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CERU

Cerulean

$0.68

-0.0168 (-2.41%)

, NVS

Novartis

$76.31

0.73 (0.97%)

08:08
10/19/16
10/19
08:08
10/19/16
08:08

Cerulean announces strategic collaboration with Novartis

Cerulean Pharma (CERU) announced that the company has entered into a strategic collaboration with Novartis (NVS) to develop NDC product candidates combining Cerulean's proprietary Dynamic Tumor Targeting technology with Novartis' proprietary compounds directed at up to five targets. Cerulean will create NDC candidates, and Novartis is responsible for further development and commercialization of NDC products resulting from the collaboration. Under terms of the agreement, Cerulean will receive an upfront payment of $5M plus funding for five full-time equivalents. Cerulean is also eligible to receive preclinical, clinical, regulatory, and sales milestones for each target. In addition, following regulatory approval of NDC products, Cerulean can earn single-digit to low double-digit tiered royalties on net sales for each NDC product.

CERU

Cerulean

$0.68

-0.0168 (-2.41%)

NVS

Novartis

$76.31

0.73 (0.97%)

  • 11

    Nov

CERU Cerulean
$0.68

-0.0168 (-2.41%)

08/18/16
JMPS
08/18/16
DOWNGRADE
JMPS
Market Perform
Cerulean downgraded to Market Perform from Outperform at JMP Securities
JMP Securities analyst Michael King downgraded Cerulean after the company announced negative top-line results from a study of its CRLX101 drug in patients with advanced renal cell carcinoma. Noting that the study indicated that there was no difference between the results of patients taking CRLX101 and those taking the standard treatment, King says that the stock is fairly valued at current levels.
08/18/16
ROTH
08/18/16
NO CHANGE
Target $2.5
ROTH
Buy
Roth Capital trims Cerulean price target, but remains a buyer
Roth Capital analyst Joseph Pantginis lowered his price target for Cerulean to $2.50 from $9 after the company's Phase 2 clinical trial of CRLX101 for advanced renal cell carcinoma, or RCC, demonstrated no statistically significant difference. Nonetheless, with a platform technology providing long-term pipeline fill and improvements in tumor targeting, Pantginis believes Cerulean remains an attractive opportunity despite the failure in late-stage RCC. He reiterates a Buy rating on the shares.
08/18/16
08/18/16
DOWNGRADE

On The Fly: Top five analyst downgrades
Catch up on today's top five analyst downgrades with this list compiled by The Fly: 1. Twitter (TWTR) downgraded to Sell from Hold at Evercore ISI with analyst Ken Sena saying he sees "more risk than reward" ahead of Snapchat's anticipated monetization ramp this fall. 2. Ambev (ABEV) downgraded to Equal Weight from Overweight at Morgan Stanley with analyst Jeronimo De Guzman saying valuation is full and sees difficult near-term trends ahead given lower disposable income, volume weakness, and lower realized pricing. 3. Icahn Enterprises (IEP) downgraded to Sell from Neutral at UBS saying the company's net asset value, despite declining 49% since second quarter of 2015, seems to include optimistic valuations. 4. Cerulean (CERU) downgraded to Neutral from Buy at Janney Capital, to Market Perform from Outperform at Leerink, and to Market Perform from Outperform at JMP Securities. 5. Magellan Midstream (MMP) downgraded to Underweight at Morgan Stanley with analysts led by Tom Abrams citing a relatively high valuation as the number of lower multiple investment choices has increased. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
08/18/16
WEDB
08/18/16
DOWNGRADE
WEDB
Neutral
Cerulean downgraded to Neutral from Outperform at Wedbush
NVS Novartis
$76.31

0.73 (0.97%)

