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ABBV

AbbVie

$63.78

0.33 (0.52%)

05:44
04/21/17
04/21
05:44
04/21/17
05:44

AbbVie says 8 weeks of treatment with P/G achieved high SVR 12 rates

AbbVie announced high SVR12 rates were achieved with 8 weeks of treatment with its investigational, once-daily, ribavirin-free, pan-genotypic regimen of glecaprevir/pibrentasvir, or G/P, in patients with challenging to treat genotype 3, or GT3, chronic hepatitis C virus, or HCV, infection. In results from the Phase 3 ENDURANCE-3 study, 95% of GT3 chronic HCV infected patients without cirrhosis and who are new to treatment achieved sustained virologic response at 12 weeks post-treatment, or SVR12, following 8 weeks of treatment with G/P. These new data will be featured as an oral presentation today at The International Liver Congress 2017 in Amsterdam, The Netherlands. As well as evaluating 8 weeks of treatment with G/P, the ENDURANCE-3 study was designed to evaluate whether 12 weeks of G/P is non-inferior to 12 weeks of sofosbuvir plus daclatasvir, or SOF+DCV, a current standard of care for GT3 chronic HCV infected patients. SVR12 rates of 95% were seen in both 8 weeks and 12 weeks of treatment with G/P.1 Additionally, 12 weeks of treatment with G/P was demonstrated to be non-inferior to 12 weeks of treatment with SOF+DCV.

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ABBV AbbVie
$63.78

0.33 (0.52%)

04/20/17
RHCO
04/20/17
NO CHANGE
RHCO
Tesaro has no negative read through from AbbVie failure, says SunTrust
SunTrust analyst Peter Lawson says that there is "no impact" on Tesaro's (TSRO) niraparib from the failure of AbbVie's (ABBV) PARP inhibitor, veliparib, in triple negative breast cancer and lung cancer. The analyst believes that niraparib could be more effective than veliparib. Additionally, he notes that during its trial veliparib was used in combination with chemotherapy, while niraparib will be combined with Merck's (MRK) Keytruda for its trial. He thinks that the pairing with Keytruda will result in more effective treatment. The analyst keeps a $235 price target and a Buy rating on Tesaro.
04/20/17
JEFF
04/20/17
NO CHANGE
Target $90
JEFF
Buy
AbbVie cancer drug failure should have little impact, says Jefferies
Jefferies analyst Jeffrey Holford expects the Phase III failure of veliparib to have little impact on AbbVie shares. The analyst says expectations were low and that the drug accounted for less than 1% of his mid-term revenues estimates. He keeps a Buy rating on AbbVie with a $90 price target.
04/20/17
LEER
04/20/17
NO CHANGE
Target $71
LEER
Market Perform
AbbVie veliparib not competitive with other products, says Leerink
Leerink analyst Geoffrey Porges notes that AbbVie announced failed top-line results for its PARP inhibitor veliparib in combination with chemotherapy for metastatic squamous NSCLC and early TNBC. While two disappointing trials would not normally completely doom a program, the analyst says that the lack of effect confirms his view that veliparib has limited activity and is not competitive with other products in this class. For this reason, Porges is taking the probability of success of the program to zero. The analyst reiterated a Market Perform rating on the stock and lowered his price target on the shares to $71 from $72.
04/17/17
JEFF
04/17/17
NO CHANGE
Target $97
JEFF
Buy
Jefferies sees Lilly trading down 5% on baricitinib CRL
Jefferies analyst Jeffrey Holford expects Eli Lilly (LLY) to trade down around 5% after the company and Incyte (INCY) received a complete response letter from the FDA for baricitinib. A significant delay to the U.S. approval of baricitinib could hit Lilly's mid-term earnings and valuation by up to 8%-10%, Holford tells investors in a research note. He notes, however, that the cause or extent of the delay is unclear at this point. Holford keeps a Buy rating on Lilly with a $97 price target. The analyst views the baricitinib CRL as a positive for AbbVie's (ABBV) "best in class" JAK inhibitor, ABT-4494. A delay to baricitinib could result in ABT-494 reaching the U.S. market before baricitinib, the analyst contends.

TODAY'S FREE FLY STORIES

SITO

SITO Mobile

$3.66

0.02 (0.55%)

16:43
06/23/17
06/23
16:43
06/23/17
16:43
Hot Stocks
SITO Mobile chairman Paul Pressler resigns »

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REGN

Regeneron

$517.33

-9.2 (-1.75%)

, CELG

Celgene

$134.31

0.63 (0.47%)

16:41
06/23/17
06/23
16:41
06/23/17
16:41
General news
S&P sees mild weekly gain, Nasdaq outperforms as biotech shines »

The S&P finished the…

REGN

Regeneron

$517.33

-9.2 (-1.75%)

CELG

Celgene

$134.31

0.63 (0.47%)

GILD

Gilead

$70.54

0.06 (0.09%)

