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ARDX

Ardelyx

$13.25

0.6 (4.74%)

07:04
10/19/16
10/19
07:04
10/19/16
07:04

Ardelyx's tenapanor for IBS-C presents positive global endpoint data

Ardelyx presentated positive global endpoint data from its Phase 2b trial, completed in September 2014, which evaluated tenapanor for the treatment of patients with irritable bowel syndrome with constipation. The company is also evaluating tenapanor in a Phase 3 study for the treatment of hyperphosphatemia in end-stage renal disease patients on dialysis, with data expected to be reported in 1Q17. The IBS symptom global endpoints in the Phase 2b study included: adequate IBS symptom relief; improvements in IBS severity, constipation severity and treatment satisfaction. Compared to placebo, treatment with 50 mg of tenapanor twice a day resulted in statistically significant improvements in all global endpoints measured. 63.1% of patients treated with 50 mg of tenapanor twice a day reported adequate relief of IBS symptoms compared to 39.3% for patients on placebo.

ARDX Ardelyx
$13.25

0.6 (4.74%)

03/09/16
03/09/16
INITIATION

On The Fly: Top Five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. MSG Networks (MSGN) initiated with an Underperform at CLSA by analyst Vasily Karasyov, who expects shares to be range bound given topline pressures from expected subscriber leakage from tiering and proliferation of skinny budgets. 2. FANUC (FANUY) initiated with an Outperform at Bernstein citing the company's technologies and manufacturing capabilities. 3. Ardelyx (ARDX) initiated with a Buy at Cantor. 4. Determine (DTRM) initiated with a Buy at Maxim. 5. Platform Specialty Products (PAH) initiated with a Buy at BofA/Merrill. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
03/29/16
SBSH
03/29/16
NO CHANGE
SBSH
Citi lays out potential targets for next biotech M&A wave
Citi analyst Yigal Nochomovitz believes the setup for the next acquisition cycle in the biotech space is here, but that biotech management's desire to do deals is the missing catalyst. He thinks another one-to-three quarters is needed before "reset valuations are better absorbed as the new reality." Large cap pharma and biotech companies are cash rich and have signaled repeatedly over last year that they are looking for new assets, Nochomovitz tells investors in a research note. He sees a "greater probability" of a takeover over the next 12-18 months for Ardelyx (ARDX), Medivation (MDVN), Ophthotech (OPHT), Puma Biotechnology (PBYI), Portola Pharmaceuticals (PTLA), Ultragenyx (RARE), Relypsa (RLYP) and Versartis (VSAR). He sees a "moderate probability" of a takeover for Anthera (ANTH), Loxo Oncology (LOXO), MacroGenics (MGNX) and Mirati Therapeutics (MRTX). Nochomovitz also sees a "lower probability" of a buyout for Atara Biotherapeutics (ATRA), Chimerix (CMRX), Keryx (KERX) and Mirna Therapeutics (MIRN).
03/31/16
LTCO
03/31/16
INITIATION
Target $21
LTCO
Buy
Ardelyx initiated with a Buy at Ladenburg
Ladenburg analyst Matt Kaplan started Ardelyx with a Buy rating and $21 price target.
04/08/16
SBSH
04/08/16
NO CHANGE
SBSH
Citi lays out potential targets after break of Pfizer, Allergan deal
Citi analysts Yigal Nochomovitz, Liav Abraham and Joel Beatty argue that the break of the Pfizer (PFE), Allergan (AGN) merger could accelerate smaller scale acquisitions in the Biotechnology sector. The implication that larger companies could accelerate M&A activity to bolster pipelines in lieu of the mega-merger pathway aided shares in the sector this week, the analysts contend in a research note. They now believe that Ardelyx (ARDX), Medivation (MDVN), Ophthotech (OPHT), Puma Biotechnology (PBYI), Portola Pharmaceuticals (PTLA), Ultragenyx (RARE), Relypsa (RLYP) and Versartis (VSAR) have a greater probability of being acquired in the next 12-18 months. Beside these favored names for a takeover, analyst Joel Beatty sees a greater chance of Catabasis Pharmaceuticals (CATB), Intercept Pharmaceuticals (ICPT), Novavax (NVAX) and Raptor Pharmaceuticals (RPTP) getting acquired over the next 18 months.

