Breaking News Instant updates and real-time market news.

BMY

Bristol-Myers

$55.43

0.38 (0.69%)

16:53
10/09/16
10/09
16:53
10/09/16
16:53

Bristol-Myers reports quality-of-life data from CheckMate-141 trial

Bristol-Myers Squibb announced new patient-reported quality-of-life data from an exploratory endpoint in the pivotal Phase 3 CheckMate -141 trial evaluating Opdivo in patients with recurrent or metastatic squamous cell carcinoma of the head and neck after platinum therapy compared to investigator's choice of therapy -- methotrexate, docetaxel or cetuximab. Outcome assessments showed Opdivo stabilized patients' symptoms and functioning, including physical, role and social functioning across three separate instruments. Both PD-L1 expressors and non-expressors treated with investigator's choice of therapy experienced statistically significant worsening of patient-reported outcomes from baseline to week 15 versus Opdivo. In addition, Opdivo more than doubled the time to deterioration for most functional domains measured and significantly delayed the time to worsening symptoms of fatigue, dyspnea and insomnia, compared to investigator's choice of therapy. Specifically, patient-reported outcomes were collected using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire, EORTC Head and Neck Cancer-Specific Module and the 3-level EQ-5D questionnaire. Both the EORTC QLQ-C30 and EORTC QLQ-H&N35 questionnaires showed there were significant differences in PROs between patients treated with Opdivo and those treated with investigator's choice of therapy at 15 weeks. In the EORTC QLQ-C30, while patients treated with Opdivo had stable PROs relative to baseline, those treated with investigator's choice of therapy had significant and clinically meaningful worsening of physical, role and social functioning, fatigue, dyspnea and appetite loss. Opdivo more than doubled the median time to deterioration for global health status, at 7.7 versus 3.0 months; physical functioning, at 7.8 versus 3.6 months; role functioning, at 8.6 versus 3.8 months; cognitive functioning, at 7.8 versus 3.3 months; and social functioning, at 7.7 versus 3.0 months compared with investigator's choice of therapy. In emotional functioning, Opdivo demonstrated a median time to deterioration of 6.7 months versus 4.7 months for investigator's choice of therapy. Opdivo also reduced the rate of clinically meaningful deterioration in fatigue, insomnia and dypsnea by 50%. While patients treated with Opdivo reported stable PROs relative to baseline, those treated with investigator's choice of therapy had significant worsening in pain as well as significant and clinically meaningful worsening in sensory problems and social contact problems. Compared with investigator's choice of therapy, Opdivo reduced the rate of clinically meaningful deterioration in pain by 74%, sensory problems by 62% and opening mouth problems by 51%. Patients treated with Opdivo experienced stable health status, as measured by the EQ-5D VAS, whereas those in the investigator's choice arm experienced worsening of health status, with a statistically significant difference at 15 weeks. Median time to deterioration of health status was nearly triple with 9.1 months for patients receiving Opdivo versus 3.3 months for those in the investigator's choice arm.

  • 09

    Oct

  • 27

    Oct

  • 31

    Oct

  • 06

    Nov

BMY Bristol-Myers
$55.43

0.38 (0.69%)

09/12/16
JEFF
09/12/16
NO CHANGE
Target $57
JEFF
Hold
Jefferies cuts Bristol-Myers price target, upgrades AstraZeneca
Jefferies analyst Jeffrey Holford lowered his price target for Bristol-Myers Squibb (BMY) to $57 from $69 saying the stock is positioned for a "rough mid term ride." The analyst sees a "difficult catalyst" set for Bristol shares with "numerous" upcoming competitor read-outs in non-small cell lung cancer. The market could see worse than expected data from Bristol's CM-026 and CM-568 studies as well as better than expected data from AstraZeneca's (AZN) MYSTIC study and Roche's (RHHBY) Chemo-IO studies in the first half of 2017, Holford tells investors in a research note. He keeps a Hold rating on Bristol and upgraded this morning AstraZeneca to Buy from Hold. Holford prefers Astra for its immunology exposure.
09/20/16
SBSH
09/20/16
NO CHANGE
Target $70
SBSH
Buy
Bristol-Myers price target lowered to $70 from $75 at Citi
In a research note titled "Brace Yourself. Attractive Valuation but No Near-Term Respite.," Citi analyst Andrew Baum lowered his price target for shares of Bristol-Myers Squibb to $70 from $75. The analyst lowered his earnings forecasts by up to 8% to reflect the "limited supportive data" in the non-small cell lung cancer indication. Baum keeps a Buy rating on the shares as he views the valuation as attractive. He points out, however, the near-term news-flow is likely to be negative.
09/27/16
PIPR
09/27/16
NO CHANGE
Target $62
PIPR
Neutral
Bristol-Myers price target lowered to $62 from $65 at Piper Jaffray
Piper Jaffray analyst Richard Purkiss lowered his price target for Bristol-Myers Squibb (BMY) to $62 saying he sees the company ceding Opdivo's early-mover advantage in lung cancer to competitors. The analyst expects to see details from Roche's (RHHBY) positive OAK trial of Tecentriq vs. docetaxel in non-small cell lung cancer at the upcoming ESMO meeting. Purkiss also expects to see details from Merck's (MRK) positive KEYNOTE-024 trial of Keytruda. The analyst lowered his post-2016 Opdivo forecasts and reiterates a Neutral rating on Bristol shares.
09/28/16
ROTH
09/28/16
NO CHANGE
Target $23
ROTH
Buy
Nektar price target raised to $23 from $19 at Roth Capital
Roth Capital analyst Michael Higgins raised his price target for Nektar (NKTR) to $23 from $19 after the company and Bristol-Myers (BMY) announced a clinical collaboration to evaluate the combination of the latter's anti-PD-1 antibody, Opdivo, with NKTR-214. The analyst reiterates a Buy rating on Nektar's shares.

