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NK

NantKwest

$7.55

-0.04 (-0.53%)

11:45
11/22/16
11/22
11:45
11/22/16
11:45

NantKwest says next gen NK Cell therapy poised to transition into human trials

NantKwest announced in a paper published in the journal Oncotarget results of a research study conducted at the National Cancer Institute in collaboration with scientists at NantKwest and NantCell. In this research study, aNK cells, lacking CD16, were engineered to express the high affinity CD16 receptor and further engineered to express IL-2. These high affinity NK cells have been shown in previous studies to enhanced perforin and granzyme-mediated killing of tumor cells, as well as support the expansion of NK cell populations. Study results showed high levels of granzyme activity in haNK cells and demonstrated the effects of irradiation on haNK cell in multiple phenotypic markers, viability, IL-2 production, and cell killing in a wide range of human tumor cells. The study also compared endogenous irradiated haNK cell killing of tumor cells with that of irradiated haNK-mediated ADCC using cetuximab, trastuzumab and pertuzumab monoclonal antibodies. Patrick Soon-Shiong, MD, PhD, Chairman and CEO of NantKwest and a co-senior author on the paper said: "Ongoing preclinical studies using haNK cell therapy in combination with antibody therapy offer the promising potential to enhance the clinical efficacy of either agent alone and become a part of the standard-of-care for cancer patients. With this foundational data in place, we on now focused on rapidly transitioning our haNK program into human clinical trials over the next few months."

  • 29

    Nov

  • 03

    Dec

NK NantKwest
$7.55

-0.04 (-0.53%)

12/22/15
ADAM
12/22/15
INITIATION
Target $20
ADAM
Buy
NantKwest initiated with a Buy at Canaccord
Canaccord analyst Arlinda Lee initiated NantKwest with a Buy rating and $20 price target on shares.
12/22/15
12/22/15
INITIATION

On The Fly: Analyst Initiation Summary
Today's noteworthy initiations include: AVANGRID (AGR) initiated with a Neutral at JPMorgan... Accuray (ARAY) initiated with a Sector Perform at RBC Capital... American Express (AXP) initiated with a Market Perform at JMP Securities... BioTime (BTX) initiated with an Outperform at Oppenheimer... Biota Pharmaceuticals (BOTA) initiated with an Outperform at FBR Capital... Box (BOX) initiated with an Outperform at JMP Securities... CNO Financial (CNO) initiated with an Outperform at Raymond James... Capital One (COF) initiated with a Hold at Evercore ISI... Criteo (CRTO) initiated with a Buy at SunTrust... CyberArk (CYBR) initiated with a Hold at Evercore ISI... CyrusOne (CONE) initiated with an Overweight at JPMorgan... Digital Realty (DLR) initiated with a Neutral at JPMorgan... Discover (DFS) initiated with a Hold at Evercore ISI... Etsy (ETSY) initiated with a Sell at Roth Capital... Fenix Parts (FENX) initiated with a Buy at Roth Capital... Fibrocell Science (FCSC) initiated with a Buy at Roth Capital... Franklin Electric (FELE) initiated with a Sell at Ladenburg... Harman (HAR) initiated with a Neutral at Susquehanna... Karyopharm (KPTI) initiated with a Buy at Canaccord... MPLX (MPLX) initiated with a Neutral at Credit Suisse... Marchex (MCHX) initiated with a Buy at Roth Capital... NantKwest (NK) initiated with a Buy at Canaccord... Nexstar (NXST) initiated with an Outperform at Barrington... Orbital ATK (OA) initiated with a Buy at CL King... Perrigo (PRGO) initiated with an Outperform at Northland... QTS Realty Trust (QTS) initiated with an Overweight at JPMorgan... RPC, Inc. (RES) initiated with a Buy at Guggenheim... Rubicon Project (RUBI) initiated with a Buy at SunTrust... Sorrento Therapeutics (SRNE) initiated with an Outperform at FBR Capital... Travelport (TVPT) initiated with a Neutral at SunTrust... TubeMogul (TUBE) initiated with a Buy at SunTrust... Ultragenyx (RARE) initiated with a Buy at Canaccord... Varian Medical (VAR) initiated with a Sector Perform at RBC Capital... Wayfair (W) initiated with a Neutral at SunTrust... Xencor (XNCR) initiated with a Buy at Canaccord.
06/02/16
RAJA
06/02/16
INITIATION
RAJA
Market Perform
NantKwest initiated with a Market Perform at Raymond James

TODAY'S FREE FLY STORIES

CLC

Clarcor

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Parker-Hannifin

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ASUR

Asure Software

$8.48

0.21 (2.54%)

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  • 12

    Dec

BDC

Belden

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12/05/16
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Earnings
Belden sees FY16 adjusted EPS $5.20-$5.30, consensus $5.24 »

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  • 05

    Dec

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General news
Chicago Fed dove Evans sees growth picking up »

Chicago Fed dove Evans…

BDC

Belden

09:29
12/05/16
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Earnings
Belden sees Q4 adjusted EPS $1.36-$1.46, consensus $1.40 »

Sees Q4 revenue…

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  • 05

    Dec

BDC

Belden

09:28
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Hot Stocks
Breaking Hot Stocks news story on Belden »

Belden to confirm Q4,…

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  • 05

    Dec

INWK

InnerWorkings

$9.20

0.25 (2.79%)

09:28
12/05/16
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InnerWorkings, GateHouse Media announce multi-year affiliation »

