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CTRV

ContraVir Pharmaceuticals

$1.96

0.6 (44.12%)

06:06
10/17/16
10/17
06:06
10/17/16
06:06

ContraVir Pharmaceuticals begins enrolling next dosing group for CMX157 trial

ContraVir Pharmaceuticals announced that following a positive recommendation from an independent Data Safety Monitoring Board, or DSMB, the company has begun enrolling the next dosing group in its head-to-head Phase 2a dose-escalation study comparing the safety and efficacy of ContraVir's CMX157 to tenofovir disoproxil fumarate in patients with chronic hepatitis B. ContraVir expects to complete the remaining two escalation cohorts and report top-line results by year-end 2016. The DSMB conducted an independent review of the safety, tolerability and pharmacokinetic profile of CMX157 from the completed 5 mg, 10 mg and 25 mg dosing groups of ContraVir's ongoing, 28-day, Phase 2a study in HBV-infected patients. Based on CMX157's favorable safety and tolerability in this study as well as in a completed Phase 1b study in healthy volunteers, which dosed up to 100 mg of CMX157 per day, the DSMB approved proceeding to a higher dose in the ongoing Phase 2a dose escalation trial per study protocol.

  • 01

    Nov

CTRV ContraVir Pharmaceuticals
$1.96

0.6 (44.12%)

05/06/16
MAXM
05/06/16
INITIATION
Target $4
MAXM
Buy
ContraVir Pharmaceuticals initiated with a Buy at Maxim
Target $4.

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PLYA

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JOBS

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HES

Hess Corp.

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APC

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MAA

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NOC

Northrop Grumman

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