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NK

NantKwest

$7.55

-0.04 (-0.53%)

11:45
11/22/16
11/22
11:45
11/22/16
11:45

NantKwest says next gen NK Cell therapy poised to transition into human trials

NantKwest announced in a paper published in the journal Oncotarget results of a research study conducted at the National Cancer Institute in collaboration with scientists at NantKwest and NantCell. In this research study, aNK cells, lacking CD16, were engineered to express the high affinity CD16 receptor and further engineered to express IL-2. These high affinity NK cells have been shown in previous studies to enhanced perforin and granzyme-mediated killing of tumor cells, as well as support the expansion of NK cell populations. Study results showed high levels of granzyme activity in haNK cells and demonstrated the effects of irradiation on haNK cell in multiple phenotypic markers, viability, IL-2 production, and cell killing in a wide range of human tumor cells. The study also compared endogenous irradiated haNK cell killing of tumor cells with that of irradiated haNK-mediated ADCC using cetuximab, trastuzumab and pertuzumab monoclonal antibodies. Patrick Soon-Shiong, MD, PhD, Chairman and CEO of NantKwest and a co-senior author on the paper said: "Ongoing preclinical studies using haNK cell therapy in combination with antibody therapy offer the promising potential to enhance the clinical efficacy of either agent alone and become a part of the standard-of-care for cancer patients. With this foundational data in place, we on now focused on rapidly transitioning our haNK program into human clinical trials over the next few months."

  • 29

    Nov

  • 03

    Dec

NK NantKwest
$7.55

-0.04 (-0.53%)

12/22/15
ADAM
12/22/15
INITIATION
Target $20
ADAM
Buy
NantKwest initiated with a Buy at Canaccord
Canaccord analyst Arlinda Lee initiated NantKwest with a Buy rating and $20 price target on shares.
12/22/15
12/22/15
INITIATION

On The Fly: Analyst Initiation Summary
Today's noteworthy initiations include: AVANGRID (AGR) initiated with a Neutral at JPMorgan... Accuray (ARAY) initiated with a Sector Perform at RBC Capital... American Express (AXP) initiated with a Market Perform at JMP Securities... BioTime (BTX) initiated with an Outperform at Oppenheimer... Biota Pharmaceuticals (BOTA) initiated with an Outperform at FBR Capital... Box (BOX) initiated with an Outperform at JMP Securities... CNO Financial (CNO) initiated with an Outperform at Raymond James... Capital One (COF) initiated with a Hold at Evercore ISI... Criteo (CRTO) initiated with a Buy at SunTrust... CyberArk (CYBR) initiated with a Hold at Evercore ISI... CyrusOne (CONE) initiated with an Overweight at JPMorgan... Digital Realty (DLR) initiated with a Neutral at JPMorgan... Discover (DFS) initiated with a Hold at Evercore ISI... Etsy (ETSY) initiated with a Sell at Roth Capital... Fenix Parts (FENX) initiated with a Buy at Roth Capital... Fibrocell Science (FCSC) initiated with a Buy at Roth Capital... Franklin Electric (FELE) initiated with a Sell at Ladenburg... Harman (HAR) initiated with a Neutral at Susquehanna... Karyopharm (KPTI) initiated with a Buy at Canaccord... MPLX (MPLX) initiated with a Neutral at Credit Suisse... Marchex (MCHX) initiated with a Buy at Roth Capital... NantKwest (NK) initiated with a Buy at Canaccord... Nexstar (NXST) initiated with an Outperform at Barrington... Orbital ATK (OA) initiated with a Buy at CL King... Perrigo (PRGO) initiated with an Outperform at Northland... QTS Realty Trust (QTS) initiated with an Overweight at JPMorgan... RPC, Inc. (RES) initiated with a Buy at Guggenheim... Rubicon Project (RUBI) initiated with a Buy at SunTrust... Sorrento Therapeutics (SRNE) initiated with an Outperform at FBR Capital... Travelport (TVPT) initiated with a Neutral at SunTrust... TubeMogul (TUBE) initiated with a Buy at SunTrust... Ultragenyx (RARE) initiated with a Buy at Canaccord... Varian Medical (VAR) initiated with a Sector Perform at RBC Capital... Wayfair (W) initiated with a Neutral at SunTrust... Xencor (XNCR) initiated with a Buy at Canaccord.
06/02/16
RAJA
06/02/16
INITIATION
RAJA
Market Perform
NantKwest initiated with a Market Perform at Raymond James

TODAY'S FREE FLY STORIES

AMTD

TD Ameritrade

$43.41

-0.07 (-0.16%)

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02/27/17
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10:50
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General news
U.S. Dallas Fed manufacturing index rose 2.4 points to 24.5 in February »

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HBI

Hanesbrands

$20.60

-0.78 (-3.65%)

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  • 01

    Mar

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Dallas Federal Reserve…

SPKE

Spark Energy

$27.25

1.7 (6.65%)

