Catch up on today's top five analyst downgrades with this list compiled by The Fly: 1. Express Scripts (ESRX) downgraded to Underperform from Market Perform at Wells Fargo with analyst Peter Costa saying the shares do not reflect the 20%-40% earnings risk related to re-pricing of or losing the Anthem (ANTM) contract. The analyst also sees risk of market share losses related to Express' pharmacy benefit manager model. Costa cut his price target range for the shares to $52-$56 from $79-$85. 2. AMC Entertainment (AMC) downgraded to Underperform from Neutral at Credit Suisse with analyst Omar Sheikh saying 2017 will be a transition year with investments likely depressing cash flow. Over the long term, the analyst believes premium video on demand could be disruptive to the business models of exhibitors. He cut his price target for AMC shares to $26 from $34. 3. American Water (AWK) downgraded to Hold from Buy at HSBC with analyst Verity Mitchell citing the recent rally in the shares and the belief that rising interest rates are likely to be less supportive of a regulated utility that yields only 2.2% for 2017. The analyst keeps a $79 price target for the shares. 4. Citrix (CTXS) downgraded to Neutral on valuation at BofA/Merrill with analyst Kash Rangan citing valuation, and raised his price target to $91 from $87. 5. Ventas (VTR) downgraded to Sell from Neutral at Goldman with analyst Andrew Rosivach saying rising interest rates will meaningfully affect the company's ability to produce external growth. The analyst cut his price target for the shares to $56 from $70. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.