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AMGN

Amgen

$178.24

1.71 (0.97%)

17:20
03/01/17
03/01
17:20
03/01/17
17:20

Amgen's Blincyto shows improved survival in leukemia patients in Phase 3 trial

Amgen announced the New England Journal of Medicine published results from the Phase 3 TOWER study evaluating the efficacy of Blincyto versus standard of care chemotherapy in high-risk adult patients with Philadelphia chromosome-negative relapsed or refractory B-cell precursor acute lymphoblastic leukemia, one of the most aggressive B-cell malignancies. Results showed median overall survival was 7.7 months for Blincyto versus four months for SOC. The TOWER study is the confirmatory study for the Phase 2 trial that supported the FDA's accelerated approval designation for Blincyto in 2014. The survival benefit for Blincyto was independent of allogeneic stem cell transplant. Improvement in OS was generally consistent regardless of age, prior salvage therapy or prior alloSCT. Remission rates were also higher for Blincyto, 34% of complete remission, versus 16% in the SOC group. Among patients with complete remission or complete remission with partial or incomplete hematologic recovery, 76% in the Blincyto group versus 48% in the SOC group achieved minimal residual disease negative status. Safety results among subjects who received Blincyto were comparable to those seen in the Phase 2 studies in adult patients with Ph- relapsed or refractory B-cell precursor ALL.

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AMGN Amgen
$178.24

1.71 (0.97%)

02/13/17
BMOC
02/13/17
NO CHANGE
BMOC
Data bodes well for Amgen drug, says BMO Capital
BMO Capital analyst M. Ian Somaiya says that studies continue to indicate that reducing LDL-C levels continuously lower the risk of adverse cardiovascular events. As a result, the analyst is more confident that Amgen's Repatha drug can demonstrate a 20% improvement in cardiovascular outcomes. After conducting checks, he believes that such an outcome would enable the drug to meet his estimates which are 30%-50% above those of the Street. He raised his price target on Amgen to $212 from $202 and keeps an Outperform rating on the stock.
02/16/17
GSCO
02/16/17
DOWNGRADE
Target $417
GSCO
Neutral
Regeneron downgraded to Neutral from Buy at Goldman
Goldman Sachs analyst Terence Flynn downgraded Regeneron Pharmaceuticals (REGN) to Neutral from Buy citing valuation with the stock within 9% of his unchanged $417 price target. The analyst sees less upside potential relative to Regeneron's large-cap peers Amgen (AMGN) and Alexion (ALXN). Flynn adds that his revenue estimates for Regeneron's 2018-2020 are no longer above consensus following the PCSK9 litigation and recent Eylea guidance. The stock closed yesterday up $7.47 to $384.00.
02/22/17
OPCO
02/22/17
NO CHANGE
Target $189
OPCO
Outperform
Amgen price target raised to $189 from $175 at Oppenheimer
Oppenheimer analyst Leah Rush Cann raised her price target for Amgen to $189 from $175 after the company recently reported label expansion filings and FDA approvals. The analyst reiterates an Outperform rating on the shares.
02/23/17
LEER
02/23/17
NO CHANGE
LEER
AbbVie has the best near/mid-term outlook, says Leerink
Comparing AbbVie (ABBV), Amgen (AMGN) and Gilead (GILD) by assessing the earnings quality, earnings momentum, margin trajectory, and dividend and cash flow valuation metrics, Leerink analyst Geoffrey Porges says his analysis suggests that AbbVie offers "more attractive fundamentals" based on earnings momentum and dividend yield, and is also the only company of the three that is likely to show sustained improvements in operating margin and cash flow over the next four years. The analyst finds that AbbVie has the best near-to-mid-term outlook at a relatively discounted valuation compared to these similarly sized, value biopharma peers.

