Today's noteworthy downgrades include: Lantheus (LNTH) downgraded to Neutral from Outperform at Baird... MSCI (MSCI) downgraded to Neutral from Buy at Northcoast... PetroChina (PTR) downgraded to Neutral from Buy at BofA/Merrill... Regeneron (REGN) downgraded to Neutral from Buy at Chardan... Regis (RGS) downgraded to Neutral from Buy at Northcoast... Southern Copper (SCCO) downgraded to Neutral from Overweight at JPMorgan... Syngenta (SYT) downgraded to Neutral at UBS... United Technologies (UTX) downgraded to Equal Weight from Overweight at Barclays... Vermilion Energy (VET) downgraded to Neutral from Buy at BofA/Merrill... Yamana Gold (AUY) downgraded to Sector Perform from Outperform at Scotiabank.

Oppenheimer analyst Hartaj Singh raised the firm's price target on Regeneron to $1,175 from $1,125 and keeps an Outperform rating on the shares ahead of the Q1 earnings report on May 2. Oppenheimer believes the areas of focus will be the status and dynamics of the Eylea High Dose launch, questions around the impending Dupixent COPD PDUFA, the status of the two oncology approvals expected in 2024, updates on various pipeline projects in immunology and oncology, and comments on capital allocation and financial planning by the new CFO at the company.