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JUNO

Juno Therapeutics

$29.88

-1.56 (-4.96%)

08:02
11/23/16
11/23
08:02
11/23/16
08:02

Juno places Phase II ROCKET trial on hold after patient death

Juno Therapeutics announced that it has voluntarily placed on hold the Phase II clinical trial of JCAR015 in adult patients with relapsed or refractory B cell acute lymphoblastic leukemia, known as the "ROCKET" trial. The clinical hold was initiated after two patients suffered cerebral edema earlier this week. One patient died and as of last night the other is not expected to recover. Juno said it has notified the Food & Drug Administration of the voluntary hold and is working with the agency and the Data and Safety Monitoring Board to determine next steps. The company is assessing data from the cases and the trial and is evaluating its options regarding the JCAR015 program. Juno's trials and plans for its other CD19-directed CAR T cell product candidates, including JCAR017, are not affected.

  • 03

    Dec

  • 03

    Dec

JUNO Juno Therapeutics
$29.88

-1.56 (-4.96%)

09/27/16
LEER
09/27/16
NO CHANGE
LEER
Outperform
Kite's ZUMA-1 interim data incrementally positive for Juno, says Leerink
Leerink analyst Michael Schmidt says Kite Pharma's (KITE) top-line interim results from its pivotal ZUMA-1 trial of anti-CD19 CAR-T product KTE-C19 in patients with chemorefractory diffuse large B-cell lymphoma, or DLBCL, are incrementally positive for Juno Therapeutics (JUNO). While Juno is roughly one year behind Kite in DLBCL, the analyst believes its JCAR017 holds the promise to have a compelling safety/efficacy profile in lymphoma and Acute Lymphoblastic Leukemia. He reiterates an Outperform rating on Juno's shares.
11/03/16
BTIG
11/03/16
UPGRADE
BTIG
Neutral
Juno Therapeutics upgraded to Neutral from Sell at BTIG
11/04/16
BTIG
11/04/16
UPGRADE
BTIG
Neutral
Juno Therapeutics upgraded to Neutral from Sell at BTIG
BTIG analyst Dane Leone upgraded Juno Therapeutics (JUNO) to Neutral from Sell citing valuation following the ASH abstract release showed similar response rates for JCAR017 versus Kite's (KITE) KTE-C19 in the treatment of patients with Diffuse Large B-Cell Lymphoma.
11/10/16
RHCO
11/10/16
NO CHANGE
RHCO
Juno Therapeutics drug could deliver best in class data, says SunTrust
SunTrust analyst Peter Lawson says that Juno's non-Hodgkin lymphoma,treatment, JCAR017, could deliver best in class data at ASH. The analyst reiterates a $48 price target and a Buy rating on the shares.

TODAY'S FREE FLY STORIES

HSIC

Henry Schein

$173.53

1.61 (0.94%)

18:45
02/24/17
02/24
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18:45
Conference/Events
Henry Schein management to meet with Jefferies »

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    Feb

TWX

Time Warner

$97.28

0.6225 (0.64%)

18:38
02/24/17
02/24
18:38
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Periodicals
Turner, Univision to win U.S. Champions League rights, Bloomberg reports »

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    Mar

TRUE

TrueCar

$14.28

0.18 (1.28%)

18:33
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02/24
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18:33
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TrueCar's ALG sees February total new vehicle sales 1.325M units, down 1.4% »

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  • 27

    Feb

GE

General Electric

$30.19

0.17 (0.57%)

18:24
02/24/17
02/24
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18:24
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GE does not see after-tax charges from GE Capital exit plan to exceed $23B »

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CE

Celanese

$88.79

-0.88 (-0.98%)

18:02
02/24/17
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18:02
Hot Stocks
Celanese announces vinyl acetate-based emulsions price increases in Asia »

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ELNK

EarthLink

$5.63

-0.22 (-3.76%)

, WIN

Windstream

$7.27

-0.02 (-0.27%)

17:56
02/24/17
02/24
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17:56
Hot Stocks
EarthLink, Windstream holders approve merger »

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ELNK

EarthLink

$5.63

-0.22 (-3.76%)

WIN

Windstream

$7.27

-0.02 (-0.27%)

