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ACAD

ACADIA

$26.99

-0.66 (-2.39%)

09:02
12/01/16
12/01
09:02
12/01/16
09:02

ACADIA initiates Phase II Pimavanserin trial for MDD

ACADIA Pharmaceuticals announced the initiation of CLARITY, a Phase II study to evaluate pimavanserin for adjunctive treatment in patients with major depressive disorder who have an inadequate response to first-line therapies for clinical depression. Pimavanserin is a selective serotonin inverse agonist preferentially targeting 5-HT2A receptors that may play a role in depression. CLARITY is a Phase II, 10-week, randomized, double-blind, placebo-controlled, multi-center study designed to examine the efficacy and safety of adjunctive use of pimavanserin in patients with major depressive disorder who have an inadequate response to standard antidepressant therapy with either a selective serotonin reuptake inhibitor or a serotonin norepinephrine reuptake inhibitor. Approximately 188 patients will be randomized to receive either 34 mg of pimavanserin or placebo, orally, once daily, in addition to their ongoing antidepressant for 10 weeks. The primary endpoint of the study is the change from baseline on the Hamilton Depression Rating Scale total score.

  • 01

    Dec

  • 02

    Dec

ACAD ACADIA
$26.99

-0.66 (-2.39%)

11/08/16
11/08/16
UPGRADE
Target $35

Buy
ACADIA upgraded to Buy, Nuplazid sales ahead of estimates, says BofA/Merrill
As previously reported, BofA/Merrill upgraded ACADIA to Buy from Neutral. Analyst Tazeen Ahmad said ACADIA reported Q3 Nuplazid sales of $5.3M, above his $2M estimate and consensus of $2.7M. Ahmad sees meaningful upside supported by management's comments that the upcoming Alzheimer Psychosis trial may not need to be statistically significant to warrant advancement. The analyst lowered his price target to $35 from $39 to reflect raised opex estimates and a smaller EU market.
11/08/16
11/08/16
UPGRADE

On The Fly: Top five analyst upgrades
Catch up on today's top five analyst upgrades with this list compiled by The Fly: 1. Sysco (SYY) upgraded to Buy from Neutral at BofA/Merrill with analyst Marisa Sullivan citing greater accretion from the Brakes acquisition in fiscal 2017. 2. Windstream (WIN) upgraded to Outperform from Market Perform at Cowen. 3. ACADIA (ACAD) upgraded to Buy from Neutral at BofA/Merrill with analyst Tazeen Ahmad seeing meaningful upside supported by management's comments that the upcoming Alzheimer Psychosis trial may not need to be statistically significant to warrant advancement. 4. Ferrari (RACE) upgraded to Hold from Sell at Evercore ISI with analyst George Galliers citing the LaFerrari Aperta coming to market sooner than expected and incremental contribution and the somewhat defensive nature of the stock. 5. Energy Transfer Equity (ETE) upgraded to Outperform from Market Perform at Bernstein with analyst Jean Ann Salisbury saying Energy Transfer's stock is trading as though the company's Dakota Access and Rover projects will be canceled. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
11/11/16
GSCO
11/11/16
INITIATION
Target $28
GSCO
Neutral
ACADIA initiated with a Neutral at Goldman
Goldman analyst Salveen Richter initiated ACADIA with a Natural and a $28 price target citing an expected gradual launch of its sole drug Nuplazid for Parkinson's disease psychosis due to limited physician disease awareness.
11/11/16
11/11/16
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Aegerion (AEGN) resumed with a Neutral at JPMorgan. 2. Lamb Weston (LW) initiated with a Buy at Stifel, initiated with an Overweight at Barclays, and an Equal Weight at Morgan Stanley. 3. bluebird bio (BLUE) initiated with a Market Perform at BMO Capital. 4. Alder Biopharmaceuticals (ALDR) initiated with an Outperform at BMO Capital. 5. ACADIA (ACAD) initiated with a Neutral at Goldman. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.

