Breaking News Instant updates and real-time market news.

2017-05-17 06:37:35 ALNY Alnylam $72.01 6.01 (9.11%) , IONS Ionis Pharmaceuticals $44.94 1.04 (2.37%) 06:37 05/17/17 05/17 06:37 05/17/17 06:37	Alnylam price target raised to $80 from $75 at Ladenburg Ladenburg Thalmann analyst Christopher James raised his price target for Alnylam (ALNY) to $80 saying the NEURO-TTR data reported by Ionis Pharmaceuticals (IONS) are "quite positive" for patisiran and the upcoming APOLLO readout. The analyst reiterates a Buy rating on Alnylam shares. ALNY Alnylam $72.01 6.01 (9.11%) IONS Ionis Pharmaceuticals $44.94 1.04 (2.37%)	18 May 22 May 24 May 06 Jun
ALNY IONS ALNY Alnylam $72.01 6.01 (9.11%) 05/16/17 PIPR 05/16/17 NO CHANGE Target $69 PIPR Overweight Piper Jaffray sees positive readthrough for Prothena from Ionis data Piper Jaffray analyst Steven Breazzano argues that investors should "take a closer look" at Prothena (PRTA) and its PRX004 product following the recent amyloid neuropathy data from Ionis Pharmaceuticals (IONS). Prothena's candidate is expected to enter the clinic in early 2018, and Breazzano argues that there is "room for differentiation" in the space, as the drug clears the protein buildup that characterizes amyloidosis rather than directly shutting off production, as with Ionis and Alnylam's (ALNY) approaches. "At a minimum," the analyst says, a deposit-clearing approach would be complementary to production-stopping drugs. Breazzano reiterates an Overweight rating on Prothena. 05/16/17 LEER 05/16/17 NO CHANGE Target $67 LEER Outperform Alnylam price target raised to $67 from $53 at Leerink Leerink analyst Paul Matteis expects yesterday's data from Ionis Pharmaceuticals (IONS) will put TTRrx at a commercial disadvantage to Alnylam's (ALNY) patisiran. The top-line results for TTRrx, which showed high efficacy and several safety issues, is the best case for Alnylam, Matteis tells investors in a research note. He raised his odds of approval for both programs but lowered his price target for Ionis to $45 from $47. Matteis has Market Perform ratings on both stocks. 05/16/17 FBCO 05/16/17 NO CHANGE Target $90 FBCO Outperform Alnylam price target raised to $90 after Ionis data at Credit Suisse Credit Suisse analyst Alethia Young said her conviction that Alnylam (ALNY) will be successful in its Phase 3 familial amyloid polyneuropathy trial has been increased following the data reported by competitor Ionis (IONS). She is also adjusting her market share estimates for their two FAP drugs, modeling the market split to be 70% in favor of Alnylam's patisiran and 30% for Ionis' inotersen, as she believes patisiran will have a better safety profile. Young raised her price target on Alnylam shares to $90 from $50 and keeps an Outperform rating on the stock, which gained 16% yesterday to close at $66. 05/15/17 CHDN 05/15/17 NO CHANGE Target $110 CHDN Buy Alnylam price target raised to $110 from $95 at Chardan IONS Ionis Pharmaceuticals $44.94 1.04 (2.37%) 05/16/17 RHCO 05/16/17 NO CHANGE RHCO Prothena has positive read through from Ionis safety issues, says SunTrust SunTrust analyst Yun Zhong says that safety issues with Ionis' inotersen during a Phase III trial are positive for Prothena. The analyst says that Prothena's new drug, PRX004, could have a better safety profile than its previous drug, NEOD001,. He notes that PRX004 has a different mechanism of action than Ionis' drug, and he thinks the discrepancy could enable Prthena's drug to have a better safety profile. He keeps a Buy rating on Prothena.

