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MRK

Merck

$62.09

0.57 (0.93%)

07:01
10/19/16
10/19
07:01
10/19/16
07:01

Merck says Phase 3 letermovir study met primary endpoint

Merck & Co. announced that the pivotal Phase 3 clinical study of letermovir, an investigational antiviral medicine, met its primary endpoint. The global, multicenter, randomized, placebo-controlled study evaluated the efficacy and safety of letermovir for the prevention of clinically-significant cytomegalovirus infection in adult CMV-seropositive recipients of an allogeneic hematopoietic stem cell transplant. Merck will submit results from the study for presentation at a future scientific conference. In the study, letermovir was administered once daily, either in oral tablet or IV formulation. Letermovir was started as early as the day of HSCT transplant and no later than 28 days post-transplant, and continued through approximately 100 days after transplant. The primary outcome measure was the percentage of participants with clinically-significant CMV infection through 24 weeks after transplant. Under an agreement signed in 2012, Merck purchased worldwide rights to develop and commercialize letermovir from AiCuris GmbH & Co KG.

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MRK Merck
$62.09

0.57 (0.93%)

10/10/16
LEER
10/10/16
NO CHANGE
LEER
Market Perform
Merck 'steals the show' at ESMO with Keytruda data, says Leerink
Leerink analyst Seamus Fernandez said Merck (MRK) stole the show at ESMO with its Keytruda data and he continues to think the company will dominate first line lung cancer treatment for years to come in patients with 50%+ PDL1 expression. Additionally, he expects Merck to gain additional traction in the overall market, noting that confirmation that Keytruda is benefiting patients when combined with Alimta/carboplatin with Alimta maintenance raises the possibility Merck could compete broadly in the overall non-squamous patient population. However, Fernandez keeps a Market Perform rating on Merck, as he thinks its current valuation largely reflects improved growth prospects through 2020.
10/10/16
JMPS
10/10/16
NO CHANGE
JMPS
Incyte treatment looking 'promising,' says JMP Securities
After reviewing recent data, JMP Securities analyst Liisa Bayko says that the combination of Incyte's (INCY) Epacadostat plus Merck's (MRK) Keytruda is "emerging as a promising treatment, potentially even best in class." The analyst says that the progression free survival rate of the combination in melanoma patients "is emerging to be quite competitive," while the efficacy rate in other solid tumors "seemed encouraging." The analyst raised her price target on Incyte to $110 from $100 and keeps an Outperform rating on the stock.
10/13/16
BOFA
10/13/16
UPGRADE
Target $70
BOFA
Buy
Merck upgraded to Buy from Neutral at BofA/Merrill
BofA/Merrill analyst Colin Bristow upgraded Merck to Buy and raised its price target to $70 from $57 to reflect its opportunity in first line lung cancer. Bristow significantly raised his Keytruda sales estmate to 7.5B from $5.5B following Merck's first line lung cancer data presentations at ESMO over the weekend and feedback from experts. He expects Keytruda to receive early approval/launch in first line NSCLC from the December 24 PDUFA and to become the standard of care in the identified label and further upside from chemo combo.
10/13/16
10/13/16
UPGRADE

On The Fly: Top five analyst upgrades
Catch up on today's top five analyst upgrades with this list compiled by The Fly: 1. Merck (MRK) upgraded to Buy from Neutral at BofA/Merrill with analyst Colin Bristow citing its opportunity in first line lung cancer. 2. Viacom (VIA, VIAB) upgraded to Market Perform from Underperform at Wells Fargo and to Buy from Underperform at BofA/Merrill. 3. TD Ameritrade (AMTD) and Charles Schwab (SCHW) were upgraded to Buy from Neutral at BofA/Merrill. 4. Talend (TLND) upgraded to Buy from Neutral at Goldman with analyst Jesse Hulsing saying the company will benefit from analytic workloads moving to the cloud. 5. CSC (CSC) upgraded to Buy from Neutral at Citi. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.