TODAY'S FREE FLY STORIES

02:30
01/19/18
01/19
02:30
01/19/18
02:30
General news
FX Update: The dollar has traded softer on U.S. political concerns »

FX Update: The dollar…

01:50
01/19/18
01/19
01:50
01/19/18
01:50
General news
FX Action: USD-JPY has traded moderately softer »

FX Action: USD-JPY has…

COLD

Americold Realty Trust

20:35
01/18/18
01/18
20:35
01/18/18
20:35
Syndicate
Americold Realty Trust 45.3M share IPO priced at $16.00 »

The company sold 29M…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 19

    Jan

HTGM

HTG Molecular

$3.40

0.54 (18.88%)

20:29
01/18/18
01/18
20:29
01/18/18
20:29
Syndicate
HTG Molecular 12M share Secondary priced at $2.90 »

The deal size was…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 19

    Jan

NINE

Nine Energy Services

20:27
01/18/18
01/18
20:27
01/18/18
20:27
Syndicate
Nine Energy Services 7M share IPO priced at $23.00 »

The deal priced at the…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 19

    Jan

SLB

Schlumberger

$76.37

-0.84 (-1.09%)

, STI

SunTrust

$67.94

-0.41 (-0.60%)

20:25
01/18/18
01/18
20:25
01/18/18
20:25
Earnings
Notable companies reporting before tomorrow's open »

Notable companies…

SLB

Schlumberger

$76.37

-0.84 (-1.09%)

STI

SunTrust

$67.94

-0.41 (-0.60%)

SYF

Synchrony

$37.30

-0.76 (-2.00%)

CFG

Citizens Financial

$45.76

-0.08 (-0.17%)

RF

Regions Financial

$18.15

-0.21 (-1.14%)

KSU

Kansas City Southern

$111.50

0.69 (0.62%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 19

    Jan

  • 19

    Jan

  • 19

    Jan

  • 19

    Jan

  • 19

    Jan

  • 19

    Jan

  • 20

    Apr

  • 20

    Jul

  • 19

    Oct

URGN

UroGen Pharma

$42.46

-0.8 (-1.85%)

19:12
01/18/18
01/18
19:12
01/18/18
19:12
Syndicate
UroGen Pharma 1.463M share Secondary priced at $41.00 »

The deal size was…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 19

    Jan

ADT

ADT Inc.

19:10
01/18/18
01/18
19:10
01/18/18
19:10
Syndicate
ADT Inc. 105M share IPO priced at $17.00-19.00 »

The deal priced below the…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 19

    Jan

SPX

S&P 500

, SPY

SPDR S&P 500 ETF Trust

$279.14

-0.47 (-0.17%)

18:47
01/18/18
01/18
18:47
01/18/18
18:47
Periodicals
House Freedom Caucus to support bill preventing government shutdown, AP says 

Reference Link

SPX

S&P 500

SPY

SPDR S&P 500 ETF Trust

$279.14

-0.47 (-0.17%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

BK

BNY Mellon

$55.35

-2.54 (-4.39%)

18:39
01/18/18
01/18
18:39
01/18/18
18:39
Periodicals
BNY Mellon to boost wages for 1,000 workers after tax reform, WSJ says »

Bank of New York Mellon…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 18

    Jan

  • 08

    Mar

TRNC

tronc

$19.23

0.22 (1.16%)

18:28
01/18/18
01/18
18:28
01/18/18
18:28
Periodicals
tronc to investigate LA Times' CEO Ross Levinsohn, Financial Times reports »

tronc has opened an…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 18

    Jan

IBM

IBM

$169.12

0.47 (0.28%)

18:19
01/18/18
01/18
18:19
01/18/18
18:19
Hot Stocks
IBM's Schroeter says mainframe isn't going away »

IBM senior VP of Global…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 18

    Jan

ATR

AptarGroup

$87.24

0.4 (0.46%)