2017-05-17 06:37:35

ALNY

Alnylam

$72.01: 6.01 (9.11%)

, IONS

Ionis Pharmaceuticals

$44.94: 1.04 (2.37%)

06:37

05/17/17

05/17

06:37

05/17/17

06:37

Alnylam price target raised to $80 from $75 at Ladenburg

Ladenburg Thalmann analyst Christopher James raised his price target for Alnylam (ALNY) to $80 saying the NEURO-TTR data reported by Ionis Pharmaceuticals (IONS) are "quite positive" for patisiran and the upcoming APOLLO readout. The analyst reiterates a Buy rating on Alnylam shares.

ALNY

Alnylam

$72.01: 6.01 (9.11%)

IONS

Ionis Pharmaceuticals

$44.94: 1.04 (2.37%)

18
May
22
May
24
May
06
Jun

ALNY
IONS

ALNY Alnylam

$72.01: 6.01 (9.11%)

05/16/17: PIPR

05/16/17: LEER

05/16/17: FBCO

05/15/17: CHDN

IONS Ionis Pharmaceuticals

$44.94: 1.04 (2.37%)

05/16/17: RHCO

TODAY'S FREE FLY STORIES

EXAS Exact Sciences $32.65 -0.67 (-2.01%) , UNH UnitedHealth $176.59 -0.91 (-0.51%) 07:31 05/31/17 05/31 07:31 05/31/17 07:31 Recommendations	Exact Sciences, UnitedHealth analyst commentary » Exact Sciences remains a… EXAS Exact Sciences $32.65 -0.67 (-2.01%) UNH UnitedHealth $176.59 -0.91 (-0.51%) Story temporarily locked. To read stories as they happen please subscribe, Login above, or return in in 9 minutes Get Free Trial 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial	31 May 31 May 06 Jun
QCOM Qualcomm $57.34 -0.18 (-0.31%) , NXPI NXP Semiconductors $108.14 0.14 (0.13%) 07:31 05/31/17 05/31 07:31 05/31/17 07:31 Hot Stocks	Qualcomm extends cash tender offer for NXP Semiconductors outstanding shares » Qualcomm (QCOM) announced… QCOM Qualcomm $57.34 -0.18 (-0.31%) NXPI NXP Semiconductors $108.14 0.14 (0.13%) Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial	01 Jun 09 Jun
FRO Frontline $5.41 -0.22 (-3.91%) 07:31 05/31/17 05/31 07:31 05/31/17 07:31 Upgrade	Frontline rating change » Frontline upgraded to Buy… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return in in 9 minutes Get Free Trial 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial
EGHT 8x8, Inc. $13.60 0.1 (0.74%) 07:30 05/31/17 05/31 07:30 05/31/17 07:30 Conference/Events	8x8, Inc. management to meet with Needham » Meeting to be held in… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial	31 May 01 Jun 06 Jun 06 Jun 08 Jun 13 Jun
GNRT Gener8 Maritime $4.91 0.06 (1.24%) , FRO Frontline $5.41 -0.22 (-3.91%) … 07:30 05/31/17 05/31 07:30 05/31/17 07:30 Recommendations	Gener8 Maritime, Frontline, DHT Holdings analyst commentary » Gener8 Maritime advance… GNRT Gener8 Maritime $4.91 0.06 (1.24%) FRO Frontline $5.41 -0.22 (-3.91%) DHT DHT Holdings $4.20 -0.07 (-1.64%) Story temporarily locked. To read stories as they happen please subscribe, Login above, or return in in 9 minutes Get Free Trial 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial

