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NVLS

Nivalis Therapeutics

$6.25

-0.03 (-0.48%)

16:12
11/28/16
11/28
16:12
11/28/16
16:12

Nivalis Phase 2 trial does not meet primary endpoint

Nivalis Therapeutics announced topline results from the company's Phase 2 trial evaluating the efficacy and safety of two doses of cavosonstat, 200 mg and 400 mg, in adult patients with cystic fibrosis, or CF, who had two copies of the F508del-CFTR mutation and were being treated with Orkambi. There were no dose limiting toxicities and cavosonstat was well tolerated at all doses in the trial. The trial failed, however, to demonstrate benefit in absolute change in percent predicted FEV1, the trial's primary endpoint, or in sweat chloride reduction at 12 weeks.

NVLS Nivalis Therapeutics
$6.25

-0.03 (-0.48%)

09/13/16
RAJA
09/13/16
INITIATION
Target $20
RAJA
Outperform
Nivalis Therapeutics initiated with an Outperform at Raymond James
Raymond James analyst Christopher Raymond initiated Nivalis Therapeutics with an Outperform and a $20 price target. Raymond believes Nivalis' lead asset cavosonstat could provide one of the earliest triple-combo readouts in the cystic fibrosis space and views risk/reward as favorable ahead of the readout.

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EVHC

Envision Healthcare

$69.19

-2.51 (-3.50%)

06:55
12/08/16
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Initiation
Envision Healthcare initiated  »

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06:55
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General news
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MEI

Methode Electronics

$39.00

0.45 (1.17%)

06:54
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Methode Electronics raises FY17 EPS view to $2.30-$2.45 from $2.11-$2.35 »

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  • 08

    Dec

IGT

International Game

$25.49

0.36 (1.43%)

, SNE

Sony

$28.61

0.45 (1.60%)

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$25.49

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SNE

Sony

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MEI

Methode Electronics

$39.00

0.45 (1.17%)

06:53
12/08/16
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Earnings
Methode Electronics reports Q2 EPS 66c, consensus 55c »

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  • 08

    Dec

VRNT

Verint

$38.30

0.1 (0.26%)

06:52
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  • 08

    Dec

AMC

AMC Entertainment

$32.65

-1.15 (-3.40%)

, CKEC

Carmike Cinemas

$33.45

-0.4 (-1.18%)

06:49
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AMC Entertainment and Carmike Cinemas announce election deadline »

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AMC Entertainment

$32.65

-1.15 (-3.40%)

CKEC

Carmike Cinemas

$33.45

-0.4 (-1.18%)

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SCBFF

Standard Chartered

$8.68

0.28 (3.33%)

06:47
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StanChart sanctions investigation nearing completion, Bloomberg reports »

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HP

Helmerich & Payne

$80.86

0.94 (1.18%)

06:46
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Helmerich & Payne rating change  »

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LULU

lululemon

$59.84

2.6 (4.54%)

06:45
12/08/16
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Upgrade
lululemon rating change  »

lululemon upgraded to…

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  • 09

    Jan

PRGO

Perrigo

$83.94

-0.53 (-0.63%)

06:44
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Perrigo announces portfolio review developments, intends to restructure BCH unit »

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CEB

CEB

$59.50

0.35 (0.59%)

06:43
12/08/16
12/08
06:43
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06:43
Downgrade
CEB rating change  »

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UHS

Universal Health

$111.36

-15.01 (-11.88%)

06:42
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Universal Health issues statement on recent BuzzFeed article »

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  • 08

    Dec

GOOGL

Alphabet Class A

$791.47

15.29 (1.97%)

, GOOG

Alphabet

$771.19

12.08 (1.59%)

06:42
12/08/16
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06:42
Recommendations
Alphabet Class A, Alphabet, Facebook, Amazon.com analyst commentary  »

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GOOGL

Alphabet Class A

$791.47

15.29 (1.97%)

GOOG

Alphabet

$771.19

12.08 (1.59%)

FB

Facebook

$117.95

0.64 (0.55%)

AMZN

Amazon.com

$770.42

5.7 (0.75%)

03/08/13
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  • 15

    Jan

SMG

Scotts Miracle-Gro

$92.84

2.01 (2.21%)

06:41
12/08/16
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06:41
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Scotts Miracle-Gro rating change  »

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ARAY

Accuray

06:40
12/08/16
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Accuray reports first patients treated with new Radixact system »

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  • 08

    Dec

TAX

Liberty Tax

$13.35

0.5 (3.89%)

06:38
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Earnings
Liberty Tax reports Q2 EPS (72c), consensus (71c) »

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  • 08

    Dec

ZEN

Zendesk

$21.15

-0.02 (-0.09%)

06:38
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Conference/Events
Zendesk management to meet with William Blair »

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  • 08

    Dec

AMZN

Amazon.com

$770.42

5.7 (0.75%)

06:38
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Periodicals
Amazon seeks to help publishers profit more from ads, WSJ says »

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INFN

Infinera

$8.48

0.01 (0.12%)

06:37
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Conference/Events
Infinera management to meet with William Blair »

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  • 08

    Dec

LLL

L-3 Communications

$161.56

3.1 (1.96%)

06:36
12/08/16
12/08
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Downgrade
L-3 Communications rating change  »

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BLL

Ball Corp.

$75.58

1.38 (1.86%)

06:34
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Recommendations
Ball Corp. analyst commentary  »

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  • 13

    Dec

YGE

Yingli Green Energy

$3.23

0.12 (3.86%)

06:34
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Yingli Green Energy sees Q4 PV module shipments 600MW-670MW »

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  • 08

    Dec

MPLX

MPLX

$31.69

-0.01 (-0.03%)

06:34
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MPLX rating change  »

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YGE

Yingli Green Energy

$3.23

0.12 (3.86%)

06:34
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Earnings
Yingli Green Energy reports Q3 EPS (28c), may not compare to consensus ($1.39) »

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  • 08

    Dec

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