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ABBV

AbbVie

$63.78

0.33 (0.52%)

05:44
04/21/17
04/21
05:44
04/21/17
05:44

AbbVie says 8 weeks of treatment with P/G achieved high SVR 12 rates

AbbVie announced high SVR12 rates were achieved with 8 weeks of treatment with its investigational, once-daily, ribavirin-free, pan-genotypic regimen of glecaprevir/pibrentasvir, or G/P, in patients with challenging to treat genotype 3, or GT3, chronic hepatitis C virus, or HCV, infection. In results from the Phase 3 ENDURANCE-3 study, 95% of GT3 chronic HCV infected patients without cirrhosis and who are new to treatment achieved sustained virologic response at 12 weeks post-treatment, or SVR12, following 8 weeks of treatment with G/P. These new data will be featured as an oral presentation today at The International Liver Congress 2017 in Amsterdam, The Netherlands. As well as evaluating 8 weeks of treatment with G/P, the ENDURANCE-3 study was designed to evaluate whether 12 weeks of G/P is non-inferior to 12 weeks of sofosbuvir plus daclatasvir, or SOF+DCV, a current standard of care for GT3 chronic HCV infected patients. SVR12 rates of 95% were seen in both 8 weeks and 12 weeks of treatment with G/P.1 Additionally, 12 weeks of treatment with G/P was demonstrated to be non-inferior to 12 weeks of treatment with SOF+DCV.

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ABBV AbbVie
$63.78

0.33 (0.52%)

04/17/17
JEFF
04/17/17
NO CHANGE
Target $97
JEFF
Buy
Jefferies sees Lilly trading down 5% on baricitinib CRL
Jefferies analyst Jeffrey Holford expects Eli Lilly (LLY) to trade down around 5% after the company and Incyte (INCY) received a complete response letter from the FDA for baricitinib. A significant delay to the U.S. approval of baricitinib could hit Lilly's mid-term earnings and valuation by up to 8%-10%, Holford tells investors in a research note. He notes, however, that the cause or extent of the delay is unclear at this point. Holford keeps a Buy rating on Lilly with a $97 price target. The analyst views the baricitinib CRL as a positive for AbbVie's (ABBV) "best in class" JAK inhibitor, ABT-4494. A delay to baricitinib could result in ABT-494 reaching the U.S. market before baricitinib, the analyst contends.
04/20/17
LEER
04/20/17
NO CHANGE
Target $71
LEER
Market Perform
AbbVie veliparib not competitive with other products, says Leerink
Leerink analyst Geoffrey Porges notes that AbbVie announced failed top-line results for its PARP inhibitor veliparib in combination with chemotherapy for metastatic squamous NSCLC and early TNBC. While two disappointing trials would not normally completely doom a program, the analyst says that the lack of effect confirms his view that veliparib has limited activity and is not competitive with other products in this class. For this reason, Porges is taking the probability of success of the program to zero. The analyst reiterated a Market Perform rating on the stock and lowered his price target on the shares to $71 from $72.
04/20/17
JEFF
04/20/17
NO CHANGE
Target $90
JEFF
Buy
AbbVie cancer drug failure should have little impact, says Jefferies
Jefferies analyst Jeffrey Holford expects the Phase III failure of veliparib to have little impact on AbbVie shares. The analyst says expectations were low and that the drug accounted for less than 1% of his mid-term revenues estimates. He keeps a Buy rating on AbbVie with a $90 price target.
04/20/17
RHCO
04/20/17
NO CHANGE
RHCO
Tesaro has no negative read through from AbbVie failure, says SunTrust
SunTrust analyst Peter Lawson says that there is "no impact" on Tesaro's (TSRO) niraparib from the failure of AbbVie's (ABBV) PARP inhibitor, veliparib, in triple negative breast cancer and lung cancer. The analyst believes that niraparib could be more effective than veliparib. Additionally, he notes that during its trial veliparib was used in combination with chemotherapy, while niraparib will be combined with Merck's (MRK) Keytruda for its trial. He thinks that the pairing with Keytruda will result in more effective treatment. The analyst keeps a $235 price target and a Buy rating on Tesaro.

