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ACAD

ACADIA

$26.99

-0.66 (-2.39%)

09:02
12/01/16
12/01
09:02
12/01/16
09:02

ACADIA initiates Phase II Pimavanserin trial for MDD

ACADIA Pharmaceuticals announced the initiation of CLARITY, a Phase II study to evaluate pimavanserin for adjunctive treatment in patients with major depressive disorder who have an inadequate response to first-line therapies for clinical depression. Pimavanserin is a selective serotonin inverse agonist preferentially targeting 5-HT2A receptors that may play a role in depression. CLARITY is a Phase II, 10-week, randomized, double-blind, placebo-controlled, multi-center study designed to examine the efficacy and safety of adjunctive use of pimavanserin in patients with major depressive disorder who have an inadequate response to standard antidepressant therapy with either a selective serotonin reuptake inhibitor or a serotonin norepinephrine reuptake inhibitor. Approximately 188 patients will be randomized to receive either 34 mg of pimavanserin or placebo, orally, once daily, in addition to their ongoing antidepressant for 10 weeks. The primary endpoint of the study is the change from baseline on the Hamilton Depression Rating Scale total score.

  • 01

    Dec

  • 02

    Dec

ACAD ACADIA
$26.99

-0.66 (-2.39%)

11/08/16
11/08/16
UPGRADE
Target $35

Buy
ACADIA upgraded to Buy, Nuplazid sales ahead of estimates, says BofA/Merrill
As previously reported, BofA/Merrill upgraded ACADIA to Buy from Neutral. Analyst Tazeen Ahmad said ACADIA reported Q3 Nuplazid sales of $5.3M, above his $2M estimate and consensus of $2.7M. Ahmad sees meaningful upside supported by management's comments that the upcoming Alzheimer Psychosis trial may not need to be statistically significant to warrant advancement. The analyst lowered his price target to $35 from $39 to reflect raised opex estimates and a smaller EU market.
11/08/16
11/08/16
UPGRADE

On The Fly: Top five analyst upgrades
Catch up on today's top five analyst upgrades with this list compiled by The Fly: 1. Sysco (SYY) upgraded to Buy from Neutral at BofA/Merrill with analyst Marisa Sullivan citing greater accretion from the Brakes acquisition in fiscal 2017. 2. Windstream (WIN) upgraded to Outperform from Market Perform at Cowen. 3. ACADIA (ACAD) upgraded to Buy from Neutral at BofA/Merrill with analyst Tazeen Ahmad seeing meaningful upside supported by management's comments that the upcoming Alzheimer Psychosis trial may not need to be statistically significant to warrant advancement. 4. Ferrari (RACE) upgraded to Hold from Sell at Evercore ISI with analyst George Galliers citing the LaFerrari Aperta coming to market sooner than expected and incremental contribution and the somewhat defensive nature of the stock. 5. Energy Transfer Equity (ETE) upgraded to Outperform from Market Perform at Bernstein with analyst Jean Ann Salisbury saying Energy Transfer's stock is trading as though the company's Dakota Access and Rover projects will be canceled. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
11/11/16
GSCO
11/11/16
INITIATION
Target $28
GSCO
Neutral
ACADIA initiated with a Neutral at Goldman
Goldman analyst Salveen Richter initiated ACADIA with a Natural and a $28 price target citing an expected gradual launch of its sole drug Nuplazid for Parkinson's disease psychosis due to limited physician disease awareness.
11/11/16
11/11/16
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Aegerion (AEGN) resumed with a Neutral at JPMorgan. 2. Lamb Weston (LW) initiated with a Buy at Stifel, initiated with an Overweight at Barclays, and an Equal Weight at Morgan Stanley. 3. bluebird bio (BLUE) initiated with a Market Perform at BMO Capital. 4. Alder Biopharmaceuticals (ALDR) initiated with an Outperform at BMO Capital. 5. ACADIA (ACAD) initiated with a Neutral at Goldman. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.

TODAY'S FREE FLY STORIES

AAN

Aaron's

$38.83

-0.39 (-0.99%)

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MDC

M.D.C. Holdings

$31.73

0.11 (0.35%)

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VSAR

Versartis

$21.60

-0.25 (-1.14%)

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IART

Integra LifeSciences

$48.31

-0.58 (-1.19%)

17:05
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  • 25

    Sep

TIF

Tiffany

$89.85

-0.08 (-0.09%)

, RL

Ralph Lauren

$88.48

-0.63 (-0.71%)

17:04
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Hot Stocks
Tiffany names Roger Farah as Chairman of Board, effective October 2 »

Tiffany & Co. (TIF)…

TIF

Tiffany

$89.85

-0.08 (-0.09%)

RL

Ralph Lauren

$88.48

-0.63 (-0.71%)

M

Macy's

$21.16

-0.32 (-1.49%)

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  • 03

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  • 04

    Oct

VSAR

Versartis

$21.60

-0.25 (-1.14%)

