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AZN

AstraZeneca

$33.97

-0.055 (-0.16%)

12:37
05/19/17
05/19
12:37
05/19/17
12:37

AstraZeneca announces positive CHMP opinion for brodalumab

AstraZeneca announced that its partner LEO Pharma has received a positive opinion from the Committee for Medicinal Products for Human Us eof the European Medicines Agency recommending the approval of brodalumab for the treatment of adult patients with moderate-to-severe plaque psoriasis who are candidates for systemic therapy. Brodalumab is the first and only fully human monoclonal antibody that selectively targets the IL-17 receptor. By binding to the receptor, brodalumab effectively blocks the biological activity of several pro-inflammatory IL-17 cytokines, which are important in psoriasis, a chronic, debilitating skin disease that causes red patches of skin covered with silvery scales. In July 2016, AstraZeneca announced an agreement granting LEO Pharma exclusive rights to develop and commercialise brodalumab in Europe. The announcement follows the approval of brodalumab by the US Food and Drug Administration in February 2017 and the approval by the Japanese Pharmaceuticals and Medical Devices Agency in 2016. The CHMP's positive opinion on brodalumab will now be reviewed by the European Commission, which has the authority to approve medicines for the European Union.The final decision is applicable to all EU and European Economic Area countries. Reference Link

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AZN AstraZeneca
$33.97

-0.055 (-0.16%)

05/12/17
05/12/17
UPGRADE

Neutral
AstraZeneca upgraded to Neutral at Credit Suisse
As previously reported, Credit Suisse analyst Rebekah Harper upgraded AstraZeneca to Neutral from Underperform after the company reported surprise positive headline results from the Phase 3 PACIFIC trial for Imfinzi in stage 3 unresectable lung cancer in all-comers, with positive progression free survival data. The analyst believes that AstraZeneca is in a "unique position" with this indication, with a likely two to three years lead versus competitors, as other P3s are not due until 2020+. Harper expects U.S. approval for AstraZeneca in this indication before the end of 2017.
05/15/17
LEER
05/15/17
NO CHANGE
LEER
GlaxoSmithKline possible move to buyout Novartis stake makes sense, says Leerink
Leerink analyst Seamus Fernandez is not surprised by the news that GlaxoSmithKline (GSK) may buyout Novartis' (NVS) 36.5% stake in its Consumer Healthcare joint venture through a GBP8B deal sooner rather than later. The analyst believes this buyout could be beneficial as the infusion of additional cash from the buyout could bolster Novartis appetite for large scale M&A, including companies such as AstraZeneca (AZN) whose immune-oncology assets could complement its small-molecule focused oncology portfolio, according to the London Times.
05/16/17
LEER
05/16/17
NO CHANGE
Target $36
LEER
Outperform
AstraZeneca price target raised to $36 from $33 at Leerink
Leerink analyst Seamus Fernandez raised his price target for AstraZeneca to $36 after hosting a call with a lung cancer specialist. The specialist believes that once approved, the uptake of AstraZeneca's Imfinzi in Stage III unresectable non-small cell lung cancer will be "significant" given the poor outcomes and general lack of an effective treatment standard in this setting, Fernandez tells investors in a research note. The analyst raised his peak worldwide forecasts for the drug by $1B and keeps an Outperform rating on AstraZeneca.
05/17/17
JPMS
05/17/17
UPGRADE
Target $72
JPMS
Overweight
Clovis upgraded to Overweight from Neutral at JPMorgan
JPMorgan analyst Cory Kasimov upgraded Clovis Oncology (CLVS) to Overweight and raised his price target for the shares to $72 from $58. The stock closed yesterday up 2%, or $1.05, to $49.56. The shares are down 35% over the last two months for "no clear fundamental reason," Kasimov tells investors in a research note. The analyst is "increasingly comfortable" recommending Clovis ahead of its Phase 3 study evaluating Rubraca in maintenance ovarian cancer now that more PARP class data has emerged. He has not seen "convincing evidence" that there is a clear efficacy difference between Clovis' rucaparib, Tesaro's (TSRO) niraparib and AstraZeneca's (AZN) olaparib.

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General news
FX Action: The dollar has been trading softer »

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MB

Mindbody

$27.95

0.1 (0.36%)

20:37
05/24/17
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Mindbody 4.4M share Secondary priced at $27.95 »

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MDT

Medtronic

$84.70

0.09 (0.11%)

, DLTR

Dollar Tree

$78.08

-0.77 (-0.98%)

20:25
05/24/17
05/24
20:25
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20:25
Earnings
Notable companies reporting before tomorrow's open »

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MDT

Medtronic

$84.70

0.09 (0.11%)

DLTR

Dollar Tree

$78.08

-0.77 (-0.98%)

HRL

Hormel Foods

$35.40

0.19 (0.54%)

BBY

Best Buy

$50.42

-1.13 (-2.19%)

SIG

Signet Jewelers

$54.53

-3.85 (-6.59%)

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WUBA

58.com

$44.02

0.36 (0.82%)

20:11
05/24/17
05/24
20:11
05/24/17
20:11
Earnings
Breaking Earnings news story on 58.com »

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  • 25

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WUBA

58.com

$44.02

0.36 (0.82%)

20:10
05/24/17
05/24
20:10
05/24/17
20:10
Earnings
58.com reports Q1 EPS 10c, consensus (25c) »

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  • 25

    May

SNAP

Snap

$20.53

0.5 (2.50%)