TODAY'S FREE FLY STORIES

GE

General Electric

$27.55

-0.23 (-0.83%)

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BBBY

Bed Bath & Beyond

$33.74

0.08 (0.24%)

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OKE

Oneok

$47.79

0.38 (0.80%)

, OKS

Oneok Partners

$46.94

0.44 (0.95%)

17:59
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Oneok and Oneok Partners merger recommended by two proxy advisory firms »

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OKE

Oneok

$47.79

0.38 (0.80%)

OKS

Oneok Partners

$46.94

0.44 (0.95%)

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GE

General Electric

$27.55

-0.23 (-0.83%)

17:55
06/22/17
06/22
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17:55
Conference/Events
Economic Club of New York to host a meeting »

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  • 22

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SGH

Smart Global

$16.20

0.45 (2.86%)

, IDRA

Idera Pharmaceuticals

$1.73

0.02 (1.17%)

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SGH

Smart Global

$16.20

0.45 (2.86%)

IDRA

Idera Pharmaceuticals

$1.73

0.02 (1.17%)

BAC

Bank of America

$22.93

-0.2 (-0.86%)

BBBY

Bed Bath & Beyond

$33.74

0.08 (0.24%)

SONC

Sonic

$27.50

-0.02 (-0.07%)

AMSWA

American Software

$11.97

0.9 (8.13%)

OCUL

Ocular Therapeutix

$11.54

0.5 (4.53%)

PIR

Pier 1 Imports

$5.14

0.08 (1.58%)

WSM

Williams-Sonoma

$47.18

0.48 (1.03%)

03/08/13
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BBBY

Bed Bath & Beyond

$33.74

0.08 (0.24%)

17:52
06/22/17
06/22
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17:52
Hot Stocks
Breaking Hot Stocks news story on Bed Bath & Beyond »

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  • 22

    Jun

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SUN

Sunoco

$30.11

0.69 (2.35%)

17:51
06/22/17
06/22
17:51
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17:51
Hot Stocks
Sunoco CEO Bob Owens to retire, Joe Kim named COO »

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NVS

Novartis

$86.34

3.78 (4.58%)

, TMO

Thermo Fisher

$175.47

-0.13 (-0.07%)

17:48
06/22/17
06/22
17:48
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17:48
Hot Stocks
Novartis: FDA approves Tafinlar-Mekinist combo in non-small cell lung cancer »

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NVS

Novartis

$86.34

3.78 (4.58%)

TMO

Thermo Fisher

$175.47

-0.13 (-0.07%)

03/08/13
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  • 26

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TMO

Thermo Fisher

$175.47

-0.13 (-0.07%)

, LH

LabCorp

$150.34

4.13 (2.82%)

17:34
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Hot Stocks
Thermo Fisher says FDA grants premarket approval for Oncomine Dx Target Test »

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TMO

Thermo Fisher

$175.47

-0.13 (-0.07%)

LH

LabCorp

$150.34

4.13 (2.82%)

NEO

NeoGenomics

$8.70

0.21 (2.47%)

CGIX

Cancer Genetics

NVS

Novartis

$86.34

3.78 (4.58%)

PFE

Pfizer

$34.06

0.18 (0.53%)

03/08/13
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NGHC

National General

17:32
06/22/17
06/22
17:32
06/22/17
17:32
Syndicate
Breaking Syndicate news story on National General »

National General files to…

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  • 26

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NG

NovaGold

$4.42

0.13 (3.03%)

, ABX

Barrick Gold

$16.09

0.35 (2.22%)

17:29
06/22/17
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17:29
Hot Stocks
NovaGold and Barrick Gold to advance Donlin Gold project with $8M drill program »

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NG

NovaGold

$4.42

0.13 (3.03%)

ABX

Barrick Gold

$16.09

0.35 (2.22%)

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  • 27

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PRXL

Parexel

$87.11

-0.14 (-0.16%)

17:29
06/22/17
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Breaking Hot Stocks news story on Parexel »

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  • 26

    Jun

BBBY

Bed Bath & Beyond

$33.74

0.08 (0.24%)

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Breaking Hot Stocks news story on Bed Bath & Beyond »

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  • 22

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LMT

Lockheed Martin

$280.43

-2.56 (-0.90%)

17:27
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Lockheed Martin awarded $130.8M government contract »

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GD

General Dynamics

$201.26

-2.63 (-1.29%)

17:26
06/22/17
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17:26
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General Dynamics' Electric Boat awarded $203M government contract »

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AAL

American Airlines

$48.97

0.54 (1.12%)

17:23
06/22/17
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17:23
Periodicals
Breaking Periodicals news story on American Airlines »

American Airlines CEO…

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QSR

Restaurant Brands

$61.93

0.08 (0.13%)

