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ARDX

Ardelyx

$13.25

0.6 (4.74%)

07:04
10/19/16
10/19
07:04
10/19/16
07:04

Ardelyx's tenapanor for IBS-C presents positive global endpoint data

Ardelyx presentated positive global endpoint data from its Phase 2b trial, completed in September 2014, which evaluated tenapanor for the treatment of patients with irritable bowel syndrome with constipation. The company is also evaluating tenapanor in a Phase 3 study for the treatment of hyperphosphatemia in end-stage renal disease patients on dialysis, with data expected to be reported in 1Q17. The IBS symptom global endpoints in the Phase 2b study included: adequate IBS symptom relief; improvements in IBS severity, constipation severity and treatment satisfaction. Compared to placebo, treatment with 50 mg of tenapanor twice a day resulted in statistically significant improvements in all global endpoints measured. 63.1% of patients treated with 50 mg of tenapanor twice a day reported adequate relief of IBS symptoms compared to 39.3% for patients on placebo.

ARDX Ardelyx
$13.25

0.6 (4.74%)

03/09/16
03/09/16
INITIATION

On The Fly: Top Five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. MSG Networks (MSGN) initiated with an Underperform at CLSA by analyst Vasily Karasyov, who expects shares to be range bound given topline pressures from expected subscriber leakage from tiering and proliferation of skinny budgets. 2. FANUC (FANUY) initiated with an Outperform at Bernstein citing the company's technologies and manufacturing capabilities. 3. Ardelyx (ARDX) initiated with a Buy at Cantor. 4. Determine (DTRM) initiated with a Buy at Maxim. 5. Platform Specialty Products (PAH) initiated with a Buy at BofA/Merrill. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
03/29/16
SBSH
03/29/16
NO CHANGE
SBSH
Citi lays out potential targets for next biotech M&A wave
Citi analyst Yigal Nochomovitz believes the setup for the next acquisition cycle in the biotech space is here, but that biotech management's desire to do deals is the missing catalyst. He thinks another one-to-three quarters is needed before "reset valuations are better absorbed as the new reality." Large cap pharma and biotech companies are cash rich and have signaled repeatedly over last year that they are looking for new assets, Nochomovitz tells investors in a research note. He sees a "greater probability" of a takeover over the next 12-18 months for Ardelyx (ARDX), Medivation (MDVN), Ophthotech (OPHT), Puma Biotechnology (PBYI), Portola Pharmaceuticals (PTLA), Ultragenyx (RARE), Relypsa (RLYP) and Versartis (VSAR). He sees a "moderate probability" of a takeover for Anthera (ANTH), Loxo Oncology (LOXO), MacroGenics (MGNX) and Mirati Therapeutics (MRTX). Nochomovitz also sees a "lower probability" of a buyout for Atara Biotherapeutics (ATRA), Chimerix (CMRX), Keryx (KERX) and Mirna Therapeutics (MIRN).
03/31/16
LTCO
03/31/16
INITIATION
Target $21
LTCO
Buy
Ardelyx initiated with a Buy at Ladenburg
Ladenburg analyst Matt Kaplan started Ardelyx with a Buy rating and $21 price target.
04/08/16
SBSH
04/08/16
NO CHANGE
SBSH
Citi lays out potential targets after break of Pfizer, Allergan deal
Citi analysts Yigal Nochomovitz, Liav Abraham and Joel Beatty argue that the break of the Pfizer (PFE), Allergan (AGN) merger could accelerate smaller scale acquisitions in the Biotechnology sector. The implication that larger companies could accelerate M&A activity to bolster pipelines in lieu of the mega-merger pathway aided shares in the sector this week, the analysts contend in a research note. They now believe that Ardelyx (ARDX), Medivation (MDVN), Ophthotech (OPHT), Puma Biotechnology (PBYI), Portola Pharmaceuticals (PTLA), Ultragenyx (RARE), Relypsa (RLYP) and Versartis (VSAR) have a greater probability of being acquired in the next 12-18 months. Beside these favored names for a takeover, analyst Joel Beatty sees a greater chance of Catabasis Pharmaceuticals (CATB), Intercept Pharmaceuticals (ICPT), Novavax (NVAX) and Raptor Pharmaceuticals (RPTP) getting acquired over the next 18 months.

