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RARE

Ultragenyx

$84.19

2.52 (3.09%)

08:33
11/30/16
11/30
08:33
11/30/16
08:33

Ultragenyx announces 'positive' data from UX007 Phase 2 study

Ultragenyx Pharmaceutical announced positive 78-week data from the Phase 2 study of UX007 in patients with long-chain fatty acid oxidation disorder, or LC-FAOD. The frequency and duration of major medical events were reduced significantly during treatment with UX007, and patients demonstrated improved exercise tolerance and quality of life during the study. "The reduction in frequency and duration of hospitalizations and other major medical events suggests a clinically meaningful improvement for patients and is consistent with the data from the prior retrospective compassionate use study," said Emil D. Kakkis, M.D., Ph.D., Chief Executive Officer and President of Ultragenyx. "These results are encouraging and we continue to further develop the Phase 3 study design and endpoints before meeting with regulators and initiating the study in 2017."

RARE Ultragenyx
$84.19

2.52 (3.09%)

10/18/16
JEFF
10/18/16
NO CHANGE
JEFF
Jefferies sees 'attractive buying opportunities' in Biotech
The Jefferies Biotechnology team sees "attractive buying opportunities" amidst the pre-election weakness. While volatility will likely continue into the election, valuation multiples are near-historic lows and policy concerns, while valid, are likely overstated, the analysts tell investors in a research note. They recommend using the weakness to buy select names ahead of a potential improvement in sentiment. Jefferies likes Gilead (GILD) and Celgene (CELG) among large-caps, The Medicines Co. (MDCO), Alkermes (ALKS) and Vertex (VRTX) among mid-caps, and Alder Biopharmaceuticals (ALDR), Cempra (CEMP), Ultragenyx (RARE) and Immunomedics (IMMU) among small-caps.
11/01/16
PIPR
11/01/16
NO CHANGE
Target $82
PIPR
Overweight
Ultragenyx risk/reward favorable after pullback, says Piper Jaffray
Piper Jaffray analyst Steven Breazzano says Ultragenyx's risk/reward profile is favorable following the recent pullback in the shares. The analyst recommends buying the stock based on the blockbuster potential of KRN23 in adult and pediatric X-linked hypophosphatemia patients. After taking a closer look at Ultragenyx's UX007 Phase 2 program for both fatty acid oxidation disorders and Glut1 deficiency syndrome, the analyst sees a greater than 50% chance of success in both. He notes the program would represent "meaningful upside" to his model. He reiterates an Overweight rating on Ultragenyx with an $82 price target.
11/08/16
ADAM
11/08/16
NO CHANGE
Target $108
ADAM
Buy
Ultragenyx price target lowered to $108 from $120 at Canaccord
Canaccord analyst Arlinda Lee lowered her price target on Ultragenyx to $108 from $120 due to an expected increase in R&D spending after the company reported pipeline progress on four clinical candidates and said it expects to file for U.S. KRN23 pediatric approval earlier than expected in the second half of 2017. Lee reiterated her Buy rating on Ultragenyx shares as she expects regulatory approvals in 2017, while also citing its attractive pipeline.
11/14/16
SBSH
11/14/16
DOWNGRADE
Target $64
SBSH
Sell
Ultragenyx downgraded to Sell from Neutral at Citi
Citi analyst Yigal Nochomovitz downgraded Ultragenyx to Sell after removing Ace-ER sales from his model "in the absence of stronger data." The analyst lowered his price target for the shares to $64 from $66.

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