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AZN

AstraZeneca

$33.97

-0.055 (-0.16%)

12:37
05/19/17
05/19
12:37
05/19/17
12:37

AstraZeneca announces positive CHMP opinion for brodalumab

AstraZeneca announced that its partner LEO Pharma has received a positive opinion from the Committee for Medicinal Products for Human Us eof the European Medicines Agency recommending the approval of brodalumab for the treatment of adult patients with moderate-to-severe plaque psoriasis who are candidates for systemic therapy. Brodalumab is the first and only fully human monoclonal antibody that selectively targets the IL-17 receptor. By binding to the receptor, brodalumab effectively blocks the biological activity of several pro-inflammatory IL-17 cytokines, which are important in psoriasis, a chronic, debilitating skin disease that causes red patches of skin covered with silvery scales. In July 2016, AstraZeneca announced an agreement granting LEO Pharma exclusive rights to develop and commercialise brodalumab in Europe. The announcement follows the approval of brodalumab by the US Food and Drug Administration in February 2017 and the approval by the Japanese Pharmaceuticals and Medical Devices Agency in 2016. The CHMP's positive opinion on brodalumab will now be reviewed by the European Commission, which has the authority to approve medicines for the European Union.The final decision is applicable to all EU and European Economic Area countries. Reference Link

  • 19

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AZN AstraZeneca
$33.97

-0.055 (-0.16%)

05/17/17
JPMS
05/17/17
UPGRADE
Target $72
JPMS
Overweight
Clovis upgraded to Overweight from Neutral at JPMorgan
JPMorgan analyst Cory Kasimov upgraded Clovis Oncology (CLVS) to Overweight and raised his price target for the shares to $72 from $58. The stock closed yesterday up 2%, or $1.05, to $49.56. The shares are down 35% over the last two months for "no clear fundamental reason," Kasimov tells investors in a research note. The analyst is "increasingly comfortable" recommending Clovis ahead of its Phase 3 study evaluating Rubraca in maintenance ovarian cancer now that more PARP class data has emerged. He has not seen "convincing evidence" that there is a clear efficacy difference between Clovis' rucaparib, Tesaro's (TSRO) niraparib and AstraZeneca's (AZN) olaparib.
05/16/17
LEER
05/16/17
NO CHANGE
Target $36
LEER
Outperform
AstraZeneca price target raised to $36 from $33 at Leerink
Leerink analyst Seamus Fernandez raised his price target for AstraZeneca to $36 after hosting a call with a lung cancer specialist. The specialist believes that once approved, the uptake of AstraZeneca's Imfinzi in Stage III unresectable non-small cell lung cancer will be "significant" given the poor outcomes and general lack of an effective treatment standard in this setting, Fernandez tells investors in a research note. The analyst raised his peak worldwide forecasts for the drug by $1B and keeps an Outperform rating on AstraZeneca.
05/15/17
LEER
05/15/17
NO CHANGE
LEER
GlaxoSmithKline possible move to buyout Novartis stake makes sense, says Leerink
Leerink analyst Seamus Fernandez is not surprised by the news that GlaxoSmithKline (GSK) may buyout Novartis' (NVS) 36.5% stake in its Consumer Healthcare joint venture through a GBP8B deal sooner rather than later. The analyst believes this buyout could be beneficial as the infusion of additional cash from the buyout could bolster Novartis appetite for large scale M&A, including companies such as AstraZeneca (AZN) whose immune-oncology assets could complement its small-molecule focused oncology portfolio, according to the London Times.
05/12/17
05/12/17
UPGRADE

Neutral
AstraZeneca upgraded to Neutral at Credit Suisse
As previously reported, Credit Suisse analyst Rebekah Harper upgraded AstraZeneca to Neutral from Underperform after the company reported surprise positive headline results from the Phase 3 PACIFIC trial for Imfinzi in stage 3 unresectable lung cancer in all-comers, with positive progression free survival data. The analyst believes that AstraZeneca is in a "unique position" with this indication, with a likely two to three years lead versus competitors, as other P3s are not due until 2020+. Harper expects U.S. approval for AstraZeneca in this indication before the end of 2017.

