Catch up on today's top five analyst downgrades with this list compiled by The Fly: 1. ImmunoGen (IMGN) downgraded to Underweight from Neutral at JPMorgan with analyst Jessica Fye saying the failure of Forward I is a "meaningful setback" for the mirvetuximab development program. 2. Vertex (VRTX) downgraded to Market Perform from Outperform at SVB Leerink with analyst Geoffrey Porges citing the slower ramp of the company's cystic fibrosis products in Europe, the already high expectations priced into the stock and the limited near-term opportunities and catalysts from the company's pipeline. 3. iRobot (IRBT) downgraded to Hold from Buy at Needham with analyst James Ricchiuti stating the market appears to be pricing in expectations of "meaningful upside" to the company's 2019 guidance after the run-up in its stock price this year. 4. Yum! Brands (YUM) downgraded to Neutral from Overweight at JPMorgan with analyst John Ivankoe saying the 9% year-to-date run in shares leaves little upside to estimates. 5. Boeing (BA) downgraded to Hold from Buy at Argus with analyst John Eade stating that he believes company management has not been particularly proactive in its response to two fatal crashes involving the 737 Max jet. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage,
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