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DMTX

Dimension Therapeutics

$4.20

-0.3 (-6.67%)

08:08
11/29/16
11/29
08:08
11/29/16
08:08

Dimension Therapeutics receives positive opinion for EU ODD of DTX401

Dimension Therapeutics announced that the European Medicines Agency, or EMA, Committee for Orphan Medicinal Products has issued a positive opinion recommending DTX401 for designation as an orphan medicinal product for the treatment of Glycogen Storage Disease Type Ia, or GSDIa. The positive opinion for DTX401 is a key milestone for Dimension's leading and unique program advancing the opportunity for AAV gene therapy for patients with limited treatment options to manage their disease. Designed to address the underlying genetic defect, DTX401 has been shown in multiple in vivo preclinical models to deliver stable expression and activity of the enzyme glucose-6-phosphatase-alpha. DTX401 has also been shown to improve G6Pase-alpha activity and reduce hepatic glycogen levels, a well-described biomarker of disease progression. Dimension has completed candidate selection for its DTX401 program and is currently in IND-enabling studies.

  • 03

    Dec

DMTX Dimension Therapeutics
$4.20

-0.3 (-6.67%)

02/18/16
CANT
02/18/16
INITIATION
Target $10
CANT
Buy
Dimension Therapeutics initiated with a Buy at Cantor
Cantor Fitzgerald analyst Caroline Corner started Dimension Therapeutics with a Buy rating and $10 price target.
03/30/16
GSCO
03/30/16
DOWNGRADE
Target $10
GSCO
Neutral
Dimension Therapeutics downgraded to Neutral from Buy at Goldman
Goldman Sachs analyst Salveen Richter downgraded Dimension Therapeutics (DMTX) to Neutral saying other names in the sector offer better near-term opportunities. The analyst views Dimension as well-positioned in the gene therapy space, however. He lowered his price target for the shares to $10 from $12. Richter this morning also initiated SAGE Therapeutics (SAGE) with a Buy rating and Acorda Therapeutics (ACOR) with a Sell rating.
06/02/16
JEFF
06/02/16
INITIATION
Target $12
JEFF
Buy
Dimension Therapeutics initiated with a Buy at Jefferies
Jefferies analyst Gena Wang started Dimension Therapeutics with a Buy rating and $12 price target.
06/02/16
CANT
06/02/16
NO CHANGE
Target $32
CANT
Buy
Dimension Therapeutics coverage assumed with a Buy at Cantor
Target $32.

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NXTM

NxStage Medical

$23.46

0.13 (0.56%)

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BL

BlackLine

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-0.26 (-0.68%)

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ULTI

Ultimate Software

$221.91

-0.25 (-0.11%)

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CRM

Salesforce

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EVBG

Everbridge

$24.66

-0.3 (-1.20%)

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RNG

RingCentral

$37.65

-1 (-2.59%)

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WK

Workiva

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HUBS

HubSpot

$68.20

-0.7 (-1.02%)

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HUBS

HubSpot

$68.20

-0.7 (-1.02%)

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QTWO

Q2 Holdings

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Initiation
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INST

Instructure

$29.55

0.4 (1.37%)

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MANH

Manhattan Associates

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PCTY

Paylocity

$47.39

-1.65 (-3.36%)

20:55
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Initiation
Paylocity initiated at SunTrust »

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SHOP

Shopify

$92.04

-2.44 (-2.58%)

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LH

LabCorp

$152.30

0.68 (0.45%)

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LabCorp rating change at KeyBanc »

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ATXI

Avenue Therapeutics

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NXPI

NXP Semiconductors

$109.73

-0.25 (-0.23%)

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PDCE

PDC Energy

$42.88

-1.84 (-4.11%)

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MRIN

Marin Software

$1.18

0.025 (2.17%)

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GM

General Motors

$34.52

0.32 (0.94%)

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Earnings
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