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ARDX

Ardelyx

$13.25

0.6 (4.74%)

07:04
10/19/16
10/19
07:04
10/19/16
07:04

Ardelyx's tenapanor for IBS-C presents positive global endpoint data

Ardelyx presentated positive global endpoint data from its Phase 2b trial, completed in September 2014, which evaluated tenapanor for the treatment of patients with irritable bowel syndrome with constipation. The company is also evaluating tenapanor in a Phase 3 study for the treatment of hyperphosphatemia in end-stage renal disease patients on dialysis, with data expected to be reported in 1Q17. The IBS symptom global endpoints in the Phase 2b study included: adequate IBS symptom relief; improvements in IBS severity, constipation severity and treatment satisfaction. Compared to placebo, treatment with 50 mg of tenapanor twice a day resulted in statistically significant improvements in all global endpoints measured. 63.1% of patients treated with 50 mg of tenapanor twice a day reported adequate relief of IBS symptoms compared to 39.3% for patients on placebo.

ARDX Ardelyx
$13.25

0.6 (4.74%)

03/09/16
03/09/16
INITIATION

On The Fly: Top Five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. MSG Networks (MSGN) initiated with an Underperform at CLSA by analyst Vasily Karasyov, who expects shares to be range bound given topline pressures from expected subscriber leakage from tiering and proliferation of skinny budgets. 2. FANUC (FANUY) initiated with an Outperform at Bernstein citing the company's technologies and manufacturing capabilities. 3. Ardelyx (ARDX) initiated with a Buy at Cantor. 4. Determine (DTRM) initiated with a Buy at Maxim. 5. Platform Specialty Products (PAH) initiated with a Buy at BofA/Merrill. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
03/29/16
SBSH
03/29/16
NO CHANGE
SBSH
Citi lays out potential targets for next biotech M&A wave
Citi analyst Yigal Nochomovitz believes the setup for the next acquisition cycle in the biotech space is here, but that biotech management's desire to do deals is the missing catalyst. He thinks another one-to-three quarters is needed before "reset valuations are better absorbed as the new reality." Large cap pharma and biotech companies are cash rich and have signaled repeatedly over last year that they are looking for new assets, Nochomovitz tells investors in a research note. He sees a "greater probability" of a takeover over the next 12-18 months for Ardelyx (ARDX), Medivation (MDVN), Ophthotech (OPHT), Puma Biotechnology (PBYI), Portola Pharmaceuticals (PTLA), Ultragenyx (RARE), Relypsa (RLYP) and Versartis (VSAR). He sees a "moderate probability" of a takeover for Anthera (ANTH), Loxo Oncology (LOXO), MacroGenics (MGNX) and Mirati Therapeutics (MRTX). Nochomovitz also sees a "lower probability" of a buyout for Atara Biotherapeutics (ATRA), Chimerix (CMRX), Keryx (KERX) and Mirna Therapeutics (MIRN).
03/31/16
LTCO
03/31/16
INITIATION
Target $21
LTCO
Buy
Ardelyx initiated with a Buy at Ladenburg
Ladenburg analyst Matt Kaplan started Ardelyx with a Buy rating and $21 price target.
04/08/16
SBSH
04/08/16
NO CHANGE
SBSH
Citi lays out potential targets after break of Pfizer, Allergan deal
Citi analysts Yigal Nochomovitz, Liav Abraham and Joel Beatty argue that the break of the Pfizer (PFE), Allergan (AGN) merger could accelerate smaller scale acquisitions in the Biotechnology sector. The implication that larger companies could accelerate M&A activity to bolster pipelines in lieu of the mega-merger pathway aided shares in the sector this week, the analysts contend in a research note. They now believe that Ardelyx (ARDX), Medivation (MDVN), Ophthotech (OPHT), Puma Biotechnology (PBYI), Portola Pharmaceuticals (PTLA), Ultragenyx (RARE), Relypsa (RLYP) and Versartis (VSAR) have a greater probability of being acquired in the next 12-18 months. Beside these favored names for a takeover, analyst Joel Beatty sees a greater chance of Catabasis Pharmaceuticals (CATB), Intercept Pharmaceuticals (ICPT), Novavax (NVAX) and Raptor Pharmaceuticals (RPTP) getting acquired over the next 18 months.

