Catch up on today's top five analyst upgrades with this list compiled by The Fly: 1. Agios Pharmaceuticals (AGIO) upgraded to Buy from Hold at Canaccord and upgraded to Overweight from Neutral at JPMorgan with Canaccord analyst John Newman raising his price target for the shares to $90 from $50 and JPMorgan analyst Anupam Rama raising his price target for the shares to $62 from $50. 2. Estee Lauder (EL) upgraded to Buy from Outperform at CLSA after analyst Caroline Levy had a meeting with CEO Fabrizio Freda and CFO Tracey Travis and came away impressed by their confidence in Estee's business outlook, despite secular pressure on U.S. department stores and a shift in travel patterns by emerging market consumers. 3. NVIDIA (NVDA) upgraded to Buy from Neutral at Nomura with the firm saying it expects the company to benefit from strong secular trends, including higher gaming ASPs, and a strong datacenter outlook. 4. Aptose Biosciences (APTO) upgraded to Buy from Neutral at Roth Capital with analyst Joseph Pantginis saying the company has made a "significant" addition to its pipeline, signing an agreement with CrystalGenomics for CG-806, an inhibitor of Bruton's tyrosine kinase, FMS-like tyrosine kinase 3 and Aurora kinases. 5. Concho Resources (CXO) upgraded to Overweight from Equal Weight at Morgan Stanley with analysts led by Evan Calio citing a more constructive view on the long-term commodity outlook, raising long-term oil price assumption for Brent to $80 and upgraded the E&P industry view to Attractive. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.

Get caught up quickly on the top news and calls moving stocks with these five Top Five lists.  1... To see the rest of the story go to thefly.com. See Story Here

Get caught up quickly on the top news and calls moving stocks with these five Top Five lists. 1... To see the rest of the story go to thefly.com. See Story Here

Friday's total option volume of 58.8 million contracts resulted in net open interest growth of 5.70 million calls and 5.17 million puts. Apple (AAPL), Tesla (TSLA), NVIDIA (NVDA) and Advanced Micro Devices (AMD) saw the greatest growth. Top five new positions opened include 95k Meta Platforms (Facebook) (META) 6/18 weekly 1030 calls, 42k Tesla (TSLA) Apr-24 177.5 calls, 40k V F Corp (VFC) Mar-25 10 puts, 30k Alphabet Class A (GOOGL) Apr-24 165 calls and 30k Tesla (TSLA) 6/18 weekly 100 calls.

Catch up on the weekend's top five stories with this list compiled by The Fly: 1. Salesforce (CRM) is in advanced talks to acquire Informatica (INFA) but the price being discussed is below Informatica's closing stock price of $38.48 as a result of the recent jump, Lauren Thomas, Laura Cooper and Dana Cimilluca of Wall Street Journal report, citing people familiar with the matter. 2. Apple (AAPL) denied violating a court order governing its App Store and urged a California federal judge to reject a request by "Fortnite" developer Epic Games to hold it in contempt, Reuters' Mike Scarcella reports. Apple made the arguments in a filing to U.S. District Judge Yvonne Gonzalez Rogers in Oakland, who presided over Epic's lawsuit in 2020 accusing Apple of violating antitrust law with its tight controls over how consumers download apps and pay for transactions within them. The Apple filing criticized what it called an attempt by Epic to make Apple's "tools and technologies available to developers for free." 3. Netflix (NFLX) is the forgotten tech giant - but its upcoming earnings report should help investors remember why they loved the stock in the first place, Paul R. La Monica writes in this week's edition of Barron's. The streaming-media leader was once part of the Nasdaq's FAANG club, an acronym traders used to describe Facebook parent Meta Platforms (META), Amazon.com (AMZN), Apple, Netflix, and Google owner Alphabet (GOOGL). But FAANG has since been replaced by the Magnificent Seven, a group that includes the four largest FAANGs, as well as Microsoft (MSFT), Nvidia (NVDA), and Tesla (TSLA)...and excludes Netflix. But with Netflix set to report its first-quarter earnings on April 18, investors shouldn't sleep on the stock, the author says. 4. A24's "Civil War" won this weekend's box office with a $25.7M debut, making it the biggest opening ever for A24. The dystopian action movie sports a B- CinemaScore, with the audience skewing heavily male - 73%. The debut is also the biggest for an R-rated movie this year. 5. Timken (TKR) saw a positive mention in this week's edition of Barron's.