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EIGR

Eiger BioPharmaceuticals

08:04
04/21/17
04/21
08:04
04/21/17
08:04

Eiger BioPharmaceuticals reports Phase 2 results for lonafarnib at ILC

Eiger BioPharmaceuticals announced additional lonafarnib data from the LOWR HDV Program presented at The International Liver Congress in Amsterdam. After 24 weeks of treatment, all-oral lonafarnib-based regimens suppressed Hepatitis Delta Virus-RNA below the limit of quantitation in 36% of patients, and 60% achieved ALT normalization. The addition of PEG IFN to LNF 25 mg BID + RTV suppressed HDV-RNA below the limit of quantitation in 80% of patients, and 78% achieved ALT normalization. In patients treated for 48 weeks with triple therapy of PEG IFN + LNF 25 mg BID + RTV, PCR-negativity was achieved in 67% of patients at the end of treatment. Additional dosing regimens were also explored in the LOWR program. Anti-HDV activity was observed in all regimens through Week 24 on treatment. HDV viral load returned to baseline in a majority of these patients by Week 24 of post-treatment, suggesting longer-term treatment of all-oral LNF + RTV or triple combination of LNF + RTV + PEG IFN may be necessary to achieve sustained antiviral suppression. Hepatitis Delta is the most aggressive form of viral hepatitis.

  • 06

    Jun

EIGR Eiger BioPharmaceuticals

07/05/16
OPCO
07/05/16
INITIATION
Target $34
OPCO
Outperform
Eiger BioPharmaceuticals initiated with an Outperform at Oppenheimer
Oppenheimer analyst Carlos Solorzano started Eiger BioPharmaceuticals with an Outperform rating and $34 price target.
08/18/16
PIPR
08/18/16
NO CHANGE
Target $35
PIPR
Overweight
Eiger BioPharma raises $20M ahead of Sarasar Data, says Piper Jaffray
Piper Jaffray analyst Edward Tenthoff says that Eiger BioPharmaceuticals ended Q2 with $45.4M and just issued 1.25 million shares at $16.00, raising gross proceeds of $20M, which will fund development of multiple Phase 2 orphan disease candidates into 2018. Tenthoff notes that he is looking for important Phase 2 updates on Sarasar, or lonafarnib, in Hepatitis Delta Virus at AASLD, or American Association for the study of liver diseases, meeting in November. The analyst reiterates an Overweight rating on the stock but lowered his price target on the shares to $35 from $37.50 to account for dilution from the deal.
09/13/16
PIPR
09/13/16
NO CHANGE
Target $35
PIPR
Overweight
Piper sees a trading opportunity in Eiger BioPharmaceuticals
Piper Jaffray analyst Edward Tenthoff believes the recent weakness in shares of Eiger BioPharmaceuticals has created a "compelling trading opportunity" into November's American Association for the Study of Liver Diseases meeting. Eiger will report 24-week Phase II data on Sarasar to treat Hepatitis Delta Virus at the conference, Tenthoff tells investors in a research note. The analyst expects the data to be "highly informative about future development of Sarasar." He reiterates an Overweight rating on Eiger shares with a $35 price target.
04/07/17
PIPR
04/07/17
NO CHANGE
Target $36
PIPR
Overweight
Eiger shares look attractive after selloff, says Piper Jaffray
Piper Jaffray analyst Edward Tenthoff says shares of Eiger BioPharmaceuticals look attractive following yesterday's selloff. The analyst reminds investors that abstracts are often placeholders and that 48-week data on all three Phase II Sarasar studies are likely between April 19-23. The analyst reiterates an Overweight rating on the shares with a $36 price target.

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