20:07
05/24/17
05/24
20:07
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20:07
Periodicals
Snapchat Shows outperforming internal targets, Variety says »

As part of a larger…

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EPC

Edgewell Personal Care

$72.45

0.36 (0.50%)

, PG

Procter & Gamble

$86.50

0.42 (0.49%)

19:53
05/24/17
05/24
19:53
05/24/17
19:53
Hot Stocks
Edgewell shave brand Schick launches subscription service »

Edgewell Personal Care…

EPC

Edgewell Personal Care

$72.45

0.36 (0.50%)

PG

Procter & Gamble

$86.50

0.42 (0.49%)

03/08/13
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WOW

WideOpenWest

19:49
05/24/17
05/24
19:49
05/24/17
19:49
Syndicate
WideOpenWest 18.2M share IPO priced at $17.00, below the range »

The deal size was…

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  • 24

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SFTBF

SoftBank

$76.21

-0.585 (-0.76%)

, S

Sprint

$8.17

-0.01 (-0.12%)

19:44
05/24/17
05/24
19:44
05/24/17
19:44
Hot Stocks
SoftBank nominates Sprint CEO to board »

SoftBank (SFTBF)…

SFTBF

SoftBank

$76.21

-0.585 (-0.76%)

S

Sprint

$8.17

-0.01 (-0.12%)

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SNDX

Syndax

$13.89

-0.78 (-5.32%)

19:44
05/24/17
05/24
19:44
05/24/17
19:44
Syndicate
Syndax 3.75M share Secondary priced at $13.25 »

Morgan Stanley, Citi and…

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  • 02

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JELD

JELD-WEN Holding

$31.21

0.95 (3.14%)

19:29
05/24/17
05/24
19:29
05/24/17
19:29
Syndicate
JELD-WEN Holding 14M share Secondary priced at $30.75 »

Barclays, Citi, Credit…

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  • 25

    May

CWH

Camping World

$27.87

0.19 (0.69%)

19:27
05/24/17
05/24
19:27
05/24/17
19:27
Syndicate
Camping World 9.5M share Secondary priced at $27.75 »

The deal size was…

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  • 25

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PBR

Petrobras

$9.08

0.25 (2.83%)

19:17
05/24/17
05/24
19:17
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19:17
Hot Stocks
Petrobras notified of dismissal of popular interest suit in shallow water case »

Petrobras reports that it…

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ETSY

Etsy

$13.40

0.09 (0.68%)

19:17
05/24/17
05/24
19:17
05/24/17
19:17
Periodicals
Etsy downscales intern program, Bloomberg says »

Etsy is slashing its…

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GOOG

Alphabet

$954.96

6.14 (0.65%)

, GOOGL

Alphabet Class A

$977.61

7.06 (0.73%)

19:09
05/24/17
05/24
19:09
05/24/17
19:09
Hot Stocks
Google introduces marketing measurement tool 'Ads Data Hub' »

As part of its annual…

GOOG

Alphabet

$954.96

6.14 (0.65%)

GOOGL

Alphabet Class A

$977.61

7.06 (0.73%)

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PTCT

PTC Therapeutics

$12.58

-0.92 (-6.81%)

19:04
05/24/17
05/24
19:04
05/24/17
19:04
Hot Stocks
PTC Therapeutics director Svoronos acquires 25,000 common shares »

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  • 09

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NVDA

Nvidia

$138.57

1.54 (1.12%)

, GOOG

Alphabet

$954.96

6.14 (0.65%)

19:04
05/24/17
05/24
19:04
05/24/17
19:04
Hot Stocks
NVIDIA CEO on Google AI chip: Great to see two leaders race »

In a company blog post…

NVDA

Nvidia

$138.57

1.54 (1.12%)

GOOG

Alphabet

$954.96

6.14 (0.65%)

GOOGL

Alphabet Class A

$977.61

7.06 (0.73%)

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TSO

Tesoro

$83.09

0.07 (0.08%)

19:02
05/24/17
05/24
19:02
05/24/17
19:02
Hot Stocks
Tesoro says Western Rifing deal waiting period has terminated »

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KR

Kroger

$29.13

0.01 (0.03%)

19:02
05/24/17
05/24
19:02
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19:02
Hot Stocks
Kroger recalls Yellow Sponge Cake dessert cups containing undeclared milk »

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SZEVY

Suez

$9.18

0.065 (0.71%)

18:59
05/24/17
05/24
18:59
05/24/17
18:59
Downgrade
Suez rating change at Goldman Sachs »

Suez downgraded to…

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SABR

Sabre

$23.09

0.17 (0.74%)

18:48
05/24/17
05/24
18:48
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Hot Stocks
Sabre sees approximately $80M-$100M charge associated with Air Berlin contract »

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  • 24

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CONN

Conn's

$15.40

-0.15 (-0.96%)

18:33
05/24/17
05/24
18:33
05/24/17
18:33
Hot Stocks
Conn's announces departure of Michael Poppe, COO, Credit and Collections »

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  • 31

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QDEL

Quidel

$24.62

0.01 (0.04%)

18:32
05/24/17
05/24
18:32
05/24/17
18:32
Hot Stocks
Quidel says PMDA of Japan approves Sofia Influenza A+B Assay »

Quidel announced it has…

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SBH

Sally Beauty

$17.38

-0.18 (-1.03%)

18:32
05/24/17
05/24
18:32
05/24/17
18:32
Hot Stocks
Sally Beauty CEO acquires 10,000 common shares »

In a regulatory filing,…

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