Deutsche Bank analyst Gregg Gilbert raised his price target for Novocure to $44 after adjusting his model to reflect added patient-based models for GBM outside the U.S. and preliminary assumptions for the recent China collaboration. The analyst, however, keeps a Hold rating on the shares as he does not believe the risk/reward over the next 12 months is "sufficiently positive" to justify a Buy at current levels. Nonetheless, Gilbert continues to believe that "significant upside" is possible over few years if Phase 3 read-outs in larger tumor types are positive.

Novocure announced the results of the METIS phase 3 clinical trial in brain metastases from non-small cell lung cancer will be presented at the 2024 American Society of Clinical Oncology Annual Meeting in Chicago, to be held from May 31 to June 4. METIS was a randomized phase 3 clinical trial of stereotactic radiosurgery with or without Tumor Treating Fields therapy for patients with 1-10 brain metastases from NSCLC. In March, Novocure announced METIS met its primary endpoint, demonstrating a statistically significant improvement in time to intracranial progression for adult patients with Tumor Treating Fields therapy and supportive care compared to supportive care alone. "We are honored to present the results of the METIS clinical trial as a late-breaking abstract this year at ASCO, the largest global oncology conference," said Asaf Danziger, Novocure's CEO. "Patients with brain metastases from non-small cell lung cancer need more treatment options. The METIS trial demonstrated that TTFields Therapy delayed intracranial progression while preserving neurological function, which is critical for these underserved patients. We look forward to robust discussion around the positive results of the METIS clinical trial, as well as other TTFields therapy program updates at ASCO 2024."