BIIB

Biogen

$280.32

-0.25 (-0.09%)

VRTX

Vertex

$133.50

-2.03 (-1.50%)

AMGN

Amgen

$172.50

-1.32 (-0.76%)

ABBV

AbbVie

$72.64

-0.54 (-0.74%)

ALXN

Alexion

$126.07

-0.16 (-0.13%)

BA

Boeing

$202.23

2.79 (1.40%)

ORCL

Oracle

$50.95

0.65 (1.29%)

EQT

EQT Corporation

$56.19

4.16 (8.00%)

RICE

Rice Energy

$25.65

1.62 (6.74%)

SYK

Stryker

$141.12

-0.1 (-0.07%)

NVDQ

Novadaq

$11.78

-0.02 (-0.17%)

PRXL

Parexel

$86.80

-0.31 (-0.36%)

LH

LabCorp

$151.62

1.28 (0.85%)

ICLR

ICON plc

$96.37

-0.26 (-0.27%)

NKE

Nike

$52.85

0.45 (0.86%)

AMZN

Amazon.com

$1,003.74

2.44 (0.24%)

INTC

Intel

$34.19

-0.17 (-0.49%)

AMD

AMD

$14.15

-0.23 (-1.60%)

LZB

La-Z-Boy

$32.30

0.7 (2.22%)

RHT

Red Hat

$99.42

0.54 (0.55%)

AAL

American Airlines

$48.63

-0.34 (-0.69%)

HCA

HCA Holdings

$86.24

0.1 (0.12%)

LPNT

LifePoint

$65.50

-1.6 (-2.38%)

THC

Tenet

$18.52

-0.38 (-2.01%)

SCS

Steelcase

$13.65

-0.45 (-3.19%)

ACN

Accenture

$122.74

0.66 (0.54%)

BBBY

Bed Bath & Beyond

$29.65

-4.09 (-12.12%)

BBRY

BlackBerry

$9.71

-1.35 (-12.21%)

BAC

Bank of America

$22.82

-0.11 (-0.48%)

C

Citi

$63.41

-0.21 (-0.33%)

GS

Goldman Sachs

$217.19

-2.58 (-1.17%)

JPM

JPMorgan

$86.86

-0.16 (-0.18%)

MS

Morgan Stanley

$43.69

-0.92 (-2.06%)

WFC

Wells Fargo

$52.45

-0.04 (-0.08%)

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16:39
06/23/17
06/23
16:39
06/23/17
16:39
General news
Moody's raises Greece rating to Caa2 from Caa3, outlook to positive from stable »

Moody's has upgraded…

CFCO

CF Corporation

$11.42

-0.04 (-0.35%)

16:38
06/23/17
06/23
16:38
06/23/17
16:38
Hot Stocks
Breaking Hot Stocks news story on CF Corporation »

Mason Capital reports…

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AKS

AK Steel

$6.65

0.35 (5.56%)

, X

U.S. Steel

$22.25

1.18 (5.60%)

16:34
06/23/17
06/23
16:34
06/23/17
16:34
General news
On The Fly: Top stock stories for Friday »

Stocks opened in quiet…

AKS

AK Steel

$6.65

0.35 (5.56%)

X

U.S. Steel

$22.25

1.18 (5.60%)

PTLA

Portola Pharmaceuticals

$56.13

17.88 (46.75%)

BAC

Bank of America

$22.82

-0.11 (-0.48%)

C

Citi

$63.41

-0.21 (-0.33%)

GS

Goldman Sachs

$217.19

-2.58 (-1.17%)

JPM

JPMorgan

$86.86

-0.16 (-0.18%)

MS

Morgan Stanley

$43.69

-0.92 (-2.06%)

WFC

Wells Fargo

$52.45

-0.04 (-0.08%)

SNCR

Synchronoss

$16.24

4.06 (33.33%)

BBBY

Bed Bath & Beyond

$29.65

-4.09 (-12.12%)

BBRY

BlackBerry

$9.71

-1.35 (-12.21%)

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FMC

FMC Corporation

$74.78

0.52 (0.70%)

16:31
06/23/17
06/23
16:31
06/23/17
16:31
Hot Stocks
FMC Corporation to sell Omega-3 business to Pelagia AS, terms not disclosed »

FMC Corporation has…

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16:30
06/23/17
06/23
16:30
06/23/17
16:30
Options
Preliminary option volume of 15.0M today »

Preliminary option volume…

ESNC

EnSync

$0.33

0.0151 (4.79%)

16:25
06/23/17
06/23
16:25
06/23/17
16:25
Syndicate
Breaking Syndicate news story on EnSync »

EnSync files $25M mixed…

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  • 22

    Jun

PTLA

Portola Pharmaceuticals

$56.13

17.88 (46.75%)

16:25
06/23/17
06/23
16:25
06/23/17
16:25
Conference/Events
Portola Pharmaceuticals hold a conference call »

