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LXRX

Lexicon

$15.23

-1.1 (-6.74%)

06:13
12/22/16
12/22
06:13
12/22/16
06:13

Citi disagrees with market view on Lexicon Pharmaceuticals

After shares of Lexicon Pharmaceuticals fell 7% yesterday following data from the second Phase 3 testing sotagliflozin in Type 1 diabetes, Citi analyst Yigal Nochomovitz says he disagrees with the market view. Investors are "getting too bogged" down on the safety question, the analyst tells investors in a research note. The data "unambiguously solve a major clinical challenge" in Type 1, which is getting A1c lower without the expense of glycemic excursions and thus more hypos, Nochomovitz writes. He keeps a Buy rating on Lexicon with a $24 price target.

  • 19

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    Feb

LXRX Lexicon
$15.23

-1.1 (-6.74%)

08/02/16
SBSH
08/02/16
INITIATION
Target $21
SBSH
Buy
Lexicon initiated with a Buy at Citi
Citi analyst Yigal Nochomovitz started Lexicon Pharmaceuticals with a Buy rating and $21 price target. The analyst expects "timely approval and launch" of the company's lead drug telotristat etiprate, an add-on to standard of care to treat severe diarrhea in carcinoid syndrome patients. He believes this should provide near-term support for the stock.
09/12/16
SBSH
09/12/16
NO CHANGE
Target $25
SBSH
Buy
Lexicon price target raised to $25 from $21 at Citi
Citi analyst Yigal Nochomovitz raised his price target for Lexicon Pharmaceuticals to $25 saying sotagliflozin showed "strong efficacy" in its first Phase 3 trial in Type 1 diabetes mellitus. The analyst believes concerns over Sotagliflozin safety should be lifted on these data. He reiterates a Buy rating on Lexicon.
10/07/16
HCWC
10/07/16
INITIATION
Target $26
HCWC
Buy
Lexicon initiated with a Buy at H.C. Wainwright
H.C. Wainwright analyst Shaunak Deepak started Lexicon Pharmaceuticals with a Buy rating and $26 price target.
12/21/16
12/21/16
NO CHANGE

Lexicon's sotagliflozin meets primary endpoint in Phase 3 trial for diabetes
Lexicon Pharmaceuticals' pivotal inTandem2 Phase 3 clinical trial of sotagliflozin met its primary endpoint, showing a statistically significant reduction in A1C at 24 weeks in patients with type 1 diabetes on optimized insulin therapy. Top-line results from the Phase 3 study showed that patients treated with sotagliflozin had mean A1C reductions from baseline of 0.39% on 200mg once daily sotagliflozin dose and 0.37% on 400mg once daily sotagliflozin dose as compared to a reduction of 0.03% on placebo after 24 weeks of treatment, meeting the study's primary endpoint. This statistically significant and clinically meaningful improvement in A1C for both doses of sotagliflozin was achieved with a favorable overall safety profile in the study, including rates of severe hypoglycemia similar to placebo and low overall rates of diabetic ketoacidosis.

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