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OSIR

Osiris

$6.43

-0.11 (-1.68%)

17:03
11/22/16
11/22
17:03
11/22/16
17:03

Osiris says all wounds reached complete closure in Grafix effectiveness review

Osiris Therapeutics announced that a new peer-reviewed manuscript by physician and surgeon Jonathan Smedley, DPM, FACFAS, entitled "Wound Closure in Smoking Peripheral Arterial Disease Patients with Treatment Refractory Ulcerations: A 12-month Follow-up Case Series," has been published in the International Journal of Lower Extremity Wounds and is available on-line. A 1-year, single-center effectiveness review was conducted on the clinical outcomes in actively smoking peripheral arterial disease patients treated with Grafix(R) for use in the treatment of refractory lower extremity ulcerations. Wound types included chronic ischemic and neuroischemic ulcerations and wounds of mixed venous and arterial etiology. Wounds were characterized by an average size of 4.6 cm2 and a previous duration of 53 weeks with a failure to respond to standard of care and other advanced treatment measures. 80% of the patients were diabetic. Daily cigarette consumption for the patients ranged from 1/2 pack to greater than 1 pack per day, and the mean ankle brachial index for the group was 0.7. More than half of the patients were not candidates for revascularization procedures. Study Outcomes: all wounds reached complete closure and remained closed at the 12-month follow up; the mean time to closure was 7.8 weeks with a mean graft use of 7.0 grafts; the mean 4-week percentage of wound area reduction was 69.4%; there were no adverse events attributed to the use of Grafix. "Patients often times present with a variety of comorbid conditions that pose challenges to wound care providers. Some refractory wounds persist despite long term multidisciplinary efforts to promote timely closure. Options such as Grafix allow us to pursue management of these lower extremity ulcerations to the point of resolution. This is extremely valuable, especially in the high-risk diabetic population," said Dr. Smedley.

OSIR Osiris
$6.43

-0.11 (-1.68%)

05/16/16
PIPR
05/16/16
NO CHANGE
Target $12
PIPR
Overweight
Osiris accounting issues still 'plague' story, says Piper Jaffray
Piper Jaffray analyst Edward Tenthoff lowered his price target for Osiris Therapeutics to $12 from $18.50 after the company missed its 2015 annual filing deadline. Accounting issues continue to "plague the Osiris story," Tenthoff tells investors in a research note. He keeps an Overweight rating on the shares.
05/17/16
PIPR
05/17/16
NO CHANGE
Target $12
PIPR
Overweight
Osiris false claims lawsuit another overhang, says Piper Jaffray
After MiMedx (MDXG) announced that it has filed suit against Osiris (OSIR), asserting that Osiris "knowingly and willfully made false and misleading representations," Piper Jaffray analyst Edward Tenthoff said it is unclear at this time what merit the claims have, but added that the lawsuit represents "yet another" overhang for Osiris shares. Noting that he expects BioSurgery sales to return Osiris to profitability, Tenthoff maintains an Overweight rating and $12 price target on the stock.
06/08/16
PIPR
06/08/16
NO CHANGE
PIPR
Osiris rating suspended at Piper Jaffray
Piper Jaffray analyst Edward Tenthoff suspended his rating on Osiris Therapeutics pending "greater clarity" into the company's outstanding accounting issues and Justice Department/SEC investigations. Tenthoff had an Overweight rating on the shares with a $12 price target.
08/04/16
08/04/16
NO CHANGE

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