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VCEL

Vericel

$6.55

0.3 (4.80%)

12:46
01/18/18
01/18
12:46
01/18/18
12:46
Hot Stocks
RTW Invesmtents reports 5.04% passive stake in Vericel »

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DDAIF

Daimler AG

$90.67

0.17 (0.19%)

12:45
01/18/18
01/18
12:45
01/18/18
12:45
Periodicals
Daimler, Bosch suffer walkouts in industrial labor dispute, Reuters says »

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FOLD

Amicus

$15.78

0.71 (4.71%)

12:45
01/18/18
01/18
12:45
01/18/18
12:45
Options
Amicus call volume above normal and directionally bullish »

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JPM

JPMorgan

$113.44

0.45 (0.40%)

12:41
01/18/18
01/18
12:41
01/18/18
12:41
Periodicals
JPMorgan sued for over $875M by Nigeria over 2011 oilfield deal, Reuters reports »

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FSNN

Fusion Telecommunications

$3.83

-0.03 (-0.78%)

12:33
01/18/18
01/18
12:33
01/18/18
12:33
Hot Stocks
Cooper Creek Partners reports 5.17% passive stake in Fusion Telecommunications »

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AMZN

Amazon.com

$1,295.00

-9.86 (-0.76%)

, MS

Morgan Stanley

$55.59

0.235 (0.42%)

12:29
01/18/18
01/18
12:29
01/18/18
12:29
General news
On The Fly: Top stock stories at midday »

Stock futures were above…

AMZN

Amazon.com

$1,295.00

-9.86 (-0.76%)

MS

Morgan Stanley

$55.59

0.235 (0.42%)

LGF.A

Lionsgate

$34.99

2.71 (8.40%)

CBS

CBS

$61.09

2.19 (3.72%)

VIAB

Viacom

$31.96

0.58 (1.85%)

VIA

Viacom

$37.85

0.95 (2.57%)

GNC

GNC Holdings

$4.95

1.48 (42.65%)

PTC

PTC

$66.70

1.41 (2.16%)

AA

Alcoa

$52.37

-4.6199 (-8.11%)

ENDP

Endo

$7.69

-0.32 (-4.00%)

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IP

International Paper

$62.23

0.74 (1.20%)

12:25
01/18/18
01/18
12:25
01/18/18
12:25
Options
International Paper call volume above normal and directionally bullish »

Bullish option flow…

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  • 01

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FMC

FMC Corporation

$88.41

-5.45 (-5.81%)

12:23
01/18/18
01/18
12:23
01/18/18
12:23
Recommendations
FMC Corporation analyst commentary  »

FMC Corporation pullback…

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BBBY

Bed Bath & Beyond

$23.40

0.39 (1.69%)

12:21
01/18/18
01/18
12:21
01/18/18
12:21
Hot Stocks
Bed Bath & Beyond recalls Hudson Comforters on mold exposure 

Reference Link

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COLB

Columbia Banking

$45.94

0.36 (0.79%)

12:19
01/18/18
01/18
12:19
01/18/18
12:19
Hot Stocks
Columbia Bank names Lisa Dow chief risk officer »

Columbia Bank announced…

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  • 13

    Mar

ACOR

Acorda Therapeutics

$24.75

-0.3 (-1.20%)

12:17
01/18/18
01/18
12:17
01/18/18
12:17
Periodicals
Acorda Therapeutics jumps after web report about takeover approach »

According to a report…

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$NSD

NASDAQ Market Internals

12:17
01/18/18
01/18
12:17
01/18/18
12:17
Technical Analysis
NASDAQ market internals summary »

Volume is average for…

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$NYE

NYSE Market Internals

12:16
01/18/18
01/18
12:16
01/18/18
12:16
Technical Analysis
NYSE market internals summary »

Volume is average for…

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12:15
01/18/18
01/18
12:15
01/18/18
12:15
General news
Atlanta Fed's Q4 GDPNow estimate was raised to 3.4%: »

Atlanta Fed's Q4…

AMZN

Amazon.com

$1,295.00

-9.86 (-0.76%)

, SNE

Sony

$49.18

-0.6438 (-1.29%)

12:12
01/18/18
01/18
12:12
01/18/18
12:12
Periodicals
Amazon looks to compete in commercial films, less indies, Reuters says »

Amazon (AMZN) is looking…

AMZN

Amazon.com

$1,295.00

-9.86 (-0.76%)

SNE

Sony

$49.18

-0.6438 (-1.29%)

FOX

21st Century Fox

$36.49

0.7 (1.96%)

TWX

Time Warner

$92.31

0.14 (0.15%)

VIA

Viacom

$37.85

0.95 (2.57%)

CMCSA

Comcast

$41.68

-0.14 (-0.33%)

DIS

Disney

$111.33

-0.64 (-0.57%)

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MELI

MercadoLibre

$340.45

0.6 (0.18%)

