Breaking News Instant updates and real-time market news.

NVO

Novo Nordisk

$32.66

0.12 (0.37%)

13:04
11/29/16
11/29
13:04
11/29/16
13:04

Novo Nordisk says achieved primary endpoint in DEVOTE trial

Novo Nordisk announced the headline results from the DEVOTE trial, a long-term, randomized, double-blinded and event-driven trial conducted to confirm the cardiovascular safety of Tresiba compared to insulin glargine U100 when added to standard of care. In the trial, more than 7,500 people with type 2 diabetes at high risk of major adverse cardiovascular events were treated for a period of approximately two years.The trial achieved its primary endpoint by demonstrating non-inferiority of major adverse cardiovascular events with Tresiba compared to insulin glargine U100. The trial thereby confirmed the results of the DEVOTE interim analysis submitted to the U.S. FDA in March 2015, on the basis of which Tresiba and Ryzodeg 70/30 were approved in the U.S. in September 2015. The primary endpoint of the DEVOTE study was defined as the MACE composite outcome of the first occurrence of cardiovascular death, non-fatal myocardial infarction or non-fatal stroke and showed a hazard ratio of 0.91 in favour of Tresiba relative to insulin glargine U100, with no statistically significant difference between the two treatments. In the trial, Tresiba demonstrated superiority on the secondary confirmatory endpoint of severe hypoglycaemia: 27% fewer patients in the Tresiba treated group experienced an episode of severe hypoglycaemia, resulting in a 40% overall reduction of total episodes of adjudicated severe hypoglycaemia. Furthermore, patients in the Tresiba treated group experienced a 54% relative reduction in the rate of nocturnal severe hypoglycaemia. These differences were all statistically significant. Tresiba appeared to have a safe and well-tolerated profile consistent with previous clinical studies conducted with Tresiba.Novo Nordisk expects to present the detailed results of the DEVOTE trial at a scientific meeting and submit the findings for review with regulatory authorities during the first half of 2017.

  • 29

    Nov

  • 07

    Dec

NVO Novo Nordisk
$32.66

0.12 (0.37%)

09/13/16
EXAN
09/13/16
UPGRADE
EXAN
Outperform
Novo Nordisk upgraded to Outperform from Neutral at Exane BNP Paribas
09/23/16
PIPR
09/23/16
INITIATION
PIPR
Neutral
Novo Nordisk initiated with a Neutral at Piper Jaffray
Piper Jaffray analyst Richard Purkiss started Novo Nordisk with a Neutral rating and DKK 320 price target.
10/28/16
BOFA
10/28/16
DOWNGRADE
BOFA
Underperform
Novo Nordisk downgraded to Underperform from Neutral at BofA/Merrill
10/31/16
SBSH
10/31/16
DOWNGRADE
SBSH
Neutral
Novo Nordisk downgraded to Neutral from Buy at Citi
Citi analyst Peter Verdult downgraded Novo Nordisk to Neutral citing the ongoing net pricing declines across the company's diabetes portfolio as well as expectations for margin erosion at Biopharmaceuticals due to NovoSeven/Norditropin pressures. The analyst cut his price target for the shares to DKK 260 from DKK 400.

TODAY'S FREE FLY STORIES

LGF

Use LGF.A, LGF.B

09:39
06/23/17
06/23
09:39
06/23/17
09:39
Conference/Events
Use LGF.A, LGF.B management to meet with B. Riley »

Meeting to be held in New…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Jun

INN

Summit Hotel Properties

09:38
06/23/17
06/23
09:38
06/23/17
09:38
Conference/Events
Summit Hotel Properties management to meet with Canaccord »

Meeting to be held in…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Jun

  • 13

    Jul

IMGN

ImmunoGen

$5.82

-0.2 (-3.32%)

09:38
06/23/17
06/23
09:38
06/23/17
09:38
Conference/Events
ImmunoGen management to meet with Jefferies »

Meetings to be held in…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Jun

  • 28

    Jun

REGN

Regeneron

$526.53

4.51 (0.86%)

09:36
06/23/17
06/23
09:36
06/23/17
09:36
Hot Stocks
Breaking Hot Stocks news story on Regeneron »

Regeneron down 4.6% to…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

ETSY

Etsy

$14.68

0.48 (3.38%)

09:36
06/23/17
06/23
09:36
06/23/17
09:36
Periodicals
Several private equity firms have reached out to Etsy, Dealreporter says »

While Etsy has not been…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

CAT

Caterpillar

09:36
06/23/17
06/23
09:36
06/23/17
09:36
Technical Analysis
Technical View: Caterpillar slips lower, analyst action »

Shares were last down…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

HQY

HealthEquity

$51.05

-0.39 (-0.76%)

09:36
06/23/17
06/23
09:36
06/23/17
09:36
Conference/Events
HealthEquity management to meet with Barrington »

Meeting to be held in…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 27

    Jun

APLP

Archrock Partners LP

$13.66

0.61 (4.67%)

09:35
06/23/17
06/23
09:35
06/23/17
09:35
Downgrade
Archrock Partners LP rating change  »