WLL Whiting Petroleum $7.28 -0.69 (-8.66%) , ORCL Oracle $45.42 0.16 (0.35%) 07:30 05/31/17 05/31 07:30 05/31/17 07:30 Options	Unusual put flow in option market yesterday » Notable put activity was… WLL Whiting Petroleum $7.28 -0.69 (-8.66%) ORCL Oracle $45.42 0.16 (0.35%) Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial
KORS Michael Kors $36.27 -0.49 (-1.33%) 07:25 05/31/17 05/31 07:25 05/31/17 07:25 Technical Analysis	Technical View: Michael Kors drops to new 52-week low after earnings » In the pre-market the… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return in in 9 minutes Get Free Trial 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial	31 May
CBS CBS $61.52 -0.05 (-0.08%) , CBS.A $63.50 -0.15 (-0.24%) … 07:24 05/31/17 05/31 07:24 05/31/17 07:24 Periodicals	Scott Pelley to depart anchor role on 'CBS Evening News,' NY Times says » CBS (CBS, CBS.A) news… CBS CBS $61.52 -0.05 (-0.08%) CBS.A $63.50 -0.15 (-0.24%) CMCSA Comcast $41.10 0.19 (0.46%) CMCSK Comcast DIS Disney $108.34 -0.07 (-0.06%) Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial	01 Jun 08 Jun 15 Jun
KORS Michael Kors $36.27 -0.49 (-1.33%) 07:23 05/31/17 05/31 07:23 05/31/17 07:23 Hot Stocks	Breaking Hot Stocks news story on Michael Kors » Michael Kors drops 7% in… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return in in 9 minutes Get Free Trial 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial	31 May
UAA Under Armour $19.56 -0.13 (-0.66%) 07:23 05/31/17 05/31 07:23 05/31/17 07:23 Recommendations	Under Armour analyst commentary » Under Armour has reached… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial	31 May

07:22 05/31/17 05/31 07:22 05/31/17 07:22 General news	Futures higher ahead of final trading for May » Stock futures are above… Stock futures are above fair value as the final trading session of May is set to begin. World markets closed trading with gains for the month as investors stateside will be looking ahead to Friday's nonfarm payrolls report. Today though they will see the Chicago purchasing manager's report and pending home sales data. The weekly oil numbers, which are normally released on Wednesday, will be delayed until tomorrow due to the Memorial Day holiday. In early trading, Dow futures are 18 points above fair value, Nasdaq futures are 12 points above fair value and S&P futures are 2 points above fair value.
KORS Michael Kors $36.27 -0.49 (-1.33%) 07:22 05/31/17 05/31 07:22 05/31/17 07:22 Hot Stocks	Michael Kors says to close 100-125 full-price retail stores over next two years » Michael Kors announced… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return in in 9 minutes Get Free Trial 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial	31 May
MYL Mylan $39.36 -0.36 (-0.91%) 07:19 05/31/17 05/31 07:19 05/31/17 07:19 Recommendations	Mylan analyst commentary » Pension fund campaign a… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial	03 Sep 09 Oct
VIAB Viacom $35.05 -0.08 (-0.23%) , VIA Viacom $38.90 0.5 (1.30%) 07:17 05/31/17 05/31 07:17 05/31/17 07:17 Recommendations	Viacom, Viacom analyst commentary » Viacom price target… VIAB Viacom $35.05 -0.08 (-0.23%) VIA Viacom $38.90 0.5 (1.30%) Story temporarily locked. To read stories as they happen please subscribe, Login above, or return in in 9 minutes Get Free Trial 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial
XXII 22nd Century $1.37 -0.02 (-1.44%) 07:17 05/31/17 05/31 07:17 05/31/17 07:17 Hot Stocks	22nd Century reports 'dramatic surge' in VLN tobacco clinical trials, science » 22nd Century Group… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial

ABT Abbott $45.00 0.29 (0.65%) 07:16 05/31/17 05/31 07:16 05/31/17 07:16 Recommendations	Abbott analyst commentary » Abbott making progress, … Story temporarily locked. To read stories as they happen please subscribe, Login above, or return in in 9 minutes Get Free Trial 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial
GRMN Garmin $52.11 -0.29 (-0.55%) 07:15 05/31/17 05/31 07:15 05/31/17 07:15 Hot Stocks	Garmin launches Approach S60 golf watch » Garmin International… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial
SLCA U.S. Silica $36.45 -0.76 (-2.04%) 07:15 05/31/17 05/31 07:15 05/31/17 07:15 Technical Analysis	Technical View: U.S. Silica trades higher in pre-market » In the pre-market the… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return in in 9 minutes Get Free Trial 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial	20 Jun
GPRK GeoPark $8.71 -0.18 (-2.02%) 07:12 05/31/17 05/31 07:12 05/31/17 07:12 Hot Stocks	GeoPark names Coulter Enterprises Chairman and CEO Coulter to board » GeoPark Limited announced… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial
PRQR ProQR Therapeutics $4.70 -0.3 (-6.00%) 07:12 05/31/17 05/31 07:12 05/31/17 07:12 Hot Stocks	ProQR Therapeutics' QR-110 granted Fast Track designation by FDA » ProQR Therapeutics… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return in in 9 minutes Get Free Trial 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial

