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JUNO

Juno Therapeutics

$29.88

-1.56 (-4.96%)

08:02
11/23/16
11/23
08:02
11/23/16
08:02

Juno places Phase II ROCKET trial on hold after patient death

Juno Therapeutics announced that it has voluntarily placed on hold the Phase II clinical trial of JCAR015 in adult patients with relapsed or refractory B cell acute lymphoblastic leukemia, known as the "ROCKET" trial. The clinical hold was initiated after two patients suffered cerebral edema earlier this week. One patient died and as of last night the other is not expected to recover. Juno said it has notified the Food & Drug Administration of the voluntary hold and is working with the agency and the Data and Safety Monitoring Board to determine next steps. The company is assessing data from the cases and the trial and is evaluating its options regarding the JCAR015 program. Juno's trials and plans for its other CD19-directed CAR T cell product candidates, including JCAR017, are not affected.

  • 03

    Dec

  • 03

    Dec

JUNO Juno Therapeutics
$29.88

-1.56 (-4.96%)

09/27/16
LEER
09/27/16
NO CHANGE
LEER
Outperform
Kite's ZUMA-1 interim data incrementally positive for Juno, says Leerink
Leerink analyst Michael Schmidt says Kite Pharma's (KITE) top-line interim results from its pivotal ZUMA-1 trial of anti-CD19 CAR-T product KTE-C19 in patients with chemorefractory diffuse large B-cell lymphoma, or DLBCL, are incrementally positive for Juno Therapeutics (JUNO). While Juno is roughly one year behind Kite in DLBCL, the analyst believes its JCAR017 holds the promise to have a compelling safety/efficacy profile in lymphoma and Acute Lymphoblastic Leukemia. He reiterates an Outperform rating on Juno's shares.
11/03/16
BTIG
11/03/16
UPGRADE
BTIG
Neutral
Juno Therapeutics upgraded to Neutral from Sell at BTIG
11/04/16
BTIG
11/04/16
UPGRADE
BTIG
Neutral
Juno Therapeutics upgraded to Neutral from Sell at BTIG
BTIG analyst Dane Leone upgraded Juno Therapeutics (JUNO) to Neutral from Sell citing valuation following the ASH abstract release showed similar response rates for JCAR017 versus Kite's (KITE) KTE-C19 in the treatment of patients with Diffuse Large B-Cell Lymphoma.
11/10/16
RHCO
11/10/16
NO CHANGE
RHCO
Juno Therapeutics drug could deliver best in class data, says SunTrust
SunTrust analyst Peter Lawson says that Juno's non-Hodgkin lymphoma,treatment, JCAR017, could deliver best in class data at ASH. The analyst reiterates a $48 price target and a Buy rating on the shares.

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AAPL

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TM

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CBOE

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GWRE

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AAPL

Apple

$179.10

2.91 (1.65%)

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  • 01

    Feb

OBE

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SN

Sanchez Energy

$5.81

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  • 15

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SN

Sanchez Energy

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  • 15

    May

NTDOY

Nintendo

$51.53

1.55 (3.10%)

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  • 17

    Jan

PTC

PTC

$66.70

1.41 (2.16%)

, ESIO

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SLM

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ARWR

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PRTK

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Innovative Industrial Properties

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ECC

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AGIO

Agios Pharmaceuticals

$70.33

1.53 (2.22%)

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  • 19

    Jan

BTU

Peabody Energy

$40.00

0.42 (1.06%)

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  • 07

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MLNX

Mellanox

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  • 18

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APHB

AmpliPhi

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JNJ

Johnson & Johnson

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  • 23

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EVEP

EV Energy

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HBM

Hudbay Minerals

$10.05

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SFE

Safeguard Scientifics

$10.85

-0.15 (-1.36%)

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MSI

Motorola Solutions

$97.28

1.42 (1.48%)

, SSTI

ShotSpotter

$16.10

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MSI

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  • 20

    Feb

ERIE

Erie Indemnity

$117.23

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AAPL

Apple

$179.10

2.91 (1.65%)

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  • 01

    Feb

SLM

Sallie Mae

$11.49

0.02 (0.17%)

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Sallie Mae reports Q4 core EPS 19c, consensus 19c »

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  • 18

    Jan

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General news
Treasury TIC flows: foreign accounts bought $33.8 B in total U.S. assets »

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VZ

Verizon

$51.72

0.06 (0.12%)

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