Archrock Partners LP…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

09:35
06/23/17
06/23
09:35
06/23/17
09:35
General news
U.S. new home sales preview: »

U.S. new home sales…

AROC

Archrock

09:34
06/23/17
06/23
09:34
06/23/17
09:34
Downgrade
Archrock rating change  »

Archrock downgraded to…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

WRE

Washington REIT

09:32
06/23/17
06/23
09:32
06/23/17
09:32
Conference/Events
Washington REIT management to meet with JPMorgan »

Meeting to be held in…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 29

    Jun

  • 28

    Jul

  • 27

    Oct

09:30
06/23/17
06/23
09:30
06/23/17
09:30
General news
PMI Composite Flash â€' Level to be reported at 09:45 »

June PMI Composite Flash…

09:30
06/23/17
06/23
09:30
06/23/17
09:30
General news
PMI Composite Flash Manufacturing â€' Level to be reported at 09:45 »

June PMI Composite Flash…

ADHD

Alcobra

, AVEO

AVEO Oncology

$0.73

0.0281 (4.02%)

09:29
06/23/17
06/23
09:29
06/23/17
09:29
Hot Stocks
On The Fly: Pre-market Movers »

HIGHER: Alcobra (ADHD),…

ADHD

Alcobra

AVEO

AVEO Oncology

$0.73

0.0281 (4.02%)

SNCR

Synchronoss

$12.18

1.53 (14.37%)

BBRY

BlackBerry

$11.06

0.41 (3.85%)

BBBY

Bed Bath & Beyond

$33.74

0.08 (0.24%)

BLCM

Bellicum Pharmaceuticals

$13.98

1.33 (10.51%)

BLUE

bluebird bio

$118.50

-1.8 (-1.50%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 23

    Jun

  • 23

    Jun

  • 23

    Jun

  • 29

    Jun

  • 26

    Sep

RIO

Rio Tinto

, GLNCY

Glencore

$7.10

0.05 (0.71%)

09:29
06/23/17
06/23
09:29
06/23/17
09:29
Hot Stocks
Glencore raises offer for Rio Tinto's Coal & Allied to $2.675B plus royalties »

Glencore (GLNCY)…

RIO

Rio Tinto

GLNCY

Glencore

$7.10

0.05 (0.71%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

ALGN

Align Technology

$149.69

0.27 (0.18%)

09:28
06/23/17
06/23
09:28
06/23/17
09:28
Conference/Events
Stifel medical technology analysts hold an analyst/industry conference call »

Research Team discusses…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 23

    Jun

  • 26

    Jun

PAAS

Pan American Silver

$16.95

0.51 (3.10%)

09:28
06/23/17
06/23
09:28
06/23/17
09:28
Conference/Events
Pan American Silver management to meet with JPMorgan »

Meeting to be held in San…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 29

    Jun

BAESY

BAE Systems

$34.19

-0.635 (-1.82%)

09:25
06/23/17
06/23
09:25
06/23/17
09:25
Downgrade
BAE Systems rating change  »

BAE Systems downgraded to…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

09:25
06/23/17
06/23
09:25
06/23/17
09:25
General news
Fed funds futures are unchanged to modestly lower »

Fed funds futures are…

CRNCY

Cairn Energy

$4.44

0.15 (3.50%)

09:24
06/23/17
06/23
09:24
06/23/17
09:24
Conference/Events
Cairn Energy management to meet with JPMorgan »

Meetings to be held in…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 29

    Jun

RHHBY

Roche

$32.30

-0.3 (-0.92%)

09:22
06/23/17
06/23
09:22
06/23/17
09:22
Hot Stocks
Roche receives FDA approval for Elecsys HIV combi PT assay »

Roche announced that its…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 26

    Jun

  • 13

    Jul

P

Pandora

, SIRI

SiriusXM

09:22
06/23/17
06/23
09:22
06/23/17
09:22
Recommendations
Pandora, SiriusXM analyst commentary  »

Pandora selloff since…

P

Pandora

SIRI

SiriusXM

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 28

    Jun

ASML

ASML

$130.02

-0.41 (-0.31%)

09:20
06/23/17
06/23
09:20
06/23/17
09:20
Recommendations
ASML analyst commentary  »

ASML shares could double…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 29

    Aug

RGA

Reinsurance Group

09:20
06/23/17
06/23
09:20
06/23/17
09:20
Conference/Events
Reinsurance Group management to meet with JPMorgan »

Meetings to be held in…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 28

    Jun

  • 29

    Jun

HUM

Humana

, COF

Capital One

09:19
06/23/17
06/23
09:19
06/23/17
09:19
Hot Stocks
Humana appoints Sam Deshpande as CRO »

Humana (HUM) has named…

HUM

Humana

COF

Capital One

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 20

    Jul

Get Full Fly Access

Breaking market intelligence sent straight to you
Our team of experts analyze every news story and filter out the noise to deliver real-time market moving news.
Up-to-date information on important industry events
Get real-time updates on events that are moving the market—from conferences and calls to syndicate announcements.
News focused on the companies in your portfolio
Create up to 12 portfolios with 150 stocks each, and see how active they are in market news.