TODAY'S FREE FLY STORIES

CRVS

Corvus Pharmaceuticals

$13.00

1.13 (9.52%)

20:37
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PTLA

Portola Pharmaceuticals

$56.28

0.33 (0.59%)

20:35
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20:35
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TEVA

Teva

$16.49

-0.52 (-3.06%)

20:35
08/23/17
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20:35
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Teva rating change  »

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LOW

Lowe's

$73.01

-2.81 (-3.71%)

20:33
08/23/17
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20:33
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Lowe's rating change  »

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HRL

Hormel Foods

$33.92

-0.46 (-1.34%)

, DLTR

Dollar Tree

$74.32

-0.63 (-0.84%)

20:25
08/23/17
08/23
20:25
08/23/17
20:25
Earnings
Notable companies reporting before tomorrow's open »

Notable companies…

HRL

Hormel Foods

$33.92

-0.46 (-1.34%)

DLTR

Dollar Tree

$74.32

-0.63 (-0.84%)

SJM

J.M. Smucker

$118.85

-1.01 (-0.84%)

TIF

Tiffany

$88.72

0.22 (0.25%)

TTC

Toro Company

$69.02

-1.76 (-2.49%)

SPLS

Staples

$10.18

-0.02 (-0.20%)

BURL

Burlington Stores

$84.95

-1.43 (-1.66%)

MIK

Michaels

$19.61

0.02 (0.10%)

SIG

Signet Jewelers

$51.89

-0.26 (-0.50%)

ANF

Abercrombie & Fitch

$9.61

0.46 (5.03%)

03/08/13
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HSY

Hershey

$107.44

0.34 (0.32%)

19:16
08/23/17
08/23
19:16
08/23/17
19:16
Hot Stocks
Hershey Company to acquire 1.5M common shares from Hershey Trust »

The Hershey Company…

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MSADY

MS&AD Insurance

$17.08

-0.085 (-0.50%)

19:07
08/23/17
08/23
19:07
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19:07
Hot Stocks
MS&AD Insurance to acquire First Capital Insurance in $1.6B deal »

Fairfax Financial…

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AMGN

Amgen

$169.00

-1.07 (-0.63%)

18:46
08/23/17
08/23
18:46
08/23/17
18:46
Hot Stocks
Amgen: Lancet Oncology publishes survival analysis from KYPROLIS Phase 3 trial »

Amgen announced that…

03/08/13
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GE

General Electric

$24.39

-0.21 (-0.85%)

, ABB

ABB

$23.13

-0.01 (-0.04%)

18:39
08/23/17
08/23
18:39
08/23/17
18:39
Periodicals
GE resumes talks with ABB over industrial solutions deal, Reuters reports »

General Electric (GE) has…

GE

General Electric

$24.39

-0.21 (-0.85%)

ABB

ABB

$23.13

-0.01 (-0.04%)

03/08/13
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03/06/13
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LZB

La-Z-Boy

$24.95

-6.3 (-20.16%)

, AMZN

Amazon.com

$958.00

-8.9 (-0.92%)

18:17
08/23/17
08/23
18:17
08/23/17
18:17
Periodicals
La-Z-Boy in talks with Amazon over youth shopper outreach, MarketWatch reports »

La-Z-Boy (LZB) is in…

LZB

La-Z-Boy

$24.95

-6.3 (-20.16%)

AMZN

Amazon.com

$958.00

-8.9 (-0.92%)

03/08/13
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VLKAY

Volkswagen

$30.67

0.19 (0.62%)

18:14
08/23/17
08/23
18:14
08/23/17
18:14
Periodicals
VW to launch two-tone compact SUV, Bloomberg says »

Volkswagen plans to…

03/08/13
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F

Ford

$10.71

0.06 (0.56%)

18:01
08/23/17
08/23
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18:01
Hot Stocks
Ford names Jason Luo as chairman, CEO of Ford China »

Ford announced a new…

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BA

Boeing

$238.09

-1.66 (-0.69%)

, LMT

Lockheed Martin

$302.84

-1.96 (-0.64%)

17:47
08/23/17
08/23
17:47
08/23/17
17:47
Periodicals
Boeing 'disappointed' company not chosen for cruise missile deal, Bloomberg says »

Lockheed (LMT), Raytheon…

BA

Boeing

$238.09

-1.66 (-0.69%)

LMT

Lockheed Martin

$302.84

-1.96 (-0.64%)

RTN

Raytheon

$178.19

-1.03 (-0.57%)

03/08/13
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  • 23

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HBM

Hudbay Minerals

$8.50

0.2 (2.41%)

17:44
08/23/17
08/23
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17:44
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Hudbay Minerals acquires 10.76M common shares of Mason Resources »

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HPQ

HP Inc.