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PFE

Pfizer

$34.26

0.2 (0.59%)

17:43
02/24/17
02/24
17:43
02/24/17
17:43
Periodicals
Pfizer subpoenaed in investigation of charity connections, Bloomberg says »

Pfizer has received two…

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C

Citi

$59.56

-1.06 (-1.75%)

17:32
02/24/17
02/24
17:32
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17:32
Hot Stocks
U.S. regulators investigating Citi over foreign hiring practices »

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FDX

FedEx

$193.11

1.93 (1.01%)

17:25
02/24/17
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Hot Stocks
FedEx, USPS amend transportation agreement »

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URRE

Uranium Resources

$1.94

-0.09 (-4.43%)

17:21
02/24/17
02/24
17:21
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17:21
Syndicate
Breaking Syndicate news story on Uranium Resources »

Uranium Resources files…

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RTN

Raytheon

$153.48

0.19 (0.12%)

17:13
02/24/17
02/24
17:13
02/24/17
17:13
Hot Stocks
Raytheon awarded $1B government contract »

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COTV

Cotiviti Holdings

$38.74

-0.06 (-0.15%)

17:06
02/24/17
02/24
17:06
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17:06
Syndicate
Breaking Syndicate news story on Cotiviti Holdings »

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  • 22

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ENH

Endurance Specialty

$92.90

0.02 (0.02%)

17:05
02/24/17
02/24
17:05
02/24/17
17:05
Earnings
Endurance reports Q4 EPS 30c, may not compare to consensus $1.26 »

Reports Q4 gross premiums…

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ORPN

Bio Blast Pharma

$1.13

-0.0098 (-0.86%)

17:04
02/24/17
02/24
17:04
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17:04
Syndicate
Breaking Syndicate news story on Bio Blast Pharma »

Bio Blast Pharma files to…

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MNTA

Momenta

$15.40

0.3 (1.99%)

, PFE

Pfizer

$34.26

0.2 (0.59%)

16:44
02/24/17
02/24
16:44
02/24/17
16:44
General news
On The Fly: Stocks end week higher as rally continues »

Stocks ended the week…

MNTA

Momenta

$15.40

0.3 (1.99%)

PFE

Pfizer

$34.26

0.2 (0.59%)

STLD

Steel Dynamics

$35.59

0.07 (0.20%)

AKS

AK Steel

$8.02

-0.1 (-1.23%)

X

U.S. Steel

$37.01

-0.3 (-0.80%)

FLR

Fluor

$55.09

-0.26 (-0.47%)

GVA

Granite Construction

$53.91

0.78 (1.47%)

VMC

Vulcan Materials

$117.82

1.47 (1.26%)

PWR

Quanta Services

$37.76

0.62 (1.67%)

ACM

AECOM

$35.77

-0.58 (-1.60%)

JEC

Jacobs Engineering

$56.03

-0.07 (-0.12%)

KBR

KBR

$15.60

-0.55 (-3.41%)

CBI

CB&I

$33.87

-0.02 (-0.06%)

MTZ

MasTec

$40.10

3.05 (8.23%)

KHC

Kraft Heinz

$93.08

0.14 (0.15%)

UN

Unilever; also tag UL

$46.91

0.33 (0.71%)

UL

Unilever; also tag UN

$47.12

0.22 (0.47%)

QSR

Restaurant Brands

$55.47

-0.08 (-0.14%)

PLKI

Popeyes

TROX

Tronox

$17.40

-0.67 (-3.71%)

WMT

Wal-Mart

$72.39

1.08 (1.51%)

HD

Home Depot

$145.95

1.24 (0.86%)

CYH

Community Health

$9.22

0.32 (3.60%)

TOL

Toll Brothers

$33.74

-0.22 (-0.65%)

GRMN

Garmin

$53.03

0.72 (1.38%)

CHS

Chico's

$14.75

0.3 (2.08%)

HPQ

HP Inc.