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PCTY

Paylocity

$45.10

-1.06 (-2.30%)

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Paychex

$54.98

-1.26 (-2.24%)

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Paylocity announces Michael Haske's promotion to president & COO »

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Paychex

$54.98

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ADP

ADP

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SN

Sanchez Energy

$4.87

-0.145 (-2.89%)

18:04
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Sanchez Energy to sell Javelina asset in Eagle Ford shale for about $105M »

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BABA

Alibaba

$163.92

4.42 (2.77%)

17:50
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Alibaba analyst commentary  »

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ASYS

Amtech Systems

$10.14

-0.51 (-4.79%)

17:48
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17:48
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17:48
Syndicate
Amtech Systems announces common stock offering, no amount given »

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CPCAY

Cathay Pacific

$7.47

0.15 (2.05%)

17:47
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17:47
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17:47
Upgrade
Cathay Pacific rating change  »

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RTN

Raytheon

$177.25

-0.83 (-0.47%)

17:32
08/17/17
08/17
17:32
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17:32
Hot Stocks
Raytheon awarded $104.8M government contract »

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SPWH

Sportsman's Warehouse

$3.46

-0.12 (-3.35%)

, GLOB

Globant

$42.26

-0.64 (-1.49%)

17:32
08/17/17
08/17
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17:32
Hot Stocks
On The Fly: After Hours Movers »

UP AFTER EARNINGS:…

SPWH

Sportsman's Warehouse

$3.46

-0.12 (-3.35%)

GLOB

Globant

$42.26

-0.64 (-1.49%)

ROST

Ross Stores

$53.33

-1.04 (-1.91%)

GPS

Gap

$22.68

0.11 (0.49%)

AMAT

Applied Materials

$43.12

-1.34 (-3.01%)

FLDM

Fluidigm

$3.60

-0.04 (-1.10%)

SENS

Senseonics

$2.44

0.02 (0.83%)

03/08/13
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LMT

Lockheed Martin

$301.42

-4.38 (-1.43%)

17:32
08/17/17
08/17
17:32
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17:32
Hot Stocks
Lockheed Martin, others awarded $499M government contract »

Lockheed Martin, Fort…

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  • 23

    Aug

CTRL

Control4

$22.27

-0.9 (-3.88%)

, AMRI

Albany Molecular

$21.74

-0.01 (-0.05%)

17:21
08/17/17
08/17
17:21
08/17/17
17:21
Hot Stocks
Control4 to replace Albany Molecular in S&P 600 at open on 8/22 »

The Carlyle Group (CG)…

CTRL

Control4

$22.27

-0.9 (-3.88%)

AMRI

Albany Molecular

$21.74

-0.01 (-0.05%)

CG

Carlyle Group

$21.20

-0.2 (-0.93%)

03/08/13
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  • 30

    Aug

CI

Cigna

$178.03

-1.83 (-1.02%)

17:15
08/17/17
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17:15
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17:15
Hot Stocks
Cigna's Bacus sells 2,236 common shares »

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  • 06

    Sep

17:09
08/17/17
08/17
17:09
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17:09
General news
Sen. Corker: Trump has not demonstrated competence to be president »

According to various…

BTU

Peabody Energy

$27.94

-0.27 (-0.96%)

17:07
08/17/17
08/17
17:07
08/17/17
17:07
Syndicate
Peabody Energy files to sell 12.8M shares of common stock for holders »

Peabody Energy announced…

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CEMI

Chembio Diagnostics

$6.05

-0.1 (-1.63%)

17:02
08/17/17
08/17
17:02
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17:02
Hot Stocks
Chembio Diagnostics CFO Richard Larkin to retire »