TODAY'S FREE FLY STORIES

DDAIF

Daimler AG

$71.14

0.0425 (0.06%)

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LMT

Lockheed Martin

$275.61

2.52 (0.92%)

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TMUS

T-Mobile

$64.70

-0.11 (-0.17%)

15:05
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T Mobile options imply 6.4% move in share price post-earnings, above median historical move »

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AAL

American Airlines

$45.15

-0.07 (-0.15%)

, UAL

United Continental

$70.80

1.24 (1.78%)

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AAL

American Airlines

$45.15

-0.07 (-0.15%)

UAL

United Continental

$70.80

1.24 (1.78%)

03/08/13
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  • 27

    Apr

WFM

Whole Foods

$35.71

0.21 (0.59%)

15:01
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04/24
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Options
Notable implied volatility spike in Whole Foods as shares rally »

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    May

15:00
04/24/17
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General news
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UTX

United Technologies

$116.15

1.155 (1.00%)

14:51
04/24/17
04/24
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14:51
Options
United Tech attracts call buyers as shares rally to new highs »

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ABX

Barrick Gold

$19.21

-0.025 (-0.13%)

14:50
04/24/17
04/24
14:50
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14:50
Options
Barrick Gold options imply 4.9% move in share price post-earnings, above median historical move »

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BCR

C.R. Bard

$303.97

50.9 (20.11%)

14:49
04/24/17
04/24
14:49
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14:49
Downgrade
C.R. Bard rating change  »

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AAPL

Apple

$142.27

-0.17 (-0.12%)

14:48
04/24/17
04/24
14:48
04/24/17
14:48
Periodicals
Apple reduces App Store affiliated commission to 2.5% from 7%, TechCrunch says »

Apple has informed…

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  • 02

    May

NVS

Novartis

$74.41

1.01 (1.38%)

, KO

Coca-Cola

$43.35

0.28 (0.65%)

14:46
04/24/17
04/24
14:46
04/24/17
14:46
Earnings
Notable companies reporting before tomorrow's open »

Notable companies…

NVS

Novartis

$74.41

1.01 (1.38%)

KO

Coca-Cola

$43.35

0.28 (0.65%)

MMM

3M

$193.96

2.46 (1.28%)

MCD

McDonald's

$134.52

1.11 (0.83%)

LMT

Lockheed Martin

$275.72

2.63 (0.96%)

DD

DuPont

$79.69

1.04 (1.32%)

BIIB

Biogen

$272.94

0.48 (0.18%)

CAT

Caterpillar

$97.04

2.72 (2.88%)

VLO

Valero

$67.08

1.85 (2.84%)

GLW

Corning

$27.53

0.51 (1.89%)

BHI

Baker Hughes

$58.59

0.91 (1.58%)

PCAR

PACCAR

$65.76

-0.12 (-0.18%)

NTRS

Northern Trust

$87.36

-0.09 (-0.10%)

FITB

Fifth Third

$24.62

-0.33 (-1.32%)

FCX

Freeport McMoRan

$12.51

0.275 (2.25%)

NLSN

Nielsen

$41.66

0.66 (1.61%)

CNC

Centene

$72.16

1.52 (2.15%)

PHM

PulteGroup

$23.06

-0.26 (-1.11%)

JBLU

JetBlue

$21.53

0.14 (0.65%)

XRX

Xerox

$7.01

0.09 (1.30%)

PII

Polaris Industries

$83.16

1.3 (1.59%)

AN

AutoNation

$43.91

1.1 (2.57%)

GPK

Graphic Packaging

$13.52

-0.025 (-0.18%)

RAD

Rite Aid

$3.76

-0.045 (-1.18%)

TUP

Tupperware Brands

$65.58

1.355 (2.11%)

EAT

Brinker

$45.67

1.01 (2.26%)

AKS

AK Steel

$7.15

0.425 (6.32%)

SVU

Supervalu

$3.86

0.02 (0.52%)

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TEF

Telefonica

$11.38

0.48 (4.40%)

14:45
04/24/17
04/24
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14:45
Periodicals
Telefonica eyes possible IPO of O2 as early as year end, Bloomberg says »

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TMUS

T-Mobile

$64.70

-0.11 (-0.17%)

, ESRX

Express Scripts

$66.46

-0.59 (-0.88%)

14:45
04/24/17
04/24
14:45
04/24/17
14:45
Earnings
Notable companies reporting after market close »

Notable companies…

TMUS

T-Mobile

$64.70

-0.11 (-0.17%)

ESRX

Express Scripts

$66.46

-0.59 (-0.88%)

CCI

Crown Castle

$94.37

-1.165 (-1.22%)

