Breaking News Instant updates and real-time market news.

LGND

Ligand

$105.75

0.21 (0.20%)

, RTRX

Retrophin

$20.08

-1.31 (-6.12%)

07:32
11/21/16
11/21
07:32
11/21/16
07:32

Ligand says Retrophin reports added 'positive' data from study of sparsentan

Ligand Pharmaceuticals (LGND) reported that its partner Retrophin (RTRX) announced additional results from the Phase 2 DUET study of sparsentan for the treatment of focal segmental glomerulosclerosis, a rare kidney disorder without an FDA-approved pharmacologic treatment that often leads to end-stage renal disease. These new findings are being presented today in the late-breaking High-Impact Clinical Trials oral session at the American Society of Nephrology Kidney Week 2016 in Chicago. As announced in September, top-line data from DUET showed the sparsentan treatment group achieved statistical significance in the study's primary efficacy endpoint, reduction of proteinuria. These results showed a greater than two-fold reduction of proteinuria compared to irbesartan, after an eight-week, double-blind treatment period. An analysis of the secondary endpoint presented today showed that a significantly greater proportion of patients receiving sparsentan achieved modified partial remission of proteinuria, compared to irbesartan-treated patients. "These new results add to the growing body of evidence from the DUET study, reinforcing our confidence that sparsentan may represent a significant advancement in the treatment of FSGS," said Stephen Aselage, CEO of Retrophin.

LGND

Ligand

$105.75

0.21 (0.20%)

RTRX

Retrophin

$20.08

-1.31 (-6.12%)

  • 21

    Nov

LGND Ligand
$105.75

0.21 (0.20%)

09/07/16
09/07/16
UPGRADE

On The Fly: Top five analyst upgrades
Catch up on today's top five analyst upgrades with this list compiled by The Fly: 1. ConocoPhillips (COP) upgraded to Hold from Underperform at Jefferies with analyst Jason Gammel citing valuation and improving financial metrics. 2. DineEquity (DIN) upgraded to Overweight from Sector Weight at KeyBanc with analyst Chris O'Cull saying the stock has reached a good entry point, while its risk/reward ratio is "compelling." 3. Gaming and Leisure Properties (GLPI) upgraded to Overweight at Morgan Stanley. 4. Aviva (AV) upgraded to Buy from Neutral at UBS with the firm saying the company is positioned to be the risk-adjusted dividend leader in the sector. 5. Ligand (LGND) upgraded to Hold from Sell at Deutsche Bank. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
10/05/16
HCWC
10/05/16
NO CHANGE
Target $160
HCWC
Buy
Ligand price target raised to $160 from $146 at H.C. Wainwright
H.C. Wainwright analyst Carol Ann Werther raised her price target for Ligand Pharmaceuticals to $160 citing three recent positive events, namely positive Phase II focal segmental glomerulosclerosis data from partner Retrophin, the beginning of a Phase II clinical trial with LGD-6972 for the treatment of type 2 diabetes and the licensing of several therapeutic programs to Seelos. Werther keeps a Buy rating on Ligand.
10/10/16
ROTH
10/10/16
NO CHANGE
Target $154
ROTH
Buy
Ligand price target raised to $154 after Carnexiv approval at Roth Capital
Roth Capital analyst Joseph Pantginis raised his price target on Ligand to $154 from $150 after partner Lundbeck announced that the FDA approved Carnexiv injection as a short-term replacement therapy for oral carbamazepine formulations in adults with certain seizure types. Ligand will receive a $1.25M milestone payment this quarter and is entitled to receive a 2.75% royalty on sales of the drug, noted Pantginis, who keeps a Buy rating on Ligand shares.
11/07/16
SPHN
11/07/16
NO CHANGE
Target $125
SPHN
Overweight
Ligand price target lowered to $125 from $150 at Stephens
Stephens analyst Drew Jones lowered his price target for Ligand to $125 from $150 on valuation. The analyst notes that the company reported mixed Q3 results as revenue softness led to lowered guidance for the year. Nonetheless, he reiterates an Overweight rating on the shares.
RTRX Retrophin
$20.08

-1.31 (-6.12%)

