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REGN

Regeneron

$365.06

-5.96 (-1.61%)

14:02
12/22/16
12/22
14:02
12/22/16
14:02

Science publishes paper on Geisinger, Regeneron DiscovEHR collaboration

Geisinger Health System and Regeneron announced that Science has published a paper describing how the DiscovEHR collaboration between Geisinger and the Regeneron Genetics Center is using the combination of large-scale sequencing and de-identified electronic health records for genomic medicine implementation and precision medicine applications in genomics-guided therapeutic discovery. The publication describes exome sequencing and analyses of the first 50,000 adult participants in the DiscovEHR study, one of the first and largest efforts of its kind. Genomic data from these patients, all members of the Geisinger MyCode Community Health Initiative, have been linked to corresponding de-identified electronic health records, enabling the discovery of clinical associations supporting new and existing therapeutic targets, including genes encoding drug targets for lipid lowering. In the DiscovEHR study, approximately 3.5% of individuals were found to have known or predicted deleterious genetic variants in one of 76 clinically actionable genes. While the data are completely de-identified to Regeneron, clinicians at Geisinger have begun returning this information to eligible patients as part of their clinical care, with some 200 patients already informed they carry one or more disease-causing genetic mutations with consequences that can be treated. These mutations are mainly related to cancer risk and cardiovascular illness. "This is an important step forward for precision medicine," said David J. Carey, Ph.D., professor and chair of molecular and functional genomics at Geisinger and co-author of the papers. "In addition to contributing to longer-term research that leads to new treatments, Geisinger aims to be on the forefront of integrating genetic data into patient care today. Through this collaboration, individuals participating in the Geisinger MyCode Community Health Initiative may benefit in the near-term by receiving information about their personal health," he said.

  • 29

    Mar

REGN Regeneron
$365.06

-5.96 (-1.61%)

12/20/16
FBCO
12/20/16
UPGRADE
FBCO
Outperform
Regeneron upgraded to Outperform from Neutral at Credit Suisse
12/20/16
12/20/16
UPGRADE

Outperform
Regeneron upgraded ahead of Dupixent launch, PCSK9 outcomes at Credit Suisse
As previously reported, Credit Suisse upgraded Regeneron (REGN) to Outperform from Neutral and raised its price target to $485 from $481. Analyst Alethia Young shares have pulled back 30% since the beginning of 2016 and things the upcoming Dupixent launch in April and a PCSK9 outcomes read-through from Amgen (AMGN) in Q1 are catalysts. He estimates 2025 adjusted Dupixent sales in atopic dermatitis of $2.3B.
12/20/16
BMOC
12/20/16
INITIATION
BMOC
Market Perform
Regeneron initiated at BMO Capital
As noted earlier, BMO Capital started coverage of Regeneron with a Market Perform rating and a $419 price target. Analyst Matthew Luchini says he expects the growth of the company's franchise treatment, Eylea, to slow, while the Praluent litigation and Eylea Part B regulatory risk will continue to be overhangs on the stock. He believes that high expectations for the company's pipeline drugs Dupixent and sarilumab are already reflected in the shares. Target $419.
12/20/16
12/20/16
INITIATION

On The Fly: Top five analyst initiations
Catch up on today's top five analyst initiations with this list compiled by The Fly: 1. Square (SQ) initiated with a Buy at Nomura and with a Buy at Guggenheim. 2. Salesforce (CRM) initiated with a Buy at Drexel Hamilton. 3. Regeneron (REGN) initiated at BMO Capital. 4. Zoetis (ZTS) initiated with a Buy at Deutsche Bank. 5. trivago (TRVG) initiated with a Neutral at Susquehanna. This list is just a portion of The Fly's analyst coverage. To see The Fly's full Street Research coverage, click here.

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AFL

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  • 01

    Dec

GBL

GAMCO Investors

, WTS

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$72.65

0.15 (0.21%)

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$72.65

0.15 (0.21%)

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  • 04

    Dec

CC

Chemours

$53.31

0.45 (0.85%)

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  • 01

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AIMT

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  • 28

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CMCM

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GM

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