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  • 14

    Dec

STC

Stewart

09:28
12/05/16
12/05
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09:28
Downgrade
Stewart rating change  »

Stewart downgraded to…

03/08/13
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MEET

MeetMe

09:27
12/05/16
12/05
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Earnings
MeetMe sees FY revenue $74.5M-$76M, consensus $75.11M »

Adjusted EBITDA for the…

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  • 05

    Dec

OPTT

Ocean Power

$3.23

0.04 (1.25%)

09:27
12/05/16
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Hot Stocks
Ocean Power, Sonalysts announce joint marketing agreement »

Ocean Power Technologies…

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GIMO

Gigamon

, VZ

Verizon

09:27
12/05/16
12/05
09:27
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09:27
Recommendations
Gigamon, Verizon, AT&T, T-Mobile, Amazon.com analyst commentary  »

Gigamon setting up well…

GIMO

Gigamon

VZ

Verizon

T

AT&T

TMUS

T-Mobile

$54.44

0.18 (0.33%)

AMZN

Amazon.com

$740.34

-3.31 (-0.45%)

03/08/13
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  • 05

    Dec

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    Dec

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    Dec

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    Dec

  • 24

    Jan

MEET

MeetMe

09:27
12/05/16
12/05
09:27
12/05/16
09:27
Earnings
MeetMe sees Q4 revenue $27.5M-$29M, consensus $28.2M »

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03/08/13
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  • 05

    Dec

MOS

Mosaic

09:26
12/05/16
12/05
09:26
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09:26
Recommendations
Mosaic analyst commentary  »

Mosaic estimates lowered…

03/08/13
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MEET

MeetMe

09:26
12/05/16
12/05
09:26
12/05/16
09:26
Hot Stocks
MeetMe reports U.S. mobile CPMs up 14% y/y in November »

MeetMe said that its…

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  • 05

    Dec

MEET

MeetMe

09:26
12/05/16
12/05
09:26
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09:26
Hot Stocks
Breaking Hot Stocks news story on MeetMe »

MeetMe reiterates Q4, FY…

03/08/13
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  • 05

    Dec

MCD

McDonald's

09:26
12/05/16
12/05
09:26
12/05/16
09:26
Technical Analysis
McDonald's extends its recent recovery »

The stock was last at…

03/08/13
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FRP

FairPoint

$17.00

0.25 (1.49%)

, CNSL

Consolidated Communications

$28.38

0.11 (0.39%)

09:25
12/05/16
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Hot Stocks
On The Fly: Pre-market Movers »

FairPoint Communications…

FRP

FairPoint

$17.00

0.25 (1.49%)

CNSL

Consolidated Communications

$28.38

0.11 (0.39%)

CHK

Chesapeake

BLCM

Bellicum Pharmaceuticals

$18.72

1.74 (10.25%)

MRVL

Marvell

$14.02

0.04 (0.29%)

KITE

Kite Pharma

$50.76

0.04 (0.08%)

CERC

Cerecor

$1.75

-0.24 (-12.06%)

ETP

Energy Transfer Partners

03/08/13
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  • 05

    Dec

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    Dec

ICE

IntercontinentalExchange

09:25
12/05/16
12/05
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09:25
Hot Stocks
IntercontinentalExchange reports November futures ADV up 12% »

Intercontinental Exchange…

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  • 06

    Dec

QURE

uniQure

$5.68

-0.31 (-5.18%)

09:25
12/05/16
12/05
09:25
12/05/16
09:25
Conference/Events
uniQure to host investor breakfast meeting »

Investor breakfast…

03/08/13
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  • 05

    Dec

  • 08

    Dec

BSFT

BroadSoft

$40.30

-0.35 (-0.86%)

09:25
12/05/16
12/05
09:25
12/05/16
09:25
Conference/Events
BroadSoft to host investor day »

Investor Day to be held…

03/08/13
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  • 05

    Dec

SSNLF

Samsung

09:23
12/05/16
12/05
09:23
12/05/16
09:23
Conference/Events
Samsung management to meet with JPMorgan »

Meetings to be held in…

03/08/13
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03/06/13
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  • 05

    Dec

  • 06

    Dec

  • 07

    Dec

  • 08

    Dec

NEM

Newmont Mining

09:22
12/05/16
12/05
09:22
12/05/16
09:22
Technical Analysis
Newmont Mining falls in pre-market »

The shares were last down…

03/08/13
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03/08/13
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03/06/13
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03/06/13
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MSCC

Microsemi

$52.95

0.32 (0.61%)

, INTC

Intel

$34.16

0.4 (1.18%)

09:22
12/05/16
12/05
09:22
12/05/16
09:22
Recommendations
Microsemi, Intel analyst commentary  »

Microsemi price target…

MSCC

Microsemi

$52.95

0.32 (0.61%)

INTC

Intel

$34.16

0.4 (1.18%)

03/08/13
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03/08/13
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03/06/13
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  • 05

    Dec

  • 07

    Dec

  • 14

    Dec

  • 14

    Feb

09:21
12/05/16
12/05
09:21
12/05/16
09:21
Conference/Events
Stifel electrical equipment analysts to hold a luncheon meeting »

Electrical, Networking…

AMRC

Amerseco

09:20
12/05/16
12/05
09:20
12/05/16
09:20
Hot Stocks
Amerseco, Town of Sturbridge partner to build 2.4 MW Community Solar Array »

Ameresco announced the…

03/08/13
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03/08/13
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03/06/13
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03/06/13
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  • 07

    Dec

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    Dec

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