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NK

NantKwest

$7.55

-0.04 (-0.53%)

11:45
11/22/16
11/22
11:45
11/22/16
11:45

NantKwest says next gen NK Cell therapy poised to transition into human trials

NantKwest announced in a paper published in the journal Oncotarget results of a research study conducted at the National Cancer Institute in collaboration with scientists at NantKwest and NantCell. In this research study, aNK cells, lacking CD16, were engineered to express the high affinity CD16 receptor and further engineered to express IL-2. These high affinity NK cells have been shown in previous studies to enhanced perforin and granzyme-mediated killing of tumor cells, as well as support the expansion of NK cell populations. Study results showed high levels of granzyme activity in haNK cells and demonstrated the effects of irradiation on haNK cell in multiple phenotypic markers, viability, IL-2 production, and cell killing in a wide range of human tumor cells. The study also compared endogenous irradiated haNK cell killing of tumor cells with that of irradiated haNK-mediated ADCC using cetuximab, trastuzumab and pertuzumab monoclonal antibodies. Patrick Soon-Shiong, MD, PhD, Chairman and CEO of NantKwest and a co-senior author on the paper said: "Ongoing preclinical studies using haNK cell therapy in combination with antibody therapy offer the promising potential to enhance the clinical efficacy of either agent alone and become a part of the standard-of-care for cancer patients. With this foundational data in place, we on now focused on rapidly transitioning our haNK program into human clinical trials over the next few months."

  • 29

    Nov

  • 03

    Dec

NK NantKwest
$7.55

-0.04 (-0.53%)

12/22/15
ADAM
12/22/15
INITIATION
Target $20
ADAM
Buy
NantKwest initiated with a Buy at Canaccord
Canaccord analyst Arlinda Lee initiated NantKwest with a Buy rating and $20 price target on shares.
12/22/15
12/22/15
INITIATION

On The Fly: Analyst Initiation Summary
Today's noteworthy initiations include: AVANGRID (AGR) initiated with a Neutral at JPMorgan... Accuray (ARAY) initiated with a Sector Perform at RBC Capital... American Express (AXP) initiated with a Market Perform at JMP Securities... BioTime (BTX) initiated with an Outperform at Oppenheimer... Biota Pharmaceuticals (BOTA) initiated with an Outperform at FBR Capital... Box (BOX) initiated with an Outperform at JMP Securities... CNO Financial (CNO) initiated with an Outperform at Raymond James... Capital One (COF) initiated with a Hold at Evercore ISI... Criteo (CRTO) initiated with a Buy at SunTrust... CyberArk (CYBR) initiated with a Hold at Evercore ISI... CyrusOne (CONE) initiated with an Overweight at JPMorgan... Digital Realty (DLR) initiated with a Neutral at JPMorgan... Discover (DFS) initiated with a Hold at Evercore ISI... Etsy (ETSY) initiated with a Sell at Roth Capital... Fenix Parts (FENX) initiated with a Buy at Roth Capital... Fibrocell Science (FCSC) initiated with a Buy at Roth Capital... Franklin Electric (FELE) initiated with a Sell at Ladenburg... Harman (HAR) initiated with a Neutral at Susquehanna... Karyopharm (KPTI) initiated with a Buy at Canaccord... MPLX (MPLX) initiated with a Neutral at Credit Suisse... Marchex (MCHX) initiated with a Buy at Roth Capital... NantKwest (NK) initiated with a Buy at Canaccord... Nexstar (NXST) initiated with an Outperform at Barrington... Orbital ATK (OA) initiated with a Buy at CL King... Perrigo (PRGO) initiated with an Outperform at Northland... QTS Realty Trust (QTS) initiated with an Overweight at JPMorgan... RPC, Inc. (RES) initiated with a Buy at Guggenheim... Rubicon Project (RUBI) initiated with a Buy at SunTrust... Sorrento Therapeutics (SRNE) initiated with an Outperform at FBR Capital... Travelport (TVPT) initiated with a Neutral at SunTrust... TubeMogul (TUBE) initiated with a Buy at SunTrust... Ultragenyx (RARE) initiated with a Buy at Canaccord... Varian Medical (VAR) initiated with a Sector Perform at RBC Capital... Wayfair (W) initiated with a Neutral at SunTrust... Xencor (XNCR) initiated with a Buy at Canaccord.
06/02/16
RAJA
06/02/16
INITIATION
RAJA
Market Perform
NantKwest initiated with a Market Perform at Raymond James