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CRMT

America's Car-Mart

$36.90

-0.65 (-1.73%)

17:01
08/17/17
08/17
17:01
08/17/17
17:01
Earnings
America's Car-Mart reports Q1 EPS 90c, consensus 91c »

Reports Q1 revenue $146M,…

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GM

General Motors

$35.00

-0.75 (-2.10%)

16:59
08/17/17
08/17
16:59
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16:59
Hot Stocks
General Motors' Jacoby sells 20,000 common shares »

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CBI

CB&I

$9.78

-0.19 (-1.91%)

, FLR

Fluor

$37.77

-0.67 (-1.74%)

16:59
08/17/17
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Hot Stocks
President Donald Trump shelves plans to create infrastructure advisory council »

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CBI

CB&I

$9.78

-0.19 (-1.91%)

FLR

Fluor

$37.77

-0.67 (-1.74%)

ACM

Aecom

$31.09

-0.43 (-1.36%)

MTZ

MasTec

$39.20

0.45 (1.16%)

CCI

Crown Castle

$104.14

0.35 (0.34%)

JEC

Jacobs Engineering

$50.25

-0.8 (-1.57%)

MLM

Martin Marietta

$200.41

-4.7 (-2.29%)

USCR

U.S. Concrete

$77.20

-0.9 (-1.15%)

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  • 11

    Sep

CQP

Cheniere Energy Partners

$28.08

-0.08 (-0.28%)

16:53
08/17/17
08/17
16:53
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16:53
Syndicate
Breaking Syndicate news story on Cheniere Energy Partners »

Cheniere Energy Partners…

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DDS

Dillard's

$54.83

-1.1 (-1.97%)

16:50
08/17/17
08/17
16:50
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16:50
Hot Stocks
Dillard's raises quarterly dividend to 10c from 7c per share »

The dividend is payable…

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ABTL

Autobytel

$8.30

-0.12 (-1.43%)

16:46
08/17/17
08/17
16:46
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16:46
Hot Stocks
Autobytel announces purchases under stock repurchase authorization »

Autobytel announced that…

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GBL

GAMCO Investors

$29.41

-0.4 (-1.34%)

, CMT

Core Molding

$21.07

-0.36 (-1.68%)

16:43
08/17/17
08/17
16:43
08/17/17
16:43
Hot Stocks
Breaking Hot Stocks news story on GAMCO Investors, Core Molding »

Gabelli reports 10.94%…

GBL

GAMCO Investors

$29.41

-0.4 (-1.34%)

CMT

Core Molding

$21.07

-0.36 (-1.68%)

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  • 06

    Sep

GUID

Guidance Software

16:41
08/17/17
08/17
16:41
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16:41
Hot Stocks
Breaking Hot Stocks news story on Guidance Software »

Soros Fund Management…

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GBL

GAMCO Investors

$29.41

-0.4 (-1.34%)

, MTRN

Materion

$37.00

-1.1 (-2.89%)

16:41
08/17/17
08/17
16:41
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16:41
Hot Stocks
Breaking Hot Stocks news story on GAMCO Investors, Materion »

Gabelli reports 6.66%…

GBL

GAMCO Investors

$29.41

-0.4 (-1.34%)

MTRN

Materion

$37.00

-1.1 (-2.89%)

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  • 30

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FALC

FalconStor

$0.19

-0.004 (-2.12%)

16:41
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08/17
16:41
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16:41
Hot Stocks
FalconStor announces Todd Brooks as CEO and Patrick McClain as CFO »

FalconStor announced the…

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16:36
08/17/17
08/17
16:36
08/17/17
16:36
General news
Fed Balance Sheet Level data reported »

Week of 8/16 Fed Balance…

16:36
08/17/17
08/17
16:36
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16:36
General news
Money Supply M2 Weekly Change data reported »

Week of 8/7 Money Supply…

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