TODAY'S FREE FLY STORIES

RNECY

Renesas

$4.14

-0.17 (-3.94%)

, ISIL

Intersil

19:04
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Renesas

$4.14

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ISIL

Intersil

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HSIC

Henry Schein

$173.53

1.61 (0.94%)

18:45
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Conference/Events
Henry Schein management to meet with Jefferies »

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    Feb

TWX

Time Warner

$97.28

0.6225 (0.64%)

18:38
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02/24
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Periodicals
Turner, Univision to win U.S. Champions League rights, Bloomberg reports »

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    Mar

TRUE

TrueCar

$14.28

0.18 (1.28%)

18:33
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02/24
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18:33
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TrueCar's ALG sees February total new vehicle sales 1.325M units, down 1.4% »

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    Feb

GE

General Electric

$30.19

0.17 (0.57%)

18:24
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02/24
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18:24
Hot Stocks
GE does not see after-tax charges from GE Capital exit plan to exceed $23B »

GE said in a regulatory…

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CE

Celanese

$88.79

-0.88 (-0.98%)

18:02
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Hot Stocks
Celanese announces vinyl acetate-based emulsions price increases in Asia »

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    Feb

ELNK

EarthLink

$5.63

-0.22 (-3.76%)

, WIN

Windstream

$7.27

-0.02 (-0.27%)

17:56
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02/24
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17:56
Hot Stocks
EarthLink, Windstream holders approve merger »

EarthLink (ELNK)…

ELNK

EarthLink

$5.63

-0.22 (-3.76%)

WIN

Windstream

$7.27

-0.02 (-0.27%)

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PFE

Pfizer

$34.26

0.2 (0.59%)

17:43
02/24/17
02/24
17:43
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17:43
Periodicals
Pfizer subpoenaed in investigation of charity connections, Bloomberg says »

Pfizer has received two…

03/08/13
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C

Citi

$59.56

-1.06 (-1.75%)

17:32
02/24/17
02/24
17:32
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17:32
Hot Stocks
U.S. regulators investigating Citi over foreign hiring practices »

In a regulatory filing,…

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FDX

FedEx

$193.11

1.93 (1.01%)

17:25
02/24/17
02/24
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17:25
Hot Stocks
FedEx, USPS amend transportation agreement »

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URRE

Uranium Resources

$1.94

-0.09 (-4.43%)

17:21
02/24/17
02/24
17:21
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17:21
Syndicate
Breaking Syndicate news story on Uranium Resources »

Uranium Resources files…

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RTN

Raytheon

$153.48

0.19 (0.12%)

17:13
02/24/17
02/24
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17:13
Hot Stocks
Raytheon awarded $1B government contract »

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COTV

Cotiviti Holdings

$38.74

-0.06 (-0.15%)

17:06
02/24/17
02/24
17:06
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17:06
Syndicate
Breaking Syndicate news story on Cotiviti Holdings »

Cotiviti Holdings files…

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  • 22

    Mar

ENH

Endurance Specialty

$92.90

0.02 (0.02%)

17:05
02/24/17
02/24
17:05
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17:05
Earnings
Endurance reports Q4 EPS 30c, may not compare to consensus $1.26 »

Reports Q4 gross premiums…

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ORPN

Bio Blast Pharma

$1.13

-0.0098 (-0.86%)

17:04
02/24/17
02/24
17:04
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17:04
Syndicate
Breaking Syndicate news story on Bio Blast Pharma »

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MNTA

Momenta

$15.40

0.3 (1.99%)

, PFE

Pfizer

$34.26

0.2 (0.59%)

16:44
02/24/17
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16:44
General news
On The Fly: Stocks end week higher as rally continues »

Stocks ended the week…

MNTA

Momenta

$15.40

0.3 (1.99%)

PFE

Pfizer

$34.26

0.2 (0.59%)

STLD

Steel Dynamics

$35.59

0.07 (0.20%)

AKS

AK Steel

$8.02

-0.1 (-1.23%)

X

U.S. Steel

$37.01

-0.3 (-0.80%)

FLR

Fluor

$55.09

-0.26 (-0.47%)

GVA

Granite Construction

$53.91

0.78 (1.47%)

VMC

Vulcan Materials

$117.82

1.47 (1.26%)

PWR

Quanta Services

$37.76

0.62 (1.67%)

ACM

AECOM

$35.77

-0.58 (-1.60%)

JEC

Jacobs Engineering

$56.03

-0.07 (-0.12%)

KBR

KBR

$15.60

-0.55 (-3.41%)

CBI

CB&I

$33.87

-0.02 (-0.06%)

MTZ

MasTec

$40.10

3.05 (8.23%)

KHC

Kraft Heinz

$93.08

0.14 (0.15%)

UN

Unilever; also tag UL

$46.91

0.33 (0.71%)

UL

Unilever; also tag UN

$47.12

0.22 (0.47%)

QSR

Restaurant Brands

$55.47

-0.08 (-0.14%)

PLKI

Popeyes

TROX

Tronox

$17.40

-0.67 (-3.71%)

WMT

Wal-Mart

$72.39

1.08 (1.51%)

HD

Home Depot

$145.95

1.24 (0.86%)

CYH

Community Health

$9.22

0.32 (3.60%)

TOL

Toll Brothers

$33.74

-0.22 (-0.65%)

GRMN

Garmin

$53.03

0.72 (1.38%)

CHS

Chico's

$14.75

0.3 (2.08%)

HPQ

HP Inc.