Management holds a…

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  • 23

    Jun

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    Jun

DTE

DTE Energy

$108.89

-0.69 (-0.63%)

16:24
06/23/17
06/23
16:24
06/23/17
16:24
Earnings
DTE Energy backs FY17 operating EPS view $5.15-$5.46, consensus $5.33 »

DTE Energy will meet with…

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  • 06

    Jul

$NSD

NASDAQ Market Internals

16:17
06/23/17
06/23
16:17
06/23/17
16:17
Technical Analysis
NASDAQ market internals summary »

Volume was above average…

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VHI

Valhi Inc

$3.29

0.14 (4.44%)

16:16
06/23/17
06/23
16:16
06/23/17
16:16
Hot Stocks
Valhi Inc termiantes purchase deal for sale of Waste Control Specialists »

As previously announced,…

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$NYE

NYSE Market Internals

16:16
06/23/17
06/23
16:16
06/23/17
16:16
Technical Analysis
NYSE market internals summary »

Volume was average for…

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GBL

GAMCO Investors

$29.63

-0.24 (-0.80%)

, LSXMA

Liberty SiriusXM

$40.83

0.79 (1.97%)

16:14
06/23/17
06/23
16:14
06/23/17
16:14
Hot Stocks
Breaking Hot Stocks news story on GAMCO Investors, Liberty SiriusXM »

Gabelli reports 5.22%…

GBL

GAMCO Investors

$29.63

-0.24 (-0.80%)

LSXMA

Liberty SiriusXM

$40.83

0.79 (1.97%)

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WETF

WisdomTree

$9.98

-0.11 (-1.09%)

16:13
06/23/17
06/23
16:13
06/23/17
16:13
Hot Stocks
WisdomTree to close, liquidate three ETFs »

WisdomTree announced…

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CONN

Conn's

$17.10

0.15 (0.88%)

16:11
06/23/17
06/23
16:11
06/23/17
16:11
Hot Stocks
Breaking Hot Stocks news story on Conn's »

Point72 Asset reports…

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WMT

Wal-Mart

$74.87

-0.655 (-0.87%)

, WFM

Whole Foods

$42.95

-0.255 (-0.59%)

16:11
06/23/17
06/23
16:11
06/23/17
16:11
Periodicals
Wal-Mart not weighing offer for Whole Foods, Reuters reports »

Wal-Mart (WMT) is not…

WMT

Wal-Mart

$74.87

-0.655 (-0.87%)

WFM

Whole Foods

$42.95

-0.255 (-0.59%)

AMZN

Amazon.com

$1,003.74

2.44 (0.24%)

03/08/13
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  • 26

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APDN

Applied DNA Sciences

$1.09

0.06 (5.83%)

16:10
06/23/17
06/23
16:10
06/23/17
16:10
Hot Stocks
Applied DNA Sciences receives order to tag 27.5M pounds of cotton »

Applied DNA Sciences is…

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MOCO

Mocon

16:08
06/23/17
06/23
16:08
06/23/17
16:08
Hot Stocks
Gabelli liquidates stake in Mocon »

As a result of the…

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TKTDY

Takata

$3.15

1.2199 (63.21%)

16:03
06/23/17
06/23
16:03
06/23/17
16:03
Periodicals
Takata to seek bankruptcy protection as soon as Sunday, WSJ reports »

Takata intends to seek…

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TIPT

Tiptree Financial

16:02
06/23/17
06/23
16:02
06/23/17
16:02
Hot Stocks
Tiptree Financial repurchases 1M shares from Nomura Securities »

Tiptree has repurchased…

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PFBC

Preferred Bank

16:01
06/23/17
06/23
16:01
06/23/17
16:01
Hot Stocks
Preferred Bank raises quarterly dividend 11% to 20c per share »

Preferred Bank reported…

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AMGN

Amgen

16:01
06/23/17
06/23
16:01
06/23/17
16:01
Hot Stocks
Amgen receives positive CHMP opinion to expand use of Mimpara »

Amgen announced that the…

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WFM

Whole Foods

$43.20

-0.06 (-0.14%)

, WMT

Wal-Mart

$74.66

-0.86 (-1.14%)

15:56
06/23/17
06/23
15:56
06/23/17
15:56
Periodicals
Wal-Mart not considering bid for Whole Foods, Reuters says 

Reuters cites a source.

WFM

Whole Foods

$43.20

-0.06 (-0.14%)

WMT

Wal-Mart

$74.66

-0.86 (-1.14%)

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PBR

Petrobras

$7.77

-0.03 (-0.38%)

, FTI

TechnipFMC

$26.69

-0.045 (-0.17%)

15:30
06/23/17
06/23
15:30
06/23/17
15:30
Periodicals
Petrobras seeks to change riser contract with TechnipFMC, Reuters reports »

Petrobras (PBR) is in…

PBR

Petrobras

$7.77

-0.03 (-0.38%)

FTI

TechnipFMC

$26.69

-0.045 (-0.17%)

03/08/13
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