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CLVS

Clovis

$34.39

-2.99 (-8.00%)

13:19
11/29/16
11/29
13:19
11/29/16
13:19

Results of part 1 of Clovis ARIEL2 study published in The Lancet Oncology

The results of part 1 of the ARIEL2 study, an international, multicentre, two-part, phase 2, open-label study, were published in The Lancet Oncology. Enrolment into ARIEL2 Part 1 is complete, although an extension, Part 2, is ongoing. "In patients with BRCA mutant or BRCA wild-type and LOH high platinum-sensitive ovarian carcinomas treated with rucaparib, progression-free survival was longer than in patients with BRCA wild-type LOH low carcinomas. Our results suggest that assessment of tumour LOH can be used to identify patients with BRCA wild-type platinum-sensitive ovarian cancers who might benefit from" Clovis' rucaparib, the interpretation statement of the text states in the version published online. Reference Link

  • 29

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    Feb

CLVS Clovis
$34.39

-2.99 (-8.00%)

10/07/16
RHCO
10/07/16
NO CHANGE
Target $50
RHCO
Buy
Clovis selloff a buying opportunity, says SunTrust
SunTrust analyst Peter Lawson views today's selloff in shares of Clovis Oncology as a buying opportunity, saying today's concern "seems like noise." The analyst has a Buy rating on the stock with a $50 price target. Clovis is down 13%, or $4.64, to $31.13 but is well off the day's lows.
10/25/16
CHDN
10/25/16
INITIATION
Target $15
CHDN
Sell
Clovis initiated with a Sell at Chardan
Chardan analyst Madhu Kumar initiated Clovis with a Sell and a $15 price target.
10/25/16
CHDN
10/25/16
INITIATION
CHDN
Sell
Clovis initiated with a Sell on rucaparib worries at Chardan
As noted earlier, Chardan analyst Madhu Kumar initiated coverage of Clovis with a Sell rating and a $15 price target. Kumar says that "the lack of efficacy" and "safety signals" of the company's rucaparib drug pose "considerable risks" ahead of its February 23, 2017 PDUFA date. The analyst says that the drug "does not appear" to have greater efficacy than existing treatments, as any advantages it shows over the standard of care are not statistically significant. He adds that the product has caused many more adverse events than approved drugs that treat ovarian cancer.
10/26/16
PIPR
10/26/16
NO CHANGE
PIPR
Neutral
Piper still uncertain on Clovis position after AstraZeneca data
AstraZeneca's (AZN) Phase III study of Lynparza in ovarian cancer "substantially improved" progression-free survival over what was seen in study 19, suggesting a profile at least similar to TESARO's (TSRO) niraparib, Piper Jaffray analyst Steven Breazzano tells investors in a research note. The new data confirm that the various PARP inhibitors are more similar than different, which bodes well for Clovis Oncology's (CLVS) own maintenance study, the analyst contends. Breazzano, however, remains the sidelines with respect to Clovis shares given the "increasingly competitive dynamic" in ovarian cancer and uncertainty in the company's position in the important maintenance setting. The analyst keeps a Neutral rating on Clovis.

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