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AMGN

Amgen

$167.24

-0.31 (-0.19%)

16:12
10/05/16
10/05
16:12
10/05/16
16:12

Amgen to present new data on IMLYGIC, Vectibix at ESMO

Amgen announced that new data on IMLYGIC in combination with an immune checkpoint inhibitor and results from retrospective analyses on Vectibix will be presented at the European Society for Medical Oncology 2016 Congress, Oct. 7-11, 2016, in Copenhagen. IMLYGIC presentations include interim results from a Phase 2 trial evaluating IMLYGIC in combination with ipilimumab versus ipilimumab alone in patients with unresected stage IIIB-IV melanoma. Vectibix abstracts include retrospective analyses of the first-line Phase 3 PRIME and PEAK studies, evaluating the association between tumor site of origin and treatment efficacy in patients with RAS wild-type metastatic colorectal cancer.

  • 07

    Oct

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    Oct

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    Nov

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    Nov

  • 19

    Jul

AMGN Amgen
$167.24

-0.31 (-0.19%)

09/01/16
09/01/16
NO CHANGE

Amgen's sBLA for Blincyto approved by FDA
Amgen's supplemental Biologics License Application for Blincyto has been approved by the FDA to include new data supporting the treatment of pediatric patients with Philadelphia chromosome-negative relapsed or refractory B-cell precursor acute lymphoblastic leukemia. This indication is approved under accelerated approval, and continued approval may be contingent upon verification of clinical benefit in subsequent trials. The approval is based on results from the Phase 1/2 '205, an open-label, multicenter, single-arm trial, which evaluated the efficacy and safety of BLINCYTO in pediatric patients with relapsed or refractory B-cell precursor ALL. Blincyto was granted breakthrough therapy, priority review and orphan drug designations by FDA, and is now approved in the U.S. for the treatment of Ph- relapsed or refractory B-cell precursor ALL. In November 2015, BLINCYTO was granted conditional marketing authorization in the European Union for the treatment of adults with Ph- relapsed or refractory B-cell precursor ALL.
09/27/16
GSCO
09/27/16
NO CHANGE
Target $206
GSCO
Conviction Buy
Goldman surprised by Amgen's Kyprolis outcome in first-line multiple myeloma
Last night, Amgen announced Phase 3 Kypolis CLARION study did not meet the primary endpoint in first-line multiple myeloma. Goldman analyst Terence Flynn was surprised by this outcome given the prior positive superiority data for Kyprolis versus Velcade in the Phase III ENDEAVOR trial. Flynn sees risk to his Kyprolis $1B sales estimate in a first-line setting, but awaits for additional details from the call and further information regarding another ongoing Phase III trial. He expects Amgen shares to be weak on the news but said the company has additional drivers beyond Kyprolis including Repatha for high cholesterol and Erenumab for migraine with additional data expected in 2H 2016 and Q1 2017. Flynn remains Conviction Buy rated on Amgen and maintains his $206 price target.
09/27/16
PIPR
09/27/16
NO CHANGE
PIPR
Overweight
Amgen's Kyprolis in good shape despite trial miss, says Piper Jaffray
Piper Jaffray analyst Joshua Schimmer says Amgen's Kyprolis is still likely to be viewed as a "potent backbone, with the right drugs" after a Phase 3 study in front-line myeloma failed to reach its primary endpoint. The analyst believes the impact of the failed trial on Kyprolis use will be limited and he reiterates an Overweight rating on Amgen.
09/29/16
PIPR
09/29/16
NO CHANGE
Target $10
PIPR
Overweight
Arrowhead price target raised to $10 from $8 at Piper Jaffray
Piper Jaffray analyst Edward Tenthoff raised his price target for Arrowhead Pharmaceuticals (ARWR) to $10 after the company licensed two preclinical cardiovascular RNAi drugs with Amgen (AMGN). Amgen is the "ideal partner" and Arrowhead's balance sheet is now "meaningfully" strengthened, Tenthoff tells investors in a research note. He reiterates an Overweight rating on Arrowhead.

TODAY'S FREE FLY STORIES

TCEHY

Tencent

$56.92

1.565 (2.83%)

12:07
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LEGO Group, Tencent form partnership in China »

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AXP

American Express

$101.32

0.35 (0.35%)

12:06
01/16/18
01/16
12:06
01/16/18
12:06
Hot Stocks
American Express reports December net write-off rate 2.0% vs. 1.9% last month »

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    Jan

BX

Blackstone

$35.81

0.42 (1.19%)

12:05
01/16/18
01/16
12:05
01/16/18
12:05
Options
Blackstone call volume above normal and directionally bullish »

Bullish option flow…

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  • 01

    Feb

ICBK

County Bancorp

$30.16

0.38 (1.28%)

, MTW

Manitowoc

$40.09

0.73 (1.85%)

12:04
01/16/18
01/16
12:04
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12:04
Hot Stocks
ICB to purchase Manitowoc Company headquarters »

Investors Community Bank,…

ICBK

County Bancorp

$30.16

0.38 (1.28%)

MTW

Manitowoc

$40.09

0.73 (1.85%)

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RHHBY

Roche

$31.78

0.405 (1.29%)

12:02
01/16/18
01/16
12:02
01/16/18
12:02
Hot Stocks
Roche launches CE-marked VENTANA MMR IHC Panel »

Roche announced the…

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NSRGY

Nestle

$85.10

0.58 (0.69%)

12:02
01/16/18
01/16
12:02
01/16/18
12:02
Hot Stocks
Nestle agrees to sell U.S. confectionery business to Ferrero »

Nestle announced that it…

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HES

Hess Corp.