10:44
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02/27
10:44
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10:44
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Spark Energy analyst commentary  »

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  • 09

    Mar

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Dallas Fed Mfg Survey Production Index data reported »

February Dallas Fed Mfg…

UPS

UPS

$105.88

-0.3 (-0.28%)

10:41
02/27/17
02/27
10:41
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10:41
Options
Opening action in UPS downside puts »

Opening action in UPS…

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  • 19

    Mar

10:37
02/27/17
02/27
10:37
02/27/17
10:37
General news
Dallas Fed Mfg Survey Production Index data reported »

February Dallas Fed Mfg…

TVPT

Travelport

$12.88

-0.06 (-0.46%)

10:33
02/27/17
02/27
10:33
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10:33
Conference/Events
Travelport management to meet with Evercore ISI »

Meeting to be held in San…

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  • 01

    Mar

PGNX

Progenics

$10.36

0.12 (1.17%)

10:32
02/27/17
02/27
10:32
02/27/17
10:32
Conference/Events
Progenics management to meet with Aegis »

Meeting to be held in New…

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  • 01

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    Mar

ORIT

Oritani Financial

$17.15

-0.05 (-0.29%)

10:31
02/27/17
02/27
10:31
02/27/17
10:31
Conference/Events
Oritani Financial management to meet with Sandler O'Neill »

Meetings to be held in…

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  • 01

    Mar

  • 02

    Mar

  • 15

    May

X

U.S. Steel

$37.37

0.355 (0.96%)

10:31
02/27/17
02/27
10:31
02/27/17
10:31
Options
Bullish short-term option play in US Steel as shares see strength »

Bullish short-term option…

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VIP

VimpelCom

$4.30

-0.04 (-0.92%)

10:30
02/27/17
02/27
10:30
02/27/17
10:30
Earnings
VimpelCom reports Q4 EBITDA $783M »

Reports Q4 revenue…

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MMS

Maximus

$60.41

0.1049 (0.17%)

10:30
02/27/17
02/27
10:30
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Conference/Events
Maximus management to meet with Maxim »

Meetings to be held in…

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  • 27

    Feb

  • 01

    Mar

  • 02

    Mar

10:29
02/27/17
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10:29
02/27/17
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General news
Market little changed in early trading as investors await Trump address »

Stock futures drifted…

CTSO

CytoSorbents

$5.60

0.05 (0.90%)

10:28
02/27/17
02/27
10:28
02/27/17
10:28
Conference/Events
CytoSorbents management to meet with B. Riley »

Meeting to be held in New…

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  • 01

    Mar

  • 03

    Mar

VIP

VimpelCom

$4.30

-0.04 (-0.92%)

10:27
02/27/17
02/27
10:27
02/27/17
10:27
Hot Stocks
VimpelCom introduces new dividend policy »

VimpelCom introduces a…

03/08/13
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CL

Colgate-Palmolive

$72.93

-0.42 (-0.57%)

10:26
02/27/17
02/27
10:26
02/27/17
10:26
Options
Colgate Palmolive call volume above normal and directionally bullish »

Bullish option flow…

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BP

BP

$33.77

0.265 (0.79%)

10:25
02/27/17
02/27
10:25
02/27/17
10:25
Conference/Events
BP management to meet with Jefferies »

Meeting to be held in…

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  • 01

    Mar

  • 06

    Mar

10:25
02/27/17
02/27
10:25
02/27/17
10:25
General news
Treasury Action: yields remained above lows »

Treasury Action: yields…

BAH

Booz Allen

$36.13

0.205 (0.57%)

10:24
02/27/17
02/27
10:24
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10:24
Conference/Events
Booz Allen management to meet with Drexel Hamilton »

Meeting to be held in…

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  • 01

    Mar

VCYT

Veracyte

$7.95

0.06 (0.76%)

10:23
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Veracyte: Data show potential for non-invasive test to improve cancer diagnosis »

Veracyte announced that…

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  • 01

    Mar

AXP

American Express

$79.75

-0.01 (-0.01%)

, GOOG

Alphabet

$828.64

-2.69 (-0.32%)

10:23
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Hot Stocks
American Express says doesn't have a 'deep' partnership with Google right now »

Says Marriott (MAR) has…

AXP

American Express

$79.75

-0.01 (-0.01%)

GOOG

Alphabet

$828.64

-2.69 (-0.32%)

MAR

Marriott

$87.08

0.08 (0.09%)

HOT

Starwood

03/08/13
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  • 27

    Feb

  • 27

    Feb

  • 06

    Mar

  • 19

    Mar

AAN

Aaron's

$27.23

0.05 (0.18%)

10:22
02/27/17
02/27
10:22
02/27/17
10:22
Conference/Events
Aaron's management to meet with Jefferies »

Meetings to be held in…

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  • 28

    Feb

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