$17.65

0.05 (0.28%)

CRI

Carter's

$90.04

2.98 (3.42%)

SQ

Square

$17.43

0.28 (1.63%)

JWN

Nordstrom

$46.46

2.52 (5.74%)

FL

Foot Locker

$75.01

6.43 (9.38%)

AAOI

Applied Optoelectronics

$45.98

8.51 (22.71%)

RH

Restoration Hardware

$31.34

6.15 (24.41%)

M

Macy's

$33.17

0.73 (2.25%)

PZZA

Papa John's

$78.70

-0.07 (-0.09%)

FSLR

First Solar

$37.90

0.71 (1.91%)

TXRH

Texas Roadhouse

$42.22

0.13 (0.31%)

TSLA

Tesla

$257.00

1.01 (0.39%)

LB

Labarge

$50.99

2.05 (4.19%)

W

Wayfair

$39.30

0.72 (1.87%)

HPE

HP Enterprise

$22.96

-1.7 (-6.89%)

JCP

J.C. Penney

$6.46

-0.4 (-5.83%)

ACIA

Acacia Communications

$54.04

-9.39 (-14.80%)

BGS

B&G Foods

$43.65

-3.25 (-6.93%)

SPLK

Splunk

$62.80

-2.1 (-3.24%)

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  • 17

    Apr

NBEV

New Age Beverages

$3.90

-0.04 (-1.02%)

16:41
02/24/17
02/24
16:41
02/24/17
16:41
Hot Stocks
Breaking Hot Stocks news story on New Age Beverages »

Park West AM reports 6.3%…

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CYTX

Cytori Therapeutics

$1.71

-0.07 (-3.93%)

16:40
02/24/17
02/24
16:40
02/24/17
16:40
Hot Stocks
Breaking Hot Stocks news story on Cytori Therapeutics »

Azaya Therapeutics…

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ADMA

ADMA Biologics

$4.75

-0.03 (-0.63%)

16:40
02/24/17
02/24
16:40
02/24/17
16:40
Earnings
ADMA Biologics reports FY16 EPS ($1.61), consensus ($1.57) »

Reports FY16 revenue…

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WFC

Wells Fargo

$57.81

-0.68 (-1.16%)

16:38
02/24/17
02/24
16:38
02/24/17
16:38
Syndicate
Breaking Syndicate news story on Wells Fargo »

Wells Fargo files…

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  • 13

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  • 15

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SHO

Sunstone Hotel

$14.71

-0.05 (-0.34%)

16:36
02/24/17
02/24
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02/24/17
16:36
Syndicate
Breaking Syndicate news story on Sunstone Hotel »

Sunstone Hotel files…

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TPHS

Trinity Place

$9.97

0.47 (4.95%)

16:36
02/24/17
02/24
16:36
02/24/17
16:36
Hot Stocks
Breaking Hot Stocks news story on Trinity Place »

Horse Island Partners…

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SO

Southern Company

$50.50

0.83 (1.67%)

16:35
02/24/17
02/24
16:35
02/24/17
16:35
Syndicate
Breaking Syndicate news story on Southern Company »

Southern Company's…

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  • 28

    Feb

MENT

Mentor Graphics

, SIEGY

Siemens

$128.94

-1.35 (-1.04%)

16:35
02/24/17
02/24
16:35
02/24/17
16:35
Hot Stocks
KFTC clears pending merger of Mentor Graphics and Siemens »

According to a regulatory…

MENT

Mentor Graphics

SIEGY

Siemens

$128.94

-1.35 (-1.04%)

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  • 27

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    Feb

HPE

HP Enterprise

$22.96

-1.7 (-6.89%)

, JCP

J.C. Penney

$6.46

-0.4 (-5.83%)

16:32
02/24/17
02/24
16:32
02/24/17
16:32
General news
On The Fly: Top stock stories for Friday »

Stocks opened with modest…

HPE

HP Enterprise

$22.96

-1.7 (-6.89%)

JCP

J.C. Penney

$6.46

-0.4 (-5.83%)

JWN

Nordstrom

$46.46

2.52 (5.74%)

FL

Foot Locker

$75.01

6.43 (9.38%)

RH

Restoration Hardware

$31.34

6.15 (24.41%)

ACIA

Acacia Communications

$54.04

-9.39 (-14.80%)

BGS

B&G Foods

$43.65

-3.25 (-6.93%)

03/08/13
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16:31
02/24/17
02/24
16:31
02/24/17
16:31
Options
Preliminary option volume of 16.9M today »

Preliminary option volume…

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