17:00
09/21/17
09/21
17:00
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17:00
Hot Stocks
Breaking Hot Stocks news story on Versartis 

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FLS

Flowserve

$42.19

-0.19 (-0.45%)

16:57
09/21/17
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Hot Stocks
Flowserve appoints Lee Eckert as CFO »

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AIG

AIG

$60.50

0.38 (0.63%)

16:57
09/21/17
09/21
16:57
09/21/17
16:57
Periodicals
Regulators weigh removing SIFI 'tag' from insurer AIG, Dow Jones says »

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ACM

Aecom

$34.94

-0.06 (-0.17%)

16:54
09/21/17
09/21
16:54
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16:54
Hot Stocks
Aecom announces capital allocation policy and $1B stock repurchase authorization »

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ALOG

Analogic

$79.95

2.35 (3.03%)

16:49
09/21/17
09/21
16:49
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Analogic achieves ECAC standard C2 for new cabin baggage screening solution »

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CMP

Compass Minerals

$69.50

-0.45 (-0.64%)

16:39
09/21/17
09/21
16:39
09/21/17
16:39
Earnings
Compass Minerals lowers FY17 EPS view to $2.50-$2.80 from $3.00-$3.50 »

Consensus is $3.02. The…

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  • 29

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    Sep

MDU

MDU Resources

$26.21

-0.19 (-0.72%)

16:39
09/21/17
09/21
16:39
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16:39
Hot Stocks
MDU Resources names Jason Vollmer CFO, Stephanie Barth CAO »

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16:36
09/21/17
09/21
16:36
09/21/17
16:36
General news
Money Supply M2 Weekly Change data reported »

Week of 9/11 Money Supply…

16:36
09/21/17
09/21
16:36
09/21/17
16:36
General news
Fed Balance Sheet Level data reported »

Week of 9/20 Fed Balance…

TXN

Texas Instruments

$86.05

0.22 (0.26%)

16:35
09/21/17
09/21
16:35
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16:35
Hot Stocks
Texas Instruments raises dividend 24%, adds to repurchase program »

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VSAR

Versartis

$21.60

-0.25 (-1.14%)

16:34
09/21/17
09/21
16:34
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16:34
Hot Stocks
Versartis' somavaratan did not meet primary endpoint in Phase 3 trial »

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FMC

FMC Corporation

$90.44

-1.51 (-1.64%)

, DWDP

DowDuPont

$70.32

-0.09 (-0.13%)

16:34
09/21/17
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Hot Stocks
FMC Corporation cleared for proposed acquisition of DuPont Crop Protection unit »

FMC Corporation (FMC)…

FMC

FMC Corporation

$90.44

-1.51 (-1.64%)

DWDP

DowDuPont

$70.32

-0.09 (-0.13%)

03/08/13
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  • 07

    Nov

MCD

McDonald's

$159.03

-0.85 (-0.53%)

16:32
09/21/17
09/21
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16:32
Hot Stocks
McDonald's increases quarterly dividend 7% »

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  • 25

    Sep

16:30
09/21/17
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16:30
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16:30
Options
Preliminary option volume of 13.2M today »

Preliminary option volume…

TGI

Triumph Group

$27.85

-0.2 (-0.71%)

, BA

Boeing

$256.04

0.58 (0.23%)

16:27
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Hot Stocks
Triumph Group signs contract extensions with Boeing for ducting, floor panels »

Triumph Group (TGI)…

TGI

Triumph Group

$27.85

-0.2 (-0.71%)

BA

Boeing

$256.04

0.58 (0.23%)

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  • 23

    Sep

YOGA

YogaWorks

$4.00

-0.04 (-0.99%)

16:25
09/21/17
09/21
16:25
09/21/17
16:25
Earnings
YogaWorks sees Q3 revenue $12.7M-$13.2M, consensus $12.9M »

For the third quarter of…

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  • 21

    Sep

VSAR

Versartis

$21.60

-0.25 (-1.14%)

16:25
09/21/17
09/21
16:25
09/21/17
16:25
Hot Stocks
Breaking Hot Stocks news story on Versartis »

Versartis trading halted,…

03/08/13
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YOGA

YogaWorks

$4.00

-0.04 (-0.99%)

16:22
09/21/17
09/21
16:22
09/21/17
16:22
Earnings
YogaWorks reports Q2 adjusted net loss $3.1M vs. adjusted net loss $2.7M in Q216 »

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  • 21

    Sep

CSII

Cardiovascular Systems

$27.63

0.38 (1.39%)

16:20
09/21/17
09/21
16:20
09/21/17
16:20
Initiation
Cardiovascular Systems initiated  »

Cardiovascular Systems…

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VIX

Volatility Index S&P 500 Options

16:20
09/21/17
09/21
16:20
09/21/17
16:20
Options
Closing CBOE SPX and VIX Index summary for September 21st »

The CBOE Volatility Index…

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