09/07/16
ROTH
09/07/16
NO CHANGE
Target $151
ROTH
Buy
Ligand target raised to $151 after sparsentan data at Roth Capital
Roth Capital analyst Joseph Pantginis raised his price target for Ligand Pharmaceuticals (LGND) to $151 from $149 after the company's partner Retrophin (RTRX) announced positive data from the sparsentan Phase II study in focal segmental glomerulosclerosis patients. The analyst believes the data support a potential accelerated path forward and he reminds investors that FSGS has no approved therapies. Pantginis calls the data an important win for Ligand and Retrophin. He keeps a Buy rating on Ligand. The stock is up 7% to $115.21 in early trading.
09/07/16
LEER
09/07/16
NO CHANGE
LEER
Outperform
Retrophin price target raised to $32 from $27 at Leerink
Leerink analyst Joseph Schwartz said he is "very optimistic" that sparsentan will be approved after Retrophin announced top-line results for its Phase 2b DUET study. However, he thinks it is still unclear if the results reported today will be enough to support accelerated approval or if another clinical trial will be required. Schwartz raised his price target on Retrophin to $32 from $27 following the data release and keeps an Outperform rating on the shares.
09/08/16
BMOC
09/08/16
NO CHANGE
BMOC
Retrophin price target raised to $40 from $28 at BMO Capital
BMO Capital analyst Do Kim raised the price target on Retrophin after the company reported Phase II data for its Sparsentan drug that the analyst views positively. Kim now sees a 45% chance of success for the drug, up from 25% previously. The analyst keeps an Outperform rating on the shares.
11/11/16
LEER
11/11/16
NO CHANGE
LEER
Outperform
Retrophin agreement for RE-024 bodes well for approval in 2019, says Leerink
Leerink analyst Joseph Schwartz says that the trial design for Retrophin's pending Phase 3 trial of RE-024 and the announced agreement with the FDA under the Special Protocol Assessment process for this trial bode well for potential approval in 2019. The analyst believes the company plans to initiate this trial by the end of 2016, with a drug that has shown "great promise" for the treatment of pantothenate kinase-associated neurodegeneration. He reiterates an Outperform rating on the shares.

TODAY'S FREE FLY STORIES

GS

Goldman Sachs

$249.02

1.67 (0.68%)

, TAL

TAL Education

$85.58

0.33 (0.39%)

13:51
02/27/17
02/27
13:51
02/27/17
13:51
Hot Stocks
Breaking Hot Stocks news story on Goldman Sachs, TAL Education »

Goldman Sachs reports…

GS

Goldman Sachs

$249.02

1.67 (0.68%)

TAL

TAL Education

$85.58

0.33 (0.39%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 02

    Mar

  • 03

    Mar

MYGN

Myriad Genetics

$18.98

-0.07 (-0.37%)

, VCYT

Veracyte

$7.95

0.06 (0.76%)

13:50
02/27/17
02/27
13:50
02/27/17
13:50
Recommendations
Myriad Genetics, Veracyte analyst commentary  »

Piper sees CMS halt of…

MYGN

Myriad Genetics

$18.98

-0.07 (-0.37%)

VCYT

Veracyte

$7.95

0.06 (0.76%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 01

    Mar

13:50
02/27/17
02/27
13:50
02/27/17
13:50
General news
Treasury Action: yield have spiked higher as rate hike fears flare up »

Treasury Action: yield…

LJPC

La Jolla

$19.87

1.65 (9.06%)

13:39
02/27/17
02/27
13:39
02/27/17
13:39
Recommendations
La Jolla price target raised to $40 from $27 at Jefferies »

Jefferies analyst Eun…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Feb

  • 19

    Mar

NH

NantHealth

$7.54

-0.08 (-1.05%)

, MDRX

Allscripts

$12.05

-0.11 (-0.90%)

13:33
02/27/17
02/27
13:33
02/27/17
13:33
Hot Stocks
CTCA partners with Allscripts, NantHealth to launch Clinical Pathways »

Cancer Treatment Centers…

NH

NantHealth

$7.54

-0.08 (-1.05%)

MDRX

Allscripts

$12.05

-0.11 (-0.90%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 22

    Mar

VRAY

ViewRay

$4.76

0.01 (0.21%)

13:30
02/27/17
02/27
13:30
02/27/17
13:30
Recommendations
ViewRay analyst commentary  »

ViewRay price target…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 28

    Feb

  • 06

    Mar

AIG

AIG

$63.97

0.34 (0.53%)

13:29
02/27/17
02/27
13:29
02/27/17
13:29
Periodicals
AIG board to discuss whether to penalize or oust CEO over Q4 numbers, WSJ says »

AIG's directors are…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Feb

  • 05

    Mar

HAIN

Hain Celestial

$34.61

-0.23 (-0.66%)

13:26
02/27/17
02/27
13:26
02/27/17
13:26
Options
Hain Celestial call volume above normal and directionally bullish »

Bullish option flow…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

BLUE

bluebird bio

$82.00

3.7 (4.73%)

13:19
02/27/17
02/27
13:19
02/27/17
13:19
Downgrade
bluebird bio rating change  »

