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AMGN

Amgen

$178.24

1.71 (0.97%)

17:20
03/01/17
03/01
17:20
03/01/17
17:20

Amgen's Blincyto shows improved survival in leukemia patients in Phase 3 trial

Amgen announced the New England Journal of Medicine published results from the Phase 3 TOWER study evaluating the efficacy of Blincyto versus standard of care chemotherapy in high-risk adult patients with Philadelphia chromosome-negative relapsed or refractory B-cell precursor acute lymphoblastic leukemia, one of the most aggressive B-cell malignancies. Results showed median overall survival was 7.7 months for Blincyto versus four months for SOC. The TOWER study is the confirmatory study for the Phase 2 trial that supported the FDA's accelerated approval designation for Blincyto in 2014. The survival benefit for Blincyto was independent of allogeneic stem cell transplant. Improvement in OS was generally consistent regardless of age, prior salvage therapy or prior alloSCT. Remission rates were also higher for Blincyto, 34% of complete remission, versus 16% in the SOC group. Among patients with complete remission or complete remission with partial or incomplete hematologic recovery, 76% in the Blincyto group versus 48% in the SOC group achieved minimal residual disease negative status. Safety results among subjects who received Blincyto were comparable to those seen in the Phase 2 studies in adult patients with Ph- relapsed or refractory B-cell precursor ALL.

  • 09

    Mar

  • 17

    Mar

  • 21

    Mar

  • 19

    Jul

AMGN Amgen
$178.24

1.71 (0.97%)

02/13/17
BMOC
02/13/17
NO CHANGE
BMOC
Data bodes well for Amgen drug, says BMO Capital
BMO Capital analyst M. Ian Somaiya says that studies continue to indicate that reducing LDL-C levels continuously lower the risk of adverse cardiovascular events. As a result, the analyst is more confident that Amgen's Repatha drug can demonstrate a 20% improvement in cardiovascular outcomes. After conducting checks, he believes that such an outcome would enable the drug to meet his estimates which are 30%-50% above those of the Street. He raised his price target on Amgen to $212 from $202 and keeps an Outperform rating on the stock.
02/16/17
GSCO
02/16/17
DOWNGRADE
Target $417
GSCO
Neutral
Regeneron downgraded to Neutral from Buy at Goldman
Goldman Sachs analyst Terence Flynn downgraded Regeneron Pharmaceuticals (REGN) to Neutral from Buy citing valuation with the stock within 9% of his unchanged $417 price target. The analyst sees less upside potential relative to Regeneron's large-cap peers Amgen (AMGN) and Alexion (ALXN). Flynn adds that his revenue estimates for Regeneron's 2018-2020 are no longer above consensus following the PCSK9 litigation and recent Eylea guidance. The stock closed yesterday up $7.47 to $384.00.
02/22/17
OPCO
02/22/17
NO CHANGE
Target $189
OPCO
Outperform
Amgen price target raised to $189 from $175 at Oppenheimer
Oppenheimer analyst Leah Rush Cann raised her price target for Amgen to $189 from $175 after the company recently reported label expansion filings and FDA approvals. The analyst reiterates an Outperform rating on the shares.
02/23/17
LEER
02/23/17
NO CHANGE
LEER
AbbVie has the best near/mid-term outlook, says Leerink
Comparing AbbVie (ABBV), Amgen (AMGN) and Gilead (GILD) by assessing the earnings quality, earnings momentum, margin trajectory, and dividend and cash flow valuation metrics, Leerink analyst Geoffrey Porges says his analysis suggests that AbbVie offers "more attractive fundamentals" based on earnings momentum and dividend yield, and is also the only company of the three that is likely to show sustained improvements in operating margin and cash flow over the next four years. The analyst finds that AbbVie has the best near-to-mid-term outlook at a relatively discounted valuation compared to these similarly sized, value biopharma peers.

TODAY'S FREE FLY STORIES

01:55
11/22/17
11/22
01:55
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01:55
Conference/Events
Morgan Stanley analysts hold an analyst/industry conference call »

Sales Specialist Prowse…

DE

Deere

$139.23

2.31 (1.69%)

20:25
11/21/17
11/21
20:25
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20:25
Earnings
Notable companies reporting before tomorrow's open »

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PCRX

Pacira

$42.65

0.45 (1.07%)

19:24
11/21/17
11/21
19:24
11/21/17
19:24
Recommendations
Pacira analyst commentary at BMO Capital »

October Symphony data…

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CEIX

CONSOL Energy

, ICON

Iconix Brand

$2.55

0.28 (12.33%)

19:00
11/21/17
11/21
19:00
11/21/17
19:00
Hot Stocks
S&P announces changes to S&P SmallCap 600 index »

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CEIX

CONSOL Energy

ICON

Iconix Brand

$2.55

0.28 (12.33%)

CNX

Consol

$16.27

0.23 (1.43%)

PDFS

PDF Solutions

$15.86

0.11 (0.70%)

BBOX

Black Box

$4.15

0.55 (15.28%)

03/08/13
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TIVO

TiVo

$17.65

0.15 (0.86%)

, CMCSA

Comcast

$36.42

0.59 (1.65%)

18:52
11/21/17
11/21
18:52
11/21/17
18:52
Recommendations
TiVo, Comcast analyst commentary at JPMorgan »

ITC ruling a…

TIVO

TiVo

$17.65

0.15 (0.86%)

CMCSA

Comcast

$36.42

0.59 (1.65%)

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GKOS

Glaukos

$25.35

-2.86 (-10.14%)

