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AZN

AstraZeneca

$33.00

0.14 (0.43%)

06:25
10/04/16
10/04
06:25
10/04/16
06:25

AstraZeneca says Brilinta did not meet primary endpoint in EUCLID trial

AstraZeneca announced top-line results from the EUCLID trial. Brilinta did not demonstrate a benefit over clopidogrel in a symptomatic peripheral artery disease patient population and therefore did not meet the primary endpoint of the trial.The EUCLID trial included 13,885 patients in 28 countries and is the largest cardiovascular outcomes trial to date conducted exclusively in symptomatic patients with PAD. It evaluated the treatment of Brilinta 90mg tablets twice daily versus clopidogrel 75mg once daily for the prevention of atherothrombotic events. The primary endpoint of the trial was the time to first occurrence of any such event. Based on preliminary analyses, safety data is consistent with the known safety profile of Brilinta. Sean Bohen, Executive Vice President, Global Medicines Development and Chief Medical Officer at AstraZeneca, said: "The proven benefits of Brilinta in acute coronary syndrome and post-myocardial infarction patients are established and remain unchanged. We are disappointed that the EUCLID trial results showed Brilinta did not demonstrate a benefit over clopidogrel in this specific symptomatic PAD population." Full results from the EUCLID trial are expected to be presented at the American Heart Association Scientific Sessions in New Orleans, Louisiana in November 2016.

  • 07

    Oct

  • 16

    Nov

AZN AstraZeneca
$33.00

0.14 (0.43%)

09/12/16
09/12/16
UPGRADE

On The Fly: Top five analyst upgrades
Catch up on today's top five analyst upgrades with this list compiled by The Fly: 1. Pandora (P) upgraded to Buy from Neutral at SunTrust with analyst Robert Peck saying he thinks that a new interactive offering by the company could raise its contribution profit by 4%-9% and that the Street's 2017 estimates for the company "seem conservative." The analyst added that he thinks it's "very possible" that Pandora will be acquired. 2. AstraZeneca (AZN) upgraded to Buy from Hold at Jefferies with analyst Jeffrey Holford saying the company's MYSTIC oncology study could drive 39% share upside if successful. 3. Apache (APA) and upgraded to Overweight from Neutral at Atlantic Equities and to Peer Perform from Underperform at Wolfe Research. 4. Philip Morris (PM) upgraded to Conviction Buy from Neutral at Goldman with analyst Judy Hong saying she is increasingly bullish on the prospects of Next Generation Products and expects them to contribute 5%-6% of earnings by 2020. 5. Wal-Mart (WMT) upgraded to Outperform from Market Perform at Cowen with analysts led by Oliver Chen saying price investments, integration of physical and digital, and the Jet acquisitions position the company to regain its dominance. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.
09/13/16
EXAN
09/13/16
DOWNGRADE
EXAN
Neutral
AstraZeneca downgraded to Neutral from Outperform at Exane BNP Paribas
09/23/16
PIPR
09/23/16
INITIATION
PIPR
Overweight
AstraZeneca initiated with an Overweight at Piper Jaffray
Piper Jaffray analyst Richard Purkiss started AstraZeneca with an Overweight rating and GBP 60 price target.
09/23/16
09/23/16
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Morgan Stanley analyst Brian Nowak initiated Activision Blizzard (ATVI) and Electronic Arts (EA), both with Overweight ratings. The analyst is bullish on the digital gaming shift away from "units sold" to a business model based on users, engagement, and digital monetization. He sees digital in-game offerings resulting in recurring and growth user bases, increased per-game engagement, and further monetization opportunities. 2. AstraZeneca (AZN) and GlaxoSmithKline (GSK) both initiated with Overweight ratings by Piper Jaffray analyst Richard Purkiss. 3. Achillion (ACHN) initiated with an Outperform by Wedbush analyst Heather Behanna, who set a $13 price target on the shares. 4. Sysco (SYY) initiated with an Underweight at Barclays and $48 price target by analyst Karen Short. 5. Five Below (FIVE), Dollar Tree (DLTR) and Dollar General (DG) all initiated with Equal Weight ratings by Barclays analyst Karen Short. This list is just a portion of The Fly's full analyst coverage. To see The Fly's full Street Research coverage, click here.

TODAY'S FREE FLY STORIES

INBK

First Internet Bancorp

$40.15

-0.35 (-0.86%)

16:46
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PGLC

Pershing Gold

$2.42

-0.01 (-0.41%)

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Breaking Syndicate news story on Pershing Gold »

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General news
Fed Balance Sheet Level data reported »

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Money Supply M2 Weekly Change data reported »

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BJRI

BJ's Restaurants

$37.90

-0.1 (-0.26%)

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Hot Stocks
Integrated Core Strategies reports 5.2% passive stake in BJ's Restaurants »

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VNO

Vornado

$71.34

0.04 (0.06%)

16:41
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Earnings
Vornado reports special items impacting Q4 financial results »

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NTCT

NetScout

$26.78

0.175 (0.66%)

16:38
01/18/18
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Hot Stocks
NetScout enters into amended credit agreement »

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  • 30

    Jan

NBLX

Noble Midstream

$55.58

-0.02 (-0.04%)

16:35
01/18/18
01/18
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Hot Stocks
Salient reports 6.23% passive stake in Noble Midstream »