TODAY'S FREE FLY STORIES

02:35
09/26/17
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02:35
General news
FX Update: USD-JPY tumbled to around 111.50 »

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GNCA

Genocea

$5.33

0.04 (0.76%)

20:43
09/25/17
09/25
20:43
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20:43
Downgrade
Genocea rating change at Stifel »

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CQH

Cheniere Energy Partners LP

$24.66

0.27 (1.11%)

20:27
09/25/17
09/25
20:27
09/25/17
20:27
Initiation
Cheniere Energy Partners LP initiated at BMO Capital »

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DAL

Delta Air Lines

$48.32

-0.15 (-0.31%)

20:25
09/25/17
09/25
20:25
09/25/17
20:25
Initiation
Delta Air Lines initiated at Macquarie »

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HA

Hawaiian Holdings

$37.45

-0.25 (-0.66%)

20:25
09/25/17
09/25
20:25
09/25/17
20:25
Initiation
Hawaiian Holdings initiated at Macquarie »

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  • 28

    Sep

ALK

Alaska Air

$74.79

0.04 (0.05%)

20:25
09/25/17
09/25
20:25
09/25/17
20:25
Initiation
Alaska Air initiated at Macquarie »

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LUV

Southwest

$55.12

0.19 (0.35%)

20:25
09/25/17
09/25
20:25
09/25/17
20:25
Initiation
Southwest initiated at Macquarie »

Southwest initiated with…

03/08/13
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03/08/13
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03/06/13
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DRI

Darden

$83.14

0.26 (0.31%)

, FDS

FactSet

$170.81

2.2 (1.30%)

20:25
09/25/17
09/25
20:25
09/25/17
20:25
Earnings
Notable companies reporting before tomorrow's open »

Notable companies…

DRI

Darden

$83.14

0.26 (0.31%)

FDS

FactSet

$170.81

2.2 (1.30%)

03/08/13
Wedge Partners
03/08/13
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03/06/13
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03/06/13
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  • 26

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SAVE

Spirit Airlines

$34.15

0.44 (1.31%)

20:22
09/25/17
09/25
20:22
09/25/17
20:22
Initiation
Spirit Airlines initiated at Macquarie »

Spirit Airlines initiated…

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  • 27

    Sep

JBLU

JetBlue

$18.87

0.25 (1.34%)

20:22
09/25/17
09/25
20:22
09/25/17
20:22
Initiation
JetBlue initiated at Macquarie »

JetBlue initiated with a…

03/08/13
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03/08/13
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03/06/13
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ALGT

Allegiant Travel

$133.95

3.85 (2.96%)

20:22
09/25/17
09/25
20:22
09/25/17
20:22
Initiation
Allegiant Travel initiated at Macquarie »

Allegiant Travel…

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  • 26

    Sep

AAL

American Airlines

$47.70

0.64 (1.36%)

20:22
09/25/17
09/25
20:22
09/25/17
20:22
Initiation
American Airlines initiated at Macquarie »

American Airlines…

03/08/13
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  • 02

    Oct

UAL

United Continental

$59.44

0.64 (1.09%)

20:21
09/25/17
09/25
20:21
09/25/17
20:21
Initiation
United Continental initiated at Macquarie »

United Continental…

03/08/13
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  • 02

    Oct

LUV

Southwest

$55.12

0.19 (0.35%)

20:10
09/25/17
09/25
20:10
09/25/17
20:10
Initiation
Southwest initiated at Macquarie »

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03/08/13
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AMPH

Amphastar

$16.27

0.17 (1.06%)

, AVDL

Avadel Pharmaceuticals

$9.45

-0.16 (-1.66%)

18:59
09/25/17
09/25
18:59
09/25/17
18:59
Hot Stocks
Amphastar announces FDA approval of Neostigmine Methylsulfate Injection, USP »

Amphastar (AMPH)…

AMPH

Amphastar

$16.27

0.17 (1.06%)

AVDL

Avadel Pharmaceuticals

$9.45

-0.16 (-1.66%)

03/08/13
Wedge Partners
03/08/13
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03/06/13
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03/06/13
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ACN

Accenture

$138.16

0.26 (0.19%)

18:58
09/25/17
09/25
18:58
09/25/17
18:58
Hot Stocks
Accenture chief marketing & communications officer Taylor to retire Aug 31, 2018 »

Accenture announced that…

03/08/13
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SPR

Spirit AeroSystems

$78.07

-0.38 (-0.48%)