TODAY'S FREE FLY STORIES

GM

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0.32 (0.82%)

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Wells Fargo

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EADSY

Airbus

$23.06

-0.01 (-0.04%)

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DGX

Quest Diagnostics

$102.11

0.56 (0.55%)

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IRBT

iRobot

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-3.8 (-4.75%)

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XLNX

Xilinx

$69.33

0.42 (0.61%)

, SNPS

Synopsys

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0.3 (0.37%)

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UTX

United Technologies

$115.01

0.51 (0.45%)

, COL

Rockwell Collins

$130.48

0.09 (0.07%)

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UTX

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BA

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$256.45

0.41 (0.16%)

EADSY

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$23.06

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  • 23

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GPRO

GoPro

$10.75

-0.19 (-1.74%)

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HMC

Honda

$29.91

0.18 (0.61%)

, RACE

Ferrari

$113.47

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Honda

$29.91

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Ferrari

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ORCL

Oracle

$48.16

0.19 (0.40%)

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SIX

Six Flags

$58.96

1.14 (1.97%)

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  • 28

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ONCE

Spark Therapeutics

$85.15

-1.95 (-2.24%)

, AVXS

AveXis

$92.11

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Regenxbio

$28.25

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BOLD

Audentes Therapeutics

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VYGR

Voyager Therapeutics

$17.50

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AET

Aetna

$153.57

0.18 (0.12%)

, ANTM

Anthem

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CI

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HUM

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MOH

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UNH

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AOBC

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WMT

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PEP

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MSFT

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AMZN

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TWTR

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GOOGL

Alphabet Class A

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FB

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AVA

Avista

$51.40

0.1 (0.19%)

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BMWYY

BMW

$34.00

0.083 (0.24%)

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CSCO

Cisco

$33.37

0.67 (2.05%)

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BMY

Bristol-Myers

$63.36

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Bristol-Myers announces FDA approval of Opdivo »

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INSE

Inspired Entertainment

$13.60

0.3 (2.26%)

17:38
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Inspired Entertainment COO Wilson leaving by reason of redundancy »

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  • 28

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MNOV

MediciNova

$6.18

0.3 (5.10%)

17:30
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Breaking Syndicate news story on MediciNova »

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  • 26

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ISRG

Intuitive Surgical

$1,031.52

1.31 (0.13%)

17:25
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Intuitive Surgical to host special shareholder meeting »

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  • 22

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GD

General Dynamics

$205.41

-0.31 (-0.15%)

17:21
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General Dynamics Electric Boat awarded $341.2M government contract modification »

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CHRS

Coherus Biosciences

$12.85

0.3 (2.39%)

17:19
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Syndicate
Breaking Syndicate news story on Coherus Biosciences »

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  • 25

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FIBK

First Interstate

$36.90

0.3 (0.82%)

17:18
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17:18
Syndicate
First Interstate files to sell $250M of Class A common stock »

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NRCIA

National Research, also tag NRCIB

$37.45

0.55 (1.49%)

, NRCIB

National Research, also tag NRCIA

$54.30

0.31 (0.57%)

17:08
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National Research launches metric to measure healthcare consumer loyalty »

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National Research, also tag NRCIB

$37.45

0.55 (1.49%)

NRCIB

National Research, also tag NRCIA

$54.30

0.31 (0.57%)

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CC

Chemours

$51.79

-0.16 (-0.31%)

, HON

Honeywell

$141.75

0.89 (0.63%)

16:58
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Chemours files appeal concerning SNAP 20 rule to regulate HFCs »

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CC

Chemours

$51.79

-0.16 (-0.31%)

HON

Honeywell

$141.75

0.89 (0.63%)

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