17:21
06/22/17
06/22
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17:21
Periodicals
Restaurant Brands to cut use of antibiotics in chicken supply, Reuters reports »

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  • 27

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EMR

Emerson

$58.73

0.09 (0.15%)

17:17
06/22/17
06/22
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17:17
Periodicals
Emerson in talks to buy software firm Paradigm, Bloomberg says »

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TEVA

Teva

$32.52

1.47 (4.73%)

17:15
06/22/17
06/22
17:15
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17:15
Conference/Events
Teva management to meet with Maxim »

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BBBY

Bed Bath & Beyond

$33.74

0.08 (0.24%)

17:10
06/22/17
06/22
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17:10
Hot Stocks
Bed Bath & Beyond says gross margin approximately 36.5% in Q1 »

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  • 22

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LC

LendingClub

$5.70

0.17 (3.07%)

17:05
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Hot Stocks
LendingClub sees using club structure for future transactions »

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TFX

Teleflex

$204.35

0.9 (0.44%)

17:03
06/22/17
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Teleflex says subsidiary issues recall of Venture catheters »

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  • 22

    Jun

ALLY

Ally Financial

$20.39

0.34 (1.70%)

, AXP

American Express

$82.25

0.04 (0.05%)

17:01
06/22/17
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Hot Stocks
All 34 banks exceed minimum requirements of Fed Stress Test »

Shares of big banks were…

ALLY

Ally Financial

$20.39

0.34 (1.70%)

AXP

American Express

$82.25

0.04 (0.05%)

BNPQY

BNP Paribas

$34.42

-0.18 (-0.52%)

BAC

Bank of America

$22.93

-0.2 (-0.86%)

BNK

C1 Financial

BBT

BB&T

$43.34

-0.31 (-0.71%)

BBVA

Banco Bilbao

$8.13

-0.02 (-0.25%)

BMO

Bank of Montreal

$70.67

1.21 (1.74%)

COF

Capital One

$80.39

-0.49 (-0.61%)

CIT

CIT Group

$47.85

0.04 (0.08%)

C

Citi

$63.62

-0.21 (-0.33%)

CFG

Citizens Financial

$34.98

-0.22 (-0.63%)

CMA

Comerica

$71.42

-0.9 (-1.24%)

DB

Deutsche Bank

$16.74

-0.16 (-0.95%)

DFS

Discover

$60.24

-0.12 (-0.20%)

FITB

Fifth Third

$25.14

-0.25 (-0.98%)

GS

Goldman Sachs

$219.77

-2.72 (-1.22%)

HSBC

HSBC

$43.31

-0.16 (-0.37%)

HBAN

Huntington Bancshares

$12.94

-0.12 (-0.92%)

JPM

JPMorgan

$87.02

-0.1 (-0.11%)

KEY

KeyCorp

$18.20

-0.19 (-1.03%)

MTB

M&T Bank

$159.49

-1.54 (-0.96%)

MS

Morgan Stanley

$44.61

-0.3 (-0.67%)

MTU

Mitsubishi UFJ

$6.48

0.06 (0.93%)

NTRS

Northern Trust

$94.34

-0.05 (-0.05%)

PNC

PNC Financial

$120.76

-1.57 (-1.28%)

RF

Regions Financial

$13.84

-0.12 (-0.86%)

SAN

Banco Santander

$6.51

-0.03 (-0.46%)

STT

State Street

$88.68

-0.7 (-0.78%)

STI

SunTrust

$54.73

-0.56 (-1.01%)

TD

Toronto-Dominion

$49.32

0.51 (1.04%)

USB

U.S. Bancorp

$51.30

-0.7 (-1.35%)

WFC

Wells Fargo

$52.49

-0.49 (-0.92%)

ZION

Zions Bancorp

$42.30

-0.03 (-0.07%)

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HAE

Haemonetics

$39.18

-0.91 (-2.27%)

17:01
06/22/17
06/22
17:01
06/22/17
17:01
Hot Stocks
Haemonetics forms Scientific Advisory Council »

Haemonetics announced the…

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  • 22

    Jun

ASCMA

Ascent Capital

$15.00

0.25 (1.69%)

16:55
06/22/17
06/22
16:55
06/22/17
16:55
Hot Stocks
Breaking Hot Stocks news story on Ascent Capital »

Gabelli cuts stake in…

03/08/13
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  • 27

    Jun

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