%)

18:33
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GIMO

Gigamon

$36.00

-0.6 (-1.64%)

18:33
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MTRX

Matrix Service

$16.88

-0.575 (-3.30%)

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WDC

Western Digital

$85.71

1.1 (1.30%)

, TOSBF

Toshiba, also use TOSYY

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WDC

Western Digital

$85.71

1.1 (1.30%)

TOSBF

Toshiba, also use TOSYY

$1.97

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