12:10
01/18/18
01/18
12:10
01/18/18
12:10
Options
$45.5M option print in MercadoLibre »

$45.5M option print in…

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FMC

FMC Corporation

$87.26

-6.6001 (-7.03%)

, SQM

SQM

$57.76

-1.79 (-3.01%)

12:06
01/18/18
01/18
12:06
01/18/18
12:06
Recommendations
FMC Corporation, SQM analyst commentary  »

FMC Corporation selloff…

FMC

FMC Corporation

$87.26

-6.6001 (-7.03%)

SQM

SQM

$57.76

-1.79 (-3.01%)

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  • 13

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AXP

American Express

$100.20

-0.56 (-0.56%)

, V

Visa

$122.37

0.39 (0.32%)

12:06
01/18/18
01/18
12:06
01/18/18
12:06
Earnings
On The Fly: What to watch in credit card space earnings reports »

American Express (AXP) is…

AXP

American Express

$100.20

-0.56 (-0.56%)

V

Visa

$122.37

0.39 (0.32%)

MA

MasterCard

$164.92

0.6 (0.37%)

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DIS

Disney

$111.22

-0.75 (-0.67%)

12:03
01/18/18
01/18
12:03
01/18/18
12:03
Hot Stocks
Disney, Twitch announce multi-year content partnership »

Social video service…

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INTC

Intel

$44.39

1.25 (2.90%)

12:01
01/18/18
01/18
12:01
01/18/18
12:01
Hot Stocks
Intel debuts technologies, including RealSense Volumetric Content Capture »

During the 2018 Sundance…

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FMC

FMC Corporation

$87.26

-6.6 (-7.03%)

, SQM

SQM

$57.49

-2.065 (-3.47%)

12:00
01/18/18
01/18
12:00
01/18/18
12:00
Recommendations
FMC Corporation, SQM analyst commentary  »

FMC Corporation pullback…

FMC

FMC Corporation

$87.26

-6.6 (-7.03%)

SQM

SQM

$57.49

-2.065 (-3.47%)

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SBAC

SBA Communications

$161.47

1.62 (1.01%)

12:00
01/18/18
01/18
12:00
01/18/18
12:00
Options
One-day put sellers in SBA Comm »

One-day put sellers in…

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LGF.A

Lionsgate

$33.90

1.62 (5.02%)

, CBS

CBS

$61.09

2.19 (3.72%)

11:58
01/18/18
01/18
11:58
01/18/18
11:58
Hot Stocks
Lionsgate jumps after report on potential takeover interest »

Shares of Lionsgate…

LGF.A

Lionsgate

$33.90

1.62 (5.02%)

CBS

CBS

$61.09

2.19 (3.72%)

VIAB

Viacom

$31.96

0.58 (1.85%)

VIA

Viacom

$37.85

0.95 (2.57%)

AMZN

Amazon.com

$1,295.00

-9.86 (-0.76%)

VZ

Verizon

$52.78

1.055 (2.04%)

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    Feb

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    Mar

ADP

ADP

$122.05

2.66 (2.23%)

, CSOD

Cornerstone OnDemand

$39.28

0.34 (0.87%)

11:52
01/18/18
01/18
11:52
01/18/18
11:52
Conference/Events
Stephens enterprise software analyst holds analyst/industry conference call »

Enterprise Software…

ADP

ADP

$122.05

2.66 (2.23%)

CSOD

Cornerstone OnDemand

$39.28

0.34 (0.87%)

MSFT

Microsoft

$90.14

1.79 (2.03%)

ORCL

Oracle

$50.26

-0.01 (-0.02%)

PAYC

Paycom

$88.34

-0.01 (-0.01%)

PCTY

Paylocity

$49.46

0.71 (1.46%)

SAP

SAP

$111.45

0.2601 (0.23%)

ULTI

Ultimate Software

$226.26

3.48 (1.56%)

WDAY

Workday

$112.26

2.17 (1.97%)

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DXCM

Dexcom

$56.32

-0.09 (-0.16%)

, ABT

Abbott

$58.77

-0.22 (-0.37%)

11:51
01/18/18
01/18
11:51
01/18/18
11:51
Hot Stocks
Dexcom dips with Cigna deeming Abbott's Libre medically necessary »

Shares of Dexcom (DXCM)…Reference Link

DXCM

Dexcom

$56.32

-0.09 (-0.16%)

ABT

Abbott

$58.77

-0.22 (-0.37%)

CI

Cigna

$218.45

-1.915 (-0.87%)

03/08/13
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