08/31/16
PIPR
08/31/16
NO CHANGE
PIPR
Piper's Schimmer unsure of impact from Novartis CAR-T shakeup
Piper Jaffray analyst Joshua Schimmer said he's struggling with the implications of the news that Novartis (NVS) is reportedly eliminating its Cell and Gene Therapy unit as a stand-alone entity, which is primarily focused on development of CAR-T and adoptive immunotherapies. On the one hand, removing a leading competitor is a positive for the rest of the field, Schimmer tells investors in a research note. On the other hand, the move by Novartis could signal "significant challenges" in the field, the analyst adds. Schimmer continues to prefer companies "with unique and differentiated approaches," namely Bellicum Pharmaceuticals (BLCM), Cellectis (CLLS), Lion Biotechnologies (LBIO), Amgen (AMGN), Celgene (CELG) and bluebird bio (BLUE). Juno Therapeutics (JUNO) and Kite Pharma (KITE) are down 6% and 5%, respectively, in midday trading.
09/02/16
LEER
09/02/16
NO CHANGE
LEER
Outperform
Teva third Copaxone patent invalidated as expected, says Leerink
Leerink analyst Jason Gerberry says Teva (TEVA) suffered a largely expected loss in its Copaxone 40mg patent battle, with the Patent Trial and Appeal Board, or PTAB, ruling a third patent invalid. The analyst believes the company will likely appeal the loss, along with PTAB rulings rendered last week that other Copaxone patents were invalid. Gerberry sees the bull case scenario of Teva securing patent exclusivity of the Copaxone 40mg as unlikely and says a settlement with Momenta (MNTA) and Novartis (NVS) is the most logical course of action to mitigate 2017-2018E EPS risk. He reiterates an Outperform rating on Teva's shares.
09/20/16
CHDN
09/20/16
INITIATION
Target $95
CHDN
Buy
Novartis initiated with a Buy at Chardan
Chardan initiated Novartis with a Buy and a $95 price target.
10/13/16
JEFF
10/13/16
DOWNGRADE
Target $36
JEFF
Hold
Pfizer downgraded to Hold from Buy at Jefferies
Jefferies analyst Jeffrey Holford downgraded Pfizer (PFE) to Hold citing a lack of positive catalysts. The analyst says the drivers for his upgrade to Buy have either played out or have not materialized, namely an inversion or GEP unit separation. To reflect the infusion business disposal and weaker Ibrance trends, Holford cut his mid-term earnings estimates for Pfizer by up to 7% and cut his price target for the shares to $36 from $39. The stock closed yesterday down 6c to $33.07. The analyst also sees increased risk of a major acquisition occurring over the next 12 months. In the global pharma space, Holford lists AbbVie (ABBV), Eli Lilly (LLY), Novartis (NVS) and AstraZeneca (AZN) as his top picks.

TODAY'S FREE FLY STORIES

HRTX

Heron Therapeutics

$13.75

-0.1 (-0.72%)

08:03
02/24/17
02/24
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08:03
Hot Stocks
Heron Therapeutics reports inclusion of SUSTOL ER injection in NCCN guidelines »

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NXTD

Nxt-ID

$2.12

-0.2 (-8.62%)

08:03
02/24/17
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08:03
Hot Stocks
Nxt-ID responds to law firm press release »

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MRK

Merck

$65.85

0.56 (0.86%)

, GILD

Gilead

$69.37

0.54 (0.78%)

08:02
02/24/17
02/24
08:02
02/24/17
08:02
Recommendations
Merck, Gilead, AbbVie analyst commentary  »

Merck write-down suggests…

MRK

Merck

$65.85

0.56 (0.86%)

GILD

Gilead

$69.37

0.54 (0.78%)

ABBV

AbbVie

$61.94

0.58 (0.95%)

03/08/13
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AES

AES Corp.

$11.75

0.15 (1.29%)

08:02
02/24/17
02/24
08:02
02/24/17
08:02
Hot Stocks
AES Corp., AIMCo to acquire sPower from Fir Tree Partners for $853M plus debt »

The AES Corporation and…

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VALE

Vale

$10.75

-0.49 (-4.36%)

08:02
02/24/17
02/24
08:02
02/24/17
08:02
Periodicals
Vale CEO Ferreira to step down, DJ reports »

Dow Jones has corrected…

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MA

MasterCard

$110.74

1.3 (1.19%)

08:01
02/24/17
02/24
08:01
02/24/17
08:01
Hot Stocks
MasterCard to integrate Masterpass into Gulf Oil's Gulf Pay »

Mastercard announced…

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  • 14

    Mar

VALE

Vale

$10.75

-0.49 (-4.36%)

08:01
02/24/17
02/24
08:01
02/24/17
08:01
Options
Vale put buyer realizes 25% same-day gains »

Notable profits for the…

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SATS

EchoStar

$55.24

-0.29 (-0.52%)

08:01
02/24/17
02/24
08:01
02/24/17
08:01
Earnings
EchoStar reports Q4 EPS 40c, consensus 38c »

