Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Orion Engineered (OEC) initiated with a Neutral at Goldman Sachs. 2. National Grid (NGG) reinstated with an Equal Weight at Barclays. 3. SAGE Therapeutics (SAGE) initiated with a Buy at BofA/Merrill. 4. Quest Diagnostics (DGX) initiated with a Hold at Argus. 5. First Foundation (FFWM) initiated with a Neutral at Piper Jaffray. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.

These names in the biotech sector are seeing a substantial increase in search activity today, as determined by InvestingChannel. They include: Intra-Cellular Therapies... To see the rest of the story go to thefly.com. See Story Here

Oppenheimer analyst Jay Olson lowered the firm's price target on Sage Therapeutics to $17 from $25 and keeps a Perform rating on the shares. The firm notes Phase 2 PRECEDENT topline results showed no difference in efficacy for SAGE-718 vs. placebo in PD-MCI patients, and it suspects investors are now discounting nearly the entire value of SAGE-718 by assuming direct read-across to ongoing studies in HD and AD MCI that read-out later this year. However, while Oppenheimer agrees with the negative read-across, it thinks it's limited by several distinct factors for the HD and AD studies, including differences in disease states driving MCI, inclusion criteria, sample size, endpoints, and duration of treatment.

Get caught up quickly on the top news and calls moving stocks with these five Top Five lists. 1... To see the rest of the story go to thefly.com. See Story Here

Get caught up quickly on the top news and calls moving stocks with these five Top Five lists. 1... To see the rest of the story go to thefly.com. See Story Here

H.C. Wainwright analyst Douglas Tsao reiterates a Neutral rating on Sage Therapeutics after the company discontinued SAGE-718 in Parkinson's after the PRECEDENT study showed no benefit. The results are disappointing and, more importantly, raise concern about the upcoming top-line data readouts for SAGE-718 in Alzheimer's disease and Huntington's disease, the analyst tells investors in a research note. The firm recognizes the differences between the indications, but it also sees similarities. As such, SAGE-718's lack of treatment effect in Parkinson's patients "gives us additional pause heading into the next set of readouts," contends H.C. Wainwright.

BofA downgraded Sage Therapeutics to Underperform from Neutral with a price target of $14, down from $24.

Check out this morning's top movers from around Wall Street, compiled by The Fly.  HIGHER - Alcoa (AA)... To see the rest of the story go to thefly.com. See Story Here