$18.86

-0.16 (-0.84%)

17:32
08/23/17
08/23
17:32
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17:32
Hot Stocks
Breaking Hot Stocks news story on HP Inc. »

HP Inc. sees Q4 PC…

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GES

Guess

$12.48

0.11 (0.89%)

, TLYS

Tilly's

$9.60

0.88 (10.09%)

17:29
08/23/17
08/23
17:29
08/23/17
17:29
Hot Stocks
On The Fly: After Hours Movers »

UP AFTER EARNINGS: Guess…

GES

Guess

$12.48

0.11 (0.89%)

TLYS

Tilly's

$9.60

0.88 (10.09%)

WSM

Williams-Sonoma

$43.40

0.55 (1.28%)

PVH

PVH Corp.

$120.04

-0.28 (-0.23%)

YUME

YuMe

$5.15

0.09 (1.78%)

HPQ

HP Inc.

$18.86

-0.16 (-0.84%)

HEI

Heico

$81.11

-0.95 (-1.16%)

GBT

Global Blood Therapeutics

03/08/13
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MATX

Matson

$24.02

0.24 (1.01%)

17:28
08/23/17
08/23
17:28
08/23/17
17:28
Hot Stocks
Matson upgrading its Honolulu terminal »

Matson announced that a…

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TCMD

Tactile Systems

$33.90

0.78 (2.36%)

17:24
08/23/17
08/23
17:24
08/23/17
17:24
Syndicate
Breaking Syndicate news story on Tactile Systems »

Tactile Systems files to…

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TCMD

Tactile Systems

$33.90

0.78 (2.36%)

17:23
08/23/17
08/23
17:23
08/23/17
17:23
Syndicate
Breaking Syndicate news story on Tactile Systems »

Tactile Systems files…

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CIVI

Civitas Solutions

$18.30

-0.1 (-0.54%)

17:21
08/23/17
08/23
17:21
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17:21
Recommendations
Civitas Solutions analyst commentary  »

Civitas announces…

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LLL

L3 Technologies

$179.28

-1.39 (-0.77%)

17:20
08/23/17
08/23
17:20
08/23/17
17:20
Hot Stocks
L3 Technologies awarded $172.9M government contract modification »

L-3 Communications Vertex…

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BA

Boeing

$238.08

-1.67 (-0.70%)

17:19
08/23/17
08/23
17:19
08/23/17
17:19
Hot Stocks
Boeing awarded $222.5M government contract modification »

The Boeing…

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RTN

Raytheon

$178.19

-1.03 (-0.57%)

17:18
08/23/17
08/23
17:18
08/23/17
17:18
Hot Stocks
Raytheon awarded approximately $900M government contract »

Raytheon Co., Tucson,…

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LMT

Lockheed Martin

$302.84

-1.96 (-0.64%)

17:17
08/23/17
08/23
17:17
08/23/17
17:17
Hot Stocks
Lockheed Martin awarded approximately $900M government contract »

Lockheed Martin Corp.,…

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  • 23

    Aug

HPQ

HP Inc.

$18.86

-0.16 (-0.84%)

, SSNLF

Samsung

$2,020.00

-10 (-0.49%)

17:11
08/23/17
08/23
17:11
08/23/17
17:11
Hot Stocks
HP Inc. sees Samsung deal closing in Q4 »

HP Inc. (HPQ) said it saw…

HPQ

HP Inc.

$18.86

-0.16 (-0.84%)

SSNLF

Samsung

$2,020.00

-10 (-0.49%)

03/08/13
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