18:48
11/21/17
11/21
18:48
11/21/17
18:48
Recommendations
Glaukos analyst commentary at Piper Jaffray »

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DIS

Disney

$103.00

0.25 (0.24%)

, CMCSA

Comcast

$36.42

0.59 (1.65%)

18:31
11/21/17
11/21
18:31
11/21/17
18:31
Periodicals
Hulu sued for failure to offer audio service for blind subscribers, NY Post says »

Advocacy groups are suing…

DIS

Disney

$103.00

0.25 (0.24%)

CMCSA

Comcast

$36.42

0.59 (1.65%)

CMCSK

Comcast

TWX

Time Warner

$89.56

1.85 (2.11%)

FOX

21st Century Fox

$30.10

0.2 (0.67%)

FOXA

21st Century Fox

$30.88

0.22 (0.72%)

03/08/13
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03/06/13
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MGA

Magna

$54.29

0.37 (0.69%)

18:23
11/21/17
11/21
18:23
11/21/17
18:23
Hot Stocks
Magna announces two share repurchase programs »

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PTLA

Portola Pharmaceuticals

$50.80

1.29 (2.61%)

18:23
11/21/17
11/21
18:23
11/21/17
18:23
Hot Stocks
Portola: FDA extends review period for PAS for Bevyxxa »

Portola Pharmaceuticals…

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  • 02

    Feb

PBMD

Prima BioMed

$1.65

-0.03 (-1.79%)

18:09
11/21/17
11/21
18:09
11/21/17
18:09
Hot Stocks
Prima BioMed secures European patent grant for lead product IMP321 in cancer »

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CPRT

Copart

$36.70

0.39 (1.07%)

18:06
11/21/17
11/21
18:06
11/21/17
18:06
Earnings
Copart reports Q1 non-GAAP EPS 33c, consensus 27c »

Reports Q1 revenue 419.2M…

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  • 22

    Nov

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PCTY

Paylocity

$47.79

-0.64 (-1.32%)

18:01
11/21/17
11/21
18:01
11/21/17
18:01
Hot Stocks
Paylocity chairman sells 736,845 common shares »

In a regulatory filing,…

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  • 21

    Nov

MDC

M.D.C. Holdings

$35.10

0.91 (2.66%)

18:01
11/21/17
11/21
18:01
11/21/17
18:01
Hot Stocks
M.D.C. Holdings declares special 8% stock dividend »

M.D.C. Holdings announced…

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PDFS

PDF Solutions

$15.86

0.11 (0.70%)

, BBOX

Black Box

$4.15

0.55 (15.28%)

17:59
11/21/17
11/21
17:59
11/21/17
17:59
Hot Stocks
Breaking Hot Stocks news story on PDF Solutions, Black Box »

PDF Solutions to replace…

PDFS

PDF Solutions

$15.86

0.11 (0.70%)

BBOX

Black Box

$4.15

0.55 (15.28%)

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HPQ

HP Inc.

$22.46

0.34 (1.54%)

17:58
11/21/17
11/21
17:58
11/21/17
17:58
Hot Stocks
Breaking Hot Stocks news story on HP Inc. »

HP Inc. sees pressure on…

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  • 21

    Nov

CEIX

CONSOL Energy

, ICON

Iconix Brand

$2.55

0.28 (12.33%)

17:57
11/21/17
11/21
17:57
11/21/17
17:57
Hot Stocks
Breaking Hot Stocks news story on CONSOL Energy, Iconix Brand »

CONSOL Energy to replace…

CEIX

CONSOL Energy

ICON

Iconix Brand

$2.55

0.28 (12.33%)

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HPQ

HP Inc.

$22.46

0.34 (1.54%)

17:53
11/21/17
11/21
17:53
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17:53
Hot Stocks
Breaking Hot Stocks news story on HP Inc. »

HP Inc. says returned…

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  • 21

    Nov

TMQ

Trilogy Metals

$0.92

-0.0211 (-2.25%)

17:53
11/21/17
11/21
17:53
11/21/17
17:53
Syndicate
Breaking Syndicate news story on Trilogy Metals »

Trilogy Metals files to…

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TRNO

Terreno Realty

$37.74

0.74 (2.00%)

17:50
11/21/17
11/21
17:50
11/21/17
17:50
Initiation
Terreno Realty initiated at National Securities »

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  • 14

    Dec

HPQ

HP Inc.

$22.47

0.355 (1.61%)

17:47
11/21/17
11/21
17:47
11/21/17
17:47
Hot Stocks
HP Inc.: 'Stay tuned' for news on metal 3D printing »

Says plans to introduce…

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  • 21

    Nov

THC

Tenet

$13.34

0.17 (1.29%)

17:47
11/21/17
11/21
17:47
11/21/17
17:47
Initiation
Tenet initiated at William Blair »

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LPNT

LifePoint

$43.85

0.65 (1.50%)

17:47
11/21/17
11/21
17:47
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17:47
Initiation
LifePoint initiated at William Blair »

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LHCG

LHC Group

$67.98

1.46 (2.19%)

17:46
11/21/17
11/21
17:46
11/21/17
17:46
Initiation
LHC Group initiated at William Blair »

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  • 12

    Dec

  • 13

    Dec

HLS

HealthSouth

$48.46

0.85 (1.79%)

17:46
11/21/17
11/21
17:46
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17:46
Initiation
HealthSouth initiated at William Blair »

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HCA

HCA Healthcare

$75.89

1.28 (1.72%)

17:46
11/21/17
11/21
17:46
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17:46
Initiation
HCA Healthcare initiated at William Blair »

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  • 06

    Dec

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