18:16
01/18/18
01/18
18:16
01/18/18
18:16
Hot Stocks
AptarGroup chairman King Harris to retire in May »

AptarGroup chairman of…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 13

    Feb

  • 27

    Apr

  • 02

    May

  • 27

    Jul

  • 26

    Oct

FULT

Fulton Financial

$18.30

-0.25 (-1.35%)

18:12
01/18/18
01/18
18:12
01/18/18
18:12
Hot Stocks
Fulton Financial to raise its minimum wage to $12 per hour »

Fulton Financial…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 23

    Jan

SNAP

Snap

$14.01

0.49 (3.62%)

18:03
01/18/18
01/18
18:03
01/18/18
18:03
Periodicals
Snap fires roughly two dozen employees, Cheddar reports »

Snap Inc. has laid off…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 18

    Jan

  • 23

    Jan

  • 06

    Feb

  • 07

    Feb

PAVM

PAVmed

$2.54

-0.02 (-0.78%)

17:57
01/18/18
01/18
17:57
01/18/18
17:57
Syndicate
PAVmed files to sell common stock, no amount given »

Dawson James Securities…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

PODD

Insulet

$72.89

-0.02 (-0.03%)

, DXCM

Dexcom

$56.28

-0.04 (-0.07%)

17:51
01/18/18
01/18
17:51
01/18/18
17:51
Recommendations
Insulet, Dexcom, TNDM, Medtronic analyst commentary at Piper Jaffray »

Insulet is a favored…

PODD

Insulet

$72.89

-0.02 (-0.03%)

DXCM

Dexcom

$56.28

-0.04 (-0.07%)

TNDM

TNDM

MDT

Medtronic

$87.26

1.15 (1.34%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 26

    Feb

  • 27

    Feb

  • 01

    Mar

17:50
01/18/18
01/18
17:50
01/18/18
17:50
General news
Breaking General news story  »

Cleveland Federal Reserve…

IBM

IBM

$169.12

0.47 (0.28%)

17:39
01/18/18
01/18
17:39
01/18/18
17:39
Earnings
Breaking Earnings news story on IBM »

IBM sees FY18 adjusted…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 18

    Jan

TTD

Trade Desk

$48.36

-1.12 (-2.26%)

17:38
01/18/18
01/18
17:38
01/18/18
17:38
Initiation
Trade Desk initiated at Stifel »

Trade Desk initiated with…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

TWTR

Twitter

$24.04

-0.52 (-2.12%)

, FB

Facebook

$179.80

2.2 (1.24%)

17:37
01/18/18
01/18
17:37
01/18/18
17:37
Hot Stocks
Snap user metrics being put into question by Mashable, Muddy Waters »

After the close, Mashable…

TWTR

Twitter

$24.04

-0.52 (-2.12%)

FB

Facebook

$179.80

2.2 (1.24%)

SNAP

Snap

$14.01

0.49 (3.62%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 18

    Jan

  • 18

    Jan

  • 23

    Jan

  • 31

    Jan

  • 06

    Feb

  • 07

    Feb

  • 08

    Feb

  • 28

    Feb

TWTR

Twitter

$24.04

-0.52 (-2.12%)

17:37
01/18/18
01/18
17:37
01/18/18
17:37
Recommendations
Twitter analyst commentary at Stifel »

Twitter coverage…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 18

    Jan

  • 23

    Jan

  • 07

    Feb

  • 08

    Feb

  • 28

    Feb

IBM

IBM

$169.12

0.47 (0.28%)

17:36
01/18/18
01/18
17:36
01/18/18
17:36
Hot Stocks
Breaking Hot Stocks news story on IBM »

IBM sees FY18 free cash…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 18

    Jan

IBM

IBM

$169.12

0.47 (0.28%)

17:36
01/18/18
01/18
17:36
01/18/18
17:36
Earnings
IBM sees Q1 EPS 17%-18% of $13.80 FY expectation, consensus $2.28 »

Says has momentum in…

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 18

    Jan

ZG

Zillow

$43.86

-0.49 (-1.10%)

, Z

Zillow

$43.97

-0.57 (-1.28%)

17:33
01/18/18
01/18
17:33
01/18/18
17:33
Downgrade
Zillow, Zillow rating change at Stifel »

Zillow resumed with a…

ZG

Zillow

$43.86

-0.49 (-1.10%)

Z

Zillow

$43.97

-0.57 (-1.28%)

03/08/13
Wedge Partners
03/08/13
Credit Suisse
03/06/13
Citigroup
03/06/13
Barclays

See Street Research during your Free Trial

  • 26

    Feb

Get Full Fly Access

Breaking market intelligence sent straight to you
Our team of experts analyze every news story and filter out the noise to deliver real-time market moving news.
Up-to-date information on important industry events
Get real-time updates on events that are moving the market—from conferences and calls to syndicate announcements.
News focused on the companies in your portfolio
Create up to 12 portfolios with 150 stocks each, and see how active they are in market news.