MOH Molina Healthcare $66.30 -0.57 (-0.85%) 07:11 05/31/17 05/31 07:11 05/31/17 07:11 Downgrade	Molina Healthcare rating change » Molina Healthcare… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial
GSK GlaxoSmithKline $43.41 0.74 (1.73%) 07:11 05/31/17 05/31 07:11 05/31/17 07:11 Technical Analysis	Technical View: GlaxoSmithKline rises in early trading » Shares were last up over… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return in in 9 minutes Get Free Trial 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial	06 Jun
RGNX Regenxbio $16.70 -1.3 (-7.22%) 07:09 05/31/17 05/31 07:09 05/31/17 07:09 Earnings	Regenxbio initiates Phase 1 clinical trial of RGX-314 for macular degeneration » Regenxbio has dosed the… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial
INCY Incyte $130.49 -3.89 (-2.89%) 07:08 05/31/17 05/31 07:08 05/31/17 07:08 Recommendations	Incyte analyst commentary » Incyte price target… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return in in 9 minutes Get Free Trial 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial	02 Jun 13 Jun 15 Jun
TRIL Trillium Therapeutics $5.05 0.05 (1.00%) 07:08 05/31/17 05/31 07:08 05/31/17 07:08 Hot Stocks	Trillium to present TTI-621 immune checkpoint inhibitor program at ASCO » Trillium Therapeutics… Story temporarily locked. To read stories as they happen please subscribe, Login above, or return tomorrow Get Free Trial 03/08/13 Wedge Partners 03/08/13 Credit Suisse 03/06/13 Citigroup 03/06/13 Barclays See Street Research during your Free Trial

Events

Earnings calls, analyst events, roadshows and more

Today at 08:00

Fed Bank President Kaplan Takes Part in a Discussion Government Event

New York, NY
JILL
Today at 08:00

J.Jill - JILL Conference Calls
KORS
Today at 08:00

Michael Kors - KORS Conference Calls
BWFG
Today at 08:00

Bankwell Financial Firm Sponsored Meetings

Woodway Country Club--540 Hoyt Street, Darien, CT
CUBE
Today at 08:00

CubeSmart Firm Sponsored Meetings

Co Offices--5 Old Lancaster Road, Malvern, PA
SCOR
Today at 08:30

comScore - SCOR Conference Calls
PRGO
Today at 08:30

Perrigo - PRGO Conference Calls
NVS
Today at 08:30

Novartis Firm Sponsored Meetings
ONCE
Today at 08:30

Spark Therapeutics Firm Sponsored Meetings

Offices of Ballard Spahr LLP--1735 Market Street, Philadelphia, PA
Today at 08:55

Redbook Store Sales Y/Y: Week 5/27 Government Event

View All Events »

1 of

Syndicate

This week’s upcoming IPOs and secondary offerings

Priced
Not Priced

Mon	No deals
Tues	No deals
Wed	No deals
Thurs	No deals
Fri	No deals

Mon	No deals
Tues	ARI X ARI Apollo Commercial Spot Secondary Managers: Citi, JPMorgan, BofA/Merrill & Morgan Stanley $18.25-18.60 1.2M Shares JRVR X JRVR James River Group Spot Secondary Managers: Morgan Stanley $40.00-41.00 4.25M Shares STAY X STAY Extended Stay America Spot Secondary Managers: Morgan Stanley & Citi $17.50-17.60 2.5B Shares
Wed	No deals
Thurs	No deals
Fri	No deals

View All Syndicate Announcements »

Alnylam price target raised to $80 from $75 at Ladenburg

TODAY'S FREE FLY STORIES

Get Full Fly Access