, BA

Boeing

$254.32

-2.13 (-0.83%)

18:31
09/25/17
09/25
18:31
09/25/17
18:31
Hot Stocks
Spirit AeroSystems finalizes agreement with Boeing »

Spirit AeroSystems (SPR)…

SPR

Spirit AeroSystems

$78.07

-0.38 (-0.48%)

BA

Boeing

$254.32

-2.13 (-0.83%)

03/08/13
Wedge Partners
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  • 25

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MOH

Molina Healthcare

$64.54

-0.78 (-1.19%)

, UNH

UnitedHealth

$191.75

-1.28 (-0.66%)

18:17
09/25/17
09/25
18:17
09/25/17
18:17
Hot Stocks
Senator Collins opposes Graham-Cassidy ACA repeal bill »

U.S. Senator Susan…

MOH

Molina Healthcare

$64.54

-0.78 (-1.19%)

UNH

UnitedHealth

$191.75

-1.28 (-0.66%)

CNC

Centene

$90.33

-1.89 (-2.05%)

WCG

WellCare

$164.15

-3.01 (-1.80%)

CI

Cigna

$181.44

-1.3 (-0.71%)

ANTM

Anthem

$181.50

-1.36 (-0.74%)

HNT

Health Net

HUM

Humana

$237.21

-1.88 (-0.79%)

AET

Aetna

$151.98

-1.59 (-1.04%)

03/08/13
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  • 26

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  • 08

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18:15
09/25/17
09/25
18:15
09/25/17
18:15
General news
Breaking General news story  »

Minneapolis Federal…

CATM

Cardtronics

$26.10

-3.17 (-10.83%)

18:13
09/25/17
09/25
18:13
09/25/17
18:13
Downgrade
Cardtronics rating change at William Blair »

Cardtronics downgraded to…

03/08/13
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IVTY

Invuity

$7.80

-0.5 (-6.02%)

18:10
09/25/17
09/25
18:10
09/25/17
18:10
Recommendations
Invuity analyst commentary at Piper Jaffray »

Invuity's…

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  • 25

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  • 16

    Nov

MOH

Molina Healthcare

$64.54

-0.78 (-1.19%)

, UNH

UnitedHealth

$191.75

-1.28 (-0.66%)

18:05
09/25/17
09/25
18:05
09/25/17
18:05
Hot Stocks
CBO: Graham-Cassidy ACA repeal bill to reduce number of insured by 'millions' »

The Congressional Budget…

MOH

Molina Healthcare

$64.54

-0.78 (-1.19%)

UNH

UnitedHealth

$191.75

-1.28 (-0.66%)

CNC

Centene

$90.33

-1.89 (-2.05%)

WCG

WellCare

$164.15

-3.01 (-1.80%)

CI

Cigna

$181.44

-1.3 (-0.71%)

ANTM

Anthem

$181.50

-1.36 (-0.74%)

HNT

Health Net

HUM

Humana

$237.21

-1.88 (-0.79%)

AET

Aetna

$151.98

-1.59 (-1.04%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
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  • 26

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  • 08

    Nov

GPC

Genuine Parts

$93.22

5.24 (5.96%)

18:04
09/25/17
09/25
18:04
09/25/17
18:04
Recommendations
Genuine Parts analyst commentary at RBC Capital »

Genuine Parts acquisition…

03/08/13
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AA

Alcoa

$45.29

-0.09 (-0.20%)

, FCX

Freeport McMoRan

$13.89

-0.17 (-1.21%)

17:55
09/25/17
09/25
17:55
09/25/17
17:55
Recommendations
Alcoa, Freeport McMoRan, Teck Resources, Newmont Mining, Warrior Met Coal, Cleveland-Cliffs analyst commentary at Morgan Stanley »

Morgan Stanley raising…

AA

Alcoa

$45.29

-0.09 (-0.20%)

FCX

Freeport McMoRan

$13.89

-0.17 (-1.21%)

TECK

Teck Resources

$21.24

-0.72 (-3.28%)

NEM

Newmont Mining

$38.63

0.74 (1.95%)

HCC

Warrior Met Coal

$24.11

0.76 (3.25%)

CLF

Cleveland-Cliffs

03/08/13
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03/08/13
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03/06/13
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03/06/13
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17:55
09/25/17
09/25
17:55
09/25/17
17:55
Conference/Events
Federal Reserve Bank of Minneapolis President participates in a discussion »

Minneapolis Federal…

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