Follow-up: bluebird bio…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Apr

$NSD

NASDAQ Market Internals

13:17
02/27/17
02/27
13:17
02/27/17
13:17
Technical Analysis
NASDAQ market internals summary »

Volume is average for…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

$NYE

NYSE Market Internals

13:16
02/27/17
02/27
13:16
02/27/17
13:16
Technical Analysis
NYSE market internals summary »

Volume is average for…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

BLUE

bluebird bio

$82.00

3.7 (4.73%)

13:15
02/27/17
02/27
13:15
02/27/17
13:15
Downgrade
bluebird bio rating change  »

bluebird bio downgraded…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Apr

STM

STMicroelectronics

$15.49

0.485 (3.23%)

13:06
02/27/17
02/27
13:06
02/27/17
13:06
Options
STMicroelectronics call volume above normal and directionally bullish »

Bullish option flow…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

XOM

Exxon Mobil

$81.47

0.385 (0.47%)

13:05
02/27/17
02/27
13:05
02/27/17
13:05
Periodicals
Exxon CEO sees rising Permian production, continued Russia presence, Forbes says »

Speaking in a Forbes…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 01

    Mar

  • 01

    Mar

SAFM

Sanderson Farms

$94.44

-0.72 (-0.76%)

13:01
02/27/17
02/27
13:01
02/27/17
13:01
Conference/Events
Sanderson Farms management to meet with JPMorgan »

Meeting to be held in New…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 03

    Mar

DDAIF

Daimler AG

$72.92

-0.39 (-0.53%)

13:01
02/27/17
02/27
13:01
02/27/17
13:01
Hot Stocks
Daimler names Martin Daum head of Trucks, Buses divisions »

Daimler said its…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

MMM

3M

$186.67

-0.7399 (-0.39%)

13:00
02/27/17
02/27
13:00
02/27/17
13:00
Hot Stocks
IPTAB upholds validity of 3M Korean patent »

The Intellectual Property…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

TRVG

trivago

$12.85

-0.13 (-1.00%)

12:57
02/27/17
02/27
12:57
02/27/17
12:57
Conference/Events
trivago management to meet with JPMorgan »

Meeting to be held in New…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 02

    Mar

SSNLF

Samsung

, FB

Facebook

$135.44

0.08 (0.06%)

12:55
02/27/17
02/27
12:55
02/27/17
12:55
Hot Stocks
Samsung says new Facebook app available for Samsung TVs »

Samsung (SSNLF) announced…

SSNLF

Samsung

FB

Facebook

$135.44

0.08 (0.06%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Feb

  • 28

    Feb

  • 28

    Feb

  • 06

    Mar

  • 19

    Mar

  • 28

    Mar

SNAP

Snap Inc.

12:52
02/27/17
02/27
12:52
02/27/17
12:52
Hot Stocks
Snap Inc: Some Class A shares subject to separate lock-up »

In an amended IPO…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 02

    Mar

MRVL

Marvell

12:51
02/27/17
02/27
12:51
02/27/17
12:51
Options
Notable premium seller in Marvell Tech »

Notable premium seller in…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Feb

  • 10

    Mar

  • 04

    Apr

  • 05

    Apr

WLL

Whiting Petroleum

$10.95

0.15 (1.39%)

12:46
02/27/17
02/27
12:46
02/27/17
12:46
Options
Whiting Petroleum call volume above normal and directionally bullish »

Bullish option flow…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 01

    Mar

CLSD

Clearside Biomedical

$8.06

1.16 (16.81%)

12:45
02/27/17
02/27
12:45
02/27/17
12:45
Conference/Events
Clearside Biomedical has a conference call hosted by JPMorgan »

JPMorgan Analyst Rama…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Feb

SBGSY

Schneider Electric

$13.49

-0.21 (-1.53%)

12:44
02/27/17
02/27
12:44
02/27/17
12:44
Conference/Events
Schneider Electric management to meet with JPMorgan »

Meetings to be held in…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Feb

  • 02

    Mar

  • 03

    Mar

MTB

M&T Bank

$168.14

-0.535 (-0.32%)

12:37
02/27/17
02/27
12:37
02/27/17
12:37
Hot Stocks
M&T Bank announces passing of COO Mark Czarnecki »

M&T Bank announced…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

Get Full Fly Access

Breaking market intelligence sent straight to you
Our team of experts analyze every news story and filter out the noise to deliver real-time market moving news.
Up-to-date information on important industry events
Get real-time updates on events that are moving the market—from conferences and calls to syndicate announcements.
News focused on the companies in your portfolio
Create up to 12 portfolios with 150 stocks each, and see how active they are in market news.