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  • 22

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    Feb

HHS

Harte-Hanks

16:35
01/18/18
01/18
16:35
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16:35
Hot Stocks
Harte-Hanks COO/CTO Shirish Lal leaving the company »

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GWGH

GWG Holdings

$8.10

-0.2 (-2.41%)

16:35
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Hot Stocks
Breaking Hot Stocks news story on GWG Holdings »

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SPB

Spectrum Brands

$121.30

-3.86 (-3.08%)

16:32
01/18/18
01/18
16:32
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Hot Stocks
Spectrum Brands postpones 2018 annual shareholder meeting »

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  • 18

    Jan

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  • 08

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NTIP

Network-1 Technologies

$2.50

0.05 (2.04%)

, JNPR

Juniper

$27.66

-1.01 (-3.52%)

16:32
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Hot Stocks
Network-1 Technologies announces revised patent settlement with Juniper »

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NTIP

Network-1 Technologies

$2.50

0.05 (2.04%)

JNPR

Juniper

$27.66

-1.01 (-3.52%)

03/08/13
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  • 30

    Jan

ENFC

Entegra Financial

$28.90

-0.7 (-2.36%)

16:31
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01/18
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Earnings
Entegra Financial reports Q4 core EPS 54c, consensus 38c »

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  • 19

    Jan

16:30
01/18/18
01/18
16:30
01/18/18
16:30
Options
Preliminary option volume of 20.9M today »

Preliminary option volume…

NTES

NetEase

$322.19

-2.21 (-0.68%)

16:29
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01/18
16:29
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Recommendations
NetEase analyst commentary  »

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  • 07

    Feb

MS

Morgan Stanley

$55.84

0.49 (0.89%)

, AMZN

Amazon.com

$1,293.32

-1.68 (-0.13%)

16:25
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01/18
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General news
On The Fly: Top stock stories for Thursday »

Stocks opened little…

MS

Morgan Stanley

$55.84

0.49 (0.89%)

AMZN

Amazon.com

$1,293.32

-1.68 (-0.13%)

LGF.A

Lionsgate

$34.50

2.22 (6.88%)

LGF.B

Lionsgate

$32.84

2.46 (8.10%)

CBS

CBS

$60.00

1.1 (1.87%)

VIA

Viacom

$39.70

1.85 (4.89%)

VIAB

Viacom

$33.95

1.99 (6.23%)

BA

Boeing

$340.16

-10.85 (-3.09%)

ERJ

Embraer

$24.50

-0.19 (-0.77%)

GNC

GNC Holdings

$5.26

1.79 (51.59%)

PTC

PTC

$69.95

3.25 (4.87%)

AA

Alcoa

$53.00

-3.99 (-7.00%)

ENDP

Endo

$7.35

-0.34 (-4.42%)

03/08/13
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  • 18

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  • 01

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  • 08

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  • 08

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  • 15

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  • 18

    Mar

SRG

Seritage Growth Properties

$40.37

-0.4 (-0.98%)

16:25
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Hot Stocks
Seritage Growth Properties sees FY17 leasing activity 2.6M sqf, up 26% on year »

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MNST

Monster Beverage

$66.47

-0.6 (-0.89%)

16:25
01/18/18
01/18
16:25
01/18/18
16:25
Conference/Events
Monster Beverage to host investor meeting »

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  • 18

    Jan

MGM

MGM Resorts

$36.07

-0.47 (-1.29%)

, WYNN

Wynn Resorts

$175.48

1.89 (1.09%)

16:23
01/18/18
01/18
16:23
01/18/18
16:23
Initiation
MGM Resorts, Wynn Resorts, Eldorado Resorts, Penn National initiated  »

MGM Resorts initiated…

MGM

MGM Resorts

$36.07

-0.47 (-1.29%)

WYNN

Wynn Resorts

$175.48

1.89 (1.09%)

ERI

Eldorado Resorts

$31.60

-0.4 (-1.25%)

PENN

Penn National

$32.26

-0.49 (-1.50%)

03/08/13
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BANF

BancFirst

$55.20

0.95 (1.75%)

16:22
01/18/18
01/18
16:22
01/18/18
16:22
Hot Stocks
BancFirst to raise company minimum wage »

Executive Chairman David…

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MTOR

Meritor

$23.82

-0.3 (-1.24%)

16:22
01/18/18
01/18
16:22
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16:22
Hot Stocks
Meritor realigns segments and leadership positions »

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  • 31

    Jan

  • 13

    Feb

  • 14

    Feb

BANF

BancFirst

$55.20

0.95 (1.75%)

16:21
01/18/18
01/18
16:21
01/18/18
16:21
Earnings
BancFirst reports Q4 EPS 59c, consensus 69c »

Due to the signing of the…

03/08/13
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ATHN

athenahealth

$125.53

-0.65 (-0.52%)

16:20
01/18/18
01/18
16:20
01/18/18
16:20
Initiation
athenahealth initiated  »

athenahealth initiated…

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  • 02

    Feb

VIX

Volatility Index S&P 500 Options

16:20
01/18/18
01/18
16:20
01/18/18
16:20
Options
Closing CBOE SPX and VIX Index summary for January 18th »

The CBOE Volatility Index…

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AXP

American Express

$99.86

-0.9 (-0.89%)

16:19
01/18/18
01/18
16:19
01/18/18
16:19
Hot Stocks
Breaking Hot Stocks news story on American Express »

American Express down…

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  • 18

    Jan

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