$54.16

-0.38 (-0.70%)

12:00
01/16/18
01/16
12:00
01/16/18
12:00
Periodicals
Hess to cut hundreds of jobs as it battles activist shareholder, Reuters says »

Hess plans to lay off…

03/08/13
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  • 05

    Feb

CECE

CECO Environmental

$5.22

-0.07 (-1.32%)

12:00
01/16/18
01/16
12:00
01/16/18
12:00
Hot Stocks
CECO Environmental reports award of 'large contract' to energy business »

CECO Environmental…

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  • 16

    Jan

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INFO

IHS Markit

$47.85

0.39 (0.82%)

11:55
01/16/18
01/16
11:55
01/16/18
11:55
Conference/Events
IHS Markit management to meet with RBC Capital »

Group Luncheon Meeting…

03/08/13
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  • 16

    Jan

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    Jan

GSK

GlaxoSmithKline

$37.74

0.24 (0.64%)

11:54
01/16/18
01/16
11:54
01/16/18
11:54
Upgrade
GlaxoSmithKline rating change  »

GlaxoSmithKline upgraded…

03/08/13
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  • 07

    Feb

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GSK

GlaxoSmithKline

$37.76

0.2646 (0.71%)

11:51
01/16/18
01/16
11:51
01/16/18
11:51
Upgrade
GlaxoSmithKline rating change  »

GlaxoSmithKline upgraded…

03/08/13
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  • 07

    Feb

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    Mar

SPY

SPDR S&P 500 ETF Trust

$278.99

1.07 (0.39%)

, SPX

S&P 500

11:50
01/16/18
01/16
11:50
01/16/18
11:50
Periodicals
Steve Bannon subpoenaed before grand jury by Mueller, NY Time says »

Special counsel Robert…

SPY

SPDR S&P 500 ETF Trust

$278.99

1.07 (0.39%)

SPX

S&P 500

03/08/13
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PBR

Petrobras

$11.67

0.1978 (1.72%)

11:50
01/16/18
01/16
11:50
01/16/18
11:50
Options
Large spreads in Petrobras as shares reach 52-week highs »

Large spreads in…

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MRK

Merck

$62.38

3.72 (6.34%)

11:45
01/16/18
01/16
11:45
01/16/18
11:45
Options
Merck call volume above normal and directionally bullish »

Bullish option flow…

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  • 18

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11:45
01/16/18
01/16
11:45
01/16/18
11:45
General news
Treasury's $90 B bill auction were mixed, with the 3-month outperforming »

Treasury's $90 B…

TTMI

TTM Technologies

$17.39

0.59 (3.51%)

11:45
01/16/18
01/16
11:45
01/16/18
11:45
Conference/Events
TTM Technologies management to meet with SunTrust »

Group luncheon to be held…

03/08/13
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  • 16

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11:40
01/16/18
01/16
11:40
01/16/18
11:40
General news
U.S. VIX equity volatility is up nearly 10% »

U.S. VIX equity…

LPI

Laredo Petroleum

$11.09

0.015 (0.14%)

11:36
01/16/18
01/16
11:36
01/16/18
11:36
Initiation
Laredo Petroleum initiated  »

Laredo Petroleum…

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11:35
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General news
6-Month Bill Auction Total Amount data reported »

6-Month Bill Auction…

11:34
01/16/18
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11:34
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11:34
General news
3-Month Bill Auction Total Amount data reported »

3-Month Bill Auction…

EVRI

Everi Holdings

$7.85

-0.09 (-1.13%)

, SGMS

Scientific Games

11:31
01/16/18
01/16
11:31
01/16/18
11:31
Hot Stocks
Everi Holdings names Harper Ko EVP, Chief Legal Officer - General Counsel »

Everi Holdings (EVRI)…

EVRI

Everi Holdings

$7.85

-0.09 (-1.13%)

SGMS

Scientific Games

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GME

GameStop

$17.79

0.03 (0.17%)

11:30
01/16/18
01/16
11:30
01/16/18
11:30
Options
Put buyers in Gamestop as shares attempt to stabilize »

Put buyers in Gamestop as…

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XOG

Extraction Oil & Gas

$14.16

-0.13 (-0.91%)

11:28
01/16/18
01/16
11:28
01/16/18
11:28
Conference/Events
Extraction Oil & Gas management to meet with SunTrust »

Field trip to company…

03/08/13
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  • 16

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    Feb

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11:27
01/16/18
01/16
11:27
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11:27
Conference/Events
Cowen healthcare policy analyst holds an analyst/industry conference call »

Healthcare Policy Analyst…

11:25
01/16/18
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Conference/Events
Wolfe Research airlines analyst hosts a luncheon »

Airlines Analyst Keay…

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