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TRVN

Trevena

$6.03

0.11 (1.86%)

14:45
10/19/16
10/19
14:45
10/19/16
14:45

Meet Trevena: Pain relief drug seen having fewer adverse effects

In an exclusive interview with The Fly, Trevena's (TRVN) CEO Maxine Gowen discussed the company's Oliceridine's market opportunity and how it distinguishes itself from conventional opioids analgesics for the treatment of moderate to severe acute pain: "Oliceridine was designed specifically based on Nobel Prize winning scientific insights to try to overcome the opioid related adverse events that you see with conventional opioids. And this is incredibly important because more than fifty million patients in the U.S. are treated with an IV opioid in the hospital every year and dealing with these adverse effects can very much complicate treatment and also really impact patient safety. The innovation behind Oliceridine is that through its mechanism of action, it leverages the benefits of conventional opioids like morphine. It has the ability of delivering unparalleled pain relief, while reducing the associated nausea and vomiting, and the slowed breathing that can ultimately lead to respiratory depression and in worst case death. Our clinical data so far has shown that Oliceridine can deliver a very rapid pain relief at similar levels to morphine, but with fewer accompanying adverse events. That's what we call the widest therapeutic window, which is the margin between an effective dose and a dose which has a safety or a tolerability problem. And we really think that this should improve hospital care for patients and make it easier for physicians to treat those patients effectively." "Meet the Company" is The Fly's recurring series of exclusive short interviews with Executive Officers to offer a deeper look inside the company. The remainder of this interview to follow.

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TRVN Trevena
$6.03

0.11 (1.86%)

03/02/16
WBTH
03/02/16
INITIATION
Target $18
WBTH
Buy
Trevena initiated with a Buy at WallachBeth
WallachBeth analyst Caroline Palomeque started Trevena with a Buy rating and $18 price target. The company's lead candidate Oliceridine for post-operative acute pain may offer patients a treatment option with comparable analgesic efficacy, a faster onset of action and a more favorable safety profile than morphine, Palomeque tells investors in a research note.
03/02/16
03/02/16
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Chemical Financial (CHFC) initiated with a Strong Buy at Raymond James by analyst David Long, who believes its pending accretive merger with Talmer Bancorp (TLMR) will provide the base for a more profitable company with strengthened growth prospects. 2. Infinity Pharmaceuticals (INFI) initiated with an Outperform at FBR Capital, with analyst Christopher James saying that duvelisib has the potential to be a first-in-class treatment for specific types of blood cancers. 3. Trevena (TRVN) initiated with a Buy at WallachBeth by analyst Caroline Palomeque, who said Oliceridine may offer patients a treatment option with comparable analgesic efficiency, a faster onset of action and a more favorable safety profile than morphine. 4. Aduro Biotech (ADRO) initiated with an Outperform at FBR Capital. 5. LKQ Corp. (LKQ) initiated with a Buy at Sterne Agee CRT. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
03/29/16
FBRC
03/29/16
INITIATION
Target $16
FBRC
Outperform
Trevena initiated with an Outperform at FBR Capital
FBR Capital analyst Christopher James started Trevena with an Outperform rating and $16 price target.
05/17/16
ROTH
05/17/16
NO CHANGE
Target $14.5
ROTH
Buy
Roth Capital remains a buyer of Trevena
Roth Capital analyst Michael Higgins reiterates a Buy rating and $14.50 price target on Trevena's shares. The analyst says the company announced that its TRV027 failed in Phase 2 and will be discontinuing the program. However, given the relative risk of development between its oliceridine and its TRV027, Higgins is not making any changes to his financial models. Trevena is "well-capitalized," with cash sufficient to fund operations for two years, the analyst tells investors in a research note, adding that he sees the company's shares as being at an "attractive entry point."

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