Reports Q4 revenue $740M,…

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FLS

Flowserve

$46.78

-1.87 (-3.84%)

08:00
02/24/17
02/24
08:00
02/24/17
08:00
Hot Stocks
Flowserve names Jay Roueche interim CEO, effective immediately »

Flowserve Corporation,…

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ZYNE

Zynerba

$22.10

0.27 (1.24%)

07:59
02/24/17
02/24
07:59
02/24/17
07:59
Initiation
Zynerba initiated  »

Zynerba initiated with a…

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  • 21

    Mar

NGVT

Ingevity

$54.35

-2.06 (-3.65%)

07:58
02/24/17
02/24
07:58
02/24/17
07:58
Recommendations
Ingevity analyst commentary  »

Ingevity weakness creates…

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USM

U.S. Cellular

$44.84

-0.37 (-0.82%)

07:58
02/24/17
02/24
07:58
02/24/17
07:58
Earnings
U.S. Cellular sees FY17 revenue $3.8B-$4B, consensus $4.05B »

Sees FY17 adjusted EBITDA…

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  • 24

    Feb

BSX

Boston Scientific

$24.48

-0.68 (-2.70%)

07:57
02/24/17
02/24
07:57
02/24/17
07:57
Recommendations
Boston Scientific analyst commentary  »

Selloff in Boston…

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USM

U.S. Cellular

$44.84

-0.37 (-0.82%)

07:57
02/24/17
02/24
07:57
02/24/17
07:57
Earnings
U.S. Cellular reports Q4 EPS (7c), consensus (25c) »

Reports Q4 revenue $991M,…

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  • 24

    Feb

BMY

Bristol-Myers

$55.77

0.42 (0.76%)

07:57
02/24/17
02/24
07:57
02/24/17
07:57
Hot Stocks
Bristol-Myers' Abatacept designated as orphan treatment of IIM »

Bristol-Myers'…

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TDS

Telephone and Data

$32.72

-0.03 (-0.09%)

07:56
02/24/17
02/24
07:56
02/24/17
07:56
Earnings
Telephone and Data sees FY17 revenue $5.015B-$5.265B, consensus $5.29B »

Sees FY17 adjusted EBITDA…

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JNJ

Johnson & Johnson

$120.90

2.18 (1.84%)

07:55
02/24/17
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Hot Stocks
Janssen's Stelara designated as orphan treatment of pediatric ulcerative colitis »

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NVRO

Nevro

$94.25

-2.26 (-2.34%)

07:55
02/24/17
02/24
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07:55
Recommendations
Nevro analyst commentary  »

Nevro price target raised…

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RSPP

RSP Permian

$40.36

-0.55 (-1.34%)

07:55
02/24/17
02/24
07:55
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07:55
Conference/Events
RSP Permian to hold a special shareholder meeting »

Special Shareholder…

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ETN

Eaton

$72.12

-0.38 (-0.52%)

07:55
02/24/17
02/24
07:55
02/24/17
07:55
Conference/Events
Eaton to host analyst meeting »

Analyst meeting to be…

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TDS

Telephone and Data

$32.72

-0.03 (-0.09%)

07:54
02/24/17
02/24
07:54
02/24/17
07:54
Earnings
Telephone and Data reports Q4 EPS (5c), consensus (5c) »

Reports Q4 revenue…

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TDS

Telephone and Data

$32.72

-0.03 (-0.09%)

07:51
02/24/17
02/24
07:51
02/24/17
07:51
Hot Stocks
Telephone and Data raises quarterly dividend to 15.5c per share »

Payment will be made on…

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TERP

TerraForm Power

$11.40

-0.16 (-1.38%)

07:51
02/24/17
02/24
07:51
02/24/17
07:51
Earnings
TerraForm Power reports Q3 EPS (29c), consensus (16c) »

Reports Q3 revenue $178M,…

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SHOO

Steven Madden

07:50
02/24/17
02/24
07:50
02/24/17
07:50
Recommendations
Steven Madden analyst commentary  »

Steven Madden price…

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  • 28

    Feb

PEG

PSEG

$44.25

-0.02 (-0.05%)

07:49
02/24/17
02/24
07:49
02/24/17
07:49
Earnings
PSEG reports Q4 adjusted EPS 54c, consensus 53c »

Reports Q4 revenue…

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