AMP

Ameriprise

$132.30

3.86 (3.01%)

NEM

Newmont Mining

$34.05

-0.08 (-0.23%)

CDNS

Cadence Design

$32.88

0.11 (0.34%)

ZION

Zions Bancorp

$40.85

-0.23 (-0.56%)

RRC

Range Resources

$27.55

0.075 (0.27%)

AA

Alcoa

$32.86

1.16 (3.66%)

CR

Crane

$77.98

1.44 (1.88%)

OI

Owens-Illinois

$21.35

0.84 (4.10%)

SLCA

U.S. Silica

$41.60

1.09 (2.69%)

SWFT

Swift Transportation

$25.31

0.93 (3.81%)

RMBS

Rambus

$12.94

-0.07 (-0.54%)

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NTAP

NetApp

$39.49

-0.82 (-2.03%)

14:42
04/24/17
04/24
14:42
04/24/17
14:42
Recommendations
NetApp analyst commentary  »

SolidFire CEO departure…

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  • 12

    Jun

VALE

Vale

$8.78

0.1962 (2.29%)

14:31
04/24/17
04/24
14:31
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14:31
Options
4K VALE Apr 28th 9 calls trade for 14c »

4K VALE Apr 28th 9 calls…

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MCD

McDonald's

$134.32

0.91 (0.68%)

14:30
04/24/17
04/24
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04/24/17
14:30
Hot Stocks
McDonald's USA launches new uniforms »

McDonald's USA…

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  • 25

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SRPT

Sarepta

$32.61

0.07 (0.22%)

14:26
04/24/17
04/24
14:26
04/24/17
14:26
Recommendations
Sarepta analyst commentary  »

Sarepta drugs get FDA…

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MET

MetLife

$52.09

0.822 (1.60%)

14:21
04/24/17
04/24
14:21
04/24/17
14:21
Options
Metlife calls active driven by spread trading »

Metlife calls active…

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$NSD

NASDAQ Market Internals

14:17
04/24/17
04/24
14:17
04/24/17
14:17
Technical Analysis
NASDAQ market internals summary »

Volume is average for…

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$NYE

NYSE Market Internals

14:16
04/24/17
04/24
14:16
04/24/17
14:16
Technical Analysis
NYSE market internals summary »

Volume is average for…

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UCTT

Ultra Clean

$16.11

0.01 (0.06%)

14:15
04/24/17
04/24
14:15
04/24/17
14:15
Hot Stocks
Breaking Hot Stocks news story on Ultra Clean »

Ultra Clean rallies 4%,…

03/08/13
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PPG

PPG

$107.50

1.56 (1.47%)

, AKZOY

AkzoNobel

$27.96

-0.11 (-0.39%)

14:10
04/24/17
04/24
14:10
04/24/17
14:10
Hot Stocks
Elliott continues to recommend AkzoNobel engage with PPG »

Elliott, a private…

PPG

PPG

$107.50

1.56 (1.47%)

AKZOY

AkzoNobel

$27.96

-0.11 (-0.39%)

03/08/13
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SQ

Square

$17.78

0.2916 (1.67%)

14:08
04/24/17
04/24
14:08
04/24/17
14:08
Periodicals
Square acquires Yik Yak team for under $3M, Bloomberg says »

Square has taken over the…

03/08/13
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ARNC

Arconic

$26.13

0.13 (0.50%)

14:07
04/24/17
04/24
14:07
04/24/17
14:07
Hot Stocks
Arconic postpones annual meeting amid talks with Elliott »

Arconic announced that it…

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  • 25

    Apr

DIS

Disney

$113.93

-0.515 (-0.45%)

, SBGI

Sinclair Broadcast

$39.90

-0.45 (-1.12%)

14:06
04/24/17
04/24
14:06
04/24/17
14:06
Hot Stocks
Disney says signs over 160 ABC stations to over-the-top clearinghouse effort »

Disney (DIS) ABC…

DIS

Disney

$113.93

-0.515 (-0.45%)

SBGI

Sinclair Broadcast

$39.90

-0.45 (-1.12%)

SSP

E.W. Scripps

$22.15

-0.04 (-0.18%)

TGNA

Tegna

$25.70

-0.13 (-0.50%)

03/08/13
Wedge Partners
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03/06/13
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03/06/13
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