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OPXA

Opexa Therapeutics

$0.91

-0.143 (-13.62%)

07:36
11/25/16
11/25
07:36
11/25/16
07:36

Opexa reports Merck Serono not exercising option to buy Tcelna license

In a regulatory filing, Opexa Therapeutics (OPXA) reported that it received notice from Ares Trading, a wholly owned subsidiary of Merck Serono, that Merck Serono would not be exercising its option to acquire the exclusive, worldwide ex. Japan license to the company's Tcelna program for the treatment of multiple sclerosis granted to Merck Serono under the Option and License Agreement dated February 4, 2013, as amended. As a result of receiving the notice from Merck Serono, the agreement automatically expired upon receipt. As previously announced on October 28, 2016, the company's Phase IIb Abili-T clinical trial designed to evaluate the efficacy and safety of Tcelna in patients with secondary progressive MS did not meet its primary or secondary endpoints.

OPXA Opexa Therapeutics
$0.91

-0.143 (-13.62%)

11/25/15
MAXM
11/25/15
NO CHANGE
MAXM
Opexa Therapeutics mentioned positively at Maxim
06/10/16
MAXM
06/10/16
NO CHANGE
MAXM
Buy
Maxim sees potential for Opexa's Tcelna as adjuvant to stem cell transplant
Maxim analyst Jason McCarthy noted that a study published this morning in The Lancet recounts a phase 2 trial of immunoablation and autologous haemopoietic stem-cell transplantation for aggressive multiple sclerosis wherein 70% of patients achieved the primary endpoint of MS activity-free survival at three years post transplant. McCarthy noted that he we now sees the potential for Opexa Therapeutics' Tcelna as an adjuvant to stem cell transplant to extend already long disease-free responses, adding "if we see it, we believe Opexa and big pharma could see the potential too." The firm has a Buy rating on Opexa shares, which are up 15% near midday.
10/28/16
AGIS
10/28/16
DOWNGRADE
AGIS
Hold
Opexa Therapeutics downgraded to Hold from Buy at Aegis
Aegis downgraded Opexa Therapeutics to Hold after Tcelna trial failure.
10/31/16
MAXM
10/31/16
DOWNGRADE
MAXM
Hold
Opexa Therapeutics downgraded to Hold from Buy at Maxim
Maxim analyst Jason McCarthy downgraded Opexa Therapeutics to Hold from Buy on October 28, citing the failure of Tcelna, the company's T cell-based immunotherapy for the treatment of Secondary Progressive Multiple Sclerosis, in a phase 2b study. The analyst said he thinks it is unlikely that Tcelna can move forward in MS, though noted that there are other programs, such as NMO, that Opexa has that may be able to move forward.

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