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FB

Facebook

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$90.00

0.45 (0.50%)

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PepsiCo

$114.16

-0.16 (-0.14%)

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State Street

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$53.21

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VZ

Verizon

$46.70

-0.35 (-0.74%)

19:20
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Verizon introduces unlimited prepaid plan »

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NTB

Butterfield

$32.19

0.07 (0.22%)

19:12
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Earnings
Butterfield reports Q1 core EPS 70c, consensus 64c »

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NBIX

Neurocrine

$53.62

1.84 (3.55%)

19:02
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  • 06

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MNOV

MediciNova

$5.57

0.14 (2.58%)

19:02
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  • 25

    Apr

FOX

21st Century Fox

$29.89

0.14 (0.47%)

, FOXA

21st Century Fox

$30.61

0.26 (0.86%)

18:50
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Periodicals
8 more employees join Fox News lawsuit over race discrimination, FT says »

Eight current and former…

FOX

21st Century Fox

$29.89

0.14 (0.47%)

FOXA

21st Century Fox

$30.61

0.26 (0.86%)

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AMRI

Albany Molecular

$17.54

1.63 (10.25%)

, CG

Carlyle Group

$16.70

0.05 (0.30%)

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Albany Molecular receives interest from Pamplona, Carlyle, Bloomberg says »

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AMRI

Albany Molecular

$17.54

1.63 (10.25%)

CG

Carlyle Group

$16.70

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  • 09

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PTIE

Pain Therapeutics

$0.80

0.0285 (3.72%)

18:11
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PTIE

Pain Therapeutics

$0.80

0.0285 (3.72%)

18:10
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Breaking Hot Stocks news story on Pain Therapeutics »

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PTIE

Pain Therapeutics

$0.80

0.0285 (3.72%)

18:09
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Earnings
Pain Therapeutics reports Q1 EPS (6c), one estimate (6c) »

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  • 04

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PHG

Philips

$34.69

0.14 (0.41%)

18:04
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Hot Stocks
Philips Lighting repurchases 3.5M shares for roughly EUR101M »

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PBF

PBF Energy

$22.56

0.26 (1.17%)

, WDR

Waddell & Reed

$17.92

-0.14 (-0.78%)

18:03
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Hot Stocks
S&P announces changes to S&P MidCap 400, S&P SmallCap 600 indices »

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PBF

PBF Energy

$22.56

0.26 (1.17%)

WDR

Waddell & Reed

$17.92

-0.14 (-0.78%)

SWC

Stillwater Mining

$17.99

0.09 (0.50%)

SBGL

Sibanye Gold

$8.14

-0.28 (-3.33%)

ARI

Apollo Commercial

$18.93

0.05 (0.26%)

ZLTQ

ZELTIQ

$56.49

-0.005 (-0.01%)

AGN

Allergan

$238.22

1.24 (0.52%)

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FRO

Frontline

$6.73

0.06 (0.90%)

, DHT

DHT Holdings

$4.67

0.04 (0.86%)

18:02
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04/25
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Hot Stocks
Frontline says makes new offer to DHT Holdings »

Frontline (FRO) issued…

FRO

Frontline

$6.73

0.06 (0.90%)

DHT

DHT Holdings

$4.67

0.04 (0.86%)

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FMBI

First Midwest

$24.11

0.16 (0.67%)

18:01
04/25/17
04/25
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18:01
Earnings
First Midwest reports Q1 adjusted EPS 34c, consensus 33c »

Net interest income…

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FRO

Frontline

$6.73

0.06 (0.90%)

, DHT

DHT Holdings

$4.67

0.04 (0.86%)

18:00
04/25/17
04/25
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Hot Stocks
Breaking Hot Stocks news story on Frontline, DHT Holdings »

Frontline says makes new…

FRO

Frontline

$6.73

0.06 (0.90%)

DHT

DHT Holdings

$4.67

0.04 (0.86%)

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SFLY

Shutterfly

$51.46

0.18 (0.35%)

17:58
04/25/17
04/25
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17:58
Hot Stocks
Shutterfly to retire MyPublisher brand and cite in Q2 »

Comment from company…

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HBNC

Horizon Bancorp

$27.24

0.37 (1.38%)

17:57
04/25/17
04/25
17:57
04/25/17
17:57
Earnings
Horizon Bancorp reports Q1 adjusted EPS 34c, consensus 41c »

Reports Q1 provision for…

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BXP

Boston Properties

$133.97

1.18 (0.89%)

17:57
04/25/17
04/25
17:57
04/25/17
17:57
Earnings
Breaking Earnings news story on Boston Properties »

Boston Properties sees…

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  • 26

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KMT

Kennametal

$40.48

1.15 (2.92%)

17:56
04/25/17
04/25
17:56
04/25/17
17:56
Hot Stocks
Kennametal sees restructuring yielding annual pre-tax savings $165M-$180M »

"Restructuring…

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BXP

Boston Properties

$133.97

1.18 (0.89%)

17:56
04/25/17
04/25
17:56
04/25/17
17:56
Earnings
Breaking Earnings news story on Boston Properties »

Boston Properties sees Q2…

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  • 26

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BXP

Boston Properties

$133.97

1.18 (0.89%)

17:55
04/25/17
04/25
17:55
04/25/17
17:55
Earnings
Boston Properties reports Q1 EPS 63c, consensus 55c »

Reports Q1 revenue…

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