$17.65

0.05 (0.28%)

CRI

Carter's

$90.04

2.98 (3.42%)

SQ

Square

$17.43

0.28 (1.63%)

JWN

Nordstrom

$46.46

2.52 (5.74%)

FL

Foot Locker

$75.01

6.43 (9.38%)

AAOI

Applied Optoelectronics

$45.98

8.51 (22.71%)

RH

Restoration Hardware

$31.34

6.15 (24.41%)

M

Macy's

$33.17

0.73 (2.25%)

PZZA

Papa John's

$78.70

-0.07 (-0.09%)

FSLR

First Solar

$37.90

0.71 (1.91%)

TXRH

Texas Roadhouse

$42.22

0.13 (0.31%)

TSLA

Tesla

$257.00

1.01 (0.39%)

LB

Labarge

$50.99

2.05 (4.19%)

W

Wayfair

$39.30

0.72 (1.87%)

HPE

HP Enterprise

$22.96

-1.7 (-6.89%)

JCP

J.C. Penney

$6.46

-0.4 (-5.83%)

ACIA

Acacia Communications

$54.04

-9.39 (-14.80%)

BGS

B&G Foods

$43.65

-3.25 (-6.93%)

SPLK

Splunk

$62.80

-2.1 (-3.24%)

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NBEV

New Age Beverages

$3.90

-0.04 (-1.02%)

16:41
02/24/17
02/24
16:41
02/24/17
16:41
Hot Stocks
Breaking Hot Stocks news story on New Age Beverages »

Park West AM reports 6.3%…

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CYTX

Cytori Therapeutics

$1.71

-0.07 (-3.93%)

16:40
02/24/17
02/24
16:40
02/24/17
16:40
Hot Stocks
Breaking Hot Stocks news story on Cytori Therapeutics »

Azaya Therapeutics…

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ADMA

ADMA Biologics

$4.75

-0.03 (-0.63%)

16:40
02/24/17
02/24
16:40
02/24/17
16:40
Earnings
ADMA Biologics reports FY16 EPS ($1.61), consensus ($1.57) »

Reports FY16 revenue…

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WFC

Wells Fargo

$57.81

-0.68 (-1.16%)

16:38
02/24/17
02/24
16:38
02/24/17
16:38
Syndicate
Breaking Syndicate news story on Wells Fargo »

Wells Fargo files…

03/08/13
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  • 13

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    Jul

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  • 15

    Jan

SHO

Sunstone Hotel

$14.71

-0.05 (-0.34%)

16:36
02/24/17
02/24
16:36
02/24/17
16:36
Syndicate
Breaking Syndicate news story on Sunstone Hotel »

Sunstone Hotel files…

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TPHS

Trinity Place

$9.97

0.47 (4.95%)

16:36
02/24/17
02/24
16:36
02/24/17
16:36
Hot Stocks
Breaking Hot Stocks news story on Trinity Place »

Horse Island Partners…

03/08/13
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SO

Southern Company

$50.50

0.83 (1.67%)

16:35
02/24/17
02/24
16:35
02/24/17
16:35
Syndicate
Breaking Syndicate news story on Southern Company »

Southern Company's…

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  • 28

    Feb

MENT

Mentor Graphics

, SIEGY

Siemens

$128.94

-1.35 (-1.04%)

16:35
02/24/17
02/24
16:35
02/24/17
16:35
Hot Stocks
KFTC clears pending merger of Mentor Graphics and Siemens »

According to a regulatory…

MENT

Mentor Graphics

SIEGY

Siemens

$128.94

-1.35 (-1.04%)

03/08/13
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  • 27

    Feb

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    Feb

HPE

HP Enterprise

$22.96

-1.7 (-6.89%)

, JCP

J.C. Penney

$6.46

-0.4 (-5.83%)

16:32
02/24/17
02/24
16:32
02/24/17
16:32
General news
On The Fly: Top stock stories for Friday »

Stocks opened with modest…

HPE

HP Enterprise

$22.96

-1.7 (-6.89%)

JCP

J.C. Penney

$6.46

-0.4 (-5.83%)

JWN

Nordstrom

$46.46

2.52 (5.74%)

FL

Foot Locker

$75.01

6.43 (9.38%)

RH

Restoration Hardware

$31.34

6.15 (24.41%)

ACIA

Acacia Communications

$54.04

-9.39 (-14.80%)

BGS

B&G Foods

$43.65

-3.25 (-6.